|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Electronic structure and optical properties of the Co-doped anatase TiO2 studied from first principles 显示文摘 | Weng H M Yang X P Dong J M | 2004 | Phys Rev2004，69，12： | 1 |
| 2 | Improved high Q value of MgTiO3-CaTiO3 microwave dielectric ceramics at low sintering temperature显示文摘 | Weng M H | 2001 | Materials Research Bulletin2001，36，： | 1 |
| 3 | Effects of additives on micro-structures and microwave dielectric properties of (Zr,Sn)TiO4 ceramics显示文摘 | Huang C L Weng M H Chen H L | 2001 | Mater Chem Phys2001，71，： | 1 |
| 4 | Effects of addtives on microstructure and microwave dielectric properties of (Zr,Sn) TiO4 ceramics显示文摘 | HUANG C L WENG M H CHEN H L | 2001 | Mater Chem Phys2001，71，： | 1 |
| 5 | Genetic variation of Zoysia as revealed by Random Amplified Polymorphic DNA ( RAPD) and Isozyme pattern 显示文摘 | Weng J H Fan M J Lin Y | 2007 | Planttion Science2007，10，： | 1 |
| 6 | Antiviral effect of epigallocatechin gallate on enterovirus 71显示文摘 | Ho H Y Cheng M L Weng S F | | 0，，14： | 1 |
| 7 | Assessment of tobacco heating system 2.4 on osteogenic differentiation of mesenchymal stem cells and primary human osteoblasts compared to conventional cigarettes显示文摘BACKGROUND Cigarette smoking(CS)is the most common method of consuming tobacco.Deleterious effects on bone integrity,increased incidence of fractures,and delayed fracture healing are all associated with CS.Over 150 of the 6500 molecular species contained in cigarette smoke and identified as toxic compounds are inhaled by CS and,via the bloodstream,reach the skeletal system.New technologies designed to develop a reduced-risk alternative for smokers are based on electronic nicotine delivery systems,such as e-cigarettes and tobacco heating systems(THS).THS are designed to heat tobacco instead of burning it,thereby reducing the levels of harmful toxic compounds released.AIM To examine the effects of THS on osteoprogenitor cell viability and function compared to conventional CS.METHODS Human immortalized mesenchymal stem cells(n=3)and primary human preosteoblasts isolated from cancellous bone samples from BG Unfall Klinik Tübingen(n=5)were osteogenically differentiated in vitro with aqueous extracts generated from either the THS 2.4“IQOS”or conventional“Marlboro”cigarettes for up to 21 d.Cell viability was analyzed using resazurin conversion assay(mitochondrial activity)and calcein-AM staining(esterase activity).Osteogenic differentiation and bone cell function were evaluated using alkaline phosphatase(AP)activity,while matrix formation was analyzed through alizarin red staining.Primary cilia structure was examined by acetylatedα-tubulin immunofluorescent staining.Free radical production was evaluated with 2’,7’-dichlorofluoresceindiacetate assay.RESULTS Our data clearly show that THS is significantly less toxic to bone cells than CS when analyzed by mitochondrial and esterase activity(P<0.001).No significant differences in cytotoxicity between the diverse flavors of THS were observed.Harmful effects from THS on bone cell function were observed only at very high,non-physiological concentrations.In contrast,extracts from conventional cigarettes significantly reduced the AP activity(by two-fold)and matrix mineralization(four-fold)at low concentrations.Additionally,morphologic analysis of primary cilia revealed no significant changes in the length of the organelle involved in osteogenesis of osteoprogenitor