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| 1 | Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable?显示文摘AIM: To establish the diagnostic performance of sev-eral serological tests, individually and in combination, for diagnosing celiac disease (CD) in patients with different pretest probabilities, and to explore potential se- rological algorithms to reduce the necessity for biopsy. METHODS: We prospectively performed duodenal biopsy and serology in 679 adults who had either high risk (n = 161) or low risk (n = 518) for CD. Blood samples were tested using six assays (enzyme-linked immunosorbent assay) that detected antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP). RESULTS: CD prevalence was 39.1% in the high-risk population and 3.3% in the low-risk group. In high-risk patients, all individual assays had a high diagnostic efficacy [area under receiving operator characteristic curves (AU ROC): 0.968 to 0.999]. In contrast, assays had a lower diagnostic efficacy (AU ROC: 0.835 to 0.972) in the low-risk group. Using assay combinations, it would be possible to reach or rule out diagnosis of CD without biopsy in 92% of cases in both pretest populations. We observed that the new DGP/tTG Screen assay resulted in a surplus compared to more conventional assays in any clinical situation. CONCLUSION: The DGP/tTG Screen assay could be considered as the best initial test for CD. Combinations of two tests, including a DGP/tTG Screen, might be able to diagnose CD accurately in different clinical scenarios making biopsy avoidable in a high proportion of subjects. | Emilia Sugai María L Moreno Hui J Hwang Ana Cabanne Adriana Crivelli Fabio Nach-man Horacio Vázquez Sonia Niveloni Julio Argonz Roberto Mazure Graciela La Motta María E Caniggia Edgardo Smecuol Néstor Chopita Juan C Gómez Eduardo Maurińo Julio C Bai | 2010 | World Journal of Gastroenterology2010，16，25： | 4 |
| 2 | Uncertainty about Government Policy and Stock Prices显示文摘 | L?UBOS? PáSTOR PIETRO VERONESI | 2012 | The Journal of Finance2012，，4： | 3 |
| 3 | Percutaneous fixation of displaced proximal humeral fractures: Indications based on the correlation between clinical and radiographic results显示文摘 | Emilio Calvo Ignacio de Miguel Juan J. de la Cruz Néstor López-Martín | 2007 | Journal of Shoulder and Elbow Surgery2007，，6： | 2 |
| 4 | Use of wild trout for PBDE assessment in freshwater environments: Review and summary of critical factors显示文摘Certain wild animals represent sentinels to address issues related to environmental pollution,since they can provide integrative data on both pollutant exposure and biological effects.Despite their technological benefits,PBDEs are considered a threat to environmental health due to their persistence,toxicity,and capacity to be accumulated.These pollutants have been found geographically widespread in fish,particularly in predator species such as trout.The aim of this work is to critically review the applicability and usefulness of wild trout for assessing PBDEs in freshwater environments.Reviewed reports include data from highly industrialized areas as well as areas from remote regions with relatively low human activity,including European and North American great lakes and freshwater environments in Europe,Greenland,subarctic areas and Patagonia,respectively.A summary of relevant factors were grouped into organism-specific factors(food habits,age,size,lipid content,sex and reproduction,tissue type,mechanism of contaminant uptake and metabolism),and PBDE levels in the surrounding environment(sediment).Five wild trout species[rainbow trout(Oncorhynchus mykiss),brown trout(Salmo trutta),lake trout(Salvelinus namaycush),arctic char(Salvelinus alpinus),and brook trout(Salvelinus fontinalis)],collected worldwide within the 1994 to present time frame,were considered.Multivariate techniques(principal component analysis-PCA)and mapping approach,showed clear differences in geographic distribution patterns of PBDE levels in trout depending on the region studied:wild trout from European and North American great lakes have the highest