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    题名 作者 年代 出处 被引量
1Thewater loadtest:ob-servationsfrom healthy controls and patients with functional dyspepsia显示文摘Ones MP Hoffmans Shahd 2003AmJ Physiol Gastrointest Liver Physiol2003,284,6:1
2Effect of long chain alcohols on micellar relaxation time and foaming properties of sodium dodecyl sulfate solutions 显示文摘Patist A Axelberd T Shahd O 1998Journal of Colloid and Interface Science1998,208,:1
3Cognitive and psychiatric comorbidities in neuromyelitis optica显示文摘Perry Moore Abigail Methley Catherine Pollard Kerry Mutch Shahd Hamid Liene Elsone Anu Jacob 2016Journal of the Neurological Sciences2016,,:1
4双相磷酸镁钙微球体外成血管和促成骨研究显示文摘磷酸三钙(β-TCP)陶瓷替代材料由于其与骨矿物成分相近及良好的生物相容性和骨传导性,近年来被广泛关注,常以纳米颗粒、支架和微球等形式用于骨修复。本研究制备了五种不同的磷酸三钙/磷酸三镁(TMP)(TCP、25%TMP、50%TMP、75%TMP和TMP)复合微球并作了相应表征。随着复合微球中TMP含量增加,微球释放的Mg^(2+)和Ca^(2+)的累积浓度增加,且TMP可以调节复合微球的降解速率。以小鼠胚胎成骨细胞前体细胞(MC3T3-E1)和人脐静脉内皮细胞(HUVECs)为模型,评价了该复合微球的生物相容性、成血管和成骨作用。结果表明,与TCP、TMP和75%TMP相比,25%TMP和50%TMP复合微球具有更好的细胞相容性,对HUVECs有一定的促增殖作用。因此,含25%TMP和50%TMP的复合微球对血管生成和成骨具有更积极的作用。吴未 BAKHET Shahd ASANTE Naomi Addai KAREEM Shefiu KOMBO Omar Ramadhan 李宾斌 戴红莲 2023无机材料学报2023,38,7:0
5Serum leptin level in Sudanese women with unexplained infertility and its relationship with some reproductive hormones显示文摘BACKGROUND The excessive concentration of leptin has negative effects on all aspects of female reproduction.Despite this established relationship,the exact role of leptin in women’s fertility is not clear enough and needs more clarification.AIM To evaluate the serum leptin levels in Sudanese women and to ascertain the relationship between serum leptin levels and unexplained infertility(UI).METHODS A matched(age and body mass index)case-control study was conducted from March 2021 to February 2022.The study samples were 210 women with UI and 190 fertile women of reproductive age who were attending the maternity hospitals and fertility clinics in Khartoum state Sudan.The serum concentration of leptin and other serum biomarkers were determined using enzyme-linked immunosorbent assays.RESULTS The results showed that there was a highly statistically significant difference between the two groups(P<0.001)for all examined eight biomarkers.Whereby,leptin,luteinizing hormone(LH)/follicular stimulating hormone(FSH)ratio,prolactin hormone(PRL)and testosterone(T)were significantly higher in the UI group compared with the control group.In contrast,FSH and estradiol(E2)/T ratio were significantly lower in the UI group than in the control group and the effect size test for the difference between the two groups was very large(effect size>0.80),for leptin level,LH/FSH ratio,PRL level,and E2/T ratio,and large(effect size 0.50-≤0.80)for FSH and T.CONCLUSION This study reveals that leptin could be a potential biomarker for UI in Sudanese women and it may be useful for identifying women with a high risk of infertility.Abdullah Abdulslam Abdullah Musa Ahmed Adesina Oladokun Nasir Adam Ibrahim Shahd Nourain Adam 2022World Journal of Biological Chemistry2022,13,5:0
6Practical guide:Glucagon-like peptide-1 and dual glucosedependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonists in diabetes mellitus显示文摘Practical guide:Glucagon-like peptide-1 and dual glucosedependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonists in diabetes mellitus common second-line choice after metformin for treating T2DM.Various considerations can make selecting and switching between different GLP-1 RAs challenging.Our study aims to provide a comprehensive guide for the usage of GLP-1 RAs and dual GIP and GLP-1 RAs for the management of T2DM.Saleh Fahad Alqifari Omar Alkomi Abdullah Esmail Khadijeh Alkhawami Shahd Yousri Mohamad Ayham Muqresh Nawwarah Alharbi Abdullah A Khojah Ahmed Aljabri Abdulrahman Allahham Kousalya Prabahar Hanan Alshareef Mohammed Aldhaeefi Tariq Alrasheed Ali Alrabiah Laila A AlBishi 2024World Journal of Diabetes2024,15,3:0
