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1Prevalence of Helicobacter pylori infection and atrophic gastritis in patients with dyspeptic symptoms in Myanmar显示文摘AIM: To survey the detailed analyses for Helicobacter pylori(H. pylori) infection and gastric mucosal status in Myanmar.METHODS: A total of 252 volunteers with dyspeptic symptoms(155 female and 97 male; mean age of 43.6 ± 14.2 years) was participated in Yangon and Mandalay. The status of H. pylori infection was determined based on 5 different tests including rapid urease test, culture, histology, immunohistochemistry and serology. Histological scores were evaluated according to the update Sydney system and the Operative Link for Gastritis Assessment system. Pepsinogen(PG)Ⅰand PG Ⅱ were measured using enzyme-linked immunosorbent assays.RESULTS: The overall prevalence of H. pylori infectionwas 48.0%. There was no relationship between age and infection rate. Even in young group(less than 29 years old), the H. pylori infection rate was relatively high(41.9%). The prevalence of H. pylori infection was significantly higher in Yangon than that of Mandalay. H. pylori infection was significantly associated with the presence of gastric mucosal atrophy. All 7 subjects with peptic ulcer were infected with H. pylori. Although H. pylori-positive subjects showed stronger gastritis than H. pylori-negative subjects, most cases had mild gastritis.CONCLUSION: We revealed the prevalence of H. pylori infection in patients with dyspeptic symptoms in Myanmar. The H. pylori infection was a risk factor for peptic ulcer and stronger gastritis.Thein Myint Seiji Shiota Ratha-korn Vilaichone New Ni Than Than Aye Miyuki Matsuda Trang Thi Huyen Tran Tomohisa Uchida Varocha Mahachai Yoshio Yamaoka 2015World Journal of Gastroenterology2015,21,2:10
2p53 protein overexpression in low grade dysplasia (LGD) in barrett’s esophagus: Immunohistochemical marker predictive of progression显示文摘Allan P Weston Sushanta K Banerjee Prateek Sharma Trang M Tran Robert Richards Rachel Cherian 2001The American Journal of Gastroenterology2001,,5:2
3Anti-inflammatory effects of alkaloid enriched extract from roots of Eurycoma longifolia Jack显示文摘Objective: To examine the in vitro and in vivo anti-inflammatory effects of the alkaloid enriched extract(ELA) from the roots of Eurycoma longifolia. Methods: The in vitro antiinflammatory effects of ELA were evaluated by examining its inhibitory activities against nitric oxide(NO) production and inducible nitric oxide synthase(iN OS) and cyclooxygenase2(COX-2) expressions in lipopolysaccharide(LPS)-stimulated RAW264.7 cells. The level of NO produced in the culture media was determined by Griess method. The i NOS and COX-2 protein expressions were analyzed by Western blot. The in vivo effect of ELA was evaluated on LPS-induced septic shock in mice model. Mice mortality was monitored for5 days after injection of LPS. The chemical contents of the ELA were determined by using various chromatographic and spectroscopic techniques. Results: The ELA was found to exhibit a significant anti-inflammatory effect in both in vitro and in vivo models. The results demonstrated that ELA dose-dependently inhibited LPS-induced NO production as well as the protein iN OS and COX-2 expressions. In the septic shock model, ELA dose-dependently protected mice from LPS-induced mortality. Further study on the isolated components of ELA indicated that 9,10-dimethoxycanthin-6-one may contribute significantly to the antiinflammatory effects of the extract. Conclusions: These results suggest that ELA exhibits the anti-inflammatory activity via suppression of pro-inflammatory mediators such as NO, iN OS,and COX-2 and protects mice from LPS-induced mortality in septic shock model.Dao Thi Thanh Hien Tran Phi Long Tran Phuong Thao Jeong-Hyung Lee Duong Thu Trang Nguyen Thi Thu Minh Pham Van Cuong Do Thi Ngoc Lan Nguyen Hai Dang Nguyen Tien Dat 2019Asian Pacific Journal of Tropical Biomedicine2019,9,1:1
4Pathogenesis of Helicobacter pylori Infection显示文摘Dionyssios N. Sgouras Tran Thi Huyen Trang Yoshio Yamaoka 2015Helicobacter2015,,:1
5Prevalence, Risk Factors, and Disease Knowledge of Chronic Hepatitis B Infection in Vietnamese Americans in California显示文摘Nghi B. Ha Huy N. Trinh Trang T. Nguyen Truong-Sinh Leduc Christopher Bui Nghiem B. Ha Carrie R. Wong Anh Thu Tran Mindie H. Nguyen 2013Journal of Cancer Education2013,,2:1
