|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Recommendations to quantify villous atrophy in video capsule endoscopy images of celiac disease patients显示文摘AIM To quantify the presence of villous atrophy in endoscopic images for improved automation.METHODS There are two main categories of quantitative descriptors helpful to detect villous atrophy:(1) Statistical and(2) Syntactic. Statistical descriptors measure the small intestinal substrate in endoscope-acquired images based on mathematical methods. Texture is the most commonly used statistical descriptor to quantify villous atrophy. Syntactic descriptors comprise a syntax, or set of rules, for analyzing and parsing the substrate into a set of objects with boundaries. The syntax is designed to identify and distinguish three-dimensional structures based on their shape.RESULTS The variance texture statistical descriptor is useful to describe the average variability in image gray level representing villous atrophy, but does not determine the range in variability and the spatial relationships between regions. Improved textural descriptors will incorporate these factors, so that areas with variability gradients and regions that are orientation dependent can be distinguished. The protrusion syntactic descriptor is useful to detect three-dimensional architectural components, but is limited to identifying objects of a certain shape. Improvement in this descriptor will require incorporating flexibility to the prototypical template, so that protrusions of any shape can be detected, measured, and distinguished.CONCLUSION Improved quantitative descriptors of villous atrophy are being developed, which will be useful in detecting subtle, varying patterns of villous atrophy in the small intestinal mucosa of suspected and known celiac disease patients. | Edward J Ciaccio Govind Bhagat Suzanne K Lewis Peter H Green | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，18： | 3 |
| 2 | Implementation of a polling protocol for predicting celiac disease in videocapsule analysis显示文摘AIM: To investigate the presence of small intestinal villous atrophy in celiac disease patients from quantitative analysis of videocapsule image sequences.METHODS: Nine celiac patient data with biopsy-proven villous atrophy and seven control patient data lacking villous atrophy were used for analysis. Celiacs had biopsy-proven disease with scores of Marsh Ⅱ-Ⅲ C except in the case of one hemophiliac patient. At four small intestinal levels (duodenal bulb, distal duodenum, jejunum, and ileum), video clips of length 200 frames (100 s) were analyzed. Twenty-four measurements were used for image characterization. These measurements were determined by quantitatively processing the videocapsule images via techniques for texture analysis, motility estimation, volumetric reconstruction using shape-from-shading principles, and image transformation. Each automated measurement method, or automaton, was polled as to whether or not villous atrophy was present in the small intestine, indicating celiac disease. Each automaton's vote was determined based upon an optimized parameter threshold level, with the threshold levels being determined from prior data. A prediction of villous atrophy was made if it received the majority of votes (≥ 13), while no prediction was made for tie votes (12-12). Thus each set of images was classified as being from either a celiac disease patient or from a control patient. RESULTS: Separated by intestinal level, the overall sensitivity of automata polling for predicting villous atrophy and hence celiac disease was 83.9%, while the specificity was 92.9%, and the overall accuracy of automata-based polling was 88.1%. The method of image transformation yielded the highest sensitivity at 93.8%, while the method of texture analysis using subbands had the highest specificity at 76.0%. Similar results of prediction were observed at all four small intestinal locations, but there were more tie votes at location 4 (ileum). Incorrect prediction which reduced sensitivity occurred for two celiac patients with Marsh type Ⅱ pattern, which is characterized by crypt hyperplasia, but normal villous architecture. Pooled from all levels, there was a mean of 14.31 ± 3.28 automaton votes for celiac vs 9.67 ± 3.31 automaton votes for control when celiac patient data was analyzed (P<0.001). Pooled from all levels, there was a mean of 9.71 ± 2.8128 automaton votes for celiac vs 14.32 ± 2.7931 automaton votes for control when control patient data was analyzed (P<0.001). CONCLUSION: Automata-based polling may be useful to indicate presence of mucosal atrophy, indicative of celiac disease, across the entire small bowel, though this must be confirmed in a larger patient set. Since the method is quantitative and automated, it can potentially eliminate observer bias and enable the detectionof subtle abnormality in patients lacking a clear diagnosis. Our paradigm was found to be more efficacious at proximal small intestinal locations, which may suggest a greater presence and severity of villous atrophy at proximal as compared with distal locations. | Edward J Ciaccio Christina A Tennyson Govind Bhagat Suzanne K Lewis Peter H Green | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，7： | 3 |
| 3 | Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial显示文摘 | Surya SAY Biere Mark I van Berge Henegouwen Kirsten W Maas Luigi Bonavina Camiel Rosman Josep Roig Garcia Suzanne S Gisbertz Jean HG Klinkenbijl Markus W Hollmann Elly SM de Lange H Jaap Bonjer Donald L van der Peet Miguel A Cuesta | 2012 | The Lancet . 2012 (9829)2012，，： | 3 |
