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| 1 | Influences of atmospheric turbulence effects on the orbital angular momentum spectra of vortex beams显示文摘We investigate the atmospheric turbulence effects on orbital angular momentum(OAM) spectra of different kinds of vortex beams, including Laguerre–Gaussian(LG) beams and Bessel beams, numerically. We generate the holograms of atmospheric turbulence with different structure constants of the refractive index. The OAM spectra of distorted single-mode or multiplexed LG beams and Bessel beams are analyzed. Compared with the OAM spectra of the two kinds of vortex beams, the spectrum of the Bessel beams is more dispersive. The results illustrate that Bessel beams suffer more from turbulent atmosphere than LG beams. | Shiyao Fu Chunqing Gao | 2016 | Photonics Research2016,4,5: | 17 |
| 2 | Ship collision impact on the structural load of an offshore wind turbine显示文摘When a maintenance and operations ship is berthing,there is a chance the ship may collide into the wind turbine.When these ships collide into wind turbine structures,this can result in significant changes to the foundation and structure of the wind turbine.In this paper,the structural load of a 4 MW offshore wind turbine was analyzed during a collision with an operations and maintenance ship.The variations in the wind speeds on hub height,waves,and the sea currents were measured.The dynamic simulation of the wind turbine was carried out using the test data as the input parameters.As a result,the load condition of the turbine without a collision was obtained.Finally,the measured turbine load was compared with the simulation results.This study shows that the collision of the operation and the maintenance ship increases the bending moments at the tower’s bottom and the blade’s roots. | Haikun Jia Shiyao Qin Ruiming Wang Yang Xue Deyi Fu Anqing Wang | 2020 | Global Energy Interconnection2020,3,1: | 4 |
| 3 | Macrophage membrane-coated nanocarriers Co-Modified by RVG29 and TPP improve brain neuronal mitochondria-targeting and therapeutic efficacy in Alzheimer's disease mice显示文摘Neuronal mitochondrial dysfunction caused by excessive reactive oxygen species(ROS)is an early event of sporadic Alzheimer's disease(AD),and considered to be a key pathologic factor in the progression of AD.The targeted delivery of the antioxidants to mitochondria of injured neurons in brain is a promising therapeutic strategy for AD.A safe and effective drug delivery system(DDS)which is able to cross the blood-brain barrier(BBB)and target neuronal mitochondria is necessary.Recently,bioactive materials-based DDS has been widely investigated for the treatment of AD.Herein,we developed macrophage(MA)membrane-coated solid lipid nanoparticles(SLNs)by attaching rabies virus glycoprotein(RVG29)and triphenylphosphine cation(TPP)molecules to the surface of MA membrane(RVG/TPP-MASLNs)for functional antioxidant delivery to neuronal mitochondria.According to the results,MA membranes camouflaged the SLNs from being eliminated by RESrich organs by inheriting the immunological characteristics of macrophages.The unique properties of the DDS after decoration with RVG29 on the surface was demonstrated by the ability to cross the BBB and the selective targeting to neurons.After entering the neurons in CNS,TPP further lead the DDS to mitochondria driven by electric charge.The Genistein(GS)-encapsulated DDS(RVG/TPP-MASLNs-GS)exhibited the most favorable effects on reliveing AD symptoms in vitro and in vivo by the synergies gained from the combination of MA membranes,RVG29 and TPP.These results demonstrated a promising therapeutic candidate for delaying the progression of AD via neuronal mitochondria-targeted delivery by the designed biomimetic nanosystems. | Yang Han Chunhong Gao Hao Wang Jiejie Sun Meng Liang Ye Feng Qianqian Liu Shiyao Fu Lin Cui Chunsheng Gao Yi Li Yang Yang Baoshan Sun | 2021 | Bioactive Materials2021,6,2: | 4 |
| 4 | Non-probe compensation of optical vortices carrying orbital angular momentum显示文摘In this paper, we demonstrate a scheme for compensating distorted optical vortex beams carrying orbital angular momentum. By inputting the intensity profile into the Gerchberg–Saxton algorithm [Optik 35, 237(1972)], the pre-compensation phase mask can be acquired. No additional probe beams are introduced, and all the computing is aiming at the transmitted vortex beams. The distorted vortex beams are investigated experimentally before and after pre-compensation, showing favorable compensation performance. This scheme will find applications in the areas of rotation detection, optical communications, and so on. | SHIYAO FU TONGLU WANG SHIKUN ZHANG ZHEYUAN ZHANG YANWANG ZHAI CHUNQING GAO | 2017 | Photonics Research2017,5,3: | 3 |
