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| 1 | Management of pancreaticobiliary disease using a new intra-ductal endoscope:The Texas experience显示文摘AIM:To evaluate a new single-operator mini-endoscope, Spyglass,for its performance,feasibility and safety in the management of pancreaticobiliary disease. METHODS:In a multicenter retrospective analysis of patients undergoing intraductal endoscopy,we evaluated 128 patients(71 men,mean age 57.6 years).Indications were therapeutic(TX)in 72(56%) and diagnostic(DX)in 56(44%). RESULTS:Peroral endoscopy was performed in 121 and percutaneous in seven.TX indications included CBD stones in 41,PD stones in six,and biliary strictures in 25.DX indications included abnormal LFT’s in 15, abnormal imaging in 38 and cholangiocarcinoma staging in three.Visualization of the stone(s)was considered good in 31,fair in six,and poor in four. Advancement of the electrohydraulic lithotripsy probe was not possible in three patients and proper targeting of the lesion was partial in four patients.A holmium laser was used successfully in three patients.Ductal clearance was achieved in 37 patients after one procedure and in four patients after two procedures.Diagnosis of biliary strictures was modified in 20/29 and confirmed to be malignant in 10/23.Of the modified patients,no diagnosis was available in 17.Spyglass demonstrated malignancy in 8/17 and non-malignancy in nine.Suspected pathology by imaging studies and abnormal LFT’s was modified in 43/63(66%).Staging of cholangiocarcinoma demonstrated multicentric cholangiocarcinoma in 2/3.There was no morbidity associated with the use of Spyglass. CONCLUSION:Spyglass Spyscopeis a first generation, single operator miniature endoscope that can evaluate and treat various biliary and pancreatic tract diseases. | Douglas S Fishman Paul R Tarnasky Sandeep N Patel Isaac Raijman | 2009 | World Journal of Gastroenterology2009，15，11： | 22 |
| 2 | Over expression of resistin in adipose tissue of the obese induces insulin resistance显示文摘AIM: To compare resistin mRNA expression in subcutaneous adipose tissue (SAT) and its correlation with insulin resistance (IR) in postmenopausal obese women. METHODS: A total of 68 postmenopausal women (non obese = 34 and obese = 34) were enrolled for the study. The women of the two groups were age matched (49-70 years). Fasting blood samples were collected at admission and abdominal SAT was obtained during surgery for gall bladder stones or hysterectomy. Physical parameters [age, height, weight, body mass index (BMI)] were measured. Biochemical (plasma insulin and plasma glucose) parameters were estimated by enzymatic methods. RNA was isolated by the Trizol method.SAT resistin mRNA expression was done by real time- reverse transcription polymerase chain reaction (RT-PCR) by using Quanti Tect SYBR Green RT-PCR master mix. Data was analyzed using independent Student's t test, correlation and simple linear regression analysis. RESULTS: The mean weight (52.81 ± 8.04 kg vs 79.56 ± 9.91 kg; P < 0.001), BMI (20.23 ± 3.05 kg/m 2 vs 32.19 ± 4.86 kg/m 2 ; P < 0.001), insulin (8.47 ± 3.24 U/mL vs 14.67 ± 2.18 U/mL; P < 0.001), glucose (97.44 ± 11.31 mg/dL vs 109.67 ± 8.02 mg/dL; P < 0.001) and homeostasis model assessment index (2.01 ± 0.73 vs 3.96 ± 0.61; P < 0.001) were significantly higher in postmenopausal obese women compared to postmenopausal non obese women. The mean serum resistin level was also significantly higher in postmeno-pausal obese women compared to postmenopausal non obese women (9.05 ± 5.15 vs 13.92 ± 6.32, P < 0.001). Furthermore, the mean SAT resistin mRNA expression was also significantly (0.023 ± 0.008 vs 0.036 ± 0.009; P < 0.001) higher and over expressed 1.62 fold (upregulated) in postmenopausal obese women compared to postmenopausal non obese women. In postmeno-pausal obese women, the relative SAT resistin mRNA expression showed positive (direct) and significant correlation with BMI (r = 0.78, P < 0.001) and serum resistin (r = 0.76, P < 0.001). Furthermore, the SAT resistin mRNA expression in postmenopausal obese women also showed significant and direct association (r = 0.45, P < 0.01) with IR, while in postmenopausal non obese women it did not show any association (r = -0.04, P > 0.05). CONCLUSION: Increased SAT resistin mRNA expres-sion probably leads to inducing insulin resistance and thus may be associated with obesity-related disorders in postmenopausal obese women. | Sadashiv Sunita Tiwari S Dhananjai Bhola N Paul Sandeep Kumar Abhijit Chandra Mahendra PS Negi | 2012 | World Journal of Diabetes2012，3，7： | 10 |
