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| 1 | 乳汁免疫和猪流行性腹泻病毒病疫苗:历史和现状(译文)显示文摘由于肠道病毒感染导致仔猪在发病率、死亡率和生产能力丧失方面的影响,每年给养猪者带来数百万美元的损失。2013—2014年间,猪流行性腹泻病毒(PEDV)病的暴发给美国养猪业带来了9亿~18亿美元的经济损失。被动乳汁免疫被认为是保护新生哺乳仔猪免受PED等肠道疾病危害的最有希望和有效的方法。通过乳汁免疫被动保护哺乳仔猪的效果依赖于病原特异性IgA浆细胞转运至乳腺的数量和乳汁中分泌型IgA的积累程度,这种免疫途径被定义为'肠-乳腺-sIgA轴'。由于胎盘的不可穿透性,新生仔猪处于无免疫球蛋白的状态,对很多的传染性病原体极易感。它们仅依靠来源于母源的初乳和乳汁抗体获得被动保护。先前开发的关于猪传染性胃肠炎病毒(TGEV)病的活疫苗和灭活疫苗,提供了对母源性免疫和仔猪被动保护机制的理解。在这篇文章中,综述了猪传染性胃肠炎病毒诱导乳汁免疫的研究进展,并指出对当前养猪业正努力控制的猪流行性腹泻病毒感染和相关疫苗的研究方向。同时研究和鉴别出影响乳汁免疫和'肠-乳腺-sIgA轴'的各种因素,有助于改善妊娠母猪预防猪流行性腹泻病毒感染以及改进其它肠道病原用疫苗方案,从而达到提升整个猪群的免疫力、猪群健康和企业生产力的目的。 | Langel Stephanie N Paim Francine Chimelo Lager Kelly M Vlasova Anastasia N Saif Linda J 吕茂杰 | 2017 | 养猪2017，，1： | 3 |
| 2 | Physical activity and nutrition attitudes in obese Hispanic children with non-alcoholic steatohepatitis显示文摘AIM:To assess nutrition,physical activity and health-ful knowledge in obese children with biopsy-proven nonalcoholic steatohepatitis(NASH or NA)compared to children without liver disease.METHODS:Children with biopsy-proven NASH comprised the NASH group.Age,sex and ethnicity matched control groups consisted of obese(OB)and lean(CO) children with no liver disease.Subjects were adminis-tered the School Physical Activity and Nutrition Survey and one blood draw was obtained.RESULTS:Fifty-seven patients were enrolled with a mean age of 12.1±2.1 years,and all were Hispanic.Even though the OB and NA had a similar increased body mass index(%),35%of the NA group always read nutrition labels compared to none in the OB(P<0.05),and more NA children felt their diet is'less healthy'.NA consumed the least amount of fruits with only 25%having≥1 fruit/d vs 45%in OB and 64.7% in CO(P<0.05 NA vs CO).Only 15%of NA subjects performed light exercise vs 35%and 59%of OB and CO groups,respectively(P=0.02).The mean physical activity score was lowest in the NA group(P<0.05).Amongst the subjects with NASH,we found that 100% of patients with grade 2 or 3 fibrosis had a sedentary score>2 compared to only 63.6%of those with grade 1 or no fibrosis(P<0.05).CONCLUSION:Children with NASH had increased sedentary behavior,decreased activity,and fruit intake.Larger studies may determine the benefit of changing these behaviors as treatment for NASH. | Lana N Hattar Theresa A Wilson Leanel A Tabotabo E O'Brian Smith Stephanie H Abrams | 2011 | World Journal of Gastroenterology2011，17，39： | 2 |
| 3 | Bacterial RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited condition 显示文摘 | Paolo C Dave W Robert J B Don C A Jay H Martin S Mark A Ganesh K Sara S Robert D Santiago N Stephanie B Mary F Jayaprakash T Santanu D Christopher B Michael H L Jacqueline E H | 2008 | Plant Physiology2008，147，2： | 1 |
| 4 | Nutrition survey inan elderly population following admission to a tertiary care hospital显示文摘 | Azad N Murph JY Stephanie SA | 1999 | CMAJ1999，161，5： | 1 |
| 5 | Vascular effects of improving metabolic control with metformin or rosiglitazone in type 2 diabetes显示文摘 | Andrea N Daniele B Stephanie B | 2004 | Diabetes Care2004，27，： | 1 |
