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| 1 | Using deep learning to detect small targets in infrared oversampling images显示文摘According to the oversampling imaging characteristics, an infrared small target detection method based on deep learning is proposed. A 7-layer deep convolutional neural network(CNN) is designed to automatically extract small target features and suppress clutters in an end-to-end manner. The input of CNN is an original oversampling image while the output is a cluttersuppressed feature map. The CNN contains only convolution and non-linear operations, and the resolution of the output feature map is the same as that of the input image. The L1-norm loss function is used, and a mass of training data is generated to train the network effectively. Results show that compared with several baseline methods, the proposed method improves the signal clutter ratio gain and background suppression factor by 3 – 4 orders of magnitude, and has more powerful target detection performance. | LIN Liangkui WANG Shaoyou TANG Zhongxing | 2018 | Journal of Systems Engineering and Electronics2018，29，5： | 14 |
| 2 | Al-doped TiO2 mesoporous materials: synthesis and photodegradation properties显示文摘 | Shaoyou Liu Guocong Liu Qingge Feng | 2010 | Journal of Porous Materials2010，，2： | 1 |
| 3 | Quantitation of doxorubicin uptake,eitlux, and modulation of multidrug resistance(MDR) in MDR human cancer cells显示文摘 | Fei Shen Shaoyou Chu I Aimee K | 2008 | The Journal of Pharmacology and Experimental Therapeutics2008，324，1： | 1 |
| 4 | Effect of Ethanol on Synthesis and Electrochemical Property of Mesoporous Al-doped Titanium Dioxide via Solid-state Reaction显示文摘Mesoporous aluminum-doped titanium dioxide(Al-TiO2) materials with high specific surface areas were prepared via a solid-state reaction route.The properties of these materials were characterized by X-ray diffraction(XRD),high resolution transmission electron microscopy(HRTEM),energy dispersive spectroscopy(EDS),N2 absorption-desorption,ultraviolet visible light spectroscopy(UV-Vis) and electrochemical spectroscopy.The results show that the mesoporous structure of the product with ethanol is composed of anatase laced crystal walls with amorphous grain boundaries formed gradually by degradation.Compared with those without ethanol,these samples possess larger crystallite size since ethanol decreases the pore size at higher temperature.With the increase of ethanol amount,however,the crystallite size will grow.The amorphous grain boundaries in the mesoporous material,with a large impedance and low incidental cyclic potential,are difficult to effectively degrade and the phase transformation temperature is changed from 500 to 550℃.The growth rate of Al-TiO2 crystallites that obeys the quadratic polynomial equation may be controlled. | LIU Shaoyou LU Jianping FENG Qingge TANG Wcnhua | 2011 | Chinese Journal of Chemical Engineering2011，19，4： | 1 |
| 5 | 显示文摘 | Liu Shaoyou Tang Qunli Feng Qingge | 2011 | Applied Surface Science2011，257，： | 1 |
| 6 | Al-doped TiO 2 mesoporous materials: synthesis and photodegradation properties显示文摘 | Shaoyou Liu Guocong Liu Qingge Feng | 2010 | Journal of Porous Materials2010，，2： | 1 |
| 7 | Synthesis of S/ Cr doped mesoporous TiO2 with high active visible light degradation property via solid state reaction route显示文摘 | Liu Shaoyou Tang Qunli Feng Qingge | 2011 | Applied Surface Science2011，257，： | 1 |
| 8 | Pegylated interferon α‐2a plus ribavirin for decompensated hepatitis C virus‐related cirrhosis: relationship between efficacy and cumulative dose显示文摘 | Yan Xu Wenqian Qi Xu Wang Ping Zhao Yonggui Zhang Qian Zhang Shaoyou Qin Jiangbin Wang | 2014 | Liver Int2014，，10： | 1 |
| 9 | Synthesis of mesoporous chro- mium aluminophosphate(CrAlPO)via solid state reaction at low temperature显示文摘 | Liu Shaoyou Chao Zisheng | 2012 | Journal of Wuhan University of Tech- nology-Mater Sci Ed2012，27，2： | 1 |