| 5 | New automatic tool for finding impossible differentials and zero-correlation linear approximations显示文摘Dear editor,Impossible differential cryptanalysis and zero-correlation linear cryptanalysis are two powerful methods in the block cipher field.Herein,we present an automatic tool to find impossible differentials(IDs)and zero-correlation linear approximations(ZCLAs)for both ARX and S-box-based ciphers.Similar to the idea of using mixed-integer linear programming(MILP)models for differential cryptanalysis in[1],we first use linear inequalities to describe all the target cipher's components exactly. | Tingting CUI Shiyao CHEN Kai FU Meiqin WANG Keting JIA | 2021 | Science China(Information Sciences)2021,64,2: | 3 |
| 6 | Photosensitive pro-drug nanoassemblies harboring a chemotherapeutic dormancy function potentiates cancer immunotherapy显示文摘Immunotherapy combined with effective therapeutics such as chemotherapy and photodynamic therapy have been shown to be a successful strategy to activate anti-tumor immune responses for improved anticancer treatment.However,developing multifunctional biodegradable,biocompatible,low-toxic but highly efficient,and clinically available transformed nano-immunostimulants remains a challenge and is in great demand.Herein,we report and design of a novel carrier-free photo-chemotherapeutic nano-prodrug COS-BA/Ce6 NPs by combining three multifunctional components-a self-assembled natural small molecule betulinic acid(BA),a water-soluble chitosan oligosaccharide(COS),and a low toxic photosensitizer chlorin e6(Ce6)-to augment the antitumor efficacy of the immune adjuvant anti-PD-L1-mediated cancer immunotherapy.We show that the designed nanodrugs harbored a smart and distinctive“dormancy”characteristic in chemotherapeutic effect with desired lower cytotoxicity,and multiple favorable therapeutic features including improved^(1)O_(2)generation induced by the reduced energy gap of Ce6,pH-responsiveness,good biodegradability,and biocompatibility,ensuring a highly efficient,synergistic photochemotherapy.Moreover,when combined with anti-PD-L1 therapy,both nano-coassembly based chemotherapy and chemotherapy/photodynamic therapy(PDT)could effectively activate antitumor immunity when treating primary or distant tumors,opening up potentially attractive possibilities for clinical immunotherapy. | Jianjun Cheng Haitian Zhao Bin Li Hua Zhang Qianyu Zhao Shiyao Fu Ying Han Weihong Lu Jiahua Shi Xin Yang | 2023 | Acta Pharmaceutica Sinica B2023,13,2: | 0 |
| 7 | Corrigendum to“Macrophage membrane-coated nanocarriers Co-Modified by RVG29 and TPP improve brain neuronal mitochondria-targeting and therapeutic efficacy in Alzheimer’s disease mice”[Bioactive materials 6(2021)529-542]显示文摘The authors regret publishing the incorrect address and affiliation.They have been now revised as follows:1.The Addresses are updated from.“a School of Traditional Chinese Medicine,Shenyang Pharmaceutical University,Shenyang,110016,PR China b State Key Laboratory of Toxicology and Medical Countermeasures,Beijing Institute of Pharmacology and Toxicology,Beijing,100850,PR China c School of Functional Food and Wine,Shenyang Pharmaceutical University,Shenyang,10016,PR China. | Yang Han Chunhong Gao Hao Wang Jiejie Sun Meng Liang Ye Feng Qianqian Liu Shiyao Fu Lin Cui Chunsheng Gao Yi Li Yang Yang Baoshan Sun | 2022 | Bioactive Materials2022,7,1: | 0 |
| 8 | Exploring the psychological impact of the 2022 SARS-CoV-2 Omicron variant outbreak in China显示文摘To the editor:The impact of the coronavirus disease 2019(COVID-19)pandemic in 2020 on mental health was substantialin Chinai2and various other countries.34 Beyond the direct consequences of COVID-19,the pandemic created an environment in which many determinants of mental health were affected.Issues associated with the pandemic,such as loss of livelihood,limited access to medical services,reduced social interactions,and economic downturn,could potentially have adverse effects on the population's mental well-being.5 In November 2021,the World Health Organization(WHO)designated the new variant of the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),variant B.1.1.529,as a variant of concern and named it Omicron;its rapid mutation and spread raised a new global health concern. | Gangbin Han Guirong Cheng Feifei Hu Chunli Li Dan Liu Juan Zhou Jing Liu Linya Huang Xiaochang Liu Qianqian Nie Dan Song Deyang Zeng Lang Xu Jinquan Li Yushan Chen Zhen Wei Qiong Wu Xiaoming He Qingming Wu Wei Tan Yufei Mei Xingxing Chen Yangming Ou Jingjing ZhangYafu Yu Mengliu Yang Pengfei Lian Fukai Zhou Renjia Fan Hong Wan Chenlu Hu Yidi Fu Shiyue Li Junyi Wang Cheng Cai Mengdie Pei Yuyang Cui Wanying Cai Yiqing Li Shiyao Pan Chang Chen Yan He Zhaoxia Wu Liu Hu Liang Tao Hongyan Xiao Xinyan Xie Yan Zeng | 2023 | General Psychiatry2023,36,6: | 0 |