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| 1 | Influence of H pylori on plasma ghrelin in patients without atrophic gastritis显示文摘AIM:To determine the association between H pylori infection and serum ghrelin levels in patients without atrophic gastritis.METHODS:Fifty consecutive patients(24 males and 26 females)with either H pylori-positive gastritis(n = 34)or H pylori-negative gastritis(n = 16)with normal gastric acid secretion determined by 24-h pHmetry and without atrophic gastritis in histopathology were enrolled in this study.Thirty-four H pylori-infected patients were treated with triple therapy consisting of a daily regimen of 30 mg lansoprazole bid,1 g amoxicillin bid and 500 mg clarithromycin bid for 14 d,followed by an additional 4 wk of 30 mg lansoprazol treatment.H pylori infection was eradicated in 23 of 34(67.6%)patients.H pylori-positive patients were given eradication therapy.Gastric acidity was determined via intragastric pH catethers.Serum ghrelin was measured by radioimmunoassay(RIA).RESULTS:There was no signifficant difference in plasma ghrelin levels between H pylori-positive and H pylori-negative groups(81.10 ± 162.66 ng/L vs 76.51 ± 122.94 ng/L).In addition,there was no significant difference in plasma ghrelin levels and gastric acidity levels measured before and 3 mo after the eradication therapy.CONCLUSION:H pylori infection does not influence ghrelin secretion in patients with chronic gastritis without atrophic gastritis. | Mehmet Cindoruk Ilhan Yetkin Serpil Muge Deger Tarkan Karakan Erdal Kan Selahattin Unal | 2007 | World Journal of Gastroenterology2007，13，10： | 13 |
| 2 | Effect of harmless acute pancreatitis score, red cell distribution width and neutrophil/lymphocyte ratio on the mortality of patients with nontraumatic acute pancreatitis at the emergency department显示文摘BACKGROUND: Harmless acute pancreatitis score(HAPS), neutrophile/lymphocyte ratio and red blood cell distribution width(RDW) are used to determine the early prognosis of patients diagnosed with nontraumatic acute pancreatitis in the emergency department(ED).METHODS: Patients diagnosed with acute pancreatitis(K 85.9) in the ED according to the ICD10 coding during one year were included in the study. Patients with chronic pancreatitis and those who had missing data in their files were excluded from the study. Patients who did not have computed tomography(CT) in the ED were not included in the study.RESULTS: Ultimately, 322 patients were included in the study. The median age of the patients was 53.1(IQR=36–64). Of the patients, 68.1%(n=226) had etiological causes of the biliary tract. The mortality rate of these patients within the first 48 hours was 4.3%(n=14). In the logistic regression analysis performed by using Balthazar classification, HAPS score, RDW, neutrophile/lymphocyte ratio, age, diabetes mellitus and systolic blood pressure, the only independent variable in determining mortality was assigned as Balthazar classification(OR: 15; 95% CI: 3.5 to 64.4).CONCLUSIONS: HAPS, neutrophile/lymphocyte ratio and RDW were not effective in determining the mortality of nontraumatic acute pancreatitis cases within the first 48 hours. The only independent variable for determining the mortality was Balthazar classifi cation. | Bedia Gülen Ertan Sonmez Serpil Yaylaci Mustafa Serinken Cenker Eken Ali Dur Figen Tunali Turkdogan ?zgür S?güt | 2015 | World Journal of Emergency Medicine2015，6，1： | 13 |
| 3 | Imatinib response of gastrointestinal stromal tumor patients with germline mutation on KIT exon 13:A family report显示文摘Familial gastrointestinal stromal tumor(GIST) is a rare autosomal dominant disorder associated with mutations in the KIT gene in the majority of cases. Although, exon 11 appears to be the hot spot region for approximately 95% of germline mutations, pathogenic variations have also been identified in exon 8, 13 and 17. Exon 13 germline mutations are extremely rare amongst familial GISTs and seven families with a germline mutation have been reported to date. Moreover, the role of imatinib mesylate in this rare familiar settings is not completely known so far. We describe here clinical, imaging, pathological and genetic findings of a family with four affected members; grandmother, his son and two grand-sons having a germline gain-of-function mutation of KIT in exon 13 and discuss the imatinib mesylate treatment surveillance outcomes towards disease management. | Gulgun Engin Serpil Eraslan Hülya Kayserili Yersu Kapran Haluk Akman Ali Akyuz Nuri Faruk Aykan | 2017 | World Journal of Radiology2017，9，9： | 3 |
