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| 1 | Is obesity associated with gastropharyngeal reflux disease?显示文摘AIM: To examine the association between obesity and gastropharyngeal reflux disease (GPRD) as well as gastroesophageal reflux disease (GERD) METHODS: We conducted a cross-sectional study of consecutive patients undergoing ambulatory 24-h dual-probe pH monitoring from July 2003 to December 2006. The association between body mass index (BMI) and parameters about gastroesophageal or gastropharyngeal reflux was examined in univariate and multivariate analyses.RESULTS: A total of 769 patients (307 men and 462 women; mean age 50.7 years) were finally enrolled. Most variables showing gastroesophageal reflux was higher in the obese patients than the patients with normal BMI. There was no difference in all the variables showing gastropharyngeal reflux according to the BMI. After adjustment for age, sex, alcohol intake and smoking, obese patients demonstrated an about 2-fold increase in risk of GERD compared with patients with normal BMI (OR, 1.9; 95 CI, 1.3-2.9), but overweight patients did not demonstrate increased risk of GERD (OR, 1.2; 95 CI, 0.8-1.7). Both obese patients and overweight patients did not demonstrated increased risk of GPRD compared with patients with normal BMI (OR, 1.1; 95 CI, 0.8-1.7; and OR, 0.9; 95 CI, 0.6-1.3, respectively).CONCLUSION: Obesity is not associated with GPRD reflux while it is associated with GERD. | Cheol Woong Choi Gwang Ha Kim Chul Soo Song Soo Geun Wang Byung Joo Lee Hoseok I Dae Hwan Kang Geun Am Song | 2008 | World Journal of Gastroenterology2008，14，2： | 5 |
| 2 | Effects of lysophosphatidic acid on human periodontal ligament stem cells from teeth extracted from dental patients显示文摘Despite their potential applications in future regenerative medicine, periodontal ligament stem cells(PDLSCs) are difficult to obtain in large amounts from patients. Therefore, maintaining sternness while expanding the cell numbers for medical use is the key to transitioning PDLSCs from the bench to the clinic. Lysophosphatidic acid(LPA), which is present in the human body and saliva, is a signaling molecule derived from phospholipids. In this study, we examined the effects of LPA on sternness maintenance in human PDLSCs. Several spindle-shaped and fibroblast-like periodontal ligament stem-like cell lines were established from PDLSC isolation. Among these cell lines, the most morphologically appropriate cell line was characterized. The expression levels of OCT4, NANOG(a stem cell marker), and CD90(a mesenchymal stem cell marker) were high. However, CD73(a negative marker of mesenchymal stem cells) expression was not observed. Notably, immunofluorescence analysis identified the expression of STRO-1, CD146(a mesenchymal stem cell marker), and sex determining region Y-box 2 at the protein level. In addition, lipid droplets were stained by Oil red O after the induction of adipogenesis for 21 days, and mineralized nodules were stained by Alizarin Red S after the induction of osteogenesis for 14 days. Alkaline phosphate staining also demonstrated the occurrence of osteogenesis. In summary, we established a human PDLSC line, which could be applied as a cell source for tissue regeneration in dental patients. However, further studies are needed to determine the detailed effects of LPA on PDLSCs. | Byung Cheol Kim Jae-In Song Kyoung-Ha So Sang-Hwan Hyun | 2019 | The Journal of Biomedical Research2019，33，2： | 3 |
| 3 | Matched Case-Control Analysis Comparing Laparoscopic and Open Pylorus-preserving Pancreaticoduodenectomy in Patients With Periampullary Tumors显示文摘 | Ki Byung Song Song Cheol Kim Dae Wook Hwang Jae Hoon Lee Dong Joo Lee Jung Woo Lee Kwang-Min Park Young-Joo Lee | 2015 | Annals of Surgery2015，，1： | 2 |