6Novel CagA ELISA exhibits enhanced sensitivity of Helicobacter pylori CagA antibody显示文摘AIM To develop a novel Helicobacter pylori(H.pylori)CagA antibody enzyme-linked immunosorbent assay(ELISA)suitable for detecting serum anti-CagA antibodies with high sensitivity.METHODS Recombinant East Asian-type CagA protein was purified and immobilized for ELISA.Serum samples from 217Vietnamese individuals(110 H.pylori-infected and107 uninfected individuals)were applied.Conventional ELISA from Western-type CagA and our East Asian-type CagA ELISA were evaluated by comparing 38 subjects with the Western-type genotype and 72 subjects with the East Asian-type cagA genotype.Histological scores of the gastric mucosa were determined using the updated Sydney System to examine the relationship with anti-CagA antibody titers.RESULTS Recombinant 70-100 k Da fragments were immobilized on the ELISA plate.In ROC analysis,the area under the curve of our East Asian-type CagA ELISA was comparable to that of conventional CagA ELISA.The sensitivity of the two ELISAs differed depending on the cagA genotype.The sensitivity of East Asian-type Cag A ELISA was higher for subjects infected with East Asiantype cagA H.pylori(P<0.001),and the sensitivity of the conventional CagA ELISA tended to be higher for subjects infected with Western cagA H.pylori(P=0.056).The titer of anti-CagA antibody tended to correlate with monocyte infiltration scores(r=0.25,P=0.058)and was inversely correlated with H.pylori density(r=-0.26,P=0.043).CONCLUSION The novel ELISA is useful to detect anti-CagA antibodies in East Asian countries,and the titer may be a marker for predicting chronic gastritis.Yuichi Matsuo Yasutoshi Kido Junko Akada Seiji Shiota Tran Thanh Binh Tran Thi Huyen Trang Ho DQ Dung Pham Huu Tung Tran Dinh Tri Ngo P Minh Thuan Le Quang Tam Bui Chi Nam Vu Van Khien Yoshio Yamaoka 2017World Journal of Gastroenterology2017,23,1:1
7Preparation and characterization of graphene composites with conducting polymers显示文摘Trang L K H Tran T T Tae Y K 0,,01:1
8Compensation of Zn substitution and secondary phase controls effective mass and weighted mobility in In and Ga co-doped ZnO material显示文摘Conductivity s and thermal conductivity k are directly related to carrier concentration while Seebeck coefficient S is inversely proportional to carrier concentration.Therefore,improving thermoelectric(TE)performance is challenging.Here,the first-time analysis of secondary phase-controlled TE performance in terms of density-of-state effective mass m*d,weighted mobility mw and quality factor B is discussed in ZnO system.The results show that the secondary spinel phase Ga2O_(3)(ZnO)9 not only impacts on k but also on s and S at high temperature,while the effect of carrier concentration seem to be dominant at low temperature.For the high-spinel-segregation sample,a compensation of dopant atoms from the spinel to substitutional sites in the ZnO matrix at high temperature leads to a low decreased rate of temperaturedependent m*d.The compensation process also induces a band sharpening,a small mw reduction,and a large B enhancement.As a result,In and Ga co-doped ZnO bulk with the highest spinel segregation achieves the greatest PF improvement by 112.8%,owing to enhanced Seebeck coefficient by 110%as compared to the good Zn-substitution sample.Oanh Kieu Truong Le Anh Tuan Thanh Pham Ngoc Kim Pham Trang Huyen Cao Pham Truong Huu Nguyen Dung Van Hoang Hanh Kieu Thi Ta Dai Cao Truong Hoa Thi Lai Thuy Dieu Thi Ung Vinh Cao Tran Thang Bach Phan 2021Journal of Materiomics2021,7,4:0
9Influence of Input Factors on Surface Roughness and Material Removal Speed when Wire-EDM a Hardened SKD11 Steel Curve Profile显示文摘The goal of this research is to identify the best set of process machining parameters for wire-EDM(Electrical Discharge Machining)cutting of hardened SKD11 steel when machining a curve profile.The multi-objective function includes reducing surface roughness and increasing MRR(Material Removal Rate).The optimization process is prepared by using Taguchi method coupled Grey Relational Analysis.The obtained results revealed that Toff has the greatest influence on the average grey value(48.30%),followed by the influence of WF(Wire Feed,15.99%),VM(Cutting Voltage,9.33%),SV(Server Voltage,5.05%),Ton(Pulse on Time,1.81%),while SPD(Cutting Speed)has a negligible effect(0.89%).Moreover,using the optimal set of machining parameters generates in surface roughness of 1.25399mm and MRR of 26.5562 mm^(2)/min.The verification experiment and Anderson-Darling method demonstrate the validity of the proposed model,which can be utilized for estimating surface roughness and MRR.Tran Quoc Hung Nguyen Van Trang 2023Journal of Environmental Science and Engineering(B)2023,12,5:0
