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| 1 | LPS对BALB/C小鼠肾小管上皮细胞TLR4和TNFα、IL-6表达的影响显示文摘目的探讨TLR4在BALB/C小鼠肾小管上皮细胞(TEC)的表达和内毒素/脂多糖(LPS)刺激后TLR4的变化,以及对产生肿瘤坏死因子α(TNFα)、白细胞介素-6(IL-6)的影响。方法通过RT-PCR方法检测TLR4 mRNA、TNFαm RNA和IL-6 mRNA在TEC的表达;流式细胞术检测TEC的TLR4膜蛋白水平;ELISA检测培养的TEC上清中TNFα、IL-6的含量。结果正常TEC有TLR4 mRNA表达,但TNFα mRNA、IL-6 mRNA表达甚弱。经LPS刺激后,TEC中的TLR4 mRNA、TNFα mRNA和IL-6 mRNA表达均显著增强,TLR4膜蛋白以及培养上清中的TNFα、IL-6水平亦相应增加。结论TLR4在LPS激活的TEC中表达显著增强,同时TEC分泌的炎症因子TNFα、IL-6的水平也相应上调。 | 朱晓玲 Li Ke 王永钧 杨亚珍 Wuding Zhou Steven Sacks | 2008 | 医学研究杂志2008，37，1： | 5 |
| 2 | Tailored PEDOT:PSS hole transport layer for higher performance in perovskite solar cells: Enhancement of electrical and optical properties with improved morphology显示文摘Precise control over the charge carrier dynamics throughout the device can result in outstanding performance of perovskite solar cells(PSCs).Poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate)(PEDOT:PSS)is the most actively studied hole transport material in p-i-n structured PSCs.However,charge transport in the PEDOT:PSS is limited and inefficient because of its low conductivity with the presence of the weak ionic conductor PSS.In addition,morphology of the underlying PEDOT:PSS layer in PSCs plays a crucial role in determining the optoelectronic quality of the active perovskite absorber layer.This work is focused on realization of a non-wetting conductive surface of hole transport layer suitable for the growth of larger perovskite crystalline domains.This is accomplished by employing a facile solventengineered(ethylene glycol and methanol)approach resulting in removal of the predominant PSS in PEDOT:PSS.The consequence of acquiring larger perovskite crystalline domains was observed in the charge carrier dynamics studies,with the achievement of higher charge carrier lifetime,lower charge transport time and lower transfer impedance in the solvent-engineered PEDOT:PSS-based PSCs.Use of this solventengineered treatment for the fabrication of MAPbI3 PSCs greatly increased the device stability witnessing a power conversion efficiency of 18.18%,which corresponds to^37%improvement compared to the untreated PEDOT:PSS based devices. | Khan Mamun Reza Ashim Gurung Behzad Bahrami Sally Mabrouk Hytham Elbohy Rajesh Pathak Ke Chen Ashraful Haider Chowdhury Md Tawabur Rahman Steven Letourneau Hao-Cheng Yang Gopalan Saianand Jeffrey WElam Seth BDarling Qiquan Qiao | 2020 | Journal of Energy Chemistry2020，29，5： | 4 |
| 3 | BCL2 inhibits cell adhesion, spreading, and motility by enhancing actin polymerization显示文摘BCL2 最好作为多功能的 anti-apoptotic 蛋白质被知道。然而,很少在房间粘合剂和活动性事件对它的角色被知道。这里,我们证明 BCL2 可以在房间粘附的规定起一个作用,传播,并且活动性。BCL2 什么时候是在有教养的鼠科、人的房间线,传播的房间,粘附,和活动性的 overexpressed,被损害。与这些结果一致, Bcl2 的损失导致了在 Bcl2 空的老鼠观察的更高的活动性与野类型相比的胚胎的成纤维细胞(MEF ) 房间。房间粘附和活动性的 BCL2 规定的机制可以包含包含 BCL2,肌动朊,和 gelsolin 的建筑群的形成,它看起来机能上地减少 gelsolin 的切断的活动。我们观察到从 overexpressed BCL2 提高了的 MCF-7 和 NIH3T3 房间的 lysate 肌动朊聚合在在 vitro 试金没有房间。BCL2 和 F 肌动朊的共焦的 immunofluorescent 本地化在一致地传播期间证明 BCL2 的那增加的表情导致了增加的 F 肌动朊聚合。因此, BCL2 和 gelsolin 建筑群的形成(它可能包含另外的蛋白质) 看起来在房间粘附和移植的规定起一个关键作用。与癌症转移给房间活动性的确定的关联,这结果可以解释在一些肿瘤房间类型的 BCL2 的表示为什么为转移减少潜力并且与改进耐心的预后被联系。 | Hengning Ke Vandy I Parron Jeff Reece Jennifer Y Zhang Steven K Akiyama John E French | 2010 | Cell Research2010，20，4： | 3 |
| 4 | Infection Burden for Hip and Knee Arthroplasty in the United States显示文摘 | Steven M. Kurtz Edmund Lau Jordana Schmier Kevin L. Ong Ke Zhao Javad Parvizi | 2008 | The Journal of Arthroplasty2008，，7： | 2 |
| 5 | Jeopardy, non-public information, and insider trading around SEC 10-K and 10-Q filings显示文摘 | Steven Huddart Bin Ke Charles Shi | 2007 | Journal of Accounting and Economics2007，43，： | 1 |
