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26篇 您的检索式:作者名="Ulrich AB"
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1Interferon-γ inhibits ghrelin expression and secretion via a somatostatin-mediated mechanism显示文摘AIM:To investigate if and how the proinflammatory cytokine interferon γ(IFNγ) affects ghrelin expression in mice.METHODS:The plasma concentration of ghrelin,andgastric ghrelin and somatostatin expression,were examined in wild-type mice and mice infected with Helicobacter pylori(H.pylori).Furthermore,ghrelin expression was examined in two achlorhydric mouse models with varying degrees of gastritis due to bacterial overgrowth.To study the effect of IFNγ alone,mice were given a subcutaneous infusion of IFNγ for 7 d.Finally,the influence of IFNγ and somatostatin on the ghrelin promoter was characterized.RESULTS:H.pylori infection was associated with a 50% reduction in ghrelin expression and plasma concentration.Suppression of ghrelin expression was inversely correlated with gastric inflammation in achlorhdyric mouse models.Subcutaneous infusion of IFNγ suppressed fundic ghrelin mRNA expression and plasma ghrelin concentrations.Finally,we showed that the ghrelin promoter operates under the control of somatostatin but not under that of IFNγ.CONCLUSION:Gastric infection and inflammation is associated with increased IFNγ expression and reduced ghrelin expression.IFNγ does not directly control ghrelin expression but inhibits it indirectly via somatostatin.Jesper AB Strickertsson Kristina BV DΦssing Anna JM Aabakke Hans-Olof Nilsson Thomas VO Hansen Ulrich Knigge Andreas Kjr Torkel Wadstrm Lennart Friis-Hansen 2011World Journal of Gastroenterology2011,17,26:2
2Identification and sequeneing of the Syrian Golden hamster(Mesocricetusauratus) p16(INK4a) and p15 (INK4b) cDNA sand theirhomozy- gous gene delection in cheek pouch and pancreatic tumor cells 显示文摘Muscarella P Knobloch TJ Ulrich AB 2001Gene2001,278,12:1
3Surgery for locally re- current rectal cancer in the era of total mesorectal excision: is there still a chance for cure? 显示文摘Rahbari NN Ulrich AB Bruckner T 2011Ann Surg2011,253,3:1
4MUC4 mucin ex- pression in human pancreatic tumours is affected by organenvir- onment the possible role of TGF beta2显示文摘Choudhury A Moniaux N Ulrich AB 2004Br J Cancer2004,90,3:1
5Diverting stoma after low anterior resection:more arguments in favor显示文摘Ulrich AB Seiler C Rahbari N 0,,03:1
6Identification and sequencing of the Syrian Golden hamster (Mesocricetus auratus) p16 ( INK4a ) and p15(INK4b) cDNAs and their homozygous gene deletion in cheek pouch and pancreatic tumor cells显示文摘Muscarella P Knobloch TJ Ulrich AB 2001Gene2001,278,12:1
7Identification and sequencing of the Syrian Golden hamster (Mesocricetus auratus)p16(INK4a)and p15(INK4b)cDNAs and their homozygous gene delection in cheek pouch and pancreatic tumor cells显示文摘Muscarella P Knobloch TJ Ulrich AB 2001Gene2001,278,12:1
8Immortalization with telomerase of the Nestin-positive cells of the human pancreas 显示文摘Lee KM Nguyen C Ulrich AB 2003Biochem Biophys Res Commun2003,301,:1
9Diverting stoma after low anterior resection: more arguments in favor显示文摘Ulrich AB Seiler C Rahbari N 2009Dis Colon Rectum2009,52,3:1
10Absent umbilical artery end-diastolic velocity in growth-restricted fetuses: A risk factor for neonatal thrombocytopenia 显示文摘Ahmet AB Ulrich G Irwin R 2000Obstet Gynecol2000,96,:1
11Diverting stoma after low anterior resection: more arguments in favor显示文摘Ulrich AB Seiler C Hahbari N 11 al 2009Dis Colon Rt-f-hun2009,52,3:1
12Identification and sequencing of the Syrian Golden hamster (Mesooricetus auratus)p16(INK4a) and p15(INK4b) cDNAs and their homozygous gene deletion in cheek pouch and pancreatic tumor cells显示文摘Muscarella P Knobloch TJ Ulrich AB 2001Gene2001,,12:1
13Diverting stoma after low anterior resection:more arguments in favor显示文摘Ulrich AB Seiler C Rahbari N 0,,03:1
14Diverting stoma after low anterior resection:more arguments in favor显示文摘Ulrich AB Seiler C Rahbari N 2009Dis Colon Rectum2009,52,3:1
15Surgery for locally recurrent rectal cancer in the era of total mesorectal excision:is there still a chance for cure显示文摘Rahbari NN Ulrich AB Bruckner T 0,,03:1
16MUC4 mucin expression in human pancreatic tumours is affected by organ environment:the possible role of TGFbeta2 显示文摘Choudhury A Moniaux N Ulrich AB 2004Br J Cancer2004,90,3:1
17Early results from arandomized clinical trial of colon J pouch versus transversecoloplasty pouch after low anterior resection for rectal cancer显示文摘Ulrich AB Seiler CM Zegraggen K 2008Br Surg2008,95,10:1
18Early results from a randomized clinical trial of colon J pouch versus transverse coloplasty pouch after low anterior resection for rectal cancer显示文摘Ulrich AB Seiler CM Z'graggen K 2008Br J Surg2008,95,10:1
19Early results from a randomized clinical trial of colon J pouch versus trans- verse coloplasty pouch after low anterior resection for rectal cancer显示文摘Ulrich AB Seiler CM Z'Graggen K 2008Br J Surg2008,95,10:1
20Early results from a randomized clinical trial of colon J pouch versus transverse coloplasty pouch after low anterior resectionfor rectal cancer显示文摘Ulrich AB Seiler CM Graggen KZ 2008British Journal of Surgery2008,95,10:1
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