| 4 | A randomized phase II trial of S-1-oxaliplatin versus capecitabine–oxaliplatin in advanced gastric cancer显示文摘 | Gun Min Kim Hei-Cheul Jeung Sun Young Rha Hyo Song Kim Inkyung Jung Byung Ho Nam Kyung Hee Lee Hyun Cheol Chung | 2011 | European Journal of Cancer2011，，4： | 2 |
| 5 | Preoperative serum carbohydrate antigen 19-9 levels predict early recurrence after the resection of early-stage pancreatic ductal adenocarcinoma显示文摘BACKGROUND Pancreatic ductal adenocarcinoma(PDAC)is a serious disease with a poor prognosis.Only a minority of patients undergo surgery due to the advanced stage of the disease,and patients with early-stage disease,who are expected to have a better prognosis,often experience recurrence.Thus,it is important to identify the risk factors for early recurrence and to develop an adequate treatment plan.AIM To evaluate the predictive factors associated with the early recurrence of earlystage PDAC.METHODS This study enrolled 407 patients with stage I PDAC undergoing upfront surgical resection between January 2000 and April 2016.Early recurrence was defined as a diagnosis of recurrence within 6 mo of surgery.The optimal cutoff values were determined by receiver operating characteristic(ROC)analyses.Univariate and multivariate analyses were performed to identify the risk factors for early recurrence.RESULTS Of the 407 patients,98 patients(24.1%)experienced early disease recurrence:26(26.5%)local and 72(73.5%)distant sites.In total,253(62.2%)patients received adjuvant chemotherapy.On ROC curve analysis,the optimal cutoff values for early recurrence were 70 U/mL and 2.85 cm for carbohydrate antigen 19-9(CA 19-9)levels and tumor size,respectively.Of the 181 patients with CA 19-9 level>70 U/mL,59(32.6%)had early recurrence,compared to 39(17.4%)of 226 patients with CA 19-9 level≤70 U/mL(P<0.001).Multivariate analysis revealed that CA 19-9 level>70 U/mL(P=0.006),tumor size>2.85 cm(P=0.004),poor differentiation(P=0.008),and non-adjuvant chemotherapy(P=0.025)were significant risk factors for early recurrence in early-stage PDAC.CONCLUSION Elevated CA 19-9 level(cutoff value>70 U/mL)can be a reliable predictive factor for early recurrence in early-stage PDAC.As adjuvant chemotherapy can prevent early recurrence,it should be recommended for patients susceptible to early recurrence. | Sarang Hong Ki Byung Song Dae Wook Hwang Jae Hoon Lee Woohyung Lee Eunsung Jun Jaewoo Kwon Yejong Park Seo Young Park Naru Kim Dakyum Shin Hyeyeon Kim Minkyu Sung Yunbeom Ryu Song Cheol Kim | 2021 | World Journal of Gastrointestinal Surgery2021，13，11： | 2 |
| 6 | Motion-compensated Temporal Filtering for Denoise in Video Encoder显示文摘 | Song Byung Cheol Chun Kang Wook | 2004 | Electronics Letters2004，40，13： | 1 |
| 7 | Transforming Growth Factor-1 as a Useful Serologic Marker of Small Hepatocellular Carcinoma 显示文摘 | Byung Cheol Song Young-Hwa Chung Jung A Kim | 2002 | Cancer2002，94，1： | 1 |
| 8 | A comparative study of laparoscopic versus open distal pancreatectomy for left-sided ductal adenocarcinoma : A propensity score-matched analysis显示文摘 | Sang Hyun Shin Song Cheol Kim Ki Byung Song Dae Wook Hwang Jae Hoon Lee Dongjoo Lee Jung Woo Lee Eunsung Jun Kwang-Min Park Young-Joo Lee | 2014 | Journal of the American College of Surgeons2014，，： | 1 |
| 9 | Enucleation for benign or low-grade malignant lesions of the pancreas: single center experience with 65 consecutive patients显示文摘 | Ki Byung Song Song Cheol Kim Dae Wook Hwang Jae Hoon Lee Dong Joo Lee Jung Woo Lee Eun Sung Jun Sang Hyun Sin Heung En Kim Kwang-Min Park Young-Joo Lee | 2014 | Surgery2014，，： | 1 |
| 10 | A randomized phase II trial of S-1-oxaliplatin versus capecitabine–oxaliplatin in advanced gastric cancer显示文摘 | Gun Min Kim Hei-Cheul Jeung Sun Young Rha Hyo Song Kim Inkyung Jung Byung Ho Nam Kyung Hee Lee Hyun Cheol Chung | 2011 | European Journal of Cancer2011，，4： | 1 |
