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| 1 | Single-center study comparing computed tomography colonography with conventional colonoscopy显示文摘AIM:To compare the results from computed tomography (CT) colonography with conventional colonoscopy in symptomatic patients referred for colonoscopy. METHODS: The study included 227 adult outpatients, mean age 60 years, with appropriate indications for colonoscopy. CT colonography and colonoscopy were performed on the same day in a metropolitan teaching hospital. Colonoscopists were initially blinded to the results of CT colonography but there was segmental unblinding during the procedure. The primary outcome measures were the sensitivity and specificity of CT colonography for the identification of polyps seen at colonoscopy (i.e. analysis by polyp). Secondary outcome measures included an analysis by patient, extracolonic findings at CT colonography, adverse events with both procedures and patient acceptance and preference. RESULTS: Twenty-five patients (11%) were excluded from the analysis because of incomplete colonoscopy or poor bowel preparation that affected either CT colonography, colonoscopy or both procedures. Polyps and masses (usually cancers) were detected at colonoscopy and CT colonography in 35% and 42% of patients, respectively. Of nine patients with a finaldiagnosis of cancer, eight (89%) were identified by CT colonography as masses (5) or polyps (3). For polyps analyzed according to polyp, the overall sensitivity of CT colonography was 50% (95% CI, 39%-61%) but this increased to 71% (95% CI, 52%-85%) for polyps ≥ 6 mm in size. Similarly, specificity for all polyps was 48% (95% CI, 39%-58%) increasing to 67% (95% CI, 56%-76%) for polyps ≥ 6 mm. Adverse events were uncommon but included one colonic perforation at colonoscopy. Patient acceptance was high for both procedures but preference favoured CT colonography. CONCLUSION: Although CT colonography was more sensitive in this study than in some previous studies, the procedure is not yet sensitive enough for widespread application in symptomatic patients. | Ian C Roberts-Thomson Graeme R Tucker Peter J Hewett Peter Cheung Ruben A Sebben EE Win Khoo Julie D Marker Wayne K Clapton | 2008 | World Journal of Gastroenterology2008，14，3： | 4 |
| 2 | Biologically Active Allkylatedcoumarins from Kayeaassamica显示文摘 | Lee K H Chai H B Tamez P A Pezzuto J M Cordell G A Win K K TinWa M | 2003 | Phyto Chemistry2003，64，2： | 1 |
| 3 | The impact of patient expectations On outcomes in four randomized controlled trials of acupuncture in pafients with chronic paln显示文摘 | Linde K Win CM Streng A | 2007 | Pain2007，128，3： | 1 |
| 4 | 'NONOates' (1-substitutes diazen-1-ium-1,2-diolates) as nitric oxide donors:convenient nitric oxide dosage forms显示文摘 | Keefer L K Nims R W Davies K M Win D A | 1996 | Method Enzymol1996，298，： | 1 |
| 5 | Determining the frequency of de novo germline mutations in DNA mismatch repair genes显示文摘 | Win A K Jenkins M A Buchanan D D | 2011 | Aug2011，48，8： | 1 |
| 6 | Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes显示文摘 | Win A K Dowty J G English D R | 2011 | Br J Cancer2011，105，1： | 1 |
| 7 | Discrimination of mango fruit maturity by volatiles using the electronic nose and gas chromatography显示文摘 | LEBRUN M PLOTTO A GOODNER K DUCAMP M N BALD- WIN E | 2008 | Postharvest Biology and Technology2008，48，1： | 1 |
| 8 | Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation:a prospective cohort study显示文摘 | WIN A K YOUNG J P LINDOR N M | 2012 | J Clin Oncol2012，30，9： | 1 |
| 9 | Risks of colorectal and other cancers after endometrial cancer for women with Lynch syndrome显示文摘 | WIN A K UNDOR N M WINSHIP I | 2013 | J Natl Cancer Inst2013，105，4： | 1 |
| 10 | Varietal differences in growth and Cs allocation of blackgram (Vigna mungo) under water stress显示文摘 | WIN K T OO A Z HAN P A | 2015 | Environmental & Experimental Botany2015，109，： | 1 |
| 11 | Environmental study of the impact of greenery in an institutional cam-pus in the tropics显示文摘 | Wong N H Jusuf S K Win A A L | 2007 | Building and Environment2007，42，8： | 1 |
| 12 | Parametric and noroarmnetric statistical modelling of crop yield : implications for pricing crop insurance contracts 显示文摘 | Ozaki V A C (:win B K Shimta R | 2008 | Applied Economics2008，40，9： | 1 |
| 13 | Environmental study of the impact of greenery in an institutional campus in the tropics显示文摘 | Wong N H Jusuf S K Win A A L | 2007 | Building and Environment2007，，42： | 1 |
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