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| 1 | Cancer incidence,mortality,and burden in China:a time-trend analysis and comparison with the United States and United Kingdom based on the global epidemiological data released in 2020显示文摘Background:Cancer is one of the leading causes of death and a main economic burden in China.Investigating the differences in cancer patterns and control strategies between China and developed countries could provide reference for policy planning and contribute to improving cancer control measures.In this study,we reviewed the rates and trends of cancer incidence and mortality and disability-adjusted life year(DALY)burden in China,and compared them with those in the United States(US)and the United Kingdom(UK).Methods:Cancer incidence,mortality,and DALY data for China,US and UK were obtained fromtheGLOBOCAN2020 online database,Global Burden of Disease(GBD)2019 study,and Cancer Incidence in Five Continents plus database(CI5 plus).Trends of cancer incidence and mortality in China,US,and UK were analyzed using Joinpoint regression models to calculate annual percent changes(APCs)and identify the best-fitting joinpoints.Results:An estimated 4,568,754 newly diagnosed cancer cases and 3,002,899 cancer deaths occurred in China in 2020.Additionally,cancers resulted in 67,340,309 DALYs in China.Compared to the US and UK,China had lower cancer incidence but higher cancer mortality andDALY rates.Furthermore,the cancer spectrum of China was changing,with a rapid increase incidence and burden of lung,breast,colorectal,and prostate cancer in addition to a high incidence and heavy burden of liver,stomach,esophageal,and cervical cancer.Conclusions:The cancer spectrum of China is changing from a developing country to a developed country.Population aging and increase of unhealthy lifestyles would continue to increase the cancer burden of China.Therefore,the Chinese authorities should adjust the national cancer control program with reference to the practices of cancer control which have been well-established in the developed countries,and taking consideration of the diversity of cancer types by of different regions in China at the same time. | Haibo Qiu Sumei Cao Ruihua Xu | 2021 | Cancer Communications2021，41，10： | 194 |
| 2 | Functional analysis of alternative splicing of the FLOWERING LOCUS T orthologous gene in Chrysanthemum morifolium显示文摘As the junction of floral development pathways,the FLOWERING LOCUS T(FT)protein called‘florigen’plays an important role in the process of plant flowering through signal integration.We isolated four transcripts encoding different isoforms of a FT orthologous gene CmFTL1,from Chrysanthemum morifolium cultivar‘Jimba’.Sequence alignments suggested that the four transcripts are related to the intron 1.Expression analysis showed that four alternative splicing(AS)forms of CmFTL1 varied depending on the developmental stage of the flower.The functional complement experiment using an Arabidopsis mutant ft-10 revealed that the archetypal and AS forms of CmFTL1 had the function of complementing late flower phenotype in different levels.In addition,transgenic confirmation at transcript level showed CmFTL1 and CmFTL1ast coexist in the same tissue type at the same developmental stage,indicating a post-transcriptional modification of CmFTL1 in Arabidopsis.Moreover,ectopic expression of different AS forms in chrysanthemum resulted in the development of multiple altered phenotypes,varying degrees of early flowering.We found that an alternative splicing form(CmFTL1-astE134)without the exon 2 lacked the ability causing the earlier flower phenotype.The evidence in this study indicates that complex alternative processing of CmFTL1 transcripts in C.morifolium may be associated with flowering regulation and hold some potential for biotechnical engineering to create early-flowering phenotypes in ornamental cultivars. | Yachao Mao Jing Sun Peipei Cao Rong Zhang Qike Fu Sumei Chen Fadi Chen Jiafu Jiang | 2016 | Horticulture Research2016，3，1： | 7 |