| 10 | A platform to standardize, store, and visualize proteomics experimental data显示文摘与功能的 genomics 研究的发展,大规模 proteomics 研究现在是普遍的,提出为数据存储,交换,和分析的重要挑战。这里我们在场为管理 proteomics 作为一个平台探索数据库(IPED ) 的综合 Proteomics 试验性的数据(进程和结果数据) 。IPED 基于 Proteome 试验性的数据仓库(PEDRo ) 的纲要,并且遵循人的 Proteome 组织的 Proteomics 标准委员会起草的普罗蒂米克斯将军标准(GPS ) 。在我们的工作,我们为 IPED 站台开发了三个部件:IPED 顾客编辑, IPED 服务者软件,和 IPED 网接口。顾客编辑收集试验性的数据并且产生一种可扩展的标注语言(XML ) 遵循 PEDRo 和 GPS 的数据文件;服务器软件分析 XML 数据文件和负担信息进一个核心数据库;并且网接口显示试验性的结果,提供数据的一个方便图形的代表。给定的软件便利和数据丰富, IPED 是为数据交换的一个强大的平台并且为 proteomics 社区介绍一个重要资源。在它的当前的版本, IPED 在 http://gffzzcc104d6022874f0chncxwnwn6c0bk6kk9.ffgz.tsg.suse.edu.cn/iped2 是可得到的。 | Guangyong Zheng Hong Li Chuan Wang Quanhu Sheng Haiwei Fan Shaoyou Yang Boshu Liu Jianliang Dai Rong Zeng Lu Xie | 2009 | Acta Biochimica et Biophysica Sinica2009，41，4： | 0 |
| 11 | A self-assembling prodrug nanosystem to enhance metabolic stability and anticancer activity of gemcitabine显示文摘Self-assembly is a powerful approach in molecular engineering for biomedical applications,in particu-lar for creating self-assembling prodrugs.Here,we report a self-assembling prodrug of the anticancer drug gemcitabine(Gem)based on amphiphilic dendrimer approach.The prodrug reported in this study demonstrates high drug loading(40%)and robust ability to self-assemble into small nanomicelles,which increase the metabolic stability of Gem and enable entry into cells via endocytosis,hence bypassing transport-mediated uptake.In addition,this prodrug nanosystem exhibited an effective pH-and enzyme-responsive release of Gem,resulting in enhanced anticancer activity and reduced toxicity.Harboring ad-vantageous features of both prodrug-and nanotechnology-based drug delivery,this self-assembling Gem prodrug nanosystem constitutes a promising anticancer candidate.This study also offers new perspectives of the amphiphilic dendrimer nanoplatforms for the development of self-assembling prodrugs. | Mei Cong Guangling Xu Shaoyou Yang Jing Zhang Wenzheng Zhang Dinesh Dhumal Erik Laurini Kaiyue Zhang Yi Xia Sabrina Pricl Ling Peng Weidong Zhao | 2022 | Chinese Chemical Letters2022，33，5： | 0 |
| 12 | Placental transfer of bisphenol diglycidyl ethers (BDGEs) and its association with maternal health in a population in South of China显示文摘Despite high production and usage,little is known about exposure to bisphenol diglycidyl ethers(BDGEs)and their derivatives in pregnant women and fetuses.In this study,we determined nine BDGEs in 106 paired maternal and cord serum samples collected from e-waste dismantling sites in South of China.Bisphenol A bis(2,3-dihydroxypropyl)glycidyl ether(BADGE⋅2H_(2)O),bisphenol A(3-chloro-2-hydroxypropyl)(2,3-dihydroxypropyl)glycidyl ether(BADGE⋅HCl⋅H_(2)O),and bisphenol F diglycidyl ether(BFDGE)were the major BDGEs,with median concentrations of 0.57,4.07,and 1.60 ng/mL,respectively,in maternal serum,and of 3.58,5.61,and 0.61 ng/mL,respectively,in cord serum.The transplacental transfer efficiencies(TTEs)were estimated for BDGEs found in samples,and median values were in the range of 0.98(BFDGE)to 5.91(BADGE⋅2H_(2)O).Our results suggested that passive diffusion plays a role in the placental transfer of BADGE⋅HCl⋅H_(2)O and BFDGE,whereas several mechanisms contribute to the high accumulation of BADGE⋅2H_(2)O in cord serum.Multiple linear regression analysis indicated significant associations between maternal serum concentrations of BDGEs and blood clinical biomarkers,especially those related to liver injuries,such as alanine aminotransferase(ALT),aspartate aminotransferase(AST),alkaline phosphatase(ALP),and adenosine deaminase(ADA)(P<0.05).To our knowledge,this is the first study to report the occurrence of BDGEs in paired maternal–fetal serum samples and provide new insights into prenatal and fetal exposures.The newly discovered TTEs in maternal–fetal pairs contribute to a fuller inventory of the transmission activity of pollutants in the human body,ultimately adding to a more significant comprehensive risk evaluation. | Bo Zhang Henglin Zhang Xueyuan Bai Tao Zhang Jingchuan Xue Shaoyou Lu Kurunthachalam Kannan | 2022 | Eco-Environment & Health2022，1，4： | 0 |
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