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| 1 | Laparoscopic appendectomy for acute appendicitis: How to discourage surgeons using inadequate therapy显示文摘Acute appendicitis(AA) develops in a progressive and irreversible manner, even if the clinical course of AA can be temporarily modified by intentional medications. Reliable and real-time diagnosis of AA can be made based on findings of the white blood cell count and enhanced computed tomography. Emergent laparoscopic appendectomy(LA) is considered as the first therapeutic choice for AA. Interval/delayed appendectomy at 6-12 wk after disease onset is considered as unsafe with a high recurrent rate during the waiting time. However, this technique may have some advantages for avoiding unnecessary extended resection in patients with an appendiceal mass. Nonoperative management of AA may be tolerated only in children. Postoperative complications increase according to the patient's factors, and temporal avoidance of emergent general anesthesia may be beneficial for high-risk patients. The surgeon's skill and cooperation of the hospital are important for successful LA. Delaying appendectomy for less than 24 h from diagnosis is safe. Additionally, a semi-elective manner(i.e., LA within 24 h after onset of symptoms) may be paradoxically acceptable, according to the factors of the patient, physician, and institution. Prompt LA is mandatory for AA. Fortunately, the Japanese government uses a universal health insurance system, which covers LA. | tomohide hori takafumi machimoto yoshio kadokawa toshiyuki hata tatsuo ito shigeru kato daiki yasukawa yuki aisu yusuke kimura maho sasaki yuichi takamatsu taku kitano shigeo hisamori tsunehiro yoshimura | 2017 | World Journal of Gastroenterology2017，23，32： | 18 |
| 2 | Protocol for laparoscopic cholecystectomy: Is it rocket science?显示文摘Laparoscopic cholecystectomy(LC) does not require advanced techniques, and its performance has therefore rapidly spread worldwide. However, the rate of biliary injuries has not decreased. The concept of the critical view of safety(CVS) was first documented two decades ago. Unexpected injuries are principally due to misidentification of human factors. The surgeon's assumption is a major cause of misidentification, and a high level of experience alone is not sufficient for successful LC. We herein describe tips and pitfalls of LC in detail and discuss various technical considerations.Finally, based on a review of important papers and our own experience, we summarize the following mandatory protocol for safe LC:(1) consideration that a high level of experience alone is not enough;(2) recognition of the plateau involving the common hepatic duct and hepatic hilum;(3) blunt dissection until CVS exposure;(4) Calot's triangle clearance in the overhead view;(5) Calot's triangle clearance in the view from underneath;(6) dissection of the posterior right side of Calot's triangle;(7) removal of the gallbladder body; and(8) positive CVS exposure. We believe that adherence to this protocol will ensure successful and beneficial LC worldwide, even in patients with inflammatory changes and rare anatomies. | Tomohide Hori Fumitaka Oike Hiroaki Furuyama Takafumi Machimoto Yoshio Kadokawa Toshiyuki Hata Shigeru Kato Daiki Yasukawa Yuki Aisu Maho Sasaki Yusuke Kimura Yuichiro Takamatsu Masato Naito Masaya Nakauchi Takahiro Tanaka Daigo Gunji Kiyokuni Nakamura Kiyoko Sato Masahiro Mizuno Taku Iida Shintaro Yagi Shinji Uemoto Tsunehiro Yoshimura | 2016 | World Journal of Gastroenterology2016，22，47： | 3 |
| 3 | Presenilin-2 in the cynomolgus monkey brain: investigation of age-related changes显示文摘 | Nobuyuki Kimura Shin’ ichiro Nakamura Fumiko Ono Ippei Sakakibara Yoshiyuki Ishii Shigeru Kyuwa Yasuhiro Yoshikawa | 2004 | Primates2004，，3： | 1 |
| 4 | Clinical Evaluation of Schizophyllan Adjuvant Immunochemotherapy for Patients with Resectable Gastric Cancer-A Randomized Controlled Trial显示文摘 | Shigeru Fujimoto Hisashi Furue Tadashi Kimura | 1984 | Japanese Journal of Surgery1984，14，4： | 1 |
| 5 | Antiplatelet Therapy and Stent Thrombosis After Sirolimus-Eluting Stent Implantation显示文摘 | Takeshi Kimura Takeshi Morimoto Yoshihisa Nakagawa Toshihiro Tamura Kazushige Kadota Hitoshi Yasumoto Hideo Nishikawa Yoshikazu Hiasa Toshiya Muramatsu Taiichiro Meguro Naoto Inoue Hidehiko Honda Yasuhiko Hayashi Shunichi Miyazaki Shigeru Oshima Takashi H | 2009 | Circulation2009，，7： | 1 |
