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| 1 | European cooperation to tackle the legacies of hexachlorocyclohexane(HCH)and lindane显示文摘Hexachlorocyclohexane(HCH)waste isomers from lindane production are the largest single POPs legacy,with an estimated 4.8 to 7.4 million tonnes of disposed waste.The largest part of this waste e 1.8 to 3 million tonnes e was disposed in Europe,where most producers were located.This paper provides a short overview of projects supported by the European Union(EU)to address this waste legacy and to implement the Stockholm Convention for this group of POPs with associated protection of soil,ecosystems and human health.We report here particularly on the results of a project financed by the EU called the“HCH in EU project”,which aimed to develop a systematic inventory of sites where HCH was handled and potentially resulted in contamination.The compiled information provide guidance for competent authorities to further assess their national HCH inventory and to further develop a strategy to address this large POP legacy in future.The systematic inventory revealed that there were at least 299 sites where HCH was handled.These sites include 54 former production sites,76 pesticide processing plants that used lindane,59 uncontrolled HCH waste isomer deposits,29 landfills with HCH waste,34 former or current storage sites for stocks of obsolete pesticides including technical HCH or lindane,and 16 HCH treatment or disposal sites.Additionally,at 31 of the sites lindane/technical HCH was used in applications with significant risk of soil pollution,such as wood treatment.The number of sites in this latter category is likely higher and will need further assessment.In addition to this inventory,the“HCH in EU project”produced detailed country reports,a guidance document for how to find potentially HCHimpacted sites,and a strategy document for implementing the sustainable management of these sites EU-wide,with proposed actions at the EU,country,and site level.Furthermore,the project has facilitated information exchange and e together with other related EU projects e has led to sharing information and best practices among member states and to establishing a network of authorities and other stakeholders working on the lindane/HCH waste legacy.This collaboration will facilitate a more systematic and better coordinated process to further assess,secure,and remediate the large HCH waste legacy and reduce and control lindane/HCH releases in the EU and possibly beyond.Such a coordinated effort and exchange of information for inventorying and managing contaminated sites might also be useful for other POPs such as PFOS/PFOA or dioxins. | John Vijgen Boudewijn Fokke Guido van de Coterlet Katja Amstaetter Javier Sancho Carlo Bensaïah Roland Weber | 2022 | Emerging Contaminants2022，8，1： | 4 |
| 2 | Mechanical measurement of the residual stress in thin PVD films显示文摘 | Vijgen R Dautzenberg | 1995 | Thin Solid Films1995，270，： | 1 |
| 3 | la/lb subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus显示文摘 | Nyanguile O Devogelaere B Vijgen L Van den Broeck W Pauwels F Cummings M D De Bondt H | | 0，，06： | 1 |
| 4 | Efficacy of re -treat- ment with TMCA35 as combination therapy in hepatitis C vi- rus - infected patients following TMC435 monotherapy 显示文摘 | LENZ O BRUIJNE J VIJGEN L | 2012 | Gastroentorology2012，143，5： | 1 |
| 5 | Sheared Wing- Tip Aerodyna- mics:Wind- Tunnel and Computational Investigation 显示文摘 | P M H W Vijgen | 1986 | AIAA1986，26，3： | 1 |
