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3600篇 您的检索式:作者名="Smith P J"
    题名 作者 年代 出处 被引量
1Report of an international workshop to standardize baseline evaluation and response criteria for primary CNS lymphoma.显示文摘Abrey LE Batchelor TT Ferreri A J Gospodarowicz M Pulczynski EJ Zucca E Smith JR Korfel A Soussain C DeAngelis LM Neuwelt EA O′Neill BP Thiel E Shenkier T Graus F van den Bent M Seymour JF Poortmans P Armitage JO Cavalli F 2005中国神经肿瘤杂志2005,3,3:53
2在血压控制不良的高血压患者中使用数字化干预的家庭和在线血压管理:随机对照试验显示文摘HOME BP试验(The home and online management and evaluation of blood pressure)的目的是评估在初级预防中结合自我监测和自我管理的数字化干预在高血压管理中的作用。研究者纳入英国76个治疗中心经过治疗但血压控制不好(>140/90 mm Hg, 1 mm Hg=0.133 kPa)并能上网的患者622例,进行自动确定主要终点的公开随机对照试验。McMa-nus RJ Little P Stuart B Morton K Raftery J Kelly J Bradbury K Zhang J Zhu S Murray E May CR Mair FS Michie S Smith P Band R Ogburn E AllenJ Rice C Nut-tall J Williams B Yardley L 陈嘉睿(译) 叶鹏(审校) 2021中华高血压杂志2021,29,5:15
3Encapsulating peritoneal sclerosis显示文摘Encapsulating peritoneal sclerosis(EPS) is a debilitating condition characterized by a fibrocollagenous membrane encasing the small intestine, resulting in recurrent small bowel obstructions. EPS is most commonly associated with long-term peritoneal dialysis, though medications, peritoneal infection, and systemic inflammatory disorders have been implicated. Many cases remain idiopathic. Diagnosis is often delayed given the rarity of the disorder combined with non-specific symptoms and laboratory findings. Although cross-sectional imaging with computed tomography of the abdomen can be suggestive of the disorder, many patients undergo exploratory laparotomy for diagnosis. Mortality approaches 50% one year after diagnosis. Treatment for EPS involves treating the underlying condition or eliminating possible inciting agents(i.e. peritoneal dialysis, medications, infections) and nutritional support, frequently with total parenteral nutrition. EPSspecific treatment depends on the disease stage. In the inflammatory stage, corticosteroids are the treatment of choice, while in the fibrotic stage, tamoxifen may be beneficial. In practice, distinguishing between stages may be difficult and both may be used. Surgical intervention, consisting of peritonectomy and enterolysis, is timeconsuming and high-risk and is reserved for situations in which conservative medical therapy fails in institutions with surgical expertise in this area. Herein we review the available literature of the etiology, pathogenesis, diagnosis, and treatment of this rare, but potentially devastating disease.Christopher J Danford Steven C Lin Martin P Smith Jacqueline L Wolf 2018World Journal of Gastroenterology2018,24,28:13
4miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus显示文摘AIM: To investigate miR-200 family expression in Barrett's epithelium, gastric and duodenal epithelia, and esophageal adenocarcinoma. METHODS: Real-time reverse transcriptase-polymerase chain reaction was used to measure miR-200, ZEB1 and ZEB2 expression. Ingenuity Pathway Analysis of miR-200 targets was used to predict biological outcomes. RESULTS: Barrett's epithelium expressed lower levels of miR-141 and miR-200c than did