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    题名 作者 年代 出处 被引量
1Sustainable H2 production from ethanol steam reforming over a macro-mesoporous Ni/Mg-Al-O catalytic monolith显示文摘macro-meso-porous 整体的基于 Ni 的催化剂作为模板用聚苯乙烯泡沫经由一条受精线路被准备然后在乙醇改过生产 H2 富有的气体的蒸气使用了。Ni/Mg-Al 催化剂有一层次地由相片和扫描电子显微镜学(SEM ) 显示了的 macro-meso-porous 结构。催化剂的表面区域是 230Ruixue GU Guangming ZENG Jingjing SHAO Yuan LIU Johannes W. Schwank Yongdan LI 2013Frontiers of Chemical Science and Engineering2013,7,3:2
2Strontium-incorporated bioceramic scaffolds for enhanced osteoporosis bone regeneration显示文摘The restoration of bone defects caused by osteoporosis remains a challenge for surgeons.Strontium ranelate has been applied in preventative treatment approaches due to the biological functions of the trace element strontium(Sr).In this study,we aimed to fabricate bioactive scaffolds through Sr incorporation based on our previously developed modified amino-functional mesoporous bioactive glass(MBG)and to systematically investigate the bioactivity of the resulting scaffold in vitro and in vivo in an osteoporotic rat model.The results suggested that Sr-incorporated amino-functional MBG scaffolds possessed favorable biocompatibility.Moreover,with the incorporation of Sr,osteogenic and angiogenic capacities were upregulated in vitro.The in vivo results showed that the Sr-incorporated amino-functional MBG scaffolds achieved better bone regeneration and vessel formation.Furthermore,bioinformatics analysis indicated that the Sr-incorporated amino-functional MBG scaffolds could reduce reactive oxygen species levels in bone marrow mesenchymal stem cells in the osteoporotic model by activating the cAMP/PKA signaling pathway,thus playing an anti-osteoporosis role while promoting osteogenesis.This study demonstrated the feasibility of incorporating trace elements into scaffolds and provided new insights into biomaterial design for facilitating bone regeneration in the treatment of osteoporosis.Qianju Wu Longwei Hu Ran Yan Junfeng Shi Hao Gu Yuwei Deng Ruixue Jiang Jin Wen Xinquan Jiang 2022Bone Research2022,10,4:1
3Synergy effeci of MgO and ZnO in a Ni/Mg-Zn-Al catalyst during ethanol steam reforming for H2-rich gas production显示文摘Zeng Guangming Liu Qinghua Gu Ruixue 2011Catalysis Today2011,178,1:1
4Development of an LC–MS/MS method for the quantitation of deoxyglycychloxazol in rat plasma and its application in pharmacokinetic study显示文摘Deoxyglycychloxazol(TY501) is a glycyrrhetinic acid derivative which exhibits high anti-inflammatory activity and reduced pseudoaldosteronism compared to glycyrrhetinic acid.In this study,a sensitive and rapid liquid chromatography–tandem mass spectrometry(LC–MS/MS) method was established for the quantitation of TY501 in rat plasma.Plasma samples were treated by precipitating protein with methanol and supernatants were separated by a Symmetry C_8 column with the mobile phase consisting of methanol and 10 m M ammonium formate(containing 0.1% of formic acid)(90:10,v/v).The selected reaction monitoring(SRM) transitions were performed at m/z 647.4-191.2 for TY501 and m/z 473.3-143.3 for astragaloside aglycone(IS) in the positive ion mode with atmospheric pressure chemical ionization(APCI) source.Calibration curve was linear over the concentration range of 5–5000 ng/m L.The lower limit of quantification was 5 ng/m L.The mean recovery was over 88%.The intra- and inter-day precisions were lower than 6.0% and 12.8%,respectively,and the accuracy was within 7 1.3%.TY501 was stable under usual storage conditions and handling procedure.The validated method has been successfully applied to a pharmacokinetic study after oral administration of TY501 to rats at a dosage of 10 mg/kg.Rongshan Li Ruixue Ran Quansheng Li Yurong Huang Yuan Gu Duanyun Si 2016Journal of Pharmaceutical Analysis2016,6,3:0
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