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139篇 您的检索式:作者名="Scotton"
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1会话中身份的协调:标记性和代码选择理论显示文摘1.引言这篇论文提出一套支配会话中身份协调的准则。本文的论点是,交谈者所作的语言代码选择,用协调准则来解释,就能得出说话人与受话人对交谈的权利和义务方面的会话隐涵。本文的主要目的是提出一种解释语言代码选择变异的模式。这种模式赖以存在的前提是,会话参与者以自然的标记理论来解释所有的代码选择现象,即作为他们讯递能力(com-municative competence,Hymes,1972)的一部分,说话人依照他们言语社团的规范来辨别代码选择是无标记的还是有标记的。按照社团的规范。Carol Myers Scotton 姚远 1990当代语言学1990,,1:4
2Impact of age on feasibility and short-term outcomes of ERAS after laparoscopic colorectal resection显示文摘BACKGROUND There is still large debate on feasibility and advantages of fast-track protocols in elderly population after colorectal surgery.AIM To investigate the impact of age on feasibility and short-term results of enhanced recovery protocol(ERP)after laparoscopic colorectal resection.METHODS Data from 225 patients undergoing laparoscopic colorectal resection and ERP between March 2014 and July 2018 were retrospectively analyzed.Three groups were considered according to patients’age:Group A,65 years old or less,Group B,66 to 75 years old and Group C,76 years old or more.Clinic and pathological data were compared amongst groups together with post-operative outcomes including post-operative overall and surgery-specific complications,mortality and readmission rate.Differences in post-operative length of stay and adherence to ERP’s items were evaluated in the three study groups.RESULTS Among the 225 patients,112 belonged to Group A,57 to Group B and 56 to Group C.Thirty-day overall morbidity was 32.9%whilst mortality was nihil.Though the percentage of complications progressively increased with age(25.9%vs 36.8%vs 42.9%),no differences were observed in the rate of major complications(4.5%vs 3.5%vs 1.8%),prolonged post-operative ileus(6.2%vs 12.2%vs 10.7%)and anastomotic leak(2.7%vs 1.8%vs 1.8%).Significant differences in recovery outcomes between groups were observed such as delayed urinary catheter removal(P=0.032)and autonomous deambulation(P=0.013)in elderly patients.Although discharge criteria were achieved later in older patients(3 d vs 3 d vs 4 d,P=0.040),post-operative length of stay was similar in the 3 groups(5 d vs 6 d vs 6 d).CONCLUSION ERPs can be successfully and safely applied in elderly undergoing laparoscopic colorectal resection.Corrado Pedrazzani Cristian Conti Giulia Turri Enrico Lazzarini Marzia Tripepi Giovanni Scotton Matteo Rivelli Alfredo Guglielmi 2019World Journal of Gastrointestinal Surgery2019,11,10:4
3Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil.Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari 2019World Journal of Gastroenterology2019,25,38:2
4Epithelial cancer cell migration a role for chemokine receptors显示文摘SCOTTON CJ WILSON JL MELLIKEN D 2001Cancer Res2001,61,13:1
5Early linezolid-associat-ed lactic acidosis in a patient treated for tuberculous spondylo-discitis显示文摘Scotton P Fuser R Torresan S 2008Infection2008,36,:1
6Molecular targets in pulmonary fibrosis:the myofibroblast in focus显示文摘Scotton CJ Chambers RC 0,,:1
7Epithelial cancer cell migration:a role for chemokine receptors显示文摘Scotton CJ 2001Cancer Res2001,61,13:1
8Molecular targets in pulmonary fibrosis: the myofibroblast in focus 显示文摘Scotton C J Chambers RC 2007Chest2007,132,4:1
9Bone marrow stem cells expressing keratinocyte growth factor via an inducible lentivirus protects against bleomycin-induced pulmonary fibrosis 显示文摘Aguilar S Scotton C J McNuhy K 2009PLoS One2009,4,11:1
10Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer显示文摘Scotton CJ Wilson JL Scott K 2002Cancer Res2002,62,:1
11Ducheime Muscular Dys- trophy: From Diagnosis to Therapy显示文摘Falzarano MS Scotton C Passarelli C 2015Molecules2015,20,18:1
12Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer 显示文摘Scotton CJ Wilson JL Scott K 2002Cancer Res2002,62,:1
13Epithelial cancer cell migration : a role for chemokine receptors ? 显示文摘Scotton C J Wilson JL Milliken D 2001Cancer Res2001,61,13:1
14Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites 显示文摘Milliken D Scotton C Raju S 2002Clin Cancer Res2002,8,4:1
15Human ovarian cancer : Multiple actions of the chemokine CXCL12 on epithelial turner cells in human ovarian cancer显示文摘Scotton C J Wilson J L Scott K 2002Cancer Res2002,62,20:1
16Novel therapeutic approachesfor pulmonary fibrosis 显示文摘Datta A Scotton CJ Chambers RC 2011Br J Pharmacol2011,163,1:1
17Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer 显示文摘Scotton C J Wilson J L Scott K 2002Cancer Res2002,62,20:1
18Analysis of cc chemokine and chemokine receptor expression in solid ovarian tumours显示文摘Milliken D Scotton C Raju S 2002Clin Cancer Res2002,8,4:1
19Coagulation signalling following tissue injury: focus on the role of factor Xa 显示文摘Krupiczoic M A Scotton C J Chambers R C 2008Int J Biochem Cell Biol2008,40,67:1
20Molecular targets in pulmonary fibrosis: The myofibroblast in focus 显示文摘Scotton C J Chambers R C 2007Chest2007,132,:1
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