gastric and duodenal epithelia (P < 0.001). In silico analysis indicated roles for the miR-200 family in molecular pathways that distinguish Barrett's epithelium from gastric and duodenalepithelia, and which control apoptosis and proliferation. All miR-200 members were downregulated in adenocarcinoma (P < 0.02), and miR-200c expression was also downregulated in non-invasive epithelium adjacent to adenocarcinoma (P < 0.02). The expression of all miR-200 members was lower in Barrett's epithelium derived high-grade dysplastic cell lines than in a cell line derived from benign Barrett's epithelium. We observed signif icant inverse correlations between miR-200 family expression and ZEB1 and ZEB2 expression in Barrett's epithelium and esophageal adenocarcinoma (P < 0.05). CONCLUSION: miR-200 expression might contribute to the anti-apoptotic and proliferative phenotype of Barrett's epithelium and regulate key neoplastic processes in this epithelium.Cameron M Smith David I Watson Mary P Leong George C Mayne Michael Z Michael Bas PL Wijnhoven Damian J Hussey 2011World Journal of Gastroenterology2011,17,8:13
5高龄对男性生育力的影响显示文摘在过去的几十年里,现代社会的压力和期望使得育龄夫妇生育年龄总体推迟。已知女性在临近40岁时卵母细胞的产生将会明显减少,而高龄对男性精子生成能力的影响还知之甚少。男性生育年龄无明确限制,因而高龄对男性生育能力的影响还不完全清楚。本文将就目前已知的高龄对男性精子质量、生育能力和子代健康的影响进行综述,希望能在医生就男性推迟生育及高龄相关的风险咨询时起到一定的指导作用。Jason R Kovac Josephine Addai Ryan P Smith Robert M Coward Dolores J Lamb Larry I Lipshultz 2013Asian Journal of Andrology2013,15,6:12
6如何设计高质量针刺临床研究:基于证据的专家共识显示文摘本针刺随机对照试验(Randomised controlled trials, RCT)专家共识是基于目前针刺试验面临的最普遍、最关键问题,由临床医生、研究人员、从事针灸和外科的临床试验专家、统计专家、临床流行病学和方法学专家以及患者组成的国际临床研究小组联合制订。该共识将有助于临床试验资助者、注册者以及期刊编辑等评估针刺RCT方案及研究结果的相关性、重要性和质量。张誉清 焦睿珉 Claudia M Witt 劳力行 刘建平 Lehana Thabane Karen J Sherman Mike Cummings Dawn P Richards Eun-Kyung Anna Kim Tae-Hun Kim Myeong Soo Lee Michael E Wechsler Benno Brinkhaus Jun J Mao Caroline A Smith 岗卫娟 刘保延 刘志顺 刘岩 郑晖 吴佳霓 AloBSO Carrasco-Labra Mohit Bhandari Philip J Devereaux 景向红 Gordon Guyatt 2022英国医学杂志中文版2022,25,6:7
7Men with a complete absence of normal sperm morphology exhibit high rates of success without assisted reproduction显示文摘在里面结合不孕, 0% 正常形式(NF ) 的反常严格的形态学是一个标准很快继续到在 vitro 授精(IVF ) 。自从没有数据,当前存在,我们与 0% NF 为人调查了结果没有帮助繁殖技术(艺术) 的使用,决定繁殖成功。有 0% NF 的 24 个人的一个队被识别(2010-2013 ) 随机与 ≥ 与 27 选择了人;是的 4% NF 控制。耐心的图表与联系并且管理同意的一块机构的评论板(IRB ) 的人一起被考察查明结果的电话问询表。在 2.5 年的一中部的后续时间以后,有 0% NF 的 29.2% 人没为他们的第一怀孕要求艺术(控制 =55.6% , P ≤0.05 ) 。当所有怀孕一起被分析时,有 0% NF 的人完成了 75% 没要求 IVF 的二十怀孕(控制 = 三十怀孕;76.7% 没要求 IVF ) 。人和女搭挡的平均年龄在有 0% NF 和 ≥ 的人之间是类似的; 4% NF。所有人有正常刺激滤泡的荷尔蒙(FSH ) ,睾丸激素,催乳激素,性别荷尔蒙绑定血球素(SHBG ) ,和 estradiol。尽管,当第一怀孕是一个自然概念(NC ) 时,全球精液参数在有 0% NF 的人是更坏的,有 0% NF (n = 7/7 ) 的人的 100% 并且 37.5% 控制(n = 3/8 ) 继续了经由 NC 有随后的怀孕。没有 IVF,有 0% NF 的人与 55.6% 控制相比在 29.2% 盒子中怀孕了。严格的形态学不应该被用来预言授精,怀孕,或实时出生潜力。在有 0% NF 的人,其他的形式应该被认为 IVF 以前立即。Jason R Kovac Ryan P Smith Miguel Cajipe Dolores J Lamb Larry I Lipshultz 2017Asian Journal of Andrology2017,19,1:7
8麻风无痛性神经炎——康复试点报告显示文摘对八个康复试点的3571例病人定期进行神经功能检查,发现无痛性神经炎151例(4.2%),共累及330条神经,包括面神经15条,尺神经98条,正中神经36条,胫后神经148条及腓总神经33条。经强的松标准方案治疗,神经功能好转235条(71.2%),其中恢复优、良者196条(59.4%),表明强的松治疗麻风无痛性神经炎既简单又行之有效,可作为常规,以减少神经不可逆性损害。讨论了无痛性神经炎与MDT的关系及其感觉与运动功能的恢复。蒋娟 张国成 韦晓宇 严良斌 李文忠 郑逖生 Jakeman P Watson J Smith C Goh Siam Kiang 1996中国麻风杂志1996,12,3:5