| 4 | Vanishing bile duct and Stevens-Johnson syndrome associated with ciprofloxacin treated with tacrolimus显示文摘Stevens-Johnson syndrome (SJS) is a serious and potentially life-threatening disease. Vanishing bile duct syndrome (VBDS) is a rare cause of progressive cholestasis. Both syndromes are mostly related with drugs. We report a case of a patient with ciprofloxacin-induced SJS and acute onset of VBDS, and reviewed the related literature. It is the fi rst case of ciprofloxacin-induced VBDS successfully treated with tacrolimus. This case reminds physicians of the importance of drug reactions, their severity, techniques for diagnosis and methods of management. | Gokhan Okan Serpil Yaylaci Onder Peker Sabahattin Kaymakoglu Murat Saruc | 2008 | World Journal of Gastroenterology2008，14，29： | 3 |
| 5 | Gastroesophageal reflux in asymptomatic obese subjects:An esophageal impedance-pH study显示文摘AIM:To investigate the relationship between reflux and body mass index(BMI) in the asymptomatic obese population using the impedance-p H technique.METHODS:Gastroesophageal reflux is frequent in the obese population.However,the relationship between acid reflux and BMI in asymptomatic obese people is unclear.Forty-six obese(BMI > 25 kg/m2) people were enrolled in this prospective study.We evaluated the demographic findings and 24-h impedance p H values of the whole group.Gas,acid(p H < 4),weak acid(p H = 4-7) and weak alkaline(p H ≥ 7) reflux parameters were analyzed.RESULTS:The mean age of patients was 49.47±12.24 years,and half of them were men.The mean BMI was 30.64±3.95 kg/m2(25.14-45.58 kg/m2).BMI of 23 was over 30 kg/m2.Seventeen patients had a comorbidity(hypertension,diabetes mellitus,or ischemic heart disease).Endoscopic examination revealed esophagitis in 13 of the 28 subjects(10Grade A,3 Grade B).The subjects were divided into two groups according to BMI(<30 and>30 kg/m2).Demographic and endoscopic findings,and impedance results were similar in these two groups.However,there was a positive correlation between BMI and total and supine p H<4 episodes(P=0.002,r=0.414;P=0.000,r=0.542),p H<4 reflux time(P=0.015,r=0.319;P=0.003,r=0.403),and De Meester score(P=0.012,r=0.333).CONCLUSION:Acid reflux is correlated with BMI in asymptomatic obese individuals. | Filiz Akyüz Ahmet Uyanikoglu Fatih Ermis Serpil Arici ümit Akyüz Divison of Gastroenterology Department of Internal Medicine Faculty of Medicine Yeditepe University Bülent Baran Binnur Pinarbasi Nurdan Gul | 2015 | World Journal of Gastroenterology2015，21，10： | 3 |
| 6 | Recent innovation in benchmark rates (BMR):evidence from influential factors on Turkish Lira Overnight Reference Interest Rate with machine learning algorithms显示文摘Some countries have announced national benchmark rates,while others have been working on the recent trend in which the London Interbank Offered Rate will be retired at the end of 2021.Considering that Turkey announced the Turkish Lira Overnight Reference Interest Rate(TLREF),this study examines the determinants of TLREF.In this context,three global determinants,five country-level macroeconomic determinants,and the COVID-19 pandemic are considered by using daily data between December 28,2018,and December 31,2020,by performing machine learning algorithms and Ordinary Least Square.The empirical results show that(1)the most significant determinant is the amount of securities bought by Central Banks;(2)country-level macroeconomic factors have a higher impact whereas global factors are less important,and the pandemic does not have a significant effect;(3)Random Forest is the most accurate prediction model.Taking action by considering the study’s findings can help support economic growth by achieving low-level benchmark rates. | Öer Depren Mustafa Tevfik Kartal Serpil KılıçDepren | 2021 | Financial Innovation2021，7，1： | 2 |
| 7 | The diagnostic value of non-invasive tests for the evaluation of liver fibrosis in chronic hepatitis B patients显示文摘 | Serpil Erdogan Halef Okan Dogan Sevilay Sezer Sema Uysal Esra Ozhamam Serra Kayacetin Yuksel Koca | 2013 | Scandinavian Journal of Clinical & Laboratory Investigation2013，，4： | 2 |