| 3 | Seasonal variations of particulate silicon in the Changjiang (Yangtze River) Estuary and its adjacent area显示文摘Temporal and spatial distribution of biogenic (BSi) and lithogenic (LSi) silica were studied in the Changjiang (Yangtze River) Estuary and its adjacent area. The annual average BSi and LSi concentrations were (1.71 ± 1.79) μmol/L and (0.56 ± 1.41) mmol/L, respectively. Both BSi and LSi were high in the inshore areas, where they received terrigenous discharge from the Changjiang, and decreased towards the offshore region. BSi and LSi were most abundant at the near bottom layer due to the high sedimentation rates and resuspension of sediment. Diatom blooms occurred in summer with high Chl a concentration in the surface layer, which induced that BSi in the surface layer during summer was obviously higher than that in the surface layer of other seasons. LSi concentration was maximal in autumn and spring and minimum in summer, associated with the seasonal variation of SPM values. Drifting investigation and mesocosm experiments were conducted during dinoflagellate bloom, aiming to understand the effect of nutrients on BSi by changing the phytoplankton composition. The results show that the low dissolved inorganic phosphorus concentration and high molar ratio of N/P (dissolved inorganic nitrogen vs. dissolved inorganic phosphorus), were the important factors for decreasing diatom biomass in the study area, and it would subsequently decrease the BSi concentration in aquatic ecosystem. | CAO Lu LIU Sumei REN Jingling | 2013 | Acta Oceanologica Sinica2013，32，4： | 3 |
| 4 | Crystal facet-dependent electrocatalytic performance of metallic Cu in CO_(2)reduction reactions显示文摘Developing high-performance electrocatalysts for CO_(2) reduction reaction(CO_(2)RR)is crucial since it is beneficial for environmental protection and the resulting value-add chemical products can act as an alternative to fossil feedstocks.Nonetheless,the direct reduction of CO_(2) into long-chain hydrocarbons and oxygenated hydrocarbons with high selectivity remains challenging.Copper(Cu)shows a distinctive advantage that it is the only pure metal catalyst for reducing CO_(2) into multi-carbon(C_(2+))products and the certain facets(e.g.,(100),(111),(111))of Cu nanocrystals exhibit relatively low energy barriers for the formation of specific products(e.g.,CO,HCOOH,CH_(4),C_(2)H_(4),C_(2)H_(5)OH,and other C_(2+) products).Therefore,extensive studies have been carried out to explore the relationship between the facets of Cu nanocrystals and corresponding catalytic products.In this review,we will discuss the crystal facet-dependent electrocatalytic CO_(2)RR performance in metallic Cu catalysts,meanwhile,the detailed reaction mechanisms will be systematically summarized.In addition,we will provide a personal perspective for the future research directions in this emerging field.We believe this review is helpful to guide the design of high-selectivity Cu-based electrocatalysts for CO_(2)RR. | Hao Zhang Caihong He Sumei Han Zeyang Du Ling Wang Qinbai Yun Wenbin Cao Bowei Zhang Ya-Hui Tian Qipeng Lu | 2022 | Chinese Chemical Letters2022，33，8： | 2 |
| 5 | Thermal cycling behavior and failure mechanism of La 2 (Zr 0.7 Ce 0.3 ) 2 O 7 /Eu 3+ -doped 8YSZ thermal barrier coating prepared by atmospheric plasma spraying显示文摘 | Sumei Zhao Lijian Gu Yu Zhao Wenzhi Huang Ling Zhu Xizhi Fan Binglin Zou Xueqiang Cao | 2013 | Journal of Alloys and Compounds2013，，： | 1 |
| 6 | Reactive plasma spraying synthesis and characterization of TiB 2 –TiC–Al 2 O 3 /Al composite coatings on a magnesium alloy显示文摘 | Jiaying Xu Binglin Zou Xizhi Fan Sumei Zhao Yu Hui Ying Wang Xin Zhou Xiaolong Cai Shunyan Tao Hongmei Ma Xueqiang Cao | 2014 | Journal of Alloys and Compounds2014，，： | 1 |
| 7 | γδ T cells recognize tumor cells via CDR3δ region显示文摘 | Chunping Xu Huiyuan Zhang Hongbo Hu Hongbin He Zhun Wang Yong Xu Hui Chen Wei Cao Sumei Zhang Lianxian Cui Denian Ba Wei He | 2006 | Molecular Immunology2006，，4： | 1 |
| 8 | Regulation of bone phosphorus retention and bone development possibly by related hormones and local bone-derived regulators in broiler chicks显示文摘Background:Phosphorus is essential for bone mineralization in broilers,however,the underlying mechanisms remain unclear.We aimed to investigate whether bone phosphorus retention and bone development might be regulated by related hormones and local bone-derived regulators in broilers.Methods:Broilers were fed diets containing different levels of non-phytate phosphorus(NPP)0.15%,0.25%,0.35%,0.45% and 0.55% or 0.15%,0.22%,0.29%,0.36% and 0.43% from 1 to 21 or 22 to 42 days of age.Serum and tibia samples were collected for determinations of bone phosphorus retention and bone development parameters,related hormones and local bone-derived regulators of broiler chickens on d 14,28 and 42,respectively.Results:Tibia ash phosphorus,total phosphorus accumulation in tibia ash(TP_(TA)),bone mineral concentration(BMC),bone mineral density(BMD),bone breaking strength(BBS),and ash on d 14,28 or 42,serum 1,25-dihydroxyvitamin D_(3)(1,25(OH)_(2)D_(3))on d 28 and 42,mRNA expressions of tibia fibroblast growth factor 23(FGF23)and dentin matrix protein 1(DMP1)on d 14 