10A comparative analysis of weight-based machine learning methods for landslide susceptibility mapping in Ha Giang area显示文摘Landslide susceptibility maps (LSMs) are very crucial for planningpolicies in hazardous areas. However, the accuracy and reliability ofLSMs depend on available data and the selection of suitable methods.This study is conducted to produce LSMs by combinations of machinelearning methods and weighting techniques for Ha Giang province,Vietnam, where has limited data. In study area, we gather 11 landslideconditioning factors and establish a landslide inventory map.Computing the weights of classes (or factors) is very important toprepare data for machine learning methods to generate LSMs. Wefrst use frequency ratio (FR) and analytic hierarchy process (AHP)techniques to generate the weights. Then, random forest (RF), supportvector machine (SVM), logistic regression (LR), and AHP methods arecombined with FR and AHP weights to yield accurate and reliableLSMs. Finally, the performance of these methods is evaluated by fivestatistical metrics, ROC and R-index. The empirical results have shownthat RF is the best method in terms of R-index and the five metrics, i.e.TP rate (0.9661), FP rate (0.0), ACC (0.9835), MAE (0.0046), and RMSE(0.0350) for this study area. This study opens the perspective of weightbasedmachine learning methods for landslide susceptibility mapping.Thanh Trinh Binh Thanh Luu Trang Ha Thi Le Duong Huy Nguyen Trong Van Tran Thi Hai Van Nguyen Khanh Quoc Nguyen Lien Thi Nguyen 2023Big Earth Data2023,7,4:0
11Surveillance of dengue and chikungunya infection in Dong Thap,Vietnam:A 13-month study显示文摘Objective:To establish a surveillance in Dong Thap,at the border with Cambodia by assessing the presence of DHNV serotypes and CHIKV among patients hospitalized at Dong Thap general hospital.Methods:Cross-sectional descriptive analysis was conducted on a cohort of 131 patients hospitalized with acute fever and symptoms compatible with dengue or chikungunya.The study was conducted from January 2012 to February 2013.The full clinical picture was established as well as serological and molecular detection.Serological analysis was sequentially performed on blood samples collected on admission and an average of seven days after admission.The detection of IgM antibody to DENV was performed by IgM capture ELTSA and the detection of DENV and CHIKV RNA was done by reverse-transcription multiplex PCR.Results:101 patients out of 131(77%) were confirmed with dengue.All four dengue serotypes were detected with a predominance of DENV2 and DENV4.No chikungunya infection was detected although reported in neighboring Cambodia.A differential efficiency of serological dengue detection was observed.Efficiency was 29%upon admission and 53%after seven days on the same patients.30 patients out of 131(23%) were negative with both DENV and CHIKV.Conclusions:Dengue is at risk of being underestimated and chikungunya is not systematically detected.Changes in detection and surveillance procedures are therefore discussed to increase efficiency of dengue detection and continue the monitoring the emergence of CHIKV in Dong Thap province and in Vietnam.Pham Thi Kim Lien Laurence Briant Truong Ba Tang Bui Minh Trang Laurent Gavotte Emmanuel Comillot Vu Trong Duoc Tran Nhu Duong Roger Frutos Phan Thi Nga 2016Asian Pacific Journal of Tropical Medicine2016,9,1:0