PBDE loads.This pattern could be due to high industrial activity at these locations.A correlational approach used to explore intraspecific relationships between PBDE levels and morphometry,showed positive relationships only for brown trout.Further,brown trout showed the highest trout-to-sediment ratios,which is suggestive of a relatively greater capacity of this species to accumulate PBDEs in relation to sediment levels.Overall,results suggest that adult wild trout could be useful as a PBDE bioindicator. | Juan M.Ríos Nerina B.Lana Paula Berton Néstor F.Ciocco Jorgelina C.Altamirano | 2015 | Emerging Contaminants2015，1，1： | 2 |
| 5 | The International Standard for Pituitary FSH: collaborative study of the standard and of four other purified human FSH preparations of differing molecular composition by bioassays,receptor assays and different immunoassay systems显示文摘 | Storring PL Gaines Das RE | 1989 | J Endocrinol1989，123，2： | 1 |
| 6 | Generation of superoxide anion in chloroplasts of Arabidopsis thaliana during active photosynthesis: a focus on rapidly induced genes显示文摘 | Telma E. Scarpeci María I. Zanor Néstor Carrillo Bernd Mueller-Roeber Estela M. Valle | 2008 | Plant Molecular Biology2008，，4： | 1 |
| 7 | Mechanisms controlling leaf retention of agricultural spray solutions显示文摘 | WIRTH W STOR S JACOBSEN W | | 0，，04： | 1 |
| 8 | Transcriptional regulator of oxidative stress induce gen- es: Directiot activation by oxidation显示文摘 | Taraglia LA Ames B | 1990 | Science1990，248，1： | 1 |
| 9 | Political uncertainty and risk premia显示文摘 | ?ubo? Pástor Pietro Veronesi | 2013 | Journal of Financial Economics2013，，3： | 1 |
| 10 | Outcome after emergency subtotal/total colectomy compared to elective resection in patients with left-sided colorectal carcinoma显示文摘 | Omejc M Stor Z Jelenc F | 1998 | Int Surg1998，83，3： | 1 |
| 11 | Design and validation of the high performance and low noise CQU‐DTU‐LN1 airfoils显示文摘 | Jiangtao Cheng Weijun Zhu Andreas Fischer Néstor Ramos García Jesper Madsen Jin Chen Wen Zhong Shen | 2014 | Wind Energ2014，，12： | 1 |
| 12 | Design, process and charaeterisation of a high-performance vibration sensor for wireless condition monitoring 显示文摘 | VOGL A WANG D T STOR? S P | 2009 | Sensors and Actuators A: Physical2009，153，2： | 1 |
| 13 | Relationships between the N-glycan structures and biological activities of recombinant human erythropoietins produced using different cuhure conditions and purification procedures显示文摘 | Yuen CT Storring PL Tiplady RJ | 2003 | Br J Haematol2003，121，： | 1 |
| 14 | Mutual fund performance and seemingly unrelated assets显示文摘 | Pástor L Stambaugh R.F | | 0，，03： | 1 |
| 15 | Physicochemical methods for predicting the biological potency of recombinant follicle stimulating hormone:an international collaborative study of isoelectric focusing and capillary zone electrophoresis显示文摘 | Storring PL Gaines Das RE Mulders JW | 2002 | Biologicals2002，30，3： | 1 |
| 16 | Repair of bile duct injuries with gore-tex vascular grafts: Experimental study in dogs显示文摘 | Néstor A. Gómez M.D. F.A.C.S. F.A.C.G. Ludwig R. Alvarez M.D. Alfredo Mite V.D. Jean P. Andrade M.D. José R. Alvarez M.D. Paola E. Vargas M.D. Nancy E. Tomalá M.D. Alex F. Vivas M.D. Jorge A. Zapatier | 2002 | Journal of Gastrointestinal Surgery2002，，1： | 1 |
| 17 | Sonochemical and sonophotocatalytic degradation of malachite green:The effect of carbon tetrachloride on reaction rates显示文摘 | Néstor Javier Bejarano-Pérez Marco Fidel Suárez-Herrera | 2008 | Ultrasonics Sonochemistry2008，15，4： | 1 |
| 18 | Epoetin alfa and beta differ in their erythropoietin isoform compositions and biological properties显示文摘 | Storring Tiplady Gaines D | 1998 | Br J Haematol1998，100，： | 1 |
| 19 | Epoetin alfa and beta differ in their erytbropoietin isoform compositions and biological properties 显示文摘 | STORRING PL TIPLADY R J GAIES DAS RE | 1998 | British J Haematol1998，100，1： | 1 |
| 20 | Stock Valuation and Learning about Profitability显示文摘 | ?ubo?Pástor VeronesiPietro | 2003 | The Journal of Finance2003，，5： | 1 |
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