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| 1 | Indications and surgical options for small bowel, large bowel and perianal Crohn's disease显示文摘Despite advancements in medical therapy of Crohn's disease(CD), majority of patients with CD will eventually require surgical intervention, with at least a third of patients requiring multiple surgeries. It is important to understand the role and timing of surgery, with the goals of therapy to reduce the need for surgery without increasing the odds of emergency surgery and its associated morbidity, as well as to limit surgical recurrence and avoid intestinal failure. The profile of CD patients requiring surgical intervention has changed over the decades with improvements in medical therapy with immunomodulators and biological agents. The most common indication for surgery is obstruction from stricturing disease, followed by abscesses and fistulae. The risk of gastrointestinal bleeding in CD is high but the likelihood of needing surgery for bleeding is low. Most major gastrointestinal bleeding episodes resolve spontaneously, albeit the risk of re-bleeding is high. The risk of colorectal cancer associated with CD is low. While current surgical guidelines recommend a total proctocolectomy for colorectal cancer associated with CD, subtotal colectomy or segmental colectomy with endoscopic surveillance may be a reasonable option. Approximately 20%-40% of CD patients will need perianal surgery during their lifetime. This review assesses the practice parameters and guidelines in the surgical management of CD, with a focus on the indications for surgery in CD(and when not to operate), and a critical evaluation of the timing and surgical options available to improve outcomes and reduce recurrence rates. | James WT Toh Peter Stewart Matthew JFX Rickard Rupert Leong Nelson Wang Christopher J Young | 2016 | World Journal of Gastroenterology2016，22，40： | 2 |
| 2 | Texture analysis in non-contrast enhanced CT: Impact of malignancy on texture in apparently disease-free areas of the liver显示文摘 | Balaji Ganeshan Kenneth A Miles Rupert C D Young | 2009 | Eur J Radiol2009，70，： | 1 |
| 3 | Performance comparison of a linear parametric noise estimation wiener filter and non - linear joint transform correlator for realistic clutter backgrounds显示文摘 | Sovira Tan Rupert C D Young | 2000 | Opt com- mun2000，182，1： | 1 |
| 4 | A comparison of the iterative Fourier transform method and evolutionary algorithms for the design of diffractive optical elements显示文摘 | Rupert Young Maria Farsari | 2000 | Optics and Lasers in engineering2000，33，： | 1 |
| 5 | Texture analysis in non-contrast enhanced CT: Impact of malignancy on texture in apparently disease-free areas of the liver显示文摘 | Balaji Ganeshan Kenneth A Miles Rupert C D Young | 2009 | European Journal of Radiology2009，70，： | 1 |
| 6 | Texture analysis in non-contrast enhanced CT: Impact of malignancy on texture in apparently disease-free areas of the liver显示文摘 | Balaji Ganeshan Kenneth A Miles Rupert C D Young | 2009 | Eur J Radiol2009，70，： | 1 |
| 7 | On shadow elimination after moving region segmentation based on different threshold selection strategies显示文摘 | Bhargav Kumar Mitra Rupert Young Chris Chatwin | 2007 | Optics and Lasers in Engineering2007，45，： | 1 |
| 8 | Biometric iris recognition system using a fast and robust iris localization and alignment procedure显示文摘 | Ganeshan Balaji Theckedath Dhananjay Young Rupert Chatwin Chris | 2006 | Optics and Lasers in Engineering2006，44，1： | 1 |
| 9 | No-reference image quality assessment based on AdaBoost_BP neural network in wavelet domain显示文摘Considering the relatively poor robustness of quality scores for different types of distortion and the lack of mechanism for determining distortion types, a no-reference image quality assessment(NR-IQA) method based on the Ada Boost BP neural network in the wavelet domain(WABNN) is proposed. A 36-dimensional image feature vector is constructed by extracting natural scene statistics(NSS) features and local information entropy features of the distorted image wavelet sub-band coefficients in three scales. The ABNN classifier is obtained by learning the relationship between image features and distortion types. The ABNN scorer is obtained by learning the relationship between image features and image quality scores. A series of contrast experiments are carried out in the laboratory of image and video engineering(LIVE) database and TID2013 database. Experimental results show the high accuracy of the distinguishing distortion type, the high consistency with subjective scores and the high robustness of the method for distorted images. Experiment results also show the independence of the database and the relatively high operation efficiency of this method. | YAN Junhua BAI Xuehan ZHANG Wanyi XIAO Yongqi CHATWIN Chris YOUNG Rupert BIRCH Phil | 2019 | Journal of Systems Engineering and Electronics2019，30，2： | 1 |
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