5篇
您的检索式：作者名="Satoshi Minoshima"
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| 1 | Anatomic Standardization: Lin- ear Scaling and nonlinear warping of functional brain images 显示文摘 | Satoshi Minoshima Robert A | 1994 | J Nucl Med1994，35，9： | 1 |
| 2 | Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer’s disease: a PET follow-up study显示文摘 | Alexander Drzezga Nicola Lautenschlager Hartwig Siebner Matthias Riemenschneider Frode Willoch Satoshi Minoshima Markus Schwaiger Alexander Kurz | 2003 | European Journal of Nuclear Medicine and Molecular Imaging2003，，8： | 1 |
| 3 | Gastric distention correlates with activation of multiple cortical and subcortical regions显示文摘 | Uri Ladabaum Satoshi Minoshima William L. Hasler Donna Cross William D. Chey Chung Owyang | 2001 | Gastroenterology2001，，2： | 1 |
| 4 | Magnetic resonance imaging-guided focused ultrasound to increase localized blood-spinal cord barrier permeability显示文摘Spinal cord injury(SCI) affects thousands of people every year in the USA, and most patients are left with some permanent paralysis. Therapeutic options are limited and only modestly affect outcome. To address this issue, we used magnetic resonance imaging-guided focused ultrasound(MRg FUS) as a non-invasive approach to increase permeability in the blood-spinal cord barrier(BSCB). We hypothesize that localized, controlled sonoporation of the BSCB by MRg FUS will aid delivery of therapeutics to the injury. Here, we report our preliminary findings for the ability of MRg FUS to increase BSCB permeability in the thoracic spinal cord of a normal rat model. First, an excised portion of normal rat spinal column was used to characterize the acoustic field and to estimate the insertion losses that could be expected in an MRg FUS blood spinal cord barrier opening. Then, in normal rats, MRg FUS was applied in combination with intravenously administered microbubbles to the spinal cord region. Permeability of the BSCB was indicated as signal enhancement by contrast administered prior to T1-weighted magnetic resonance imaging and verified by Evans blue dye. Neurological testing using the Basso, Beattie, and Breshnahan scale and the ladder walk was normal in 8 of 10 rats tested. Two rats showed minor impairment indicating need for further refinement of parameters. No gross tissue damage was evident by histology. In this study, we have opened successfully the blood spinal cord barrier in the thoracic region of the normal rat spine using magnetic resonance-guided focused ultrasound combined with microbubbles. | Allison H.Payne Gregory W.Hawryluk Yoshimi Anzai Henrik Odéen Megan A.Ostlie Ethan C.Reichert Amanda J.Stump Satoshi Minoshima Donna J.Cross | 2017 | Neural Regeneration Research2017，12，12： | 1 |
| 5 | Prediction of Hyperperfusion After Carotid Endarterectomy by Brain SPECT Analysis With Semiquantitative Statistical Mapping Method显示文摘 | Kohkichi Hosoda Tetsuro Kawaguchi Kazunari Ishii Satoshi Minoshima Yuji Shibata Masaki Iwakura Shigeo Ishiguro Eiji Kohmura | 2003 | Stroke: Journal of the American Heart Association2003，，5： | 1 |
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