12AB048.Pre-saccadic attentional facilitation is influenced by irrelevant post-saccadic changes显示文摘Background:Many studies have shown that attention is shifted toward the goal of the upcoming saccade.It has been suggested that the purpose of this attentional shift is to aid in trans-saccadic integration by acting as a‘pointer’(Cavanagh,Hunt,Afraz&Rolfs,2010)for remembering,processing and updating objects across saccadic eye movements(Rolfs,Jonikaitis,Deubel&Cavanagh,2011).We tested this hypothesis that pre-saccadic attentional facilitation acts as a pointer for trans-saccadic integration by investigating how irrelevant post-saccadic changes influenced pre-saccadic attentional discrimination.On one hand,if pre-saccadic attentional facilitation is an independent process involved only in enhancing peripheral information before the saccade,then manipulating visual information(absence or shift)after the saccade should have no influence on discrimination.On the other hand,if pre-saccadic attentional facilitation is involved in trans-saccadic integration,changes in visual information should influence discrimination of the pre-saccadic information.Methods:We tested different conditions involving different post-saccadic changes.In the baseline condition,participants made a saccade at the appearance of an arrow and discriminated a symbol(DS)that was presented briefly before the saccade at one of six peripheral locations.The symbol was masked thereafter with a figure 8,which remained till the end of the trial.Importantly,the DS was always presented while participants were fixating at center,and only the figure 8 was present at the end of the saccade.Participants were instructed to make the saccade then report the identity of the DS(4AFC).We then tested how blanking post-saccadic information[blanking of the saccade goal(SG)location,DSOff condition;of the entire visual scene including or excluding the SG location,AllOff and DSOnly conditions]and how displacement of the figure 8s after the saccade would affect performance.Results:We observed that discrimination performance was significantly lower when the SG location disappeared during the saccade and was no longer present when the saccade was completed(DSOff,-6.9%).This decrease in performance cannot be attributed to changes in the visual scene that may have drawn attention,as this was the case for all conditions;performance was not different when the entire visual scene was blanked(AllOff,-0.0%)or when only the DS remained(DSOnly,-1.6%).We also found that the performance decreased as a function of the displacement of the figure 8 from the SG location,particularly if it was displaced outside of the saccade landing zone.Conclusions:Based on these pattern of results,we suggest that pre-saccadic attentional facilitation is indeed involved in trans-saccadic integration by acting as a location marker or pointer.The lack of a visual target at the saccade goal,even if it is irrelevant to the pre-saccadic discrimination task,disrupted performance.Maxime Bleau Anne-Sophie Laurin Anton Malienko Trang Tran Laure Pisella Aarlenne Z.Khan 2018Annals of Eye Science2018,,1:0
13AB060.Peripheral attentional allocation during visual search in the presence of an artificial scotoma in younger and older adults显示文摘Background:Age related macular degeneration(AMD)is one of the main causes of vision loss in older adults,generating,in most cases,a central scotoma that reduces central visual acuity(Noble&Chaudhary,2010).People affected by AMD have to rely on peripheral visual information and would highly benefit from efficiently allocating their attention to the periphery.Indeed,attention can improve peripheral spatial resolution(Carrasco,Ling&Read,2004)and can be allocated to a certain expanse of space outside of the central visual span,known as the attentional span.Attentional span has been shown to be decreased in people with AMD with less attention allocated to the periphery and more to the central visual field(Cheong et al.,2008),however it remains unknown whether aging is also a contributing factor.Methods:Fourteen healthy younger(mean age=21.8 years,SD=1.5)and 8 older adults(mean age=69.6 years,SD=7.3)performed a pop-out and a serial version of a visual search task,in the presence of different sized gaze-contingent invisible and visible artificial central scotomata(no scotoma,3°diameter,5°and 7°).Participants were asked to indicate as quickly as possible whether a target was present or not among distractors whose number varied(16,32 or 64 objects).We wished to determine whether the size of the scotoma,occluding different degrees of central vision,affected visual search differently for younger vs.older participants.Results:Both the younger and older participants showed higher reaction times(RTs)to find the target for the serial version(M=2,074 ms for younger adults,M=3,853 ms for older adults)compared to the pop-out version(M=866 ms,M=1,475 