9Gamma irradiation of HIV-1显示文摘Richard A Smith Jesse Ingels John J Lochemes Joseph P Dutkowsky Linda L Pifer 2001Journal of Orthopaedic Research2001,,5:2
10Pentraxin binding to isolated rat liver nuclei显示文摘Shephard E G Smith P J Coetzee S 1991Biochem J1991,279,1:2
11Adrenomedullin,a multifunctional regulatory peptide 显示文摘HINSON J P KAPAS S SMITH D M 2000Endocrine Reviews2000,21,2:2
12遗传性肥胖与心房颤动的关系显示文摘观察性研究已经确定了体质量指数(body mass index,BMI)与心房颤动之间的关联。然而,从观察性研究中推断因果关系会受到混杂因素、逆因果关系和偏倚的影响。该研究的主要目的是应用BMI的遗传学预测因子评估BMI与心房颤动之间的因果关系。方法:纳入1987-2002年期间在美国、冰岛和荷兰实施的7个前瞻性人群队列研究中基线无心房颤动的欧洲血统个体51 646人,刘莉 叶鹏 Chatterjee NA Giulianini F Geelhoed B Lunetta KL Misialek JR Niemeijer MN Rienstra M Rose LM Smith AV Arking DE Ellinor PT Heeringa J Lin H Lubitz SA Soliman EZ Verweij N Alonso A Benjamin EJ Gudnason V Stricker BH van der Harst P Chasman DI Albert CM 2017中华高血压杂志2017,25,2:2
13Effects of ten Quatrnary ammonium cations on tetrachloromethane sorption to clay from water显示文摘Smith J A Jaffe P R Chiou C T 1990Environmental Science Technology1990,24,:2
14中低收入国家的慢性病:背景、决定因素与卫生政策显示文摘近年来,中低收入国家慢性病不断上升的趋势及其产生的影响受到广泛关注,但有关这种上升趋势的解释和说明大多基于高收入国家的慢性病发展史,但其所经历的发展历程与中低收入国家并不完全相同。本文对这些差异进行评价,以更好地理解中低收入国家慢性病的流行趋势,并对慢性病决定因素的相关理论加以讨论,为慢性病的防控提供循证支持。此外,本文将慢性病防控政策看作是降低人口患病风险和个体易感性的重要干预手段,并讨论了中低收入国家需要开展的相关政策研究。在此基础上进一步强调了加强初级卫生保健改革的必要性,并将其作为降低慢性病流行趋势的一项重要政策。Miranda J J Kinra S Casas J P Davey Smith G Ebrahim S 2013中国卫生政策研究2013,6,10:2
15西双版纳傣族及上海汉族群体HLA-DR2相关的DR/DQ单倍型分析显示文摘对44名西双版纳傣族和9名上海地区汉族DK2阳性个体进行了与其相关的DR/DQ单倍型组合的分析。傣族群体中DRBI-DR2亚型分布以*1602与*1502为最常见,其等位基因频率分别为43.6%与,40.0%和汉族群体中以*1501为主明显不同。傣族群体中共检出10种与DR2相关联的DR/DQ单倍型;最常见的是DRB1*1602、DRB5*0101、DQA1*0102、DQB1*0502(34.5%)与汉族及其他群体明显不同,本研究表明傣族不仅具有高频率的DR2,而且与DR2相关联的DRB1、DRB5、DQA1、DQB1单倍型组合有其独特性。范丽安 杨珏琴 姚芳娟 董建中 许玲娣 陈仁彪 M Sirkong R Vongrathna P Longta S Lekmak D Chandanayingyong A Smith J Hansen 1995中华医学遗传学杂志1995,12,3:2
16Effect of donor–recipient HLA matching at HLA A, B, C, and DRB1 on outcomes after umbilical-cord blood transplantation for leukaemia and myelodysplastic syndrome: a retrospective analysis显示文摘Mary Eapen John P Klein Guillermo F Sanz Stephen Spellman Annalisa Ruggeri Claudio Anasetti Maria Brown Richard E Champlin Joan Garcia-Lopez Gareth Hattersely Gesine Koegler Mary J Laughlin Gerard Michel Samir K Nabhan Franklin O Smith Mary M Horowitz Eli 2011Lancet Oncology2011,,13:2
17On the application of a model of condition-based maintenance 显示文摘W Wang P A Scarf M A J Smith 2000Journal of the Operational Research Society (S0160-5682)2000,,51:1
18Novel 1xN and NxN Integrated Optical Switches Using Self-lmaging Multimode GaAs/Al-GaAs Waveguides显示文摘Jenkins R M Heaton J M Wright D R Parker J T Birbeck J C H Smith G W Hilton K P 1994Appl Phys Lett 71994,64,:1
19Vascular endothelial growth factor(VEGF) expression during arterial repair in the pig显示文摘Wysocki S J Zheng M H Smith A Norman P E 1998Eur J Vasc Endovasc Surg1998,15,3:1
20The fibronectin binding proteins of Staphylococcus aureus are required for adhesion to and invasion of bovine mammary gland cells显示文摘 Nuijter P J Smith H E 1999FEMS Microbiology Lettres1999,180,1:1
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