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| 1 | 大豆提取物抗戊四唑所致卵巢切除大鼠痉挛的作用(英文)显示文摘目的:研究大豆提取物抗戊四唑所致卵巢切除大鼠痉挛的作用。方法:雌性Wistar大鼠随机分为4组(n=15),分别为假手术组、卵巢切除组、低剂量大豆提取物组和高剂量大豆提取物组。假手术组大鼠行假手术,其余3组大鼠行卵巢切除术。每组大鼠再随机分为2个亚组,其中一个亚组(n=7)每日予低剂量戊四唑(40mg/kg)腹腔内注射,连续14d;另一亚组(n=8)予一次高剂量戊四唑(90mg/kg)腹腔内注射。在戊四唑注射前30min,低剂量大豆提取物(20mg/kg)及高剂量大豆提取物(60mg/kg)组分别腹腔内注射大豆提取物,假手术组及卵巢切除组注射生理盐水。上述步骤完成后,将大鼠置于树脂玻璃箱中观察60min。结果:重复低剂量注射戊四唑14d,卵巢切除组大鼠的痉挛评分在第3、5、8、10、11、12及13天低于假手术组(P<0.05或P<0.01),而低剂量大豆提取物组和高剂量大豆提取物组大鼠的痉挛评分高于卵巢切除组(P<0.05或P<0.01)。一次性高剂量注射戊四唑后,与假手术组相比,卵巢切除组大鼠阵发性强直性抽搐潜伏期延长,而最小阵发性痉挛潜伏期无明显变化;与卵巢切除组相比,低剂量及高剂量的大豆提取物显著缩短了大鼠阵发性强直性抽搐及最小阵发性痉挛的潜伏期(P<0.01)。结论:雌激素能够影响戊四唑所致大鼠痉挛的严重程度,而大豆中所含的植物雌激素也具有类似作用,这种作用还有待更多的研究予以证实。 | Ali Reza Ebrahimzadeh Bideskan Mahmoud Hosseini Toktam Mohammadpour Reza Karami Mehdi Khodamoradi Habibollah Nemati Karimooy Hassan Alavi | 2011 | 中西医结合学报2011，9，6： | 4 |
| 2 | Accuracy of chest radiography versus chest computed tomography in hemodynamically stable patients with blunt chest trauma显示文摘ObjectiveThoracic 损害为钝损伤的 25% 死亡负责。胸 X 光检查(CXR ) 是在有钝损伤的病人的第一个诊断方法。学习是检测 CXR 对胸的精确性的这的目的与钝胸 trauma.MethodsStudy 在血液动力学地稳定的病人计算了 tomograpgy (CT ) 从 2011 年 3 月在 Sina 医院的紧急情况部门被进行到 2012 年 3 月。有钝胸损伤的有至少 16 岁的血液动力学地稳定的病人被包括。所有病人经历了由物理检查组成了的一样的诊断协议, CXR 和 CT 扫描 respectively.ResultsTwo 百病人(84%男性和16%女性)与吝啬的年龄被包括( 37.9 ±13.7 ) years.Rib 骨折是 CXR (12.5%)和 CT 扫描(25.5%)的最普通的发现。为 hemothorax, thoracolumbar 椎骨破裂和肋骨破裂的 CXR 的敏感分别地是 20% , 49% 和 49% 。当在有钝胸损伤的血液动力学地稳定的病人的首要的诊断形式能检测可以改变管理和结果的病理,气胸,外国身体,肺气肿,肺的殴打,肝 hematoma 和胸骨骨折没与 CXR alone.ConclusionApplying CT 扫描被诊断。 | Mojtaba Chardoli Toktam Hasan-Ghafiaee, Hesam Akbari Vafa Rahimi-Movaghat | 2013 | Chinese Journal of Traumatology2013，16，6： | 2 |
| 3 | Impact of the Basil and Balangu gums on physicochemical properties of part baked frozen Barbari bread显示文摘Part baking of bread and frozen storage as the new methods have attracted a lot of attention due to an increase in shelf life and the availability of fresh bread at any time.Replacing traditional additives with natural gums such as plant gum for producing bread with long shelf life is considered as a major technological challenge in bakery industry.The present study aimed to evaluate the effects of 0,0.3%,and 0.5%concentrations of plant gums including Basil and Balangu,compared to guar gum at 0.4%on the physicochemical properties such as specific volume,extensibility,hardness,and color parameter,as well as sensory properties of part baked frozen bread.The results indicated adding gums to bread decreased in hardness and increased in specific volume,extensibility,color parameter and sensory properties.Based on the comparison between plant gums and guar,Basil and Balangu could improve volume,porosity,and sensory score more than guar against the guar which was more effective on moisture content and firmness of Barbari bread.The best results were obtained in the interaction between Basil and Balangu gums on 0.5%concentration. | Toktam Hejrani Zahra Sheikholeslami SAli Mortazavi Mahdi Karimi Amir Hosesein Elhamirad | 2019 | Information Processing in Agriculture2019，6，3： | 1 |
