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| 1 | Bone marrow-derived mesenchymal stem cells versus adipose-derived mesenchymal stem cells for peripheral nerve regeneration显示文摘Studies have confirmed that bone marrow-derived mesenchymal stem cells(MSCs) can be used for treatment of several nervous system diseases. However, isolation of bone marrow-derived MSCs(BMSCs) is an invasive and painful process and the yield is very low. Therefore, there is a need to search for other alterative stem cell sources. Adipose-derived MSCs(ADSCs) have phenotypic and gene expression profiles similar to those of BMSCs. The production of ADSCs is greater than that of BMSCs, and ADSCs proliferate faster than BMSCs. To compare the effects of venous grafts containing BMSCs or ADSCs on sciatic nerve injury, in this study, rats were randomly divided into four groups: sham(only sciatic nerve exposed), Matrigel(MG; sciatic nerve injury + intravenous transplantation of MG vehicle), ADSCs(sciatic nerve injury + intravenous MG containing ADSCs), and BMSCs(sciatic nerve injury + intravenous MG containing BMSCs) groups. Sciatic functional index was calculated to evaluate the function of injured sciatic nerve. Morphologic characteristics of nerves distal to the lesion were observed by toluidine blue staining. Spinal motor neurons labeled with Fluoro-Gold were quantitatively assessed. Compared with sham-operated rats, sciatic functional index was lower, the density of small-diameter fibers was significantly increased, and the number of motor neurons significantly decreased in rats with sciatic nerve injury. Neither ADSCs nor BMSCs significantly improved the sciatic nerve function of rats with sciatic nerve injury, increased fiber density, fiber diameters, axonal diameters, myelin sheath thickness, and G ratios(axonal diameter/fiber diameter ratios) in the sciatic nerve distal to the lesion site. There was no significant difference in the number of spinal motor neurons among ADSCs, BMSCs and MG groups. These results suggest that neither BMSCs nor ADSCs provide satisfactory results for peripheral nerve repair when using MG as the conductor for engraftment. | Marcela Fernandes Sandra Gomes Valente Rodrigo Guerra Sabongi Joao Baptista Gomes dos Santos Vilnei Mattioli Leite Henning Ulrich Arthur Andrade Nery Maria José da Silva Fernandes | 2018 | Neural Regeneration Research2018，13，1： | 10 |
| 2 | Removal of chromium from electroplating industry effluents by ion exchange resins显示文摘 | Sofia A. Cavaco Sandra Fernandes Margarida M. Quina Licínio M. Ferreira | 2007 | Journal of Hazardous Materials2007，，3： | 2 |
| 3 | 显示文摘 | Susete Fernandes Sandra G Correia | 2002 | Polym Int2002，51，8： | 1 |
| 4 | 显示文摘 | Susete Fernandes Sandra G Correia | 2001 | Polym Int2001，50，： | 1 |
| 5 | Detection of Leishmania ( Leishmania ) amazonensis and Leishmania ( Leishmania ) infantum chagasi in Brazilian bats显示文摘 | Elisa San Martin Mouriz Savani Marilene Fernandes de Almeida Maria Cecília Gibrail de Oliveira Camargo Sandra Regina Nicoletti D’Auria Miriam Martos Sodré Silva Maria Lúcia de Oliveira Débora Sacramento | 2009 | Veterinary Parasitology2009，，1： | 1 |
| 6 | 13-Carotene from cassava (Manihot es-culenta Crantz) leaves improves Vitamin A status in rats显示文摘 | Egle Machado de Almeida Siqueira Sandra Fernandes Arrnda Ro-drigo Martins de Vargas | 2007 | Comparative Biochemistry and Physiology Part C2007，146，2： | 1 |
| 7 | 显示文摘 | Maria M Marques Susete Fernandes Sandra G Correla | 2001 | Polym lnt2001，50，： | 1 |
| 8 | Agnuside Reduces Visceral Adipocyte Size,Improves Insulin Sensitivity and Reverses Hepatic Steatosis in Ovariectomized Rats显示文摘This study aimed to investigate the effects of agnuside(AGN),a phytoestrogen in Vitex agnus-castus,on cellular and metabolic alterations induced by ovariectomy in rats.Ovariectomized(OVX)Wistar rats were used as an animal model of postmenopausal metabolic syndrome.The visceral and subcutaneous adipocyte sizes,the peripheral insulin sensitivity and the occurrence of nonalcoholic fatty liver disease(NAFLD)and liver oxidative damage were evaluated.The results were compared with those obtained from control rats(sham-operated)and OVX rats treated daily with AGN.Obese OVX rats exhibited visceral adipocyte hypertrophy and