|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Challenges of 22 nm and beyond CMOS technology显示文摘It is predicted that CMOS technology will probably enter into 22 nm node around 2012. Scaling of CMOS logic technology from 32 to 22 nm node meets more critical issues and needs some significant changes of the technology, as well as integration of the advanced processes. This paper will review the key processing technologies which can be potentially integrated into 22 nm and beyond technology nodes, including double patterning technology with high NA water immersion lithography and EUV lithography, new device architectures, high K/metal gate (HK/MG) stack and integration technology, mobility enhancement technologies, source/drain engineering and advanced copper interconnect technology with ultra-low-k process. | HUANG Ru WU HanMing KANG JinFeng XIAO DeYuan SHI XueLong AN Xia TIAN Yu WANG RunSheng ZHANG LiangLiang ZHANG Xing WANG YangYuan | 2009 | Science in China(Series F)2009，52，9： | 8 |
| 2 | Incidence of pocket hematoma after electrophysiological device placement:dual antiplatelet therapy versus low-molecular-weight heparin regimen显示文摘BackgroundGiven 要求双 antiplatelet 的病人的增加的数字(弹跳) 治疗和 electrophysiological 设备(EPD ) 放置, perioperative antiplatelet 管理是当前的挑战。在这研究,我们在经历的病人在 EPD 放置以后调查了袖珍 hematoma 形成的发生弹跳治疗或其他的 low-molecular-weight 肝磷脂(LMWH ) regimen.MethodsThis 临床的观察学习从 2010 年 7 月被执行到 2012 年 7 月。总共, 171 个病人在满足包括标准以后在分析被注册。这些病人被划分成二个组:86 个病人被对待与弹跳治疗在设备培植,和 DAP 治疗的时候被中止 5 ~ 7 天并且在另外的 85 个病人在设备培植前用 enoxaparin 代替了。腺苷磷酸盐(自动数据处理) 调停了血小板聚集和 arachidonic 导致酸的血小板聚集外科手术前地被测试。我们把在二个组和袖珍 hematoma 开发的协会之间的袖珍 hematoma 的发生与调停自动数据处理的血小板聚集和 arachidonic 作比较在继续的病人的袖珍 hematoma 的导致酸的血小板 aggregation.ResultsThe 发生弹跳在用 LMWH 代替了双 antiplatelet 政体的病人是比那低的(3.49%对16.47%分别地;X 2= 6.66, P <0.01 ) 。在继续的病人之中弹跳治疗,没有袖珍 hematomas,在有袖珍 hematomas 的病人的调停自动数据处理的血小板聚集抑制的率在病人比那高。没有经历的病人弹跳或 enoxaparin 治疗得了袖珍感染, thromboembolic 事件,或另外的严肃的复杂并发症。多重逻辑回归分析表明那 LMWH 治疗是为袖珍 hematoma 的发展的一个独立风险因素(RR = 0.054, 95%CI = 0.012-0.251 ) 。而且,经历 LMWH 治疗的病人比是弹跳对待 individuals.ConclusionContinuance 的多半更是 5.1 褶层开发袖珍 hematomas 弹跳治疗不在 EPD 以后增加袖珍 hematoma 形成的风险放置。 | Yan CHEN Yun-Tao LI Ming-Dong GAO Ze-Chun ZENG Jin-Rong ZHANG Hong-Liang CONG Yin LIU Ru ZHAO Le-Feng WANG Xin-Cun YANG Kang MENG | 2014 | Journal of Geriatric Cardiology2014，11，3： | 3 |
| 3 | PVP-Supported Palladium-Cadmium Bimetallic Catalyst for the Hydrogen Transfer Dechlorination of Aryl Chlorides显示文摘PVP-supported bimetallic catalyst- PVP-PdCl2-CdCl2, exhibits extremely high catalytic activity for the hydrogen transfer dechlorination of aryl chlorides in neutral environment. The yields of dechlorination products are high under mild reaction conditions and the operation is | Ru Hong KANG Jiang Hua MA Xin Hui LIU Shu Mei HE(Chemistry Department of Flebei Normal University. Shijiazhuang 050016)(Experimental Center of Hebei Normal University. Shijiazhuang 050016) | 1999 | Chinese Chemical Letters1999，10，7： | 3 |
| 4 | Effect of co-existent components in CO2 supercritical fluid extract of Angelica Sinensis Radix on metabolism of Z-ligustilide after oral administration in rats显示文摘Objective:To establish a basis for Angelica Sinensis Radix(ASR)as a dietary supplement for colorectal cancer chemoprevention,the effect of co-existent components in supercritical fluid extract(SFE)of ASR on the pharmacokinetics of Z-ligustilide after oral administration was investigated in vitro and in vivo.Methods:Incubation in gastrointestinal contents and incubation in rat liver tissue homogenates post-mitochondrial supernatant(PMS)experiments were used to study changes in the levels of Z-ligustilide in vitro.Results:Within 4 hours,the level of Z-ligustilide in SFE