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| 1 | Non-small-bowel lesions encountered during double-balloon enteroscopy performed for obscure gastrointestinal bleeding显示文摘AIM:To report the incidence of non-small-bowel bleeding pathologies encountered during double-balloon enteroscopy (DBE) procedures and to analyse their significance.METHODS: A retrospective study of a prospective DBE database conducted in a tertiary-referral center was conducted. A total of 179 patients with obscure gastrointestinal bleeding (OGIB) referred for DBE from June 2004 to November 2008 were analysed looking for the incidence of non-small-bowel lesions (NSBLs; all and newly diagnosed) encountered during DBE.RESULTS: There were 228 (150 antegrade and 78 retrograde) DBE procedures performed in 179 patients. The mean number of DBE procedures was 1.27 per patient. The mean age (SD) of the patients was 62 ± 16 years old. There were 94 females (52.5%). The positive yield for a bleeding lesion was 65.9%. Of the 179 patients, 44 (24.6%) had NSBLs (19 of them had dual pathology with small-bowel lesions and NSBLs); 27 (15.1%) had lesions not detected by previous endoscopies. The most common type of missed lesions were vascular lesions.CONCLUSION: A significant proportion of patients (24.6%) had lesions within reach of conventional endoscopy. Careful repeat examination with gastroscopy and colonoscopy might be required. | Hoi-Poh Tee Arthur J Kaffes | 2010 | World Journal of Gastroenterology2010，16，15： | 21 |
| 2 | Nitric oxide synthase and heme oxygenase expressions in human liver cirrhosis显示文摘瞄准:门静脉高血压是肝肝硬化的普通复杂并发症。肝内压力能以几个方法被提高。从内脏的内脏影响脉管系统, vasoconstrictors 的增加和增加的循环进门静脉系统的反常建筑学都可以作出贡献。因而内长的血管扩张药也许能减轻高血压。我们因此试图调查内长的血管扩张药的层次,氮的氧化物(没有) 并且通过氮的氧化物 synthase (NOS ) 的表示的一氧化碳(公司) 并且他我氧合酶(惊讶) 。方法:肝脏硬化症(n=20 ) 并且非肝脏硬化症(n=20 ) 肝从经历了外科的病人被获得。NOS 的各种各样的 isoforms 的 mRNA 和蛋白质表情并且惊讶用竞争 PCR,西方的污点和免疫组织化学被检验。结果:当内皮 NOS (eNOS ) 在硬变肝是起来调整的时,在可诱导的 NOS (i NOS ) 或神经元 NOS (nNOS ) 表情没有重要变化。附随地, caveolin-1, eNOS 的一个确定的下面管理者,是起来调整的。可诱导的 HO-1 和组成的 HO-2 被发现在不同本地化在硬变肝虽然显示出增加的表示。结论:NOS 表示力量的差别由于他们在在肝硬化的病理维持肝动态平衡或参与的不同角色。在高血压的肝以内的纯粹的应力可以导致 eNOS 的增加的表示。接着, caveolin-1 也被增加。这是否对进一步的肝硬化用作一个防御机理或是肝硬化的后果,是还未知的。HO-1 和 HO-2 的提高的表示建议公司可以微弱地作为血管扩张药虽然在它的角色补偿。它是可能的那个公司并且不在肝以内有平行或协调的功能并且可以在门静脉高血压的病理生理学反对地工作。 | Beatrice J Goh Bee Tee Tan Wei Min Hon Kang Hoe Lee Hoon Eng Khoo | 2006 | World Journal of Gastroenterology2006，12，4： | 19 |
| 3 | Prospective randomized controlled trial evaluating cap-assisted colonoscopy vs standard colonoscopy显示文摘AIM: To study the significance of cap-fitted colonoscopy in improving cecal intubation time and polyp detection rate. METHODS: This study was a prospective randomized controlled trial conducted from March 2008 to February 2009 in a tertiary referral hospital at Sydney. The primary end point was cecal intubation time and the secondary endpoint was polyp detection rate. Consecutive cases of total colonoscopy over a 1-year period were recruited. Randomization into either standard colonoscopy (SC) or cap-assisted colonoscopy (CAC) was performed after consent was obtained. For cases randomized to CAC, one of the three sizes of cap was used: D-201-15004 (with a diameter of 15.3 mm), D-201-14304 (14.6 mm) and D-201-12704 (13.0 mm). All of these caps were produced by Olympus Medical Systems, Japan. Independent predictors for faster cecal time and better polyp detection rate were also determined from this study. RESULTS: There were 200 cases in each group. There was no signif icant difference in terms of demographic characteristics between the two groups. CAC, when compared