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| 1 | Safety and success of precut biliary sphincterotomy: Is it linked to experience or expertise?显示文摘瞄准:决定成功的率和按规格裁切的复杂并发症胆汁的括约肌切开术(PBS ) 基于优先的经验并且到比较在 PBS 和标准内视镜的括约肌切开术(ES ) 之间的复杂并发症率。方法:回顾的评估有希望地在一个学术第三级的工作分派中心收集了非使随机化的数据。包括的学习没有 formal 在 PBS 训练的由单个 endoscopist 经历了 PBS 和 ES 的在一个八年的时期的所有病人。学习的主要结果措施是有到 ES 的复杂并发症的比较的 PBS 的成功和复杂并发症。结果:一个总数 2939 内视镜后退 cholangiopancreatographies (ERCP ) 在学习时期期间被执行,包括 818 (28%) ES 并且 150 (5%) PBS 过程。经由 PBS 的选择胆汁的管子在在 75% 病人的第一次尝试是成功的。管子被完成在一另外在一次随后的尝试(总数 87%) 的 13% 病人。从 PBS 的复杂并发症率比 ES 高是 45% ,但是没显著地不同[7%(10/50 ) 对 5%(38/818 ) , P = 0.29 ] 。任何一个从 PBS 的复杂并发症都不是严重的。向增加成功的一个重要趋势关于 endoscopist 存在 ?ˉs 在按规格裁切的第一次尝试(P = 0.0393,为趋势的 Cochran-Armitage 准确测试, Z =-1.7588) 。结论:尽管有在这种技术的特定的训练的缺乏, PBS 从另外的富有经验的中心与高成功率和类似于的复杂并发症率或不到报告被执行。这些结果建议内视镜的经验和也许天生的内视镜的技巧可以在这个过程的结果起一个重要作用。 | Lindsay S Robison Shyam Varadarajulu C Mel Wilcox | 2007 | World Journal of Gastroenterology2007，13，15： | 10 |
| 2 | NAT2 polymorphism in Omani gastric cancer patients-risk predisposition and clinicopathological associations显示文摘AIM: To study whether N-acetyltransferase 2 (NAT2) genotypes and phenotypes are associated with increased risk factor for gastric cancer in Omani patients and to study the clinico-pathological correlations and the prognostic signifi cance of NAT2.METHODS: Genomic DNA was extracted from peripheral blood of 100 gastric cancer patients and 100 control subjects. NAT2 genotyping was performed using DNA sequencing. The prognostic significance of NAT2 and other clinicopathological features was assessed by univariate and multivariate analyses.RESULTS: We observed no significant association between NAT2 genotypes and phenotypes and gastric cancer risk. The NAT2 phenotype polymorphisms and gastric cancer risk predisposition were not modified by concomitant H pylori infection and smoking. There was no significant association between NAT2 and clinicopathological features, and NAT2 had no independent prognostic signifi cance.CONCLUSION: In the current study, NAT2 genotypes and phenotypes are not associated with gastric cancer risk predisposition. Moreover NAT2 phenotypes had no clinicopathological associations or prognostic signif icance. | Mansour S Al-Moundhri Mohamed Al-Kindi Maryam Al-Nabhani Bassim Al-Bahrani Ikram A Burney Ali Al-Madhani Shyam S Ganguly Misbah Tanira | 2007 | World Journal of Gastroenterology2007，13，19： | 5 |
| 3 | Plasma cathepsin L:A prognostic marker for pancreatic cancer显示文摘AIM:To assess the prognostic significance of cathepsin L,a cysteine protease that degrades the peri-tumoral tissue,in patients with pancreatic cancer.METHODS:Plasma samples from 127 pancreatic cancer patients were analyzed for cathepsin L levels by ELISA.Out of these patients,25 underwent surgeryand their paraffin-embedded tissue was analyzed for cathepsin L expression by immunohistochemistry.Survival of patients and clinicopathological parameters was correlated with cathepsin L expression in plasma and tissue using appropriate statistical analysis.RESULTS:The mean(±SD)cathepsin L in plasma samples of pancreatic cancer patients was 5.98±2.5ng/m L that was significantly higher compared to the levels in healthy controls(3.83±0.45)or chronic pancreatitis patients(3.97±1.06).Using ROC curve,a cut-off level of 5.0 ng/m L was decided for survival analysis.Elevated plasma levels of cathepsin L were found to be associated with poor prognosis(P=0.01)in multivariate analysis.The plasma levels of the protease decreased after surgery.Though no significant correlation was seen between plasma and tissue expression of this protease,a trend did emerge that high cathepsin L expression in tissue correlated with its high levels in plasma.CONCLUSION:Cathepsin L levels in plasma of pancreatic cancer patients may be used as a potential prognostic marker for the disease. | Nidhi Singh Prasenjit Das Surabhi Gupta Vikas Sachdev Siddhartha Srivasatava Siddhartha Datta Gupta Ravindra Mohan Pandey Peush Sahni Shyam S Chauhan Anoop Saraya | 2014 | World Journal of Gastroenterology2014，20，46： | 2 |