declined at a slower rate than in its pure form.Clearance of Z-ligustilide after administration in its pure form was significantly slower than that of SFE of ASR(CL,0.96±0.16 mL·min/kg versus 1.24±0.21 mL·min/kg P<0.05;AUC,243.37±16.84 versus 176.69±12.59 mg·min/L).Conclusion:These phenomena may be attributed to the interactions between the co-existent components in SFE of ASR and Z-ligustilide enhancing the stability of Z-ligustilide.These results suggest that the bioavailability of Z-ligustilide in SFE of ASR is improved.However,stabilization of plasma concentration was not sustained,so that the efficacy of active components could not be maintained.Thus,further processing of SFE of ASR is required. | Bochen Zhao Qing Zhang Hongmei Lin Qingguo Ru Qian Kang Hui Li Yewen Zhang Qing Wu | 2014 | Journal of Traditional Chinese Medical Sciences2014，1，2： | 2 |
| 5 | Measurement of vibratory motions of gears supported by compliant shafts 显示文摘 | Ma Ru Kang Ahmet Kahraman | 2012 | Mechanical Systems and SignalProeessing(S0094-114X)2012，29，： | 1 |
| 6 | Design and Dynamic Locomotion Control of Quadruped Robot with Perception-Less Terrain Adaptation显示文摘In this paper,a parallel quadrupedal robot was designed that is capable of versatile dynamic locomotion and perception-less terrain adaptation.Firstly,a quadrupedal robot with a symmetric legs and a powerful actuator was implemented for highly dynamic movement.Then,a fast and reliable method based on generalized least square was proposed for estimating the terrain parameters by fusing the body,leg,and contact information.On the basis of virtual model control(VMC)with the quadratic program(QP)method,the optimal foot force for terrain adaptation was achieved.Finally,the results obtained by simulation and indoor and outdoor experiments demonstrate that the robot can achieve a robust and versa tile dynamic locomotion on uneven terrain,and the rejection of disturbances is reliable,which proves the effectiveness and robustness of this proposed method. | Lei Wang Libo Meng Ru Kang Botao Liu Sai Gu Zhihao Zhang Fei Meng Aiguo Ming | 2022 | Cyborg and Bionic Systems2022，，1： | 1 |
| 7 | Attapulgite/ bentonite interactions for methylene blue adsorption characteristics from aqueous solution显示文摘 | YI LIU YU RU KANG BIN MU | 2014 | Chemical Engineering Journal2014，，237： | 1 |
| 8 | Osteoprotective effect of combination therapy of low-dose oestradiol with G15,a specific antagonist of GPR30/GPER in ovariectomyinduced osteoporotic rats显示文摘 | Kang WB Cong Y Ru JY | 2015 | Biosci Rep2015，35，00： | 1 |
| 9 | Novel Phosphonoacetic Acid Derivatives.Synthesis of N-(Ethoxycarbonylmethylphosphonyl)-α-Amino Esters and-α-Amino Phosphonic Acid Esters and Their Bioactivities显示文摘A series of novel phosphonoacetic acid derivatives, N-(ethoxycarbonylmethy-ethoxyphosphonyl)-α-amino acid esters and α-amino phosphonates, were synthesized via the reaction of the corresponding phosphonyl chloride with amino acid ester hydrochlorides or amino phosphonates in the presence of a base. The preliminary bioassay shows that some compounds show significant anti-viral activity against tobacco mosaic virus (TMV) | Hui Ying LI Kang Tai REN Ru Yu CHEN(Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071) | 1997 | Chinese Chemical Letters1997，8，12： | 0 |
| 10 | QUANTUM CHEMICAL CALCULATIONS ON THE ELECTRONIC STRUCTURE AND SPECTRA OF[Mo_3O_4-nSn]^(4+)(n=O-4)CLUSTER CATIONS显示文摘The electronic structure and spectra of [Mo3O4-nSn]4+(n=0-4)cations were calculated by means of INDO/CI quantum chemistry method toaccount for the experimental data of their spectra in water solutions. | Zhi Ru LI Qian Shu LI Ji Kang FANG Zhi Ren ZHENG Jun ZHENG Department of Chemistry,Jilin University,Changchun,130023 | 1992 | Chinese Chemical Letters1992，3，1： | 0 |