cells,nor in the number of ciliated cells following THS treatment.Assessment of free radical production demonstrated that THS induced significantly less oxidative stress than conventional CS in osteoprogenitor cells.CONCLUSIONTHS was significantly less harmful to osteoprogenitor cells during osteogenesisthan conventional CS. Additional studies are required to confirm whether THS isa better alternative for smokers to improve delays in bone healing followingfracture. | Romina H Aspera-Werz Sabrina Ehnert Monja Müller Sheng Zhu Tao Chen Weidong Weng Johann Jacoby Andreas K Nussler | 2020 | World Journal of Stem Cells2020，12，8： | 1 |
| 8 | An evaluation approach to engineering design in QFD processes using fuzzy goal programming models显示文摘 | CHEN L H WENG M C | 2006 | European Journal of Operational Research2006，172，1： | 1 |
| 9 | Lowering of sintering temperature and microwave dielectric properties of BaTi4O9 ceramics prepared by the polymeric precursor method显示文摘 | Weng M H Liang T J Huang C L | 2002 | J Eur Ceram Soc2002，22，： | 1 |
| 10 | Effects of additives on microstructures and microwave dielectric properties of(Zr,Sn)Ti O4ceramics显示文摘 | HUANG C L WENG M H CHEN H L | 2000 | Mater Chem And Phy2000，71，1： | 1 |
| 11 | Effects of creating an opening in existing beams 显示文摘 | MANSUR M A TAN K H WENG W | 2001 | ACI Structural Journal2001，98，3： | 1 |
| 12 | Novel quaternary ammonium ionic liquids and their use as dual solvent-catalysts in the hydrolytic reaction 显示文摘 | Weng J L Wang C M Li H R | 2006 | Green Chem2006，8，1： | 1 |
| 13 | Effect of thermal treatment on the electrical properties of the Sol-gel-derived (Zr, Sn)TiO4 thin films 显示文摘 | Yang R Y Kuan H Weng M H | 2009 | Ceramics International2009，35，1： | 1 |
| 14 | Estimating heat tolerance among plant species by two chlorophyll fluorescence parameters显示文摘 | Weng J H Lai M F | 2005 | Photosynthetica2005，43，3： | 1 |
| 15 | Determination of serum fibrosis indexes in patients with chronic and its significance显示文摘 | Zheng M Cai W Weng H | 2003 | Chin Med J(Engl)2003，116，3： | 1 |
| 16 | Effects of a frequent apolipoprotein E isoform, ApoE4Freiburg (Leu283Pro), on lipoproteins and the prevalence of coronary artery disease in whites显示文摘 | Orth M Weng W Funke H | 1999 | Arterioscler Thromb Vasc Biol1999，19，： | 1 |
| 17 | Synthesis and crystal structures of novel β-diketiminatolithium, iron, cobalt, nickel, zirconium complexes and their catalytical behaviors in polymerization of ethylene 显示文摘 | ZHOU M S HUANG S P WENG L H SUN W H LIU D S | 2003 | J Organometall Chem2003，665，12： | 1 |
| 18 | Effects of multiple airgaps on the thermal performance of firefighter protectiveclothing under low-level heat exposure 显示文摘 | FU M WENG W YUAN H | 2014 | TextileResearch Journal2014，84，9： | 1 |
| 19 | Syntheses and characerizations of two novel Ln(Ⅲ)-Cu(Ⅱ) coordination polymers constructed by pyridine-2,4-dicarboxylate ligand显示文摘 | Liang Y C Hong M C Sun D F Zhao Y J Weng J B Wang R H | | 0，，： | 1 |
| 20 | The draft genome of the fast-growing non-timber forest species moso bamboo (PhyUostachys heterocycla) 显示文摘 | Peng Z H Lu Y Li L Zhao Q Feng Q Gao Z M Lu H Y Hu T YAO N Liu K Y LiY FanDL GuoYL LiW J LuY Q Weng Q J Zhou C C Zhang L Huang T Zhu C R Liu X G Yang X W Wang T Miao K Zhuang C Y Cao X L Tang W L Liu G S Liu Y L Chen J Liu Z J Yuan L C Liu Z H Huang X H LuT T Fei B H Ning Z M Han B Jiang Z H | 2013 | Nature Genetics2013，45，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员