and 28 increased linearly or quadratically(P<0.05),while serum parathyroid hormone(PTH)on d 28,tibia alkaline phosphatase(ALP)on d 14,28 and 42,bone gal protein(BGP)on d 14,and mRNA expression of tibia phosphate-regulating gene with homologies to endopeptidases on the X chromosome(PHEX)on d 14 and 28 decreased linearly or quadratically(P<0.04)as dietary NPP level increased.TPTA,BMC,BMD,and ash on d 28 and 42,BBS on d 28,and ash phosphorus on d 42 were positively correlated(r=0.389 to 0.486,P<0.03)with serum 1,25(OH)_(2)D_(3).All of the above parameters were positively correlated(r=0.380 to 0.689,P<0.05)with tibia DMP1 mRNA expression on d 14,28 and 42,but negatively correlated(r=−0.609 to−0.538,P<0.02)with serum PTH on d 28,tibia ALP on d 14,28 and 42,and BGP on d 14.TP_(TA),BMC and ash on d 14 and BMD on d 28 were negatively correlated(r=−0.397 to−0.362,P<0.03)with tibia PHEX mRNA expression,and BMD on d 28 was positively correlated(r=0.384,P=0.04)with tibia FGF23 mRNA expression.Conclusions:These results suggested that bone phosphorus retention and bone development parameters had moderate to strong correlations with serum PTH and 1,25(OH)2D3 and tibia DMP1,PHEX,FGF23,ALP and BGP in broilers during the whole growth period,and thus they might be partly regulated by these related hormones and local bone-derived regulators. | Sumei Cao Tingting Li Yuxin Shao Liyang Zhang Lin Lu Rijun Zhang Shuisheng Hou Xugang Luo Xiudong Liao | 2022 | Journal of Animal Science and Biotechnology2022，13，1： | 1 |
| 9 | Self-propagating high-temperature synthesis of TiC–TiB 2 -based Co cermets from a Co–Ti–B 4 C system and fabrication of coatings using the cermet powders显示文摘 | Binglin Zou Jiaying Xu Ying Wang Sumei Zhao Xizhi Fan Yu Hui Xin Zhou Wenzhi Huang Xiaolong Cai Shunyan Tao Hongmei Ma Xueqiang Cao | 2013 | Chemical Engineering Journal2013，，： | 1 |
| 10 | Configuration and Setting of Protections for Wind Farm Collector System显示文摘Compared with traditional synchronous generators, wind turbine generators are different in electricity generation principles, control modes and integration topologies, which makes their fault characteristics change a lot. This, consequently, brings challenges regarding the behavior of protections for wind farm collector systems. In this paper, based on a practical wind farm, configuration and setting of relay protections for such a collector system is analyzed and determined systematically in consideration of the selectivity and sensitivity of the protections. Results show that misoperation of overcurrent relay and zero sequence overcurrent relay of the non-fault collector line occurs, and bus differential relay of collector bus cannot remove the single-phase-to-ground fault. In order to solve the problems, a novel substation-area protection for collector system is proposed and its operation mechanism is discussed. | Li Yanbin Zhang Li Bi Tianshu Cao Hong Liu Sumei | 2014 | Electricity2014，25，5： | 0 |
| 11 | Introducing oxygen vacancies in TiO_(2) lattice through trivalent iron to enhance the photocatalytic removal of indoor NO显示文摘The synthesis of oxygen vacancies(OVs)-modified TiO_(2)under mild conditions is attractive.In this work,OVs were easily introduced in TiO_(2)lattice during the hydrothermal doping process of trivalent iron ions.Theoretical calculations based on a novel charge-compensation structure model were employed with experimental methods to reveal the intrinsic photocatalytic mechanism of Fe-doped TiO_(2)(Fe-TiO_(2)).The OVs formation energy in Fe-TiO_(2)(1.12 eV)was only 23.6%of that in TiO_(2)(4.74 eV),explaining why Fe^(3+)doping could introduce OVs in the TiO_(2)lattice.The calculation results also indicated that impurity states introduced by Fe^(3+)and OVs enhanced the light absorption activity of TiO_(2).Additionally,charge carrier transport was investigated through the carrier lifetime and relative mass.The carrier lifetime of Fe-TiO_(2)(4.00,4.10,and 3.34 ns for 1at%,2at%,and 3at%doping contents,respectively)was longer than that of undoped TiO_(2)(3.22 ns),indicating that Fe^(3+) and OVs could promote charge carrier separation,which can be attributed to the larger relative effective mass of electrons and holes.Herein,Fe-TiO_(2)has higher photocatalytic indoor NO removal activity compared with other photocatalysts because it has strong light absorption activity and high carrier separation efficiency. | Peng Sun Sumei Han Jinhua Liu Jingjing Zhang Shuo Yang Faguo Wang Wenxiu Liu Shu Yin Zhanwu Ning Wenbin Cao | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，10： | 0 |
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