developed glucose intolerance,hyperinsulinemia,NAFLD and dyslipidemia.AGN exerted beneficial effects on several metabolic parameters in OVX rats,including the improvement in glucose intolerance,hyperinsulinemia and NAFLD.Besides,AGN promoted a general improvement in the liver redox state.Although the reduction of the mesenteric adipocyte size is very likely to be an important mode of action of AGN,some actions of AGN could also involve the interaction with estrogen receptors. | Franciele Neves Moreno Eduardo Hideo Gilglioni Rosangela Fernandes Garcia Naiara Cristina Lucredi Sandra Mara Ferreira Nilton Almeida Brito Marcia do Nascimento Brito Emy Luiza Ishii-Iwamoto Clairce Luzia Salgueiro-Pagadigorria | 2019 | Journal of Pharmacy and Pharmacology2019，7，4： | 0 |
| 9 | Feeding ecology of a highly aerial bird during its long breeding season显示文摘Pallid Swifts(Apus pallidus),as other swifts,are birds extremely adapted to an aerial lifestyle,showing unique adaptations that allow them to fly almost continuously.The diet of these non-stopping high-altitudinal aerial birds has been mostly studied through techniques that fail to produce highly resolved prey identifications,and for that have been replaced by molecular techniques,such as DNA metabarcoding.Faecal samples of Pallid Swifts were monthly collected from a colony in the north of Portugal during the breeding season.DNA from the faecal samples was used to sex the birds and to identify the arthropods present in the diet through DNA metabarcoding.From the detected prey items,74 families were identified belonging to 16 orders,with Hymenoptera and Hemiptera being the most frequently consumed.There were seasonal variations in diet richness,composition and prey size.Regarding the diet of males and females,although no differences were found between the diet of males and females in terms of composition and richness,there were differences in the size of arthropods preyed by the different sexes,with males feeding on larger arthropods.The large seasonal variation in Pallid Swifts’diet during the breeding season is probably a result of spatiotemporal variation in aerial prey,of which swifts likely predate opportunistically.Although no significant differences were detected in diet richness and composition between sexes,the fact that males consumed larger prey may suggest the existence of sexual dietary segregation in this group of birds.At last,several pest species were found in these swifts’diet,which,if studied through DNA metabarcoding,can be used to monitor small arthropods,including airborne pests. | Sandra Fernandes Vanessa A.Mata Luis P.da Silva | 2023 | Avian Research2023，14，1： | 0 |
| 10 | Cardiovascular rehabilitation in patients aged 70-year-old or older:benefits on functional capacity,physical activity and metabolic profile in younger vs.older patients显示文摘Background The benefits of exercise-based cardiac rehabilitation(EBCR)programs in post-acute myocardial infarction(AMI)patients have been demonstrated.Our aim was to assess the impact of EBCR in³70-years-old vs.younger post-AMI patients.Methods We retrospectively evaluated patients who underwent a supervised EBCR protocol,twice a week during 6-12 weeks.We evaluated changes in several outcomes based on pre-and post-CRP assessments.Results Of a total of 1607 patients,333(21%)were³70-years-old.After the EBCR,an overall improvement on functional capacity,daily physical activity,lipid profile,body mass index,glycated hemoglobin(HbA1c),N-terminal pro-brain natriuretic peptide(NT-pro-BNP)and C-reactive protein was observed in both younger and older patients(P<0.05).Older patients showed a smaller benefit on the increment of daily physical activity and lipid profile improvement,but a larger reduction in NT-pro-BNP.In the multivariate analysis,only improvements on daily physical activity and HbA1c were dependent on age.Conclusion As their younger counterparts,older patients,significantly improved functional capacity,metabolic parameters and level of daily physical activity after EBCR. | Marta Fontes-Oliveira Maria Trêpa Patrícia Rodrigues Preza Fernandes Sandra Magalhães Sofia Cabral Mário Santos Severo Torres | 2020 | Journal of Geriatric Cardiology2020，17，9： | 0 |
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