| 6 | Efficacy of Re-treatment With TMC435 as Combination Therapy in Hepatitis C Virus–Infected Patients Following TMC435 Monotherapy显示文摘 | Oliver Lenz Joep de Bruijne Leen Vijgen Thierry Verbinnen Christine Weegink Herwig Van Marck Ina Vandenbroucke Monika Peeters Kenneth Simmen Greg Fanning Rene Verloes Gaston Picchio Hendrik Reesink | 2012 | Gastroenterology2012，，5： | 1 |
| 7 | Hexachlorocyclohexane (HCH) as new Stockholm Convention POPs-a global perspective on the management of lindane and its waste isomers显示文摘 | VIJGEN J ABHILASH P C LI Y | 2011 | Environmental Science and Pollution Research2011，18，2： | 1 |
| 8 | Inhibition of feline (FIPV) and human (SARS) coronavirus by semisynthetic derivatives of glycopeptide antibiotics显示文摘 | Balzarini J Keyaerts E Vijgen L | 2006 | Antiviral Research2006，72，1： | 1 |
| 9 | Stockholm Convention POPs-a global perspective on the management of lindane and its waste isomers 显示文摘 | Vijgen J Abhilash P C Hexachlorocyclohexane ( HCH ) Li Y F as new | 2011 | Environ Sci Pollut Res Int2011，18，2： | 1 |
| 10 | Inci- sional hernias in temporary stoma wounds: a cohort study显示文摘 | Schreinemacher MH Vijgen GH Dagnelie PC | 2011 | Arch Surg2011，14，146： | 1 |
| 11 | A novel pancorona-virus RT-PCR assay: frequent detection of human coronavirusNL63 in children hospitalized with respiratory tract infections inBelgium显示文摘 | Elien Moes Leen vijgen Els keyaerts | 2005 | BMC infectious diseases2005，5，： | 1 |
| 12 | Inhibition of feline (FIPV) and human (SARS) coronavirus by semisynthetic derivatives of glycopeptide antibiotics 显示文摘 | Balzarini J Keyaerts E Vijgen L | 2006 | Antiviral Res2006，72，1： | 1 |
| 13 | Induction of labour versus expectant monitoring for gestational hypertension or mild pre-eclampsia after 36 weeks’ gestation (HYPITAT): a multicentre, open-label randomised controlled trial显示文摘 | Corine M Koopmans Denise Bijlenga Henk Groen Sylvia MC Vijgen Jan G Aarnoudse Dick J Bekedam Paul P van den Berg Karin de Boer Jan M Burggraaff Kitty WM Bloemenkamp Addy P Drogtrop Arie Franx Christianne JM de Groot Anjoke JM Huisjes Anneke Kwee Aren J va | 2009 | The Lancet2009，，9694： | 1 |
| 14 | A novel pancoronavirus RT-PCR assay: frequent detection of human coronavirus NL63 in children hospitalized with respiratory tract infections in Belgium显示文摘 | Moes E Vijgen L Keyaerts E | 2005 | BMC Infect Dis2005，5，1： | 1 |
| 15 | Development of one-step,real-time,quantitative reverse transcriptase PCR assays for absolute quantitation of human coronaviruses OC43 and 229E显示文摘 | Vijgen L Keyaerts E Mo e¨s E | 2005 | J Clin Microbiol2005，43，11： | 1 |
| 16 | Haemostatic effectsin vivo after snakebite by the red-necked keelback(Rhabdophissubminiatus)显示文摘 | Hoffmann J J Vijgen M Smeets R E | | Blo0，，： | 1 |
| 17 | Mechanical measurement of the residual stress in thin PVD films显示文摘 | VIJGEN R O E DAUTZENBERG J H | 1995 | Thin Solid Films1995，270，： | 1 |
| 18 | Cost-effectiveness analyses of health promotion programs : A case study of smoking prevention and cessation among Dutch students 显示文摘 | VIJGEN SM VANBAAL PH HOOGENVEEN RT | 2008 | Health Educ Res2008，23，2： | 1 |
| 19 | A novel pancoronavirus RT-PCR assay:frequent detection of human coronavirus NL63in children hospitalized with respiratory tract infections in Belgium显示文摘 | Mos E Vijgen L Keyaerts E Pyrc K Berkhout B Van R M | 2005 | BMC Infect Dis2005，5，： | 1 |
| 20 | Identification of six new polymorphisms in the human coronavirus 229E receptor gene (aminopeptidase N/CD13)显示文摘 | Vijgen L Keyaerts E Zlateva K | 2004 | Int J Infect Dis2004，8，4： | 1 |
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