| 11 | Correlation between Nrf2‑GPX4 signaling pathway and patients with coronary heart disease显示文摘Objective:To analyze the correlation between serum Nrf2 and GPX4 activity levels with coronary heart disease(CHD)and the severity of coronary artery disease,and to explore the role of ferroptosis mediated by its signaling pathway in the progression of CHD.Methods:A total of 540 patients suspected of CHD were selected for coronary angiography,of which 360 patients were diagnosed with CHD.The activity levels of Nrf2 and GPX4 in the serum of CHD patients were detected by ELISA,and the differences in the activities of Nrf2 and GPX4 in the presence or absence of CHD were statistically analyzed.Western blot detection of Nrf2 protein expression of peripheral blood mononuclear cells(PBMCS)in the control(CON)and CHD groups(90 cases each).The expression and significance of its signaling pathway in CHD patients were analyzed.Results:The activity levels of Nrf2 and GPX4 in the CHD group were lower than those in the CON group(P<0.05),and the expression levels of Nrf2 in PBMCs of the two groups were detected by Western blot.The protein expression level of Nrf2 in the CHD group(0.25±0.05)was down‑regulated compared with CON group(0.87±0.16)(P<0.05),indicating that Nrf2 protein expression level was low in CHD patients.Pearson correlation analysis showed that serum Nrf2 and GPX4 levels were negatively correlated with Gensini score(Nrf2:r=‑0.347,P<0.001;GPX4:r=-0.423,P=0.001).Nrf2 and GPX4 were negatively correlated with TG(Nrf2:r=-0.284,P<0.001;GPX4:r=-0.275,P=0.001),Nrf2 and GPX4 levels were negatively correlated with LDL(Nrf2:r=-0.418,P<0.001)0.05;(GPX4:r=-0.426,P<0.05),Nrf2 and GPX4 levels were positively correlated with HDL(Nrf2:r=0.318,P<0.05;GPX4:r=0.428,P<0.05),and Nrf2 was positively correlated with GPX4(r=0.456,P<0.01).Conclusion:The ferroptosis pathway mediated by the Nrf2‑GPX4 signaling pathway is closely related to the degree of coronary artery disease and the pathogenesis of CHD,and its mechanism may be related to the down‑regulation of the Nrf2‑GPX4 signaling pathway. | XING Bu‑dian LI Hui QIANG Tian‑tian WEI Ting LU Yuan‑yuan KANG Pin‑fang ZHANG Ning‑ru | 2023 | Journal of Hainan Medical University2023，29，12： | 0 |
| 12 | DNA methylation markers in the diagnosis and prognosis of common leukemias显示文摘The ability to identify a specific type of leukemia using minimally invasive biopsies holds great promise to improve the diagnosis,treatment selection,and prognosis prediction of patients.Using genome-wide methylation profiling and machine learning methods,we investigated the utility of CpG methylation status to differentiate blood from patients with acute lymphocytic leukemia(ALL)or acute myelogenous leukemia(AML)from normal blood.We established a CpG methylation panel that can distinguish ALL and AML blood from normal blood as well as ALL blood from AML blood with high sensitivity and specificity.We then developed a methylation-based survival classifier with 23 CpGs for ALL and 20 CpGs for AML that could successfully divide patients into high-risk and low-risk groups,with significant differences in clinical outcome in each leukemia type.Together,these findings demonstrate that methylation profiles can be highly sensitive and specific in the accurate diagnosis of ALL and AML,with implications for the prediction of prognosis and treatment selection. | Hua Jiang Zhiying Ou Yingyi He Meixing Yu Shaoqing Wu Gen Li Jie Zhu Ru Zhang Jiayi Wang Lianghong Zheng Xiaohong Zhang Wenge Hao Liya He Xiaoqiong Gu Qingli Quan Edward Zhang Huiyan Luo Wei Wei Zhihuