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| 1 | 儿童重症监护中血糖控制与器官功能衰竭和病死率的关系显示文摘目的研究机械通气患几发生高血糖与器官功能衰竭的关系;介绍澳大利亚和新西兰PICU控制血糖的方法与实践。设计前瞻性队列研究。场所澳大利亚和新西兰的全部9家专业PICU病房。对象机械通气〉12h的患儿,但除外以下情况:合并糖尿病酮症酸中毒;家庭机械通气;入院时经积极心肺复苏;签有“不予复苏”医嘱。干预无。测量指标和主要结果所有患儿的血糖最长监测时间为14d,用临床和实验室指标计算儿童logistic器官功能障碍评分(PELOD)。研究中共有409例患儿使用了胰岛素。50%的患儿血糖值〉6.1mmol/L,同时89%患儿的血糖峰值〉6.1mmol/L,达到峰值的时间中位数是7h。在血糖-时间曲线上,采样时间中位数对应的曲线下面积〉6.1mmol/睹被定义为高血糖。高血糖患儿病死率为13%,而无高血糖者病死率为3%。高血糖和高PELOD(≥10)呈独立相关(OR值为3.41,95%CI:1.91~6.10)。高血糖与病死率也呈独立相关(OR值为3.31,95%CI:1.26~7.70)。早期高血糖(最初48h内)与上述预后亦相关,但与1d后PELOD加重和2d后PELOD≥10无关。5%的息儿接受了胰岛素治疗。结论高血糖在PICU较常见,通常出现较早,并与器官功能衰竭和死亡呈独立相关。但早期高血糖与晚发或加重的器官功能衰竭无关。澳大利亚和新西兰的PICU很少使用胰岛素。 | Yung M Wilkins B Slater A | 2008 | 中国小儿急救医学2008，15，2： | 8 |
| 2 | Percutaneous balloon dilatation of the mitral valve:an analysis of echocardiographic variables related to outcome and the mechanism of dilatiation显示文摘 | WILKINS G T WEYMAN A Z ABASCAL V M | 1988 | Br Heart J1988，60，4： | 2 |
| 3 | Medical student depression and its correlates across three international medical schools显示文摘BACKGROUND Medical students have high rates of depression, anxiety, and burnout that have been found to affect their empathy, professional behaviors, and performance as a physician. While studies have examined predictors for burnout and depression in the United States (US), no study, to our knowledge, has compared depression in medical students cross-culturally, or has attempted to examine the effect of factors influencing rates including burnout, exercise, stress, unmet mental health needs, and region. AIM To examine rates of depression in three international cohorts of medical students, and determine variables that may explain these differences. METHODS Convenience samples of medical students from three countries (US, China, and a Middle Eastern country whose name remains anonymous per request from the school) were surveyed in this observational study. Using the Patient Health Questionnaire-2 (PHQ-2) and a modified Maslach Burnout Inventory, depression and burnout were examined among medical students from the three cohorts (n = 473). Chi-square test and analysis of variance were used to examine differences in demographics, behavioral, and psychological variables across these three schools to identify potentially confounding descriptive characteristics. Analysis of covariance compared depression and the emotional exhaustion component of burnout identified through Principal Component Analysis across countries. Multiple linear regression was used to analyze the impact of demographic, behavioral, and psychological variables on screening positive for depression. RESULTS Medical students from the Middle Eastern country had the highest rates of positive depression screens (41.1%), defined as a PHQ-2 score of ≥ 3, followed by China (14.1 %), and then the US (3.8%). More students in the Middle Eastern school had unmet mental health needs (50.8%) than at the medical school in China (34.8%) or the school in the US (32.8%)(Pearson chi-square significance < 0.05). Thus, PHQ-2 scores were adjusted for unmet mental health needs;however, the Middle Eastern country continued to have the highest depression. Adjusting for PHQ-2 score, medical students from the US scored the highest on emotional exhaustion (a measure of burnout). Demographic variables did not significantly predict medical student depression;however, lack of exercise, unmet mental health needs, stress, and emotional exhaustion predicted nearly half of depression in these cohorts. In comparison to the US, coming from the Middle Eastern country and China predicted higher levels of depression. CONCLUSION Depression rates differ in three international cohorts of medical students. Measured factors contributed to some observed differences. Identifying sitespecific prevention and intervention strategies in medical student mental health is warranted. | Jessica A Gold Xinran Hu Gan Huang Wan-Zhen Li Yi-Fan Wu Shan Gao Zhe-Ning Liu Mickey Trockel Wan-Zhen Li Yi-Fan Wu Shan Gao Zhe-Ning Liu Robert M Rohrbaugh Kirsten M Wilkins | 2019 | World Journal of Psychiatry2019，9，4： | 2 |
