| 3 | Multidisciplinary team for the diagnosis and treatment of 2cases of primary intestinal yolk sac tumor显示文摘Extragonadal primary yolk sac tumor of the intestinal tract origin is exceedingly rare. Through a multiple disciplinary team, the diagnosis and treatment of primary intestinal yolk sac tumor were further defined. We report 2 such cases with detailed histologic and immunohistochemical analysis. The two patients were a 7-year-old girl and a 29-year-old woman. Both of them preoperatively had an elevated serum alpha fetoprotein(AFP) level(≥ 1,210 ng/mL). The tumors are located in the intestine and imaging examination indicated the rectum as the primary site. Grossly the mass was grey-white and crisp texture. Microscopic examination featured reticular, microcystic, macrocystic, papillary, solid, and some glandular patterns. Immunohistochemically,tumor cells of both cases were positive for SALL4, AFP, pan-cytokeratin(AE1/AE3), and glypican-3. Simultaneously, a stain for EMA, OCT4, CD30, HCG, vimentin and CK20 were negative in all 2 neoplasms. The features of morphology,immunohistochemistry, laboratory examinations and imaging studies consist of the diagnosis of primary yolk sac tumor of the intestine. | Qiujuan Huang Changxu Liu Ruijun Tang Jie Li Wei Li Lei Zhu Yuhong Guo Lin Zhang Tongyuan Qu Lingyi Yang Lingmei Li Yalei Wang Baocun Sun Bin Meng Jie Yan Wengui Xu Huilai Zhang Dengfeng Cao Wenfeng Cao | 2018 | Cancer Biology & Medicine2018，15，4： | 0 |
| 4 | Preventive behaviours and family inequalities during the COVID-19 pandemic:a cross-sectional study in China显示文摘Background The coronavirus disease 2019(COVID-19)pandemic is an international public health threat,and people's participation in disease-related preventive behaviours is the key to controlling infectious diseases.This study aimed to assess the differences in adopting preventive behaviours among populations to explore potential individual and household factors and inequalities within families.Methods This online survey was conducted in April 2020.The directional stratified convenient sampling method was used to select 4704 participants from eight provinces in eastern,central,and western China.The questionnaire included demographic information,household variables,and five target prevention behaviours.The chi-squared test,binary multilevel model,and Mantel–Haenszel hierarchical analysis were used for data analysis in the study.Results Approximately 71.2%of the participants had appropriate outdoor prevention,and 32.9%of the participants had indoor protection in place.Sharing behaviours(P<0.001)and education level(P<0.001)were positively associated with adopting preventive measures.The inhibiting effect of household crowding and stimulating effect of high household income on preventive behaviours were determined in this study.Household size was negatively associated with living area(β=-0.057,P<0.05)and living style(β=-0.077,P<0.05).Household income was positively associated with age(β=0.023,P<0.05),and relationship with friends(β=0.053,P<0.05).Vulnerable groups,such as older adults or women,are more likely to have inadequate preventive behaviours.Older adults(OR=1.53,95%CI 1.09–2.15),women(OR=1.37,95%CI 1.15–1.64),and those with more than 2 suspected symptoms(OR=1.85,95%CI 1.07–3.19)were more likely to be affected by the inhibiting effect of household crowding,while the stimulating effect of high household income was limited in these groups.Conclusions Inequalities in COVID-19 prevention behaviours exist between families and inadequate adoption of prevention by vulnerable groups are noteworthy.This study expands the research perspective by emphasizing the role of household factors in preventive behaviours and by focusing on family inequalities.The government should use traditional media as a platform to enhance residents’public health knowledge.Targeted additional wage subsidies,investments in affordable housing,financial support for multigenerational households,and temporary relocation policies may deserve more attention.Communities could play a critical role in COVID-19 prevention. | Yisheng Ye Ruijun Wu Yao Ge Tao Wang Xin Yao Yao Yang Chengxu Long Fangfei Chen Shangfeng Tang Rui Huang | 2021 | Infectious Diseases of Poverty2021，10，4： | 0 |
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