| 6 | Characterization of fish muscle typeicollagen显示文摘 | Shigeru kimura Xiao Ping Zhu Risako Matsui | 1988 | Food Science1988，53，5： | 1 |
| 7 | Flow cytometric examination of p53 protein in primary tumors and metastases to the liver and lymph nodes of colorectal cancer显示文摘 | Dr. Osamu Kimura M.D. Kenji Sugamura M.D. Tosihisa Kijima M.D. Masato Makino M.D. Hiroyuki Shirai M.D. Shigeru Tatebe M.D. Hisao Ito M.D. Nobuaki Kaibara M.D | 1996 | Diseases of the Colon & Rectum1996，，12： | 1 |
| 8 | Randomized phase II trial of first-line treatment with tailored irinotecan and S-1 therapy versus S-1 monotherapy for advanced or recurrent gastric carcinoma (JFMC31-0301)显示文摘 | Yoshito Komatsu Yutaka Takahashi Yutaka Kimura Hisashi Oda Yusuke Tajima Shigeyuki Tamura Jo Sakurai Takehiro Wakasugi Shigeru Tatebe Masahiro Takahashi Yuh Sakata Masaki Kitajima Junichi Sakamoto Shigetoyo Saji | 2011 | Anti-Cancer Drugs2011，，6： | 1 |
| 9 | Histiocytic sarcoma of the spleen: case report of asymptomatic onset of thrombocytopenia and complex imaging features显示文摘 | Shinichi Kobayashi Fumihiko Kimura Yukihiro Hama Kazuto Ogura Hiroki Torikai Ayako Kobayashi Takashi Ikeda Ken Sato Shinsuke Aida Shigeru Kosuda Kazuo Motoyoshi | 2008 | International Journal of Hematology2008，，1： | 1 |
| 10 | Protective effect of donepezil in primary-cultured rat cortical neurons exposed to N -methyl- d -aspartate (NMDA) toxicity显示文摘 | Shigeru Akasofu Manami Kimura Takashi Kosasa Hiroo Ogura Kohei Sawada | 2005 | European Journal of Pharmacology2005，，3： | 1 |
| 11 | Analysis of Sentinel Node Involvement in Gastric Cancer显示文摘 | Daisaku Morita Hitoshi Tsuda Takashi Ichikura Mikihiko Kimura Shinsuke Aida Shigeru Kosuda Johji Inazawa Hidetaka Mochizuki Osamu Matsubara | 2007 | Clinical Gastroenterology and Hepatology2007，，9： | 1 |
| 12 | Gastric injury caused by low-dose aspirin therapy in consecutive Japanese patients: a prospective study显示文摘 | Shoji Fukuda Shigeru Hosaka Naomi Ozawa Sam Akita Toshitaka Kashima Sosuke Kimura Junichi Akiyama Tetsuya Mizoue | 2012 | General Thoracic and Cardiovascular Surgery2012，，： | 1 |
| 13 | A Multicenter Randomized Comparison of Paclitaxel-coated Balloon Catheter with Conventional Balloon Angioplasty in Patients with Bare-metal Stent Restenosis and Drug-eluting Stent Restenosis显示文摘 | Seiji Habara Masashi Iwabuchi Naoto Inoue Shigeru Nakamura Ryuta Asano Shinsuke Nanto Yasuhiko Hayashi Nobuo Shiode Shigeru Saito Yuji Ikari Takeshi Kimura Joji Hosokawa Masato Nakamura Jun-ichi Kotani Ken Kozuma Kazuaki Mitsudo | 2013 | American Heart Journal2013，，： | 1 |
| 14 | A large-scale genetic association study of ossification of the posterior longitudinal ligament of the spine显示文摘 | Taizo Horikoshi Koichi Maeda Yoshiharu Kawaguchi Kazuhiro Chiba Kanji Mori Yu Koshizuka Shigeru Hirabayashi Kazuhito Sugimori Morio Matsumoto Hiroshi Kawaguchi Makoto Takahashi Hisashi Inoue Tomoatsu Kimura Yoshitaka Matsusue Itsuro Inoue Hisatoshi Baba K | 2006 | Human Genetics2006，，6： | 1 |
| 15 | Development of Ni catalysts for tar removal by steam gasification of biomass显示文摘 | Takeo Kimura Tomohisa Miyazawa Jin Nishikawa Shigeru Kado Kazu Okumura Toshihiro Miyao Shuichi Naito Kimio Kunimori Keiichi Tomishige | 2006 | Applied Catalysis B, Environmental2006，，： | 1 |
| 16 | Charecterization of fish muscle type I collagen显示文摘 | Xiao-Ping Zhu Risako Matsui | 1988 | Food Science1988，53，5： | 1 |
| 17 | Synthesis of 8- C -glucosylflavones显示文摘 | Toshihiro Kumazawa Takayuki Kimura Shigeru Matsuba Shingo Sato Jun-ichi Onodera | 2001 | Carbohydrate Research2001，，3： | 1 |
| 18 | Alteration of energy production by the heart in CRF patients undergoing peritoneal dialysis显示文摘 | Goichi Ogimoto Tsutomu Sakurada Keiko Imamura Shingo Kuboshima Teruhiko Maeba Kenjiro Kimura Shigeru Owada | 2003 | Molecular and Cellular Biochemistry2003，，： | 1 |
| 19 | Milk protein-derived substance, FP-10, that inhibits adhesion of Helicobacter pylori to gastric mucosa 显示文摘 | Hiramoto Shigeru Kimura Nobutake Suzuki Yoshio | 2005 | Curr Top Pept Protein Res2005，7，： | 1 |
| 20 | Nidamental Gland Mucosubstance from the Squid lllex argentinus: Salt -soluble Component as a Mucin Complex 显示文摘 | Yoko Sugiura Shigeru Kimura | 1995 | Fisheries Science1995，61，6： | 1 |
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