to the SC group, had no signif icant difference in terms of cecal intubation rate (96.0% vs 97.0%, P = 0.40) and time (9.94 ± 7.05 min vs 10.34 ± 6.82 min, P = 0.21), or polyp detection rate (32.8% vs 31.3%, P = 0.75). On the subgroup analysis, there was no significant difference in terms of cecal intubation time by trainees (88.1% vs 84.8%, P = 0.40), ileal intubation rate (82.5% vs 79.0%, P = 0.38) or total colonoscopy time (23.24 ± 13.95 min vs 22.56 ± 9.94 min, P = 0.88). On multivariate analysis, the independent determinants of faster cecal time were consultant-performed procedures (P < 0.001), male patients (P < 0.001), non-usage of hyoscine (P < 0.001) and better bowel preparation (P = 0.01). The determinants of better polyp detection rate were older age (P < 0.001), no history of previous abdominal surgery (P = 0.04), patients not having esophagogastroduodenoscopy in the same setting (P = 0.003), trainee-performed procedures (P = 0.01), usage of hyoscine (P = 0.01) and procedures performed for polyp follow-up (P = 0.01). The limitations of the study were that it was a single-center experience, no blinding was possible, and there were a large number of endoscopists. CONCLUSION: CAC did not signif icantly different from SC in term of cecal intubation time and polyp detection rate. | Hoi-Poh Tee Crispin Corte Hamdan Al-Ghamdi Emilia Prakoso John Darke Raman Chettiar Wassim Rahman Scott Davison Sean P Griffin Warwick S Selby Arthur J Kaffes | 2010 | World Journal of Gastroenterology2010，16，31： | 10 |
| 4 | Placement of removable metal biliary stent in post-orthotopic liver transplantation anastomotic stricture显示文摘Postoperative biliary strictures are the most common cause of benign biliary stricture in Western countries, secondary to either operative injury or bile duct anastomotic stricture following orthotopic liver transplantation(OLT).Surgery or endoscopic interventions are the mainstay of treatment for benign biliary strictures.We aim to report the outcome of 2 patients with refractory anastomotic biliary stricture post-OLT,who had successful temporary placement of a prototype removable covered self-expandable metal stent(RCSEMS).These 2 patients(both men,aged 44 and 53 years)were given temporary placement of a prototype RCSEMS (8.5 Fr gauge delivery system,8 mm×40 mm stent dimensions)in the common bile duct across the biliary stricture.There was no morbidity associated with stent placement and removal in these 2 cases.Clinical parameters improved after the RCSEMS placement.Longterm biliary patency was achieved in both the patients. No further biliary intervention was required within 14 and 18 mo follow-up after stent removal. | Hoi-Poh Tee Martin W James Arthur J Kaffes | 2010 | World Journal of Gastroenterology2010，16，28： | 4 |
| 5 | 为双汽球 enteroscopy 的学习曲线: 从 282 过程的分析的调查结果显示文摘 AIM: To determine the learning curves for antegrade double-balloon enteroscopy (aDBE) and retrograde DBE (rDBE) by analyzing the technical success rates. METHODS: A retrospective analysis in a tertiary referral center. This study reviewed all cases from June 2006 to April 2011 with a target lesion in the small-bowel identified by either capsule endoscopy or computed tomography scan posted for DBE examinations. Main outcome measurements were: (1) Technical success of aDBE def ined by f inding or excluding a target lesion after achieving suff icient length of small bowel intubation; and (2) Technical success for rDBE was def ined by either f inding the target lesion or achieving stable overtube placement in the ileum. RESULTS: Two hundred and eighty