| 11 | A fast search algorithm for vector quantization using L2-Norm Pyramid of Codewords显示文摘 | Byung Cheol Song Jong Beom Ra | 2002 | IEEE Transactions on image processing2002，11，1： | 1 |
| 12 | A virtual frame rate control algorithm for efficient MPEG-2 video encoding显示文摘 | Song Byung Cheol Chun Kang Wook | 2003 | IEEE Transactions on Consumer Electronics2003，，： | 1 |
| 13 | A randomized phase II trial of S-1-oxaliplatin versus capecitabine–oxaliplatin in advanced gastric cancer显示文摘 | Gun Min Kim Hei-Cheul Jeung Sun Young Rha Hyo Song Kim Inkyung Jung Byung Ho Nam Kyung Hee Lee Hyun Cheol Chung | 2011 | European Journal of Cancer2011，，4： | 1 |
| 14 | Effect of Balloon-Occluded Retrograde Transvenous Obliteration on the Natural History of Coexisting Esophageal Varices显示文摘 | Yong Sung Choi Joon Hyoek Lee Dong Hyun Sinn Young Bong Song Geum-Youn Gwak Moon Seok Choi Kwang Cheol Koh Seung Woon Paik Byung Chul Yoo | 2008 | Journal of Clinical Gastroenterology2008，，9： | 1 |
| 15 | Mirizzi syndrome in an anomalous cystic duct:A case report显示文摘Mirizzi syndrome is a rare complication of gallstone disease,and results in partial obstruction of the common bile duct or a cholecystobiliary fistula. Moreover,congenital anatomical variants of the cystic duct are common,occurring in 18%-23% of cases,but Mirizzi syndrome underlying an anomalous cystic duct is an important clinical consideration. Here,we present an unusual case of typeⅠMirizzi syndrome with an uncommon anomalous cystic duct,namely,a low lateral insertion of the cystic duct with a common sheath of cystic duct and common bile duct. | Cheol Woong Jung Byung Wook Min Tae Jin Song Gil Soo Son Hong Sik Lee Seung Joo Kim Jun Won Um | 2007 | World Journal of Gastroenterology2007，13，41： | 1 |
| 16 | Motion-compensated temporal prefiltering for noise reduction in a video encoder显示文摘 | Byung Cheol Song Kong Wook Chun | 2004 | Image Processing IEEE2004，10，2： | 1 |
| 17 | Robotic versus laparoscopic distal pancreatectomy for pancreatic ductal adenocarcinoma: A propensity score-matched analysis显示文摘Background: Minimally invasive surgery is becoming increasingly popular in the field of pancreatic surgery. However, there are few studies of robotic distal pancreatectomy(RDP) for pancreatic ductal adenocarcinoma(PDAC). This study aimed to investigate the efficacy and feasibility of RDP for PDAC. Methods: Patients who underwent RDP or laparoscopic distal pancreatectomy(LDP) for PDAC between January 2015 and September 2020 were reviewed. Propensity score matching analyses were performed. Results: Of the 335 patients included in the study, 24 underwent RDP and 311 underwent LDP. A total of 21 RDP patients were matched 1:1 with LDP patients. RDP was associated with longer operative time(209.7 vs. 163.2 min;P = 0.003), lower open conversion rate(0% vs. 4.8%;P < 0.001), higher cost(15 722 vs. 12 699 dollars;P = 0.003), and a higher rate of achievement of an R0 resection margin(90.5% vs. 61.9%;P = 0.042). However, postoperative pancreatic fistula grade B or C showed no significant intergroup difference(9.5% vs. 9.5%). The median disease-free survival(34.5 vs. 17.3 months;P = 0.588) and overall survival(37.7 vs. 21.9 months;P = 0.171) were comparable between the groups. Conclusions: RDP is associated with longer operative time, a higher cost of surgery, and a higher likelihood of achieving R0 margins than LDP. | Dakyum Shin Jaewoo Kwon Jae Hoon Lee Seo Young Park Yejong Park Woohyung Lee Ki Byung Song Dae Wook Hwang Song Cheol Kim | 2023 | Hepatobiliary & Pancreatic Diseases International2023，22，2： | 0 |
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