| 8 | Impact of COVID-19 on the food supply chain显示文摘A pandemic is not a new event encountered in the history of humanity because mankind has faced various pandemics in history. The common point of pandemics is their serious negative effects on the global economy. Considering the food supply chain, one of the most important sectors of the economy, it has been seen that COVID-19 has an impact on the whole process from the field to the consumer. In the light of recent challenges in food supply chain, there is now considerable concern about food production, processing, distribution, and demand. COVID-19 resulted in the movement restrictions of workers, changes in demand of consumers, closure of food production facilities, restricted food trade policies, and financial pressures in food supply chain. Therefore, governments should facilitate the movement of workers and agri-food products. In addition, small farmers or vulnerable people should be supported financially. Facilities should change the working conditions and maintain the health and safety of employees by altering safety measures. Food protectionist policies should be avoided to prevent an increase in food prices. In conclusion, each country must realize the severity of the situation and sometimes should tighten or loosen the measures according to the spread of the pandemic. The supply chain also should be flexible enough to respond to the challenges in the food supply chain. The purpose of this review is to evaluate the impact of COVID-19 on the agriculture and food sector and to summarize the recommendations required to reduce and control the effect of the pandemic. | Serpil Aday Mehmet Seckin Aday | 2020 | Food Quality and Safety2020，4，4： | 2 |
| 9 | Impressive effect of immobilization conditions on the catalytic activity and enantioselectivity of Candida rugosalipase toward S- Naproxen production 显示文摘 | Serpil Takac Mehmet Bakkal | 2007 | Process Biochemistry2007，，42： | 1 |
| 10 | The comparison of pul- monary functions in open versus laparoscopic cholecystee- tomy显示文摘 | Osman Y Fusun A Serpil A | 2009 | J Pak Med Assoc2009，59，4： | 1 |
| 11 | Degradation of organophosphorus pesticides in wheat during cookie processing显示文摘 | Umran Uygun Berrin Senoz Serpil ?ztürk Hamit Koksel | 2009 | Food Chemistry2009，，2： | 1 |
| 12 | Antioxidant responses to oxidant-mediated lung diseases显示文摘 | Comhair Serpil CE | 2002 | Am J Physiol Lung Cell Mol Physiol2002，283，2： | 1 |
| 13 | Predicting the cookie quality of flours by using Mixolab?显示文摘 | Serpil Ozturk Kevser Kahraman Bengihan Tiftik Hamit Koksel | 2008 | European Food Research and Technology2008，，5： | 1 |
| 14 | Numerical study of flow around an inclind elliptic cylinder oscillating in line with anincident uniform flow显示文摘 | Serpil Kocabiyik Alessio S J D D | 2004 | European Journal of Mechanics B/Fluids2004，，23： | 1 |
| 15 | Is obesity a risk factor for psychopathology among adolescents? 显示文摘 | Serpil E Nurcan C Muge T | 2004 | Pediatr Int2004，46，： | 1 |
| 16 | In vitro amoebicidal activities of Teucrium polium and T. chamaedrys on Acanthamoeba castellanii trophozoites and cysts显示文摘 | Bektas Tepe Erdogan Malatyali Serpil Degerli Seyda Berk | 2012 | Parasitology Research2012，，： | 1 |
| 17 | Degradation of organophosphorus pesticides in wheat during cookie processing显示文摘 | Umran U Berrin S Serpil O | 2009 | Food Chemistry2009，117，2： | 1 |
| 18 | Bioconversion of trans-cinnamic acid to L-phenylalanine by L-phenylalanine ammonia lyase of Rhodotorula glutinis : parameters and kinetics 显示文摘 | Serpil T Akay B Tuncer H O | 1995 | Enzyme Microb Technol1995，17，： | 1 |
| 19 | The association between the DMFS index and levels of salivary StreptococcUS mutans and lactobacilli of subjects living in Er- zurum, Turkey显示文摘 | Serpil Karaolanolu Nilgan AkgUl Hayati Murat Akgtll | 2010 | Dent Sci2010，5，2： | 1 |
| 20 | Plasma homocysteine concentrations and serum lipid profile as atherosclerotic risk factors in subclinical hypothyroidism显示文摘 | Serpil Turhan Sevilay Sezer Gonul Erden Ali Guctekin Fatma Ucar Zeynep Ginis Ozlem Ozturk Sezin Bingol | 2008 | Annals of Saudi Medicine2008，，2： | 1 |
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