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| 1 | Colonoscopy for screening and follow up of patients with a family history of colorectal cancer显示文摘 | M. G.Tytherleigh V. V.Ng L. O.Mathew T.Banerjee K. V.Menon A. S.Mee R.Farouk | 2008 | Colorectal Disease2008，，5： | 1 |
| 2 | Epidemiological study of hypertensive retinopathy in the primary care setting: Retrospective cross-sectional review of retinal photographs显示文摘Objective:The objective is to estimate the prevalence and grading of hypertensive retinopa-thy in the primary care setting;examine the patient characteristics associated with hypertensive retinopathy;and examine the association of hypertensive retinopathy and other hypertension complications.Methods:This is a retrospective cross-sectional study.Subjects included adult hypertensive patients with available and gradable retinal photographs.Results:Two hundred fifty-six male hypertensive patients(34.3%)and 491 female hyper-tensive patients(65.7%)were included.The average duration of hypertension was 7.2 years,and 49.8%and 41.2%of patients were taking one or two antihypertensive medications respectively.Among 1491 qualified retinal photographs(744 right eye and 747 left eye),24.9%,62.6%,and 12.5%were classified as showing normal,mild,and moderate hypertensive retinopathy respec-tively.The three commonest retinal signs were generalized or focal arteriolar narrowing(650 cases,43.6%),hard exudates(168 cases,11.3%),and opacity(copper or silver wiring)of the arteriolar wall(166 cases,11.1%).Patients older than 61 years,having hypertension for more than 15 years,or taking three or more antihypertensive medications were significantly associated with hyperten-sive retinopathy(P<0.05).Conclusion:In a primary care clinic in Hong Kong,77.1%of hypertensive patients had hypertensive retinopathy.Advanced hypertensive retinopathy was the commonest target organ damage for hypertensive patients in a primary care clinic. | Lap-kin Chiang Michael K.C.Yau Cheuk-wai Kam Lorna V.Ng Benny C.Y.Zee | 2016 | Family Medicine and Community Health2016，4，4： | 0 |
| 3 | 在肺结核诊断中应用系列痰涂片的结果:系统综述显示文摘目前的国际结核病(TB)指南推荐在对肺结核可疑患者评价时应用3次痰涂片镜检以寻找结核菌。我们对符合3次痰标本结果标准的研究进行了系统的评价。通过对多个数据库和资源的检索,我们确定了共37个合格的研究。第3份标本中涂阳结果的增加(所有培阳病例作为分母的研究)和敏感性的增高(所有培阳病例作为分母的研究)是我们关注的主要结果。虽然各研究的方法和结果不同对数据综合构成了挑战,但亚组的分析提示对第3份标本的检查使结果和/或敏感性平均增加了2%~ 5%。把推荐的标本检查数量从3份减至2份(特别是在同一天收集的2份标本)对结核控制项目有利。有很多理由可潜在增加病例检出;许多实施性研究问题需要强调。如果按照国际间协调和标准化的方法,在痰标本镜检时应用现行技术检验哪种方法最有效,这样的研究会是最有用的,既可以增加本国的数据,又可进行研究之间的对比。 | S.R.Mase A.Ramsay V.Ng M.Henry P.C.Hopewell J.Cunningham R.Urbanczik M.D.Perkins M.A.Aziz M.Pai 张宗德 张立兴 | 2007 | 国际结核病与肺部疾病杂志2007，2，3： | 0 |
| 4 | Overnight pulse oximetry for screening of obstructive sleep apnea in at-risk adult patients in the primary care setting:prospective case series显示文摘Objective:To estimate prevalence of OSA among at risk adult patients in primary care setting.To test the correlation and agreement between overnight pulse oximetry and polysomnography(PSG).To test the OSA screening performance of overnight pulse oximetry.Design and Setting:Prospective case series involving adult Chinese patients with risk fac-tors for OSA at a primary care clinic of Hong Kong.Methods:The prevalence and severity of OSA were established based on overnight pulse oximetry derived oxygen desaturation index(ODI).Screening performance of overnight pulse oxi-metry was compared directly with gold standard diagnostic test PSG.Results:Three hundred and five male and 229 female patients were recruited.Snoring(48.3%)was the top presenting symptom.Three hundred and twenty five patients(60.9%)were screened positive to have OSA.One hundred and nine patients had performed PSG,the ODI_4 and apnoea-hypopnea index(AHI)had Pearson correlation coefficient 0.71(P<0.001).Bland and Alt-man plot showed good agreement.Using designation criteria of ODI_4≥5 events/hr,the sensitivity and specificity for OSA diagnosis are 94.4%and 78.9%respectively.Conclusion:The prevalence of OSA is 60.9% among adult primary care population who are at risk for OSA.Overnight pulse oximetry shows good performance as a screening tool for the screening of OSA. | Lap-Kin Chiang Cheuk-Wai Kam Lorna V.Ng | 2017 | Family Medicine and Community Health2017，5，3： | 0 |
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