| 7 | Sensibility of male rats fertility against olive oil, Nigella sativa oil and pomegranate extract显示文摘Objective:To clarify the modulatory effects of daily consumption of pomegranate extract(PE),olive oil(OO)andNagilla sativaoil(NSO)on antioxidant activity,sperm quality and pituitary-testicular axis of adult male wistar rats.Methods:Thirty-two adult male Wistar rats were dividedinto four equal groups,eight rats each.Using rat gastric tubes,1.0 mL distilled water,1.0 mL PE,0.4mL NSO and 0.4 mL OO were orally administered daily for 6 weeks in the first,second,third andfourth groups,respectively.Reproductive organs,body weight,sperm criteria,testosterone,FSH,LH,inhibin-B,lipid peroxidation,and antioxidant enzyme activities were investigated.At the endof the study protocol,analyses occurred at the same time.Data were analysed by ANOVA test and P<0.05 was considered to be a significant value.Results:In all studied groups,malondialdehydelevel was significantly decreased accompanied with an increases in glutathione peroxidase andglutathione.Rats treated with PE showed an increase in catalase activities accompanied withan increase in sperm concentration which was also observed in NSO group.In PE treated group,sperm motility was also increased accompanied with decreased abnormal sperm rate.NSO,OOand PE treated groups shows an insignificant effect on testosterone,inhibin-B,FSH and LH incomparison with control group.Conclusions:These results show that administration of PE,NSOand OO could modify sperm characteristics and antioxidant activity of adult male wistar rats. | Sherif W. Mansour Sibghatullah Sangi Sree Harsha Mueen A. Khaleel A. R. N. Ibrahim | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员