| 4 | Metastatic recurrence to a solitary lymph node four years after hepatic lobectomy for primary hepatocellular carcinoma显示文摘This report describes a patient that developed recurrent metastatic hepatocellular carcinoma(HCC) to a suprapancreatic lymph node four years after being treated for primary HCC via complete left hepatectomy. Metastatic HCC was proven by pathologic confirmation. The report addresses the role of surgical resection as a treatment modality for recurrent HCC to solitary lymph nodes. The role of biological chemotherapy as adjuvant treatment is also addressed. | Michael L Caparelli Nathan J Roberts Timothy S Braverman Robert M Stevens Edward R Broun Shyam Allamaneni | 2016 | World Journal of Hepatology2016，8，23： | 2 |
| 5 | Robotic partial nephrectomy: the real benefit显示文摘 | Craig Rogers Shyam Sukumar Inderbir S Gill | 2011 | Current Opinion in Urology2011，，1： | 2 |
| 6 | The removal of heavy metals from aqueous solutions by sawdust adsorption — removal of lead and comparison of its adsorption with copper显示文摘 | Bin Yu Y Zhang Alka Shukla Shyam S Shukla Kenneth L Dorris | 2001 | Journal of Hazardous Materials2001，，1： | 2 |
| 7 | Testing static tradeoff against pecking order models of capital struc- ture显示文摘 | SHYAM -SUNDER L MYERS S C | 1999 | Journal of Financial and Economics1999，51，2： | 1 |
| 8 | Jarosite characteristics and its utilization potentials显示文摘 | ASOKAN P MOHINI S SHYAM A | 2006 | Science of the Total Environment2006，359，2： | 1 |
| 9 | Development and testing of a novel joint wear simulator and investigation of the viability of an elastomeric polyurethane for total-joint arthroplasty devices显示文摘 | Christian J S Shyam B | 2007 | Wear2007，262，： | 1 |
| 10 | Ameliorative effect of Koflet formulations against pyridine-induced pharyngitis in rats 显示文摘 | Viswanatha C L Rafiq M Thippeswamy A H M Yuvaraj H C Kavya K J Mirza R B Suryakant A Mohammed A Patki P S Pushpalatha H B Prafulla S C Shyam R | 2014 | Toxicology Reports2014，1，： | 1 |
| 11 | S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells显示文摘 | Ray S Shyam S Fraizer GC | 2007 | Mol Cancer Ther2007，6，4： | 1 |
| 12 | Diffraction method measures refractive indices of liquids显示文摘 | SHYAM S | 2004 | Physics Education2004，，3： | 1 |
| 13 | Measuring the refractive index of a liquid using a laser显示文摘 | SHYAM S | 2002 | Physics Education2002，，3： | 1 |
| 14 | Amnesia due to fornix infarction显示文摘 | Shyam S Moudgil Mouhannad Azzouz | 2000 | Stroke2000，31，： | 1 |
| 15 | An artificial neural network for non-interative calculate of the friction factor in pipe- line flow 显示文摘 | WALID H S SHYAM S S | 1998 | Computer and Electronics in Agriculture1998，21，： | 1 |
| 16 | Ginkgolide B preferentially blocks chloride channels formed by heteromeric glycine receptors in hippocampal pyramidal neurons of rat显示文摘 | Elena L Kondratskaya Alexander I Fisyunov Shyam S Chattajee | 2004 | Brain Research Bulletin2004，63，： | 1 |
| 17 | Crataegus special extract WSR 1442 improves cardiac function and reduces infarct size in a rat model of prolonged coronary ischemia and reperfusion显示文摘 | Maris V Egon K Shyam S C | 2004 | Life Sciences2004，74，： | 1 |
| 18 | Adult presentation of congenital muscular torticollis:a series of 12 patients treated with a bipolar release of sternocleidomastoid and Z-lengthening显示文摘 | Patwardhan S Shyam AK Sancheti P | | 0，，06： | 1 |
| 19 | On SIP Session Setup Delay for VolP Services Over Correlated Fading Channels 显示文摘 | Hanane Fathi Shyam S Chakraborty Ramjee Prasad | | Vehicular Technology IEEE Transactions on Volume: 55 Issue: 10，，： | 1 |
| 20 | Testing static tradeoff against pecking order models of capital structure 1显示文摘 | SHYAM S L MYERS S C | 1999 | Journal ofFinancial Economics1999，51，51： | 1 |
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