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| 1 | RT instability in cylindrical implosion of jelly ring显示文摘 | Yang Libing Liao Haidong Sun Chenwei | 2004 | Chin Phys2004，13，10： | 1 |
| 2 | New cyclopiane diterpenes with anti-inflammatory activity from the sea sediment-derived fungus Penicillium sp.TJ403-2显示文摘Three new rare cyclopiane diterpenes(1-3),together with thirteen known compounds(4-16),were isolated and identified from a sea sediment-derived fungus Penicillium sp.TJ403-2.The planar and relative structures of compounds 1-3 were elucidated by HRESIMS,one-and two-dimensional NMR analyses,and their absolute configurations were further established by X-ray crystallography experiment.Compounds 1-3 were evaluated for the anti-inflammatory activity against LPS-induced NO production,and compound 1 showed notable inhibitory potency with an IC50 value of2.19±0.25μmol/L,which was three fold lower than the positive control indomethacin(IC50=8.76±0.92μmol/L).Further Western blot and immunofluorescence experiments demonstrated its mechanism of action to be that 1 inhibited the NF-κB-activated pathway,highlighting it as a promising starting point for the development of new anti-inflammatory agents. | Fengli Li Weiguang Sun Sitian Zhang Weixi Gao Shuang Lin Beiye Yang Chenwei Chai Huaqiang Li Jianping Wang Zhengxi Hu Yonghui Zhang | 2020 | Chinese Chemical Letters2020，31，1： | 1 |
| 3 | Synthesis of two new thiazolidines and their hepatoprotective effects显示文摘Two new 2-substituted thiazolidine-4(R)-carboxylic acids (TCAs), 2-glusosaminal-TCA (GlcNH2Cys) and 2-N-acetyl-glucosaminal-TCA (GlcNAcCys), were synthesized. Their protective effects against liver toxicity induced by acetaminophen (APAP) were investigated in a mice model. The results demonstrate that administration of TCAs (i.p., 800 mg/kg) 30 min after APAP challenge efficiently decrease ALT, AST, and LDH levels in liver. GlcNAcCys shows the best protective effects, decreasing ALT, AST and LDH levels to 63%, 18.4% and 37% of the APAP group respectively. Comparison with the control showed that APAP greatly decreases total sulfhydryl (T-SH) levels (43%), non-protein bound sulfhydryl (NP-SH) levels (50%) and total antioxidative capabilities (57%) in the liver 24 hr after challenge. TCAs treatments 30 min after APAP challenge significantly elevate sulfhydryl levels and total antioxidative capabilities. APAP administration also markedly (P<0.05) increases liver lipid peroxidation to 1.65 and 1.17 times that of the control 4 hr and 24 hr after APAP administration respectively. TCAs treatments can inhibit lipid peroxidation as measured by decreased malondialdehyde (MDA) contents in liver. The histopathological results also further confirm the hepatoprotective effects of TCAs. In conclusion, our data show that TCAs, GlcNAcCys particularly, have hepatoprotective and antioxidant effects. | 杨艳 Liu Wanshun Han Baoqin Fu Chenwei Sun Haizhou | 2005 | High Technology Letters2005，11，4： | 1 |
| 4 | Electroluminescence from ITO/SiO 2 /Ta 2 O 5 /Al multiple-layer structure excited by hot electrons显示文摘 | Jiaming Sun Guozhu Zhong Xiwu Fan Guozhu Fu Chenwei Zheng | 1997 | Journal of Non-Crystalline Solids1997，，2： | 1 |
| 5 | A patient with glucocorticoid hypersensitivity syndrome显示文摘To the Editor:Primary generalized glucocorticoid hypersensitivity is a rare condition characterized by generalized,partial target-tissue hypersensitivity to glucocorticoids.Therefore,low concentration of glucocorticoids is sufficient to effectively maintain the patient’s cell physiological effects and to suppress the hypothalamic-pituitary-adrenal axis.Our study aims to provide some insight into when glucocorticoid hypersensitivity should be considered and how to diagnose it.We also propose a diagnostic flow chart for glucocorticoid hypersensitivity for the first time based on our experience and previous literature review.The study was reviewed and approved by the Institutional Review Board of Huashan Hospital,Fudan University(No.KY2020-049). | Chenwei Wu Anran Ma Quanya Sun Xiaolong Zhao | 2022 | Chinese Medical Journal2022，135，21： | 0 |
| 6 | Good pregnancy prognosis for a woman with panhypopituitarism显示文摘 | Fu Chenwei Liu Juntao Yang Jianqiu Sun Zhenyi Yu Xin | 2014 | Chinese Medical Journal2014，，13： | 0 |