| 6 | A simple clinical scoring system to improve the sensitivity and standardization of the diagnosis of mycosis fungoides type cutaneous T-cell lymphoma:logistie re- gression of clinical and laboratory data 显示文摘 | Stevens SR Ke MS Birol A | 2003 | Br J Dermatol2003，149，3： | 1 |
| 7 | Antimicrobial tolerance and the signifieance of persister cells in recalcitrant chronic wound biofilms显示文摘 | Steven L Percival SL Hill KE | 2011 | Wound Repair Regen2011，19，1： | 1 |
| 8 | A simple clinical scoring systemto improve the sensitivity and standardization of the diagnosis of myco-sis fungoides type cutaneous T-cell lymphoma:logistic regression ofclinical and laboratory data显示文摘 | Stevens SR Ke MS Birol A | 2003 | Br J Dermatol2003，149，3： | 1 |
| 9 | The association of diabetes with breast cancer incidence and mortality in the Long Island Breast Cancer Study Project显示文摘 | Cleveland RJ North KE Stevens J | 2012 | Cancer Causes Control2012，23，7： | 1 |
| 10 | Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice显示文摘 | Stevens KE Kem WR Mahnir VM | | 0，，： | 1 |
| 11 | Jeopardy, non-public information, and insider trading around SEC 10-K and 10-Q filings显示文摘 | Steven Huddart Bin Ke Charles Shi | 2006 | Journal of Accounting and Economics2006，，1： | 1 |
| 12 | What insiders know about future earnings and how they use it: Evidence from insider trades显示文摘 | Bin Ke Steven Huddart Kathy Petroni | 2003 | Journal of Accounting and Economics2003，，3： | 1 |
| 13 | Oral immunization with recombinant listeria monocytogenes controls virus load after vaginal challenge with feline immunodeflciency virus 显示文摘 | Stevens R Howard KE Nordone S et at | 2004 | J Virol2004，78，15： | 1 |
| 14 | Polybrominated Diphenyl Ethers (PBDEs) and Bioaccumulative Hydroxylated PBDE Metabolites in Young Humans from Managua, Nicaragua显示文摘 | Athanasiadou Maria Cuadra Steven N Marsh G?ran Bergman ?ke Jakobsson Kristina | 2008 | Environmental Health Perspectives2008，，3： | 1 |
| 15 | Satellite based analysis of northern ET trends and associated changes in the regional water balance from 1983 to 2005显示文摘 | Ke Zhang John S. Kimball Qiaozhen Mu Lucas A. Jones Scott J. Goetz Steven W. Running | 2009 | Journal of Hydrology2009，，1： | 1 |
| 16 | Antimicrobial tolerance and the significance of persister eells in recalcitrant chronic wound biofilms显示文摘 | Steven L Percival SL Hill KE | 2011 | Wound Rep Reg2011，19，1： | 1 |
| 17 | Transcranial focal electrical stimulation via tripolar eorleentric ring electrodes does not modify the short- and long-term memory formation in rats evaluated in the novel object recognition test 显示文摘 | Rogel-Salazar G Luna-Munguia H Stevens KE | 2013 | EpilepsyBehav2013，27，1： | 1 |
| 18 | Maximising opportunities in supercritical chemistry:The continuous conversion of levulinic acid to gamma-valerolactone in CO2显示文摘 | Bourne R A Stevens J G Ke J | 2007 | Chemical Communications2007，，44： | 1 |
| 19 | Long-term results of Dana-Farber CancerInstitute ALLconsortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1985-2000)显示文摘 | Silverman LB Steven KE O'Brien JE Asselin BL Barr RD Clavell L | 2010 | Leukemia2010，24，2： | 1 |
| 20 | Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial显示文摘 | Gerald S Falchook Georgina V Long Razelle Kurzrock Kevin B Kim Tobias H Arkenau Michael P Brown Omid Hamid Jeffrey R Infante Michael Millward Anna C Pavlick Steven J O’Day Samuel C Blackman C Martin Curtis Peter Lebowitz Bo Ma Daniele Ouellet Richard F Ke | 2012 | The Lancet . 2012 (9829)2012，，9829： | 1 |
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