| 4 | Celiac disease:Management of persistent symptoms in patients on a gluten-free diet显示文摘AIM:To investigate all patients referred to our center with non-responsive celiac disease (NRCD),to establish a cause for their continued symptoms.METHODS:We assessed all patients referred to our center with non-responsive celiac disease over an 18-mo period.These individuals were investigated to establish the eitiology of their continued symptoms.The patients were first seen in clinic where a thorough history and examination were performed with routine blood work including tissue transglutaminase antibody measurement.They were also referred to a specialist gastroenterology dietician to try to identift any lapses in the diet and sources of hidden gluten ingestion.A repeat small intestinal biopsy was also performed and compared to biopsies from the referring hospital where possible.Colonoscopy,lactulose hydrogen breath testing,pancreolauryl testing and computed tomography scan of the abdomen were undertaken if the symptoms persisted.Their clinical progress was followed over a minimum of 2 years.RESULTS:One hundred and twelve consecutive patients were referred with NRCD.Twelve were found not to have celiac disease (CD).Of the remaining 100 patients,45% were not adequately adhering to a strict gluten-free diet,with 24 (53%) found to be inadvertently ingesting gluten,and 21 (47%) admitting noncompliance.Microscopic colitis was diagnosed in 12% and small bowel bacterial overgrowth in 9%.Refractory CD was diagnosed in 9%.Three of these were diagnosed with intestinal lymphoma.After 2 years,78 patients remained well,eight had continuing symptoms,and four had died.CONCLUSION:In individuals with NRCD,a remediable cause can be found in 90%:with continued gluten ingestion as the leading cause.We propose an algorithm for investigation. | David H Dewar Suzanne C Donnelly Simon D McLaughlin Matthew W Johnson H Julia Ellis Paul J Ciclitira | 2012 | World Journal of Gastroenterology2012，18，12： | 2 |
| 5 | Grip Strength,Postural Control, and Functional Leg Power in a Representative Cohort of British Men and Women:Associtions With Physical Activity, Health Status, and Socioeconomic Conditions 显示文摘 | Diana K Bassey EJ Suzanne B Rebecca H | 2005 | The Journals of Gerontology: Series A : Biological sciences and medical sciences2005，60，2： | 1 |
| 6 | Global strategy for the di- agnosis, management, and prevention of chronic obstructive pulmonary disease GOLD executive summary显示文摘 | Klaus FR Suzanne H Antonio A | 2007 | Am J Re- spir Crit Care Med2007，176，4： | 1 |
| 7 | Course of platelet aetivationand platelet leukoeyte interaetionin ce-rebrovaseular isehemia显示文摘 | Patrik H Suzanne FM | 2006 | Stroke2006，37，9： | 1 |
| 8 | Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial显示文摘 | Surya SAY Biere Mark I van Berge Henegouwen Kirsten W Maas Luigi Bonavina Camiel Rosman Josep Roig Garcia Suzanne S Gisbertz Jean HG Klinkenbijl Markus W Hollmann Elly SM de Lange H Jaap Bonjer Donald L van der Peet Miguel A Cuesta | 2012 | The Lancet2012，，9829： | 1 |
| 9 | Grain size dependency in the occurrence of sand waves显示文摘 | Hennie Henri?t Veen Suzanne Jacqueline Marie Hélène Hulscher Michiel Adrianus Frederik Knaapen | 2006 | Ocean Dynamics (-)2006，，3： | 1 |
| 10 | Dimethylsulfoniopropi- onate cleavage by marine phytoplankton in response to mechani- cal,chemical or dark stress显示文摘 | Gordon V W Suzanne L S Jan L H | 2002 | Journal of Phycology2002，38，： | 1 |
| 11 | Incidence and importance of antibody responses to infliximab after maintenance or episodic treatment in Crohn’s disease显示文摘 | Stephen B Hanauer Carrie L Wagner Mohan Bala Lloyd Mayer Suzanne Travers Robert H Diamond Allan Olson Warren Bao Paul Rutgeerts | 2004 | Clinical Gastroenterology and Hepatology2004，，7： | 1 |
| 12 | Biovailability of isoflavones 显示文摘 | SUZANNE H | 2002 | J Chromatography B2002，777，： | 1 |
| 13 | Stress at college :Effects on health habits, health status and self- esteem显示文摘 | ]Suzanne S H Jennifer D Diane E S | 2000 | Journal of Social Psychiatry2000，43，： | 1 |
| 14 | Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary显示文摘 | Klaus F Suzanne H Antonio A | 2007 | Respir Crit Care Med2007，176，5： | 1 |
| 15 | The relationship between UK hospital nurse staffing and emotional exhaustion and job dissatisfaction 显示文摘 | Louisa S Jennifer H Suzanne H | 2005 | Journal of Nursing Management2005，，13： | 1 |
| 16 | Profiting from Intellectual Capital: Learning from Leading Companies 显示文摘 | HARRISON SUZANNE SULLIVAN H PATRICK Sr | 2000 | 1 (1): 33-462000，1，1： | 1 |
| 17 | Quadrivalent vaccine against human papillomavirus to prevent anogenital diseases显示文摘 | Suzanne M Garland M H Cosette M | 2007 | The New England Journal of Medicine2007，356，： | 1 |
| 18 | Effect of food processing on the stability of food allergens显示文摘 | Shridhar K Suzanne S Teuber K H | 2005 | Biotechnol Adv2005，23，： | 1 |
| 19 | Global strategy for the diagnosis,management,and prevention of chronic obstructive pulmonary disease GOLD executive summary显示文摘 | Klaus FR Suzanne H Antonio A | 2007 | Am J Respir Crit Care Med2007，176，4： | 1 |
| 20 | Comparing uncertain alternatives for a possible airport island location in the North Sea显示文摘 | Caroline S K Suzanne J M H H Teunis L | 2003 | Ocean & Coastal Management2003，46，1112： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员