ms,P<0.001)and for more distractors(32 distractors compared to 16,and 64 compared to 32,P<0.01).Older adults showed longer RTs than younger adults for both versions of the task(P<0.01).We found a significant effect of scotoma size on older adults(3°scotoma M=3,276 ms;7°scotoma M=3,877 ms,P<0.05),however,accurate performance was higher with no scotoma(96%vs.92%,P<0.05)in the pop-out search task.This suggests that older participants privileged a fast decision at the expense of performance in those cases.For the younger adults,RTs were higher in the serial search task in the presence of a scotoma(M=2,074 ms)compared to the control condition(M=1,665 ms,P>0.05).Conclusions:These results suggest that older adults take longer to perform visual search compared to younger adults and tend to use peripheral visual less than younger adults;larger central scotomas disrupted their performance but not that of younger participants,who performed equally well with different central scotoma sizes.These findings suggest that aging is a contributing factor in the decrease of the peripheral attentional span.Anne-Sophie Laurin Trang Tran Gunnar Blohm Laure Pisella Aarlenne Z.Khan 2018Annals of Eye Science2018,,1:0
14AB061. Changes in eye movement strategies during a discrimination task in the presence of artificial central scotomas显示文摘Background:The goal of the present research was to study whether the presence of an artificial central scotoma resulted in changes in eye movement strategies over the course of multiple days of training.We wished to determine how central vision loss,similar to age macular degeneration(AMD),affects eye movements,specifically the foveal-target alignment.We also wished to determine if an invisible compared to a visible scotoma led to delayed or different strategies,given that AMD patients are mostly unaware of their condition as they are unconscious of the presence of their central scotoma.Methods:Eleven healthy participants(6 females,M=22.18,SD=1.94)were asked to perform a discrimination task,where they responded whether the orientation of an eccentric target(Gabor,10 deg to the left of fixation)was clockwise or counter-clockwise.The target was surrounded by four distractor Gabors,thus making discrimination more difficult using peripheral vision.The target’s orientation varied 10°clockwise to 10°counter-clockwise in 1°intervals.Each participant performed four blocks of 75 trials each per day over 10 days,the first day being a baseline as the participant were tested without any scotoma.We measured discrimination performance and precision(position of the eye in X and Y).Results:Results showed similar patterns of discrimination reaction time and accuracy as well as changes to eye position for both the visible and the invisible scotoma conditions.Discrimination time significantly decreased on the last day of training compared to the first(first day M=2,965 ms,last day M=1,567 ms,P<0.05),while accuracy increased though not significantly so(first day=87.4%,last day=93.15%).There was no change in the final horizontal(X)position of first saccade relative to the target(first=−0.4°,last=−0.13°)but there was a significant upward shift(first=0.08°vs.last=0.58°,P<0.05);participants shifted their eye position on the Y axis so that they were looking at a point slightly above the target.Conclusions:These findings suggest that the presence of an artificial central scotoma induces both changes in saccade planning mechanisms as well as changes in peripheral visual function,possibly attentional,resulting in improved discrimination performance.This study allows a better comprehension of eye movement and attentional strategies during central visual loss and provides insight into possible rehabilitation strategies.Paul Lene Trang Tran Anne-Sophie Laurin Romain Fournet Frédéric Gosselin Aarlenne Z.Khan 2018Annals of Eye Science2018,,1:0
15Agrobacterium-Mediated Transformation of Cry8db Gene in Vietnam Sweet Potato Cultivar显示文摘Pham Bich Ngoc Vu Thi Lan Tran Thu Trang Nguyen Hoai Thuong Le Thu Ngoc Chu Hoang Ha Le Tran Binh 2015Journal of Life Sciences2015,9,6:0
16Properties of poly(1-naphthylamine)/Fe3O4 composites and arsenic adsorption capacity in wastewater显示文摘Minh Thi TRAN Thi Huyen Trang NGUYEN Quoc Trung VU Minh Vuong NGUYEN 2016Frontiers of Materials Science2016,10,1:0
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