two procedures fulf illed the inclusion criteria and were analyzed. These procedures were analyzed by blocks of 30 cases. Therewas no distinct learning curve for aDBE. Technical success rates for rDBE continued to rise over time, although on logistic regression analysis testing for trend, there was no signif icance (P = 0.09). The odds of success increased by a factor of 1.73 (95% CI: 0.93-3.22) for rDBE. For these data, it was estimated that at least 30-35 cases of rDBE under supervision were needed to achieve a good technical success of more than 75%. CONCLUSION: There was no learning curve for aDBE. Technical success continued to increase over time for rDBE, although a learning curve could not be proven statistically. Approximately 30-35 cases of rDBE will be required for stable overtube intubation in ileum. | Hoi-Poh Tee Soon-Hin How Arthur J Kaffes | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，8： | 4 |
| 6 | Formation of Colloidal CuO Nanocrystallites and Their Spherical Aggregation and Reductive Transformation to Hollow Cu20 Hollow Nanospheres显示文摘 | Chang Y Tee J Zeng H C | 2005 | Langrnuir2005，21，： | 1 |
| 7 | Chaotic Behavior in Erbium-doped Fiber Ring Lasers显示文摘 | Luo L G Tee T J Chu P L | 1998 | J Opt Soc Am B1998，15，3： | 1 |
| 8 | A microcantilever device to assess the effect of force on the lifetime of selectincarbohydrate bonds显示文摘 | Tees DF J Waugh RE Hammer DA | 2001 | Biophys J2001，80，： | 1 |
| 9 | International Measures of Schooling Years and Schooling Quality显示文摘 | Barro R J tee J W | 1996 | American Economic Review1996，86，2： | 1 |
| 10 | Skin-like pressure and strain sensors based on transparent e- lastic films of carbon nanotubes 显示文摘 | LIPOMI D J VOSGUERITCHIAN M TEE B C K | 2011 | Nature Nanotechnolo- gy2011，6，12： | 1 |
| 11 | Temporal and spatial dynamics of human immunodeficiency virus type 1 circulating recombinant forms 08_BC and 07BC in Asia 显示文摘 | Tee KK Pybus OG Li X J | 2008 | J Virol2008，82，18： | 1 |
| 12 | Stret- chable organic solar cells显示文摘 | Lipomi D J Tee B C K Vosgueritchian M | 2011 | Adv Mater2011，23，： | 1 |
| 13 | Anchoring skeletal muscledevelopment and disease:the role of ankyrin repeat domiancontaining proteins in muscle physiology显示文摘 | TEE J M PEPPELENBOSCH M P | 2010 | Critical Reviews inBiochemistry and Molecular Biology2010，45，4： | 1 |
| 14 | The influence of follower mood on leader mood and task performance: an affective, follower-centric perspective of leadership显示文摘 | Tee E Y J Ashkanasy N M Paulsen N | 2013 | The Leadership Quarterly2013，24，4： | 1 |
| 15 | Isolation of group 2 aerotolerant Campylobacter species from Thai children with diarrhea显示文摘 | TAYLOR D N KIEHLBAUCH J A TEE W | 1991 | J Infect Dis1991，163，： | 1 |
| 16 | mTOR con- trois cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E 显示文摘 | Fingar D C Richardson C J Tee A R | 2004 | Mol Cell Biol2004，24，1： | 1 |
| 17 | The impact of clinical protocols in the management of severe sepsis:a prospective cohort study显示文摘 | Phua J Ho BC Tee A | | 0，，04： | 1 |
| 18 | Antioxidant properties of severaltropical fruits : A comparative study显示文摘 | LIM Y Y LIM T T TEE J J | 2007 | Food Chemistry2007，103，3： | 1 |
| 19 | Glypican-3 modulates BMP-and FGF-mediated effects during renal branching morphogenesis 显示文摘 | Cano-Gauci J Tee J | 2001 | Dev Biol2001，231，： | 1 |
| 20 | Development of a rapid and automated TEM sample preparation method in semiconductor failure analysis and the study of the relevant TEM artifact显示文摘 | Tee S F Tay C L | 2001 | Microelectron J2001，32，3： | 1 |
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