| 3 | 反相高效液相色谱法同时检测片剂中的头孢呋辛酯及奥硝唑(英文)显示文摘A simple,accurate and sensitive reversed-phase high performance liquid chromatographic(RP-HPLC)method for the simultaneous determination of cefuroxime axetil and ornidazole in combined tablet dosage form has been developed.The method was performed with a HiQ-SiL C18 column(250 mm×4.6 mm)and photodiode array(PDA)detector,using 0.01 mol/L potassium dihydrogen orthophosphate-methanol(56∶44,v/v)as the mobile phase and tinidazole as the internal standard.Beer's law obeys in the concentration ranges of 5-25 μg/mL and 10-50 μg/mL for cefuroxime axetil and ornidazole,respectively.The method has been successfully validated statistically and applied for the analysis of the drugs in pharmaceutical formulation. | RANJANE Poonam N GANDHI Santosh V KADUKAR Sayali S RANHER Sandeep S | 2008 | 色谱2008，26，6： | 4 |
| 4 | Hexaalkoxytricycloquinazolines: New discot- ic liquid crystals 显示文摘 | SANDEEP K ILI~N J | 1993 | J Org Chem1993，58，15： | 1 |
| 5 | Can hormone replacement therapy priorto oocyte donation cycle in women with premature ovarian failure improve pregnancy rate显示文摘 | Naredi N Sandeep K Jamwal V D S | 2013 | Medical Journal Armed Forces India2013，69，4： | 1 |
| 6 | Powerful bactericidal and sterilizing activity of a regimen containing PA-824, moxifloxacin, and pyrazinamide in a murine model of tuberculosis显示文摘 | Eric N Sandeep T Rokeya T | 2008 | Antimicrob Agents Chemother2008，52，4： | 1 |
| 7 | A treat- ment plant receiving waste water from multiple bulk drug manufacturers is a reservoir for highly multi-drug resist- ant integron-bearing bacteria 显示文摘 | Marathe N P Viduthalai R R Sandeep A W | 2013 | PLoS ONE2013，8，77： | 1 |
| 8 | A recurrent network for dynamic system identification显示文摘 | Adwankar Sandeep Banavar Ravi N | 1997 | International Journal of System Science (S0020-7721)1997，28，12： | 1 |
| 9 | Chloro- form poisoning-a case report显示文摘 | SRIDHAR N KRISHNAKISHORE C SANDEEP Y | 2011 | Ren Fail2011，33，10： | 1 |
| 10 | Continuous Culture Biodegradation of Simazinee's Chemical Oxidation Products 显示文摘 | Sandeep S S Scott A W James N J | 1996 | Water Research1996，30，9： | 1 |
| 11 | Study of composition de- pendent structural, optical, and magnetic properties of Cu-doped Znl_x CdxS nanoparticles 显示文摘 | Kumar C Sonal S Sandeep N | | Journal of Applied Physics0，108，12： | 1 |
| 12 | Agenesis of premolar associated with submerged primary molar and a supernumerary premolar: an unusual case report显示文摘 | Nirmala SV Sandeep C Sivakumar N | 2012 | Contemp Clin Dent2012，3，1： | 1 |
| 13 | A new gene for resistance in rice to Asian rice gall midge (Orseolia oryzae Wood Mason) biotype 1 population at Raipur,India显示文摘 | Shrivastava M N Arvind Kumar Sandeep Bhandarkar | 2003 | Euphytica2003，130，1： | 1 |
| 14 | Catalytic performanceof nano crystalline HZSM-5 in ethanol to gasoline(ETG) reaction显示文摘 | NAGABHATLA V SANDEEP K S JITENDRA K PATA S DEVAKI N | 2012 | Fuel2012，95，1： | 1 |
| 15 | Surface electrostimulation of acupuncture points for sedation of critically ill patients in the intensive care unit-a pilot study 显示文摘 | Sandeep N Richard W Jones A | 2008 | Acup Med2008，26，1： | 1 |
| 16 | Monopulse MIMO radar for target tracking显示文摘 | Sandeep G and Arye N | 2011 | IEEE Transactions on Aerospace and Electronic Systems2011，47，1： | 1 |
| 17 | A two-location inventory model with transshipment and local decision making 显示文摘 | Rudi N Sandeep K David F P | 2001 | Management Science2001，47，12： | 1 |
| 18 | Biosensors as novel platforms for detection of food pathogens and allergens显示文摘 | SANDEEP KUMAR N D BARNELA M BHANJANA G el al | 2012 | BioNanoScience2012，2，4： | 1 |
| 19 | Can hormone replacement therapy prior to oocyte donation cycle in women with prema- ture ovarian failure improve pregnancy rate? 显示文摘 | Naredi N Sandeep K Jamwal VD | 2013 | Med J Armed Forces India2013，69，4： | 1 |
| 20 | Control of creep and shrinkage effects in steel concrete composite bridges with precast decks显示文摘 | Sandeep C Umesh P Ashok K N | 2009 | Journal of Bridge Engineering2009，14，5： | 1 |
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