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| 1 | Biochemical markers for non-invasive assessment of disease stage in patients with primary biliary cirrhosis显示文摘AIM: To evaluate different biochemical markers and their ratios in the assessment of primary biliary cirrhosis (PBC) stages. METHODS: This study included 112 patients with PBC who underwent a complete clinical investigation. We analyzed the correlation (Spearman's test) between ten biochemical markers and their ratios with different stages of PBC. The discriminative values were compared using areas under receiver operating characteristic (ROC) curves. RESULTS: The mean age of patients included in the study was 53.88 ± 10.59 years, including 104 females and 8 males. We found a statistically significant correlation between PBC stage and Aspartate aminotransferase (AST), Alanine aminotransferase (ALT) to platelet ratio (APRI), ALT/platelet count, AST/ALT, ALT/AST and ALT/Cholesterol ratios, with the values of Spearman's rho of 0.338, 0.476, 0.404, 0.356, 0.351 and 0.325, respectively. The best sensitivity and specificity was shown for AST/ALT, with an area under ROC of 0.660. CONCLUSION: Biochemical markers and their ratios do correlate with different sensitivity to and specificity of PBC disease stage. The use of biochemical markers and their ratios in clinical evaluation of PBC patients may reduce, but not eliminate, the need for liver biopsy. | Tamara Alempijevic Miodrag Krstic Rada Jesic Ivan Jovanovic Aleksandra Sokic Milutinovic Nada Kovacevic Slobodan Krstic Dragan Popovic | 2009 | World Journal of Gastroenterology2009，15，5： | 4 |
| 2 | Sleep structure in epileptic patients with and without antiepileptic therapy显示文摘 | Jankovic SM Levic ZM Sokic DV | 1995 | Electroencephalogr Clin Neurophysio1995，97，： | 1 |
| 3 | Seizures in multiple sclerosis显示文摘 | Sokic D Stojsavlevic N Drulovic J | 2001 | Eilesia2001，42，1： | 1 |
| 4 | Kinetics of chalcopyrite leaching by sodium nitrate in sulphurie acid 显示文摘 | SOKIC M D MARKOVIC B ZIVKOVIC D | 2009 | Hydrometallurgy2009，95，34： | 1 |
| 5 | Phenomenology and psychiatric origins of psychogenic non-epileptic seizures显示文摘 | Ristic AJ Petrovic I Vojvodic N Jankovic S Sokic D | 2004 | Srp Arh Celok Lek2004，132，12： | 1 |
| 6 | Seizures in multiple sclerosis 显示文摘 | Stojsavljevic N Drulovic J | 2001 | Epilepsia2001，42，： | 1 |
| 7 | Seizures in multiple sclerosis显示文摘 | Sokic D Stojsavlevic N Drulovic J | 2001 | Eilesia2001，42，1： | 1 |
| 8 | Sleep structure in epileptic patients with and without autiepileptic therapy显示文摘 | Jankovic SM Levic ZM Sokic DV | 1995 | Elec- troencephalog Clin Neurophysiol1995，97，： | 1 |
| 9 | Role ofHelicobacter pylori infection in gastroduodenal damage in patients start-ing NSAID therapy : 4 Months follow - up study 显示文摘 | Sokic _ Milutinovic A Kretic M Rozer - Smolovic B | 2010 | Dig Dis Sci2010，55，10： | 1 |
| 10 | Endoskopischer Ultraschall für die Differenzialdiagnose von L?sionen des Zw?lffingerdarms显示文摘 | A. Pavlovic Markovic T. R?sch T. Alempijevic M. Krstic D. Tomic P. Dugalic A. Sokic Milutinovic M. Bulajic | 2012 | Ultraschall in Med2012，，07： | 1 |
| 11 | Sleep and the epilepsies 显示文摘 | Sokic D | 2007 | Glas Srp Akad Nauka2007，49，： | 1 |
| 12 | Multiple rhythmic movement disorders in a teenage boy with excellent response to clonazepam显示文摘 | Jankovic SM Sokic DV Vojvodic NM | 2008 | Mov Disord2008，23，5： | 1 |
| 13 | Kinetics of chal- copyrite leaching by sodium nitrate in sulphuric acid 显示文摘 | Sokic M D Markovic B Zivkovic D | 2009 | Hydrometallurgy2009，95，3： | 1 |
| 14 | Sleep structure in epileptic patients with and without antiepileptic therapy显示文摘 | Jankovic SM Levic ZM Sokic DV | 1995 | Electroencephalogra Cli Neurophysio1995，97，： | 1 |
| 15 | Risk factors for laryngeal cancer显示文摘 | Sokic SI Adanja BJ Marinkovic JP | | 0，，： | 1 |
| 16 | Thermogravimetrieally and differential scanning ealorimetrieally derived kinetics of oil shale pyrolysis显示文摘 | SKALA D KOPSCH H SOKIC M NEUMANN H J JOVANOVIC J A | 1987 | Fuel1987，66，9： | 1 |
| 17 | Oil shale pyrolysis: A new approach to the kinetic investigation of different kerogen type samples显示文摘 | SKALA D SOKIC M KOPSCH H | 1988 | Thermochim Acta1988，134，： | 1 |
| 18 | Single photon emission computed tomography (SPECT) in presurgical evaluation of temporal lobe epilepsy显示文摘 | Brajkovic L Sokic D Vojvodi N | 2010 | Clin Neurophysiol2010，121，： | 1 |
| 19 | Kinetics of chalcopyrite leaching by sodium nitrate in sulphuric acid 显示文摘 | SOKIC M D MARKOVIC B ZIVKOVIC D | 2009 | Hydrometallurgy2009，95，： | 1 |
| 20 | Sleep structure in epileptic patients with and without antiepileptic therapy显示文摘 | Jankovic SM Levic ZM Sokic DV | 1995 | Electroencephalogr Clin Neurophysiol1995，97，： | 1 |
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