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| 1 | Anti-inflammatory and Antimicrobial Effects of Anthocyanin Extracted from Black Soybean on Chronic Bacterial Prostatitis Rat Model显示文摘Objective: To investigated the anti-inflammatory and antimicrobial effects of anthocyanins extracted from black soybean on the chronic bacterial prostatitis(CBP) rat model.Methods: The SpragueDawley rats were divided into 4 groups,including control,ciprofloxacin,anthocyanins and anthocyanins with ciprofloxacin groups(n=8 in each group).Then,drip infusion of bacterial suspension(Escherichia coli Z17O_2:K_1:H^-) into Sprague-Dawley rats was conducted to induce CBP.In 4 weeks,results of prostate tissue,urine culture,and histological analysis on the prostate were analyzed for each group.Results: The use of ciprofloxacin,anthocyanins,and anthocyanins with ciprofloxacin showed statistically significant decreases in bacterial growth and improvements in the reduction of prostatic inflammation compared with the control group(P<0.05).The anthocyanins with ciprofloxacin group showed a statistically significant decrease in bacterial growth and improvement in prostatic inflammation compared with the ciprofloxacin group(P<0.05).Conclusions: These results suggest that anthocyanins may have anti-inflammatory and antimicrobial effects,as well as a synergistic effect with ciprofloxacin.Therefore,we suggest that the combination of anthocyanins and ciprofloxacin may be effective in treating CBP to obtain a higher rate of treatment success. | Byung Il Yoon Woong Jin Bae Yong Sun Choi Su Jin Kim U Syn Ha Sung-Hoo Hong Dong Wan Sohn Sae Woong Kim | 2018 | Chinese Journal of Integrative Medicine2018，24，8： | 11 |
| 2 | Rational use of mesenchymal stem cells in the treatment of autism spectrum disorders显示文摘Autism and autism spectrum disorders(ASD) refer to a range of conditions characterized by impaired social and communication skills and repetitive behaviors caused by different combinations of genetic and environmental influences. Although the pathophysiology underlying ASD is still unclear, recent evidence suggests that immune dysregulation and neuroinflammation play a role in the etiology of ASD. In particular, there is direct evidence supporting a role for maternal immune activation during prenatal life in neurodevelopmental conditions. Currently, the available options of behavioral therapies and pharmacological and supportive nutritional treatments in ASD are only symptomatic. Given the disturbing rise in the incidence of ASD, and the fact that there is no effective pharmacological therapy for ASD, there is an urgent need for new therapeutic options. Mesenchymal stem cells(MSCs) possess immunomodulatory properties that make them relevant to several diseases associated with inflammation and tissue damage. The paracrine regenerative mechanisms of MSCs are also suggested to be therapeutically beneficial for ASD.Thus the underlying pathology in ASD, including immune system dysregulation and inflammation, represent potential targets for MSC therapy. This review willfocus on immune dysfunction in the pathogenesis of ASD and will further discuss the therapeutic potential for MSCs in mediating ASD-related immunological disorders. | Qiang Liu Mo-Xian Chen Lin Sun Chloe U Wallis Jian-Song Zhou Li-Juan Ao Qi Li Pak C Sham | 2019 | World Journal of Stem Cells2019，11，2： | 5 |
| 3 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 4 | Pampas grass-inspired FeOOH nanobelts as high performance anodes for sodium ion batteries显示文摘High-performance materials are the key to developing new alternative energy-storage systems[1-4].Sodium ion batteries(SIBs)are regarded as the promising large-scale electric energy storage owing to the high abundance and low cost of sodium resources[1,5-9].However,the sluggish kinetics of Na^(+)caused by the large-sized Na^(+)(1.02A)result in the lower energy density and unsatisfactory electrochemical properties[10-14]. | Lianyi Shao Shige Wang Fangdan W u Xiaoyan Shi Zhipeng Sun Yuxin Tang | 2021 | Journal of Energy Chemistry2021，30，3： | 2 |