| 4 | SDN-Based Data Offloading for 5G Mobile Networks显示文摘The rapid growth of 3G/4G enabled devices such as smartphones and tablets in large numbers has created increased demand formobile data services.Wi-Fi offloading helps satisfy the requirements of data-rich applications and terminals with improved multi-media.Wi-Fi is an essential approach to alleviating mobile data traffic load on a cellular network because it provides extra capaci-ty and improves overall performance.In this paper,we propose an integrated LTE/Wi-Fi architecture with software-defined net-working(SDN)abstraction in mobile backhaul and enhanced components that facilitate the move towards next-generation 5G mo-bile networks.Our proposed architecture enables programmable offloading policies that take into account real-time network condi-tions as well as the status of devices and applications.This mechanism improves overall network performance by deriving real-time policies and steering traffic between cellular and Wi-Fi networks more efficiently. | Mojdeh Amani Toktam Mahmoodi Mallikarjun Tatipamula Hamid Aghvami | 2014 | ZTE Communications2014，12，2： | 1 |
| 5 | Pre-operative evaluation of living kidney donors using computerized tomographic angiography (CTA) and conventional angiography: Comparison with intraoperative findings显示文摘 | Rahim Razavizadeh Kamyar Tabassi Toktam Rana | 2012 | Saudi Journal of Kidney Diseases and Transplantat2012，，3： | 1 |
| 6 | Voltammetric determination of norepinephrine in the presence of acetaminophen using a novel ionic liquid/multiwall carbon nanotubes paste electrode显示文摘 | Sadegh Salmanpour Toktam Tavana Ali Pahlavan Mohammad A. Khalilzadeh Ali A. Ensafi Hassan Karimi-Maleh Hadi Beitollahi Elaheh Kowsari Daryoush Zareyee | 2012 | Materials Science & Engineering C2012，，7： | 1 |
| 7 | Sensitive voltammetric determination of epinephrine in the presence of acetaminophen at a novel ionic liquid modified carbon nanotubes paste electrode显示文摘 | Toktam Tavana Mohammad A. Khalilzadeh Hassan Karimi-Maleh Ali A. Ensafi Hadi Beitollahi Daryoush Zareyee | 2012 | Journal of Molecular Liquids2012，，： | 1 |
| 8 | 溴化钾催化硫化物、硝酸铵和SiO_2-OSO_3H固体酸的氧化反应(英文)显示文摘A convenient and selective catalytic method for the sulfoxidation of aliphatic and aromatic sulfides by treatment of NH4NO3, silica sulfuric acid, wet SiO2 (50% w/w) and a catalytic amount of KBr in CH2Cl2 at room temperature was developed. Many sulfides can be selec-tively oxidized at room temperature in good to excellent yields. The reaction proceeds without over-oxidation to sulfones under mild conditions. | Arash GHORBANI-CHOGHAMARANI Mohammad Ali ZOLFIGOL Toktam RASTEGAR | 2009 | 催化学报2009，30，4： | 1 |
| 9 | Lavender and dodder combined herbal syrup versus citalopram in major depressive disorder with anxious distress: A double-blind randomized trial显示文摘Background: Major depressive disorder(MDD) accompanied by anxious distress is a chronic and disabling disorder. Its conventional drug therapies often have low patient compliance due to drug-related side effects. In Persian medicine, lavender-dodder syrup is one formula often recommended for such disorders.Objective: This study compares the effects of lavender-dodder syrup to the standard drug, citalopram, for treating MDD with anxious distress.Design, setting, participants and intervention: This six-week, double-blind, randomized, clinical trial was carried