7In Vitro Angiogenic Behavior of HUVECs on Biomimetic SF/SA Composite Scaffolds显示文摘The 60Fc and 70Fc SF/SA blend scaffolds were prepared to mimic the functions of the native ECM for skin regeneration.Human Umbilical Vein Endothelial Cells(HUVECs)were used to examine the cell cytotoxicity,adhesion,growth factors secretion and the gene expression of associated angiogenic factors.Cell proliferation,adhesion and live-dead analyses showed that HUVECs could better attach,grow,and proliferate on the 70Fc scaffolds compared with 60Fc scaffolds and unmodified controls.Furthermore,the 70Fc scaffolds showed higher levels of specific angiogenic proteins and genes expression as well.This study suggests that the involvement of higher composition of SF(about 70%)than that of SA on the blended scaffolds could be advantageous as it is more suitable to promote angiogenesis,which is potential for vascularization during skin repair.KOMBO Omar Ramadhan 王欣宇 SHEN Ying LIU Jiawei DONG Xianzhen SHAO Qi LONG Yanpiao DONG Kuo BAKHET Shahd Fateh El-Rahman Elkhider 李宾斌 2021Journal of Wuhan University of Technology(Materials Science)2021,36,3:0
8Prostate resection speed:A key factor for training and broad outcomes?显示文摘BACKGROUND Trans-urethral resection of prostate(TURP) is one of the most commonly performed operations in urology to treat bladder outflow obstruction(BOO) in men. TURP surgery is also a key for endo-urological training in the British National Health Service(NHS) for training junior urologists. The working hypothesis is that prostate resection speed(PRS) in the context of bipolar TURP surgery, is not a key factor in major complication rates or broad patient outcomes at 3 mo after surgery, and therefore supervising consultants should not focus primarily on resection speed when teaching TURP.AIM To investigate objective differences in consultants vs trainees PRS and whether PRS affected complication rates/outcomes after TURP.METHODS Retrospective descriptive study analyzing patient case-notes, operative and electronic records, study undertaken at Burton Queen's Hospital NHS Foundation Trust, United Kingdom, a secondary care centre in the public sector of the NHS. Participants included: all Bipolar TURPs undertaken between13/04/2016 and 27/06/2017. Exclusions: patients undergoing concomitant operations or where intra-operative equipment problems occurred. Resected prostate(g), operative time, post-operative complications and outcomes at 3-mo were obtained from electronic records. Clavien-Dindo Grade II complications or above considered significant. Binary successful yes/no outcome at 3-mo after surgery included both patients who reported moderate to significant symptom improvement, or being catheter-free for those catheterized before TURP.RESULTS157 patients were identified. After exclusion a total of 125 patients were included from analysis. The mean PRS for trainees(0.34 g/min) was found to be lower than the mean PRS for consultants(0.41 g/min). The operating urologist's PRS was not observed to be related to the number of TURPs that they performed during the period of the study. The trainee vs consultant means post-operative success rates(86.5% vs 90.5%) were comparable. The Trainees' patients did not suffer any significant complications as defined by the study. There was no clear relationship observed between PRS and the rate of significant post-operative complications or patients' 3-mo binary successful outcome. PRS was noted to increase with increasing intra-operative experience for both Trainees 1 and 2 when comparing the first half of their TURPs to their latter half.CONCLUSION Consultants have a higher PRS in comparison to trainees. There is no trend between PRS and significant post-operative complication rates or 3-mo outcomes.Jack Donati-Bourne Shahd Nour Emiliya Angova George Delves 2019World Journal of Clinical Urology2019,8,1:0
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