| 5 | CLINICAL AND GENETIC ANALYSIS OF THREE FAMILIES WITH FAMILIAR AMYLOID POLYNEUROPATHY显示文摘Objective To study the clinical and genetic features of familiar amyloid polyneuropathy (FAP). Methods Three families of suspected FAP in China mainland and Macao were investigated on aspects of clinical manifestations, histological features, and gene analysis. Results All the 3 families had the clinical features of sensory and motor polyneuropathies, and notable vegetative nerve involvements. Affected cases of one family had ultrasound proved cardiomyopathy. Histological studies showed amyloid deposition in all the biopsy tissues of the affected cases of the 3 families, and anti-transthyretin antisera staining was positive in 3 cases of one family. Gene analysis confirmed that mutation types were amyloidogenic transthyretin (ATTR) Val30Met, Phe33Val, and Gly67Glu in the 3 families respectively. The ATTR Gly67Glu family had a shorter survival time due to the heart involvement compared with the other 2 families. Conclusion FAP is an autosomal dominant inherited disease, with its clinical manifestations related to the type of genetic mutation. | Yan-feng Li Hou Ng Iok Sun U Waii Leong | 2008 | Chinese Medical Sciences Journal2008，23，4： | 2 |
| 6 | Fast text searching allowing errors显示文摘 | Sun W Manber U | 1992 | Com- munications of the ACM1992，35，10： | 1 |
| 7 | Investigating protein structure change in the zona pellucida with a micmrobotic system 显示文摘 | SUN Y U BRADLEY J NELSON | 2005 | The International Journal of Robotics Research2005，，24： | 1 |
| 8 | Inhibitory effect of osthole on alcohol-induced fatty liver in mice显示文摘 | Sun F Xie ML Zhu U | 2009 | Dig Liver Dis2009，41，： | 1 |
| 9 | Treatment of agricultural wastewater in a combined tidal flow-down flow reed bed system显示文摘 | Sun U Cray K R Biddlestone A J | 1999 | Water Science and Technology1999，40，3： | 1 |
| 10 | Peroxiredoxin I is an indicator of microglia activation and protects against hydrogen peroxide-mediated microglial death显示文摘 | Kim S U Hwang C N Sun H N | 2008 | Biol Pharm Bull2008，31，5： | 1 |
| 11 | Fixation, not death,reduces sensitivity of DTI in detecting optic nerve damage显示文摘 | Sun S W Liang H F Xie M Oyoyo U Lee A | 2009 | Neuroimage2009，44，： | 1 |
| 12 | Application of solidified floating organic drop microextraction method for biomonitoring of chlorpyrifos and its oxon metabolite in urine samples显示文摘 | Füsun Ok?u Pelit ?i?dem Yengin | 2014 | Journal of Chromatography B2014，，： | 1 |
| 13 | 显示文摘 | Liu Wenjian Sun Baozhong H u Hong | 2007 | Polymer Composites2007，28，2： | 1 |
| 14 | Silver/dendrimer nanocom-posites as biomarkers:fabrication,characterization,in vitro toxicity,andintracellular detection显示文摘 | LESNIAK W BIELINSKA A U SUN K | 2005 | Nano Lett2005，5，11： | 1 |
| 15 | Silver/dendrimer nanocomposites as biomarkers:fabrication,characterization,in vitro toxicity,and intracellular detection显示文摘 | LESNIAK W BIELINSKA A U SUN K | 2005 | Nano Lett2005，5，： | 1 |
| 16 | Silver/ dendrimer nanocomposites as biomarkers: Fabrication, characterization, in vitro toxicity, and intracellular detection 显示文摘 | Lesniak W Bielinska A U Sun K | 2005 | Nano Lett2005，5，11： | 1 |
| 17 | Silver/dendrimer nanocomposites as biomarkers : fabrication, characterization, in vitro toxicity, and tntracellular detection 显示文摘 | Lesniak W Bielinska A U Sun K | 2005 | Nano Letters2005，5，11： | 1 |
| 18 | Background suppression based-on wavelet transformation to detect infrared target显示文摘 | Sun Y U Tian J in-Wen | 2005 | International Conference on Machine Learning and Cybernetics2005，，： | 1 |
| 19 | Comparative affects of plasmid-encoded interleukin 12 and interleukin 18 on the protective efficacy of DNA vaccination against Mycobacterium tuberculosis 显示文摘 | Triccas J A Sun L Palendira U | 2002 | Immunol Cell Biol2002，80，4： | 1 |
| 20 | Multiple description coding with prediction compensation 显示文摘 | SUN G SAMARAWICKRAMA U LIANG J | 2009 | IEEE Transaction-ns on Image Processing2009，18，5： | 1 |
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