|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Diabetic cardiomyopathy:Pathophysiology,diagnostic evaluation and management显示文摘Diabetes affects every organ in the body and cardiovascular disease accounts for two-thirds of the mortality in the diabetic population.Diabetes-related heart disease occurs in the form of coronary artery disease(CAD),cardiac autonomic neuropathy or diabetic cardiomyopathy(DbCM).The prevalence of cardiac failure is high in the diabetic population and DbCM is a common but underestimated cause of heart failure in diabetes.The pathogenesis of diabetic cardiomyopathy is yet to be clearly defined.Hyperglycemia,dyslipidemia and inflammation are thought to play key roles in the generation of reactive oxygen or nitrogen species which are in turn implicated.The myocardial interstitium undergoes alterations resulting in abnormal contractile function noted in DbCM.In the early stages of the disease diastolic dysfunction is the only abnormality,but systolic dysfunction supervenes in the later stages with impaired left ventricular ejection fraction.Transmitral Doppler echocardiography is usually used to assess diastolic dysfunction,but tissue Doppler Imaging and Cardiac Magnetic Resonance Imaging are being increasingly used recently for early detection of DbCM.The management of DbCM involves improvement in lifestyle,control of glucose and lipid abnormalities,and treatment of hypertension and CAD,if present.The role of vasoactive drugs and antioxidants is being explored.This review discusses the pathophysiology,diagnostic evaluation and management options of DbCM. | Joseph M Pappachan George I Varughese Rajagopalan Sriraman Ganesan Arunagirinathan | 2013 | World Journal of Diabetes2013，4，5： | 57 |
| 2 | Antibiotic - asso- ciated diarrhea: a refresher on causes and possible prevention with probiotics - -continuing education article 显示文摘 | Varughese C A Vakil N H Phillips K M | 2013 | J Pharm Pract2013，26，5： | 1 |
| 3 | Permissive hypercapnia in neonates :The case of the good the bad ,and the ugly显示文摘 | Varughese M Patole S Shama A | 2002 | Pediatr Pulmonol2002，33，1： | 1 |
| 4 | Molecular dynamics studies on troponin (TnI-TnT-TnC) complexes:insight into the regulation of muscle contraction显示文摘 | Varughese J F Chalovich J M Li Y | 2010 | J Biomol Struct Dyn2010，28，2： | 1 |
| 5 | Effects of hyperoxia on tumor necrosis factor alpha and Gro beta expression in newborn rabbit lungs 显示文摘 | Varughese R Nayak JL LoMonaco M | 2003 | Lung2003，181，6： | 1 |
| 6 | Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine 显示文摘 | GUNTER J B VARUGHESE A M HARRINGTON J F | 1995 | Anesth Analg1995，81，6： | 1 |
| 7 | Permissive hypercapnia in neonates : the case of the good, the bad, and the ugly 显示文摘 | Varughese M Patole S Shama A | | Ped-0，，： | 1 |
| 8 | Estimating nuclear waste production in India显示文摘 | Ramana M V Thomas D G Varughese S | 2001 | Current Science2001，81，： | 1 |
| 9 | Plasmacytoid (CD68+ CD123+) monocytes may play a crucial role in the pathogenesis of hydroa vacciniforme:a case report显示文摘 | Varughese N Petrella T Singer M | | 0，，08： | 1 |
| 10 | Percutaneous continuous ambulatory peritoneal dialysis (CAPD) catheter insertion--a preferred option for developing countries显示文摘 | Varughese S Sundaram M Basu G | 2010 | Trop Doct2010，40，2： | 1 |
| 11 | A family of min-chain polymeric lewis acids:synthesis and fluorescent sensing properties of boron-modified polythiophene显示文摘 | Sundararaman A Victor M Varughese R | 2005 | J Am Chem Soc2005，127，13： | 1 |
| 12 | Permis- sive hy-percapnia in neonates : the ease of the good, the bad, and the ugly 显示文摘 | VARUGHESE M PATOLE S SHAMA A | 2006 | Pediatr Pulmonol2006，33，1： | 1 |
| 13 | Permissive hypercapnia in neonates:the case of the good,the bad,and the ugly显示文摘 | Patole S Shama A Whitehall J | 2002 | Pediatr Pulmonol2002，33，1： | 1 |
| 14 | Risk awareness on uterine cancer among Australian women显示文摘 | GEOEGE M ASAB N A VARUGHESE E | 2014 | Asian Pac J Can- cer Prev2014，15，10： | 1 |
| 15 | Factors pre dictive of poor behavioral compliance during inhaled in duction in children显示文摘 | Varughese A M Nick T G Gunter J | 2008 | Anesth Analg2008，107，41： | 1 |
| 16 | A novel three-dimensional polymeric structure of crystalline neodymium malonate hydrate显示文摘 | Doreswamy B H Mahendra M Sridhar M A Sasidharaprasad J Varughese P A George J Varghese G | | 0，，10： | 1 |
| 17 | Thrombotic microangiopathy following docetaxel and trastuzumab chemotherapy: a case report 显示文摘 | Siau K Varughese M | 2010 | Med Oncol2010，27，4： | 1 |
| 18 | Antibiotic-associateddiarrhea: a refresher on causes and possible prevention with probiotics-continuing education article显示文摘 | Varughese C A Vakil N H Phillips K M | 2013 | J Pharm Pract2013，26，5： | 1 |
| 19 | Twenty two years of tillage and mulching impacts on soil physical characteristics and carbon sequestration in Central Ohio显示文摘 | Kahlon M S Lal R Varughese M A | 2013 | Soil & Tillage Research2013，126，： | 1 |
| 20 | Effect of chemical modification on properties of hybrid fiber biocomposites显示文摘 | M J John B FranciS K T Varughese | 2008 | Compos (Part A) Appl S2008，39，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员