| 6 | Use of amino-terminal pro-B-type natriuretic peptide to guide outpatient therapy of patients with chronic left ventricular systolic dysfunction 显示文摘 | JAMES L JANUZZI JR MD SHAFIQ U REHMAN M D ASIM A MOHAMMED M D ANJU BHARDWAJ M D LINDA BARAJAS R N JUSTINE BARAJAS HAN-NA KIM M D MPH AARON L BAGGISH M D RORY B WEINER M D ANNABEL CHEN-TOURNOUX MD JANE E MARSHALL RDCS STEPHANIE A MOORE M D WILLIAM D CARLSON M D GREGORY D LEWIS M D JORDAN SHIN M D DOROTHY SULLIVAN ANP KIMBERLY PARKS D O THOMAS J WANG M D SHAWN A GREGORY M D SHANMUGAM UTHAMALINGAM M D MARC J SEMIGRAN M D | 2011 | J Am Coll Cardiol2011，58，18： | 1 |
| 7 | Uptake of chemically reactive,DNA-damaging sulfuric acid esters into renal cells by human organic anion transporters显示文摘 | Bakhiya N Stephani M Bahn A Ugele B Seidel A Burckhardt G | 2006 | J Am Soc Nephrol2006，17，5： | 1 |
| 8 | Turonian o ceanic red beds in the Eastern Alps: Concepts for palaeocean- ographic changes in the Mediterranean Tethys显示文摘 | Stephanie N M Wagreich M Wendler I | 2007 | Palaeo geography Palaeoclimatology Palaeoecology2007，251，2： | 1 |
| 9 | Comparative evaluation of radiochemotherapy with temozolomide versus stan- dard - of- care postoperative radiation alone in patients with WHO grade Ⅲ astrocytie tumors 显示文摘 | Stephanie E Combs M N Lutz E | 2008 | Radiother Oncol2008，88，2： | 1 |
| 10 | Inhibition of vascularization in rabbit corneals by heparin, cortisone pellets显示文摘 | Linbisa N Jadith F Stephanie T | 1986 | Invest Ophthalmol Vis Sci1986，27，4： | 1 |
| 11 | Providing social support may be more beneficial than receiving it: Results from a prospective study of mortality显示文摘 | Stephanie L B Randolph M N Amiram D V Dylan M S | 2003 | Psychology Science2003，，4： | 1 |
| 12 | Expression of aldehyde dehydrogenase 1 as a marker of mammary stem cells in benign and malignant breast lesions of Ghanaian women显示文摘 | Theresa Schwartz Azadeh Stark Judy Pang Baffour Awuah Celina G. Kleer Solomon Quayson Stephanie Kingman Francis Aitpillah Francis Abantanga Evelyn Jiagge Joseph K. Oppong Ernest Osei‐Bonsu Iman Martin Xiaowei Yan Kathy Toy Ernest Adjei Max Wicha Lisa A. N | 2012 | Cancer2012，，3： | 1 |
| 13 | Configuration re- search in strategic management: Key issues and suggest-ions显示文摘 | Dess G G Stephanie N Rasheed A A | 1993 | Journal of Management1993，19，4： | 1 |
| 14 | Initiator-independent and initiator-dependent rubber biosynthesis in Ficus elastica显示文摘 | Stephanie C. Espy Jay D. Keasling Javier Castillón Katrina Cornish | 2006 | Archives of Biochemistry and Biophysics2006，，1： | 1 |
| 15 | NT-proBNP and cardiac e- vents in older diabetic patients 显示文摘 | Michael R Stephanie N Michaela R | 2011 | European Jounal of Preventive Cardiology2011，18，： | 1 |
| 16 | Diagnostic accuracy of duaL-source computed tomography in the diagnosis of coronary artery disease显示文摘 | Thorsten RCJ Konstantin N Stephanie B | 2007 | Invest Radiol2007，42，10： | 1 |
| 17 | Low-eost Proeess for tow-sulfur gaso- line 显示文摘 | Lee K Stephany R David N | 1999 | Hydroearbon Proeessing1999，78，5： | 1 |
| 18 | Clustering of insulin resistance with vaseulax dysfunction and low - grade inflammation in type 2 diabetes 显示文摘 | Andrea N Elena T Stephanie B | 2006 | Diabetes2006，55，9： | 1 |
| 19 | Experimental investigation of zero phase shift effects for Coriolis flowmeters due to pipe imperfections 显示文摘 | Stephanie E Jon J T Stefan N | 2011 | Flow Measurement and Instrumentation2011，22，1： | 1 |
| 20 | Temper- ature and photoperiod affect stress resistance traits in Drosophila melanogaster显示文摘 | STEPHANIE S B VANESSA K NEDA N M | 2014 | Physiological Entomology2014，39，3： | 1 |
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