| 4 | Sequencing of a Cultivated Diploid Cotton Genome-Gossypium arboreum显示文摘Sequencing the genomes of crop species and model systems contributes significantly to our understanding of the organization,structure and function of plant genomes.In a `white paper' published in 2007,the cotton community set forth a strategic plan for sequencing the AD genome of cultivated upland cotton that initially targets less complex diploid genomes.This strategy banks on the high | WILKINS Thea A | 2008 | 棉花学报2008，20，S1： | 2 |
| 5 | X-ray focusing using microchannel plates I theory显示文摘 | Chapman H N Nugent K A Wilkins S W | 1993 | Appl Opt1993，32，： | 2 |
| 6 | Carbon-fiber brushes for superconducting machines显示文摘 | McNab I R Wilkin G A | 1972 | Electronics and Power1972，18，1： | 2 |
| 7 | Three-year safety and efficacy of vicriviroc, a CCR5 antagonist, in HIV- 1-infected treatment-experienced patients显示文摘 | Wilkin TJ Su Z Krambrink A | 2010 | J Acquir Immune Defic Syndr2010，54，5： | 1 |
| 8 | 一般人群中发生心力衰竭的10年风险方程显示文摘目前急需能减轻心力衰竭负担的一级预防策略,但未见实用有效的风险预测工具。该研究旨在得出一个计算心力衰竭事件发生的10年风险方程。研究者根据7个社区队列,至少12年随访的个体水平数据,推导并验证了心力衰竭的种族和性别特异性10年风险方程。1985-2000年间招募年龄30~79岁在基线时无心血管病的研究对象,创建一个集合队列并随机分组以进行方程推导和内部验证。在另两个队列中也评估了该模型的性能。 | Khan SS Ning H Shah SJ Yancy CW Carnethon M Berry JD Mentz RJ O’Brien E Correa A Suthahar N de Boer RA Wilkins JT Lloyd-Jones DM 刘青 叶鹏 | 2019 | 中华高血压杂志2019，27，6： | 1 |
| 9 | Protein identification and analysis tools in the ExPASy server显示文摘 | Wilkins MR Gasteiger E Bairoch A Sanchez JC Williams KL Appel RD | 1999 | Methods Mol Biol1999，112，： | 1 |
| 10 | Use of an extended Kalman filter as a robust tyre force estimator 显示文摘 | WILKIN M A MANNING W J CROLLA D C | 2006 | Vehicle System Dynamics Supplement2006，44，1： | 1 |
| 11 | Levels of Expression of P-Selectin, E-Selectin, and Intercellular Adhesion Molecule-1 in Coronary Atherectomy Specimens from Patients With Stable and Unstable Angina Pectoris显示文摘 | Alan N Tenaglia MD Andrew J Buda MD Robert G Wilkins MD Michael K Barron MD Paul R Jeffords BS Khoa Vo BS Maureen O Jordan BS Barry A Kusnick MD David J Lefer PhD | 1997 | The American Journal of Cardiology1997，，6： | 1 |
| 12 | History of water- column anoxia in the Black Sea indicated by pyrite framboids size distributions显示文摘 | WILKIN R T ARTHUR M A DEAN W E | 1997 | Earth and Planetary Science Letters1997，148，34： | 1 |
| 13 | Efficient cultures:exploring the relationship between culture and organizational performance显示文摘 | Wilkins A L Ouchi W G | | 0，，： | 1 |
| 14 | A modified hot borate method significantly enhances the yield of high-quality RNA from cotton (Gossypium hirsutum L )显示文摘 | WAN C Y WILKINS T A | | 0，，01： | 1 |
| 15 | Contrast and resolution in imaging with a microfocus X-ray source显示文摘 | Pogany A Gao D Wilkins S W | 1997 | Reviezoof Scientific Instruments1997，68，： | 1 |
| 16 | Ventricular fibrillation, an ex- treme presentation of primary hyperaldosteronism显示文摘 | Abdo A Bebb RA Wilkins GE | 1999 | Can J Cardiol1999，15，3： | 1 |
| 17 | Protein identification and analysis tools on the ExPASy server显示文摘 | WILKINS M R GASTEIGER E BAIROCH A | 1999 | Methods Mol Biol1999，112，： | 1 |
| 18 | On Friction Braking Demand with Regenerative Braking显示文摘 | Walker A M Lamperth M U Wilkins S | 2002 | SAE2002，，： | 1 |
| 19 | Better Stories,Not Better Constructs,to Generate Better Theory:A Rejoinder to Eisenhardt显示文摘 | DYER G WILKINS A | 2001 | The Academy of Management Review2001，16，3： | 1 |
| 20 | Trace element and ∑DDT concentrations in horticultural soils from the Tasman,Waikato and Auckland regions of New Zealand显示文摘 | GAW S K WILKINS A L KIM N D | 2006 | Science of the Total Environment2006，，355： | 1 |
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