| 7 | Visualizing the role of applied voltage in non-metal electrocatalysts显示文摘Understanding how applied voltage drives the electrocatalytic reaction at the nanoscale is a fundamental scientific problem,particularly in non-metallic electrocatalysts,due to their low intrinsic carrier concentration.Herein,using monolayer molybdenum disulfide(MoS_(2))as a model system of non-metallic catalyst,the potential drops across the basal plane of MoS_(2)(△V_(sem))and the electric double layer(△V_(edl))are decoupled quantitatively as a function of applied voltage through in-situ surface potential microscopy.We visualize the evolution of the band structure under liquid conditions and clarify the process of EF keeping moving deep into Ec,revealing the formation process of the electrolyte gating effect.Additionally,electron transfer(ET)imaging reveals that the basal plane exhibits high ET activity,consistent with the results of surface potential measurements.The potential-dependent behavior of kf and ns in the ET reaction are further decoupled based on the measurements of△V_(sem)and△V_(edl).Comparing the ET and hydrogen evolution reaction imaging results suggests that the low electrocatalytic activity of the basal plane is mainly due to the absence of active sites,rather than its electron transfer ability.This study fills an experimental gap in exploring driving forces for electrocatalysis at the nanoscale and addresses the long-standing issue of the inability to decouple charge transfer from catalytic processes. | Ziyuan Wang Jun Chen Chenwei Ni Wei Nie Dongfeng Li Na Ta Deyun Zhang Yimeng Sun Fusai Sun Qian Li Yuran Li Ruotian Chen Tiankai Bu Fengtao Fan Can Li | 2023 | National Science Review2023，10，9： | 0 |
| 8 | Romantic Qixi Festival in Wuhan显示文摘Marriage registration At this year's Qixi Festival,982 couples in Wuhan received their marriage certificates.The Civil Affairs Bureau marriage registration offices carefully arranged a traditional and romantic ceremony for the newly licensed couples.At the marriage office in Jiang'an District,red lanterns were hung up and a wall of balloons was set up for phototaking. | Sun Jun Huang Lijuan Liu Chenwei | 2022 | Changjiang Weekly2022，，31： | 0 |
| 9 | Tailoring morphology symmetry of bismuth vanadate photocatalysts for efficient charge separation显示文摘Although spatial charge separation between different facets of semiconductor crystals has been recognized as a general strategy in photocatalysis, the vital role of crystal morphology symmetry in charge separation properties still remains elusive. Herein,taking monoclinic bismuth vanadate(BiVO_(4)) as a platform, we found distinct charge separation difference via rationally tailoring the morphology symmetry from octahedral to truncated octahedral crystals. For octahedral BiVO_(4), photogenerated electrons and holes can be separated between edges and quasi-equivalent facets. However, as for truncated octahedral crystals,photogenerated electrons tend to transfer to {010} facets while photogenerated holes prefer to accumulate on {120} facets, thus realizing the spatial separation of photogenerated charge between different facets. Morphology tailoring of BiVO_(4) crystals leads to a significantly improved photogenerated charge separation efficiency and photocatalytic water oxidation activity. The built-in electric field for driving the separation of photogenerated electrons and holes is considered to be modulated by tuning the morphology symmetry of BiVO_(4) crystals. This work discloses the significant roles of morphology symmetry in photogenerated charge separation and facilitates the rational design of artificial photocatalysts. | Yuting Deng Hongpeng Zhou Chenwei Ni Fengke Sun Wenchao Jiang Ruotian Chen Wenming Tian Can Li Rengui Li | 2023 | Science China Chemistry2023，66，12： | 0 |
| 10 | Tip-induced directional charge separation on one-dimensional BiVO4 nanocones for asymmetric light absorption显示文摘One dimensional(1D)semiconductor is a class of extensively attractive materials for many emerging solar energy conversion technologies.However,it is still of shortage to assess the impact of 1D structural symmetry on spatial charge separation and understand its underlying mechanism.Here we take controllably-synthesized 1D BiVO_(4)nanocones and nanorods as prototypes to study the influence of 1D symmetry on charge separation.It is found that the asymmetric BiVO_(4)nanocones enable more effective charge separation compared with the symmetric nanorods.The unexpected spatial charge separation on the nanocones is mainly ascribed to uneven light absorption induced diffusion-controllable charge separation due to symmetry breaking of 1D nanostructure,as evidenced by spatial and temporal resolved spectroscopy.Moreover,the promotion effect of charge separation on the nanocones was quantitatively evaluated to be over 20 times higher than that in BiVO_(4)nanorods.This work gives the first demonstration of the influence of 1D structural symmetry on the charge separation behavior,providing new insights to design and fabricate semiconductor materials for efficient solar energy conversion. | Nengcong Yang Ruotian Chen Chenwei Ni Dongfeng Li Qi Sun Lifang Liu Yu Qi Shengye Jin Xiuli Wang Fengtao Fan Can Li Fuxiang Zhang | 2022 | Journal of Energy Chemistry2022，31，9： | 0 |
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