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| 1 | Lack of CD44 variant 6 expression in rectal cancer invasive front associates with early recurrence显示文摘AIM: To investigate the prognostic value of CD44 variant 6 (CD44v6), a membranous adhesion molecule, in rectal cancer. METHODS: Altogether, 210 rectal cancer samples from 214 patients treated with short-course radiotherapy (RT, n = 90), long-course (chemo) RT (n = 53) or surgery alone (n = 71) were studied with immunohistochemistry for CD44v6. The extent and intensity of membranous and cytoplasmic CD44v6 staining, and the intratumoral membranous staining pattern, were analyzed.RESULTS: Membranous CD44v6 expression was seen in 84% and cytoplasmic expression in 81% of the cases. In 59% of the tumors with membranous CD44v6 expression, the staining pattern in the invasive front was determined as 'front-positive' and in 41% as 'front-negative'. The latter pattern was associated with narrower circumferential margin (P = 0.01), infiltrative growth pattern (P < 0.001), and shorter disease-free survival in univariate survival analysis (P = 0.022) when compared to the 'front-positive' tumors. CONCLUSION: The lack of membranous CD44v6 in the rectal cancer invasive front could be used as a method to identify patients at increased risk for recurrent disease. | Suvi Tuulia Avoranta Eija Annika Korkeila Kari Juhani Syrjnen Seppo Olavi Pyrhnen Jari Toivo Tapio Sundstrm | 2012 | World Journal of Gastroenterology2012，18，33： | 9 |
| 2 | Plant sterols in vegetables,fruits and berries显示文摘 | Vieno Piironen Jari Toivo | 2003 | Journal of the Science of Food and Agriculture2003，83，： | 1 |
| 3 | Factors affecting sample preparation in the gas chromatographic determination of plant sterols in whole wheat flour显示文摘 | Toivo J Lampi A M Aalto S | 2000 | Food Chemistry2000，68，2： | 1 |
| 4 | Determination of sterols in foods: Recovery of free, esterified, and glyco- sidic sterols 显示文摘 | Toivo J Phillips K Lampi A M | 2001 | Journal of Food Composition and Analy- sis2001，14，6： | 1 |
| 5 | The activity of Pt/A1203 diesel oxidation catalyst after sulphur and calcium treatments显示文摘 | TANJA K TOMI K MIKA H MINNAMARI V KAUKO K TONI K TOIVO L JOUKO L RIITFA K | 2010 | Catal Today2010，154，34： | 1 |
| 6 | Free and EsterifiedSterol Composition of Edible Oils and Fats 显示文摘 | Phillips K M Ruggio D M Toivo J I | 2002 | Journal of FoodComposition and Analysis2002，15，2： | 1 |
| 7 | New Generation Network Architecture and Software Design显示文摘 | Kristian Toivo | 2000 | IEEE Communications2000，38，2： | 1 |
| 8 | The theoretical and philosophical underpinnings of relationship marketing:Environmental factors behind the changing marketing paradigm显示文摘 | TOIVO S A | 1996 | Furopean Journal of Marketing1996，30，2： | 1 |
| 9 | Free and Esterified Sterol Composition of Edible Oils and Fats显示文摘 | Katherine M. Phillips David M. Ruggio Jari I. Toivo Molly A. Swank Amy H. Simpkins | 2002 | Journal of Food Composition and Analysis2002，，2： | 1 |
| 10 | Natural source of dietary plant sterols显示文摘 | Piironen V Toivo J Lampi A M | 2000 | Journal of Food Composition and Analysis2000，13，： | 1 |
| 11 | Determination of thermo-oxidation products of plant sterols显示文摘 | LAMPI A M JUNTUNEN L TOIVO J | 2002 | Journal of Chromatography B2002，777，： | 1 |
| 12 | Plant sterols in vegetables,fruits and berries显示文摘 | Vieno Piironen Jari Toivo Riitta Puupponen-Pimia | 2003 | Journal of the Science of Food and Agriculture2003，83，： | 1 |
| 13 | Determination of steruls in foods: recovery of free, esterifiedand glycosidic sterols显示文摘 | Jari Toivo Katherine Phillips Anna -Maija Lampi | 2001 | Journal of Food Composition and Analysis2001，14，： | 1 |
| 14 | Sterol and vitamin D 2 contents in some wild and cultivated mushrooms显示文摘 | Pirjo Mattila Anna-Maija Lampi Riitta Ronkainen Jari Toivo Vieno Piironen | 2002 | Food Chemistry2002，，3： | 1 |
| 15 | Study of immersion silver and tin printed-circuit-board surface finishes in leadfree solder applications显示文摘 | Arra Minna Shangguan Dongkai Xie Dongji Sundelin Janne Lepisto Toivo Ristolainen Eero | 2004 | Journal of Electronic Materials2004，33，9： | 1 |
| 16 | 显示文摘 | PIIRONEN V TOIVO J LAMPI A M | 2002 | Journal of Food Composition and Analysis2002，15，： | 1 |
| 17 | Changes in body fluids during endurance rowing training显示文摘 | JAAK JURIMAE TOIVO JURIMAE EVE PIHL | 2000 | Annals New York Academy Sci2000，904，： | 1 |
| 18 | Factors affecting sample preparation in the gas chromatographic determination of plant sterols in whole wheat flour 显示文摘 | Toivo J Lampi A M Aaho S | 2000 | Food Chemistry2000，68，2： | 1 |
| 19 | Natural source of dieta- ry plant sterols 显示文摘 | Piironen V Toivo J Lampi A M | 2000 | Journal of Food Composition and A- nalysis2000，13，4： | 1 |
| 20 | Factors affecting sample preparation in the gas chromatographic determination of plant sterols in whole wheat flour显示文摘 | J Toivo A-M Lampi S Aalto | | 0，，： | 1 |
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