out in a psychiatric outpatient clinic. During the six-week intervention period, patients in citalopram group received citalopram tablets 20 mg/d plus 5 mL placebo syrup every 12 h;patients in group B received placebo tablets once daily plus 5 mL of lavender-dodder herbal syrup every 12 h.Main outcome measures: Primary outcome measures, depression and anxiety, were evaluated using the Hamilton Depression/Anxiety Rating Scales, and were scored at the beginning of the study and at weeks three and six. Secondary outcome measures including response to treatment and remission rates were also compared between the two groups.Results: Fifty-six participants with MDD and anxious distress were randomly assigned to two groups.Mean depression scores significantly decreased in citalopram and herbal groups at weeks three and six(time effect: P < 0.001), although the observed changes were not significantly different between the groups(intervention effect: P = 0.61). Mean anxiety scores were not significantly different between the two groups at week three(P = 0.75). However, at the end of week six, the observed decrease was significantly higher in the herbal syrup group than the citalopram group(intervention effect: P = 0.007).Conclusion: The herbal syrup is an effective and tolerable supplement for treating MDD with anxious distress.Trial registration number: IRCT2016102430459 N1 on Iranian Registry of Clinical Trials. | Toktam Sadat Firoozeei Majid Barekatain Mehrdad Karimi Arman Zargaran Shahin Akhondzadeh Hossein Rezaeizadeh | 2020 | Journal of Integrative Medicine2020，18，5： | 1 |
| 10 | Aurally aided visual search in the central visual field: effects of visual load and visual enhancement of the target显示文摘 | David R Toktam S Kourosh S | 1991 | Human Factors1991，33，4： | 1 |
| 11 | Effects of the Hydro-Alcoholic Extract of Nigella Sativa on Scopolamine-Induced Spatial Memory Impairment in Rats and Its Possible Mechanism显示文摘Objective:To evaluate the effect of Nigella sativa(NS) extract on memory performance and its possible mechanisms in scopolamine(Sco)-induced spatial memory impairment model using Morris water maze test.Methods:Thirty-two male Wistar rats were randomly divided into four groups.The control group received saline instead of both NS extract and Sco.The Sco group was treated by saline for two weeks,and was injected by Sco(2 mg/kg,intraperitoneally) 30 min before each trail in Morris water maze test.Sco+NS 200 and Sco+NS 400 groups were daily treated by 200 or 400 mg/kg of NS(intraperitoneally) for two weeks,respectively,and were finally injected by Sco30 min before Morris water maze test.The brains of animals were removed to determine the acetylcholinesterase(AChE) activity and oxidative stress criteria in cortical tissues.Results:Time latency and path length in the Sco group were significantly higher than in the control group(P<0.01),while the Sco+NS 400 group showed a significantly shorter traveled path length and time latency compared with the Sco group(P<0.01).AChE activity in the cortical tissues of the Sco group was significantly higher than the control group(P<0.01),while AChE activity in the Sco+NS200 and Sco+NS 400 groups was lower than the Sco group(P<0.01).Following Sco administration,malondialdehyde(MDA) concentrations were increased(P<0.01) in comparison with the control group,while cortical total thiol content decreased(P<0.01).Pretreatment with extracts caused a significant elevation in cortical total thiol content(P<0.01)and reduction in cortical MDA concentration(P<0.01) compared with the Sco group.Conclusions:Hydro-alcoholic extract of NS prevents Sco-induced spatial memory deficits and decreases the AChE activity as well as oxidative stress of brain tissues in rats.Our results support the traditional belief about the beneficial effects of NS in nervous system.Moreover,further investigations are needed for better understanding of this protective effect. | Mahmoud Hosseini Toktam Mohammadpour Reza Karami Ziba Rajaei Hamid Reza Sadeghnia Mohammad Soukhtanloo | 2015 | Chinese Journal of Integrative Medicine2015，21，6： | 0 |
| 12 | 黄豆提取物的雌激素依赖作用对戊四唑诱发的大鼠癫癎的影响(英文)显示文摘目的:研究黄豆提取物对经戊四唑(pentylenetrazole,PTZ)诱发癫发作的女性荷尔蒙缺失雌性大鼠与正常雌性大鼠的不同作用,以及因性别差异引起的植物雌性激素对行为的影响。方法:雄性Wistar大鼠被随机分为雄性生理盐水组,雄性低、中、高剂量黄豆提取物治疗组,每组8只;雌性Wistar大鼠随机分为假手术生理盐水组,假手术低、中、高剂量黄豆提取物治疗组,去卵巢生理盐水组,去卵巢低、中、高剂量黄豆提取物治疗组,每组8只。去卵巢大鼠在氯胺酮麻醉下行卵巢切除术。分别给予各组大鼠生理盐水及不同剂量黄豆提取物治疗2周后腹腔内注射戊四唑。将大鼠放置在树脂玻璃笼内,记录最小阵挛性癫发作(minial clonic seizure,MCS)潜伏期和强直性阵挛性癫发作(generalized tonic-clonic seizure,GTCS)潜伏期。结果:与雄性生理盐水组大鼠比较,雄性低、中剂量黄豆提取物治疗组的MSC和GTCS潜伏期显著缩短(P<0.05或P<0.01)。雌性假手术大鼠在给予黄豆提取物治疗后,其MSC和GTCS潜伏期没有显著改变。与去卵巢生理盐水组比较,去卵巢低、高剂量黄豆提取物治疗组的MSC和GTCS潜伏期明显缩短(P<0.05或P<0.01)。结论:黄豆的植物雌激素能影响由PTZ诱发的癫发作的轻重程度,但其影响程度与卵巢激素水平有关。机制还有待进一步研究。 | Toktam Mohammadpour Mahmoud Hosseini Reza Karami Hamid Reza Sadeghnia Ali Reza Ebrahimzadeh Bideskan Lili Enayatfard | 2012 | 中西医结合学报2012，10，12： | 0 |
| 13 | Solar-Assisted Space Heating and Small Pond-Assisted Space Cooling of a Highly Insulated Energy Efficient House显示文摘 | Toktam Saeid Hessam Taherian Alan S. Fung Humphrey Tse | 2012 | Journal of Civil Engineering and Architecture2012，6，8： | 0 |
| 14 | Novel treatments and genetics of age-related macular degeneration-a narrative review显示文摘Age-related macular degeneration(AMD)remains a leading cause of severe visual impairment in developing countries.Although dry-type AMD and geographic atrophy(GA)are progressive conditions with the associated decrease of visual functions,no well-established treatment regimen was proposed for the disease.Wet-type AMD is effectively treated with intravitreal anti-angiogenic agents,but frequent injections are a major issue for the affected patients.Recent advances in AMD genetics have provided new insights into the pathogenesis and novel therapeutic targets of AMD,but the benefits of using genetic testing and genotype-based risk models for AMD development and progression still lacks evidence.Novel AMD treatments aim to increase the interval among intravitreal injections through new therapeutic agents and modern delivery devices.Simultaneously,gene therapy for dry and wet AMD is widely studied.Although gene therapy possesses a major superiority over other novel treatments regarding a persistent cure of disease,many challenges exist in the way of its broad impact on the ocular health of AMD patients. | Amir Arabi Toktam Shahraki | 2021 | Annals of Eye Science2021，，4： | 0 |
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