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| 1 | ob基因型对小鼠早期发育的影响显示文摘目的 探讨ob基因对早期发育的影响及其在发育早期的显性程度。方法 用聚合酶链反应和限制性内切酶法检测C5 7BL/ 6Job小鼠的 3种基因型 :野生型 (+ / + )、杂合体型 (ob/ + )及突变型 (ob/ob)。记录小鼠出生 4d~ 2个月的体重。比较出生后 7、14和 2 4d小鼠的腹股沟白色脂肪(WAT)和背肩岬的褐色脂肪 (BAT)湿重。结果 小鼠出生 2周后 ,ob/ob小鼠体重快速增长 ,7周时已是 + / +和ob/ +小鼠体重的 2倍 ;2 4d时的WAT明显高于 + / +和ob/ +小鼠。ob基因型对BAT的影响早于WAT。ob/ +小鼠的体重和WAT均介于 + / +小鼠和ob/ob小鼠之间。 2周以前 ,ob基因对体重影响的显性指数在 1 0~ 0 5之间 ,表现为共显性 ,6周时 ,显性指数接近 0 0 ,几乎为完全隐性。结论 ob基因型对体重和WAT的影响始于第 2周后 ; | 徐培渝 Truett GE Walker WA | 2000 | 中华预防医学杂志2000，34，6： | 2 |
| 2 | Pediatric obesity and vitamin D deficiency:a proteomic approach identifies muhimeric adiponectin as a key link between these conditions 显示文摘 | Walker GE Ricotti R Roccio M | 2014 | PLoS One2014，9，83： | 1 |
| 3 | Psychiatric distress amplifies symptoms after surgery for chronic rhinosinusitis显示文摘 | Davis GE Yueh B Walker E | 2005 | Otolaryngol Head Neck Surg2005，132，18： | 1 |
| 4 | Psychiatric distress amplifies symptoms after surgery for chronic rhinosinusitis 显示文摘 | Davis GE Yueh B Walker E | 2005 | Otolaryngol Head Neck Surg2005，132，2： | 1 |
| 5 | The status of platinumanticancer drugs in the clinic and in clinical trials 显示文摘 | Whealc NJt Walker S Craig GE | 2010 | DaltonTrans2010，39，35： | 1 |
| 6 | Misty (m) affects growth traits显示文摘 | Truett GE Tempelman RJ Walker JA | | 0，，： | 1 |
| 7 | Oral testosterone undecanoate in the management of delayed puberty in boys: pharmacokinetics and effects on sexual maturation and growth显示文摘 | Butler GE Sellar RE Walker RF | 1992 | J Clin Endocfinnl Metab1992，75，1： | 1 |
| 8 | Infected vertebmplasty: report of two cases and review of the literature显示文摘 | Walker DH Mummaneni P Rodts GE Jr | 2004 | Neumsurg Focus2004，17，6： | 1 |
| 9 | Sporadic mutations in melanocortin receptor 3 in morbid obese individuals 显示文摘 | Mencarelli M Walker GE Maestrini S | 2008 | Eur J Hum Genet2008，16，： | 1 |
| 10 | A fundamental limit on delay estimation using partially correlated speckh signals 显示文摘 | Walker WF Trahey GE | 1995 | IEEE Trans Ultrason Ferroelect Freq Contr1995，42，： | 1 |
| 11 | The status of plati- num anticancer drugs in the clinic and in clinical trials显示文摘 | WHEATE NJ WALKER S CRAIG GE | 2010 | Dal- ton T2010，39，35： | 1 |
| 12 | Obesity modifies expression profiles of metabolic markers in superficial and deep subcutaneous abdominal adipose tissue depots显示文摘 | Walker GE Marzullo P Prodam F | 2014 | Endocrine2014，46，1： | 1 |
| 13 | A library-based ecological st udy to investigate the contribution of ethnicity to the incidence of oralcancer within health authorities in England and Wales显示文摘 | Elled ge RO Khazaee Farid R Walker RJ | | 0，，1： | 1 |
| 14 | The status of plat- inum anticancer drugs in the clinic and in clinical trials 显示文摘 | Wheate N J Walker S Craig GE | 2010 | Dalton Trans2010，39，35： | 1 |
| 15 | Obesity modifies expression profiles of metabolic markers in superficial and deep subcutaneous ab- dominal adipose tissue depots 显示文摘 | Walker GE Marzulo P Prodam F | 2014 | Endocrine2014，46，1： | 1 |
| 16 | Pharmacokinetics,nephratoxicity andin vitroantibacterial activity associated with single versus multiple (three times) daily gentamicin treatments inhorses显示文摘 | Godber LM Walker RD Stein GE | 1995 | Am J Vet Res1995，56，： | 1 |
| 17 | Human DNA quantitation using Alu element based polymerase chain reaction显示文摘 | Walker JA Kilroy GE Xing J | 2003 | Anal Biochem2003，315，： | 1 |
| 18 | Subcutaneous abdominal adipose tissue subcompartments: Potential role in rosiglitazone effects显示文摘 | Walker GE Marzullo P Verti B | 2008 | Obesity2008，16，9： | 1 |
| 19 | Pharmacokinetics, nephrotoxicosis, and in vitro antibacterial activity associated with single versus multiple (three times) daily gentamicin treatments in horses 显示文摘 | Godber LM Walker RD Stein GE | 1995 | Am J Vet Res1995，56，5： | 1 |
| 20 | Comparison of the Etest and agar dilution for in vitro antimicrobial susceptibility testing of Campylobaeter显示文摘 | Ge B Bodieis S Walker RD | 2002 | J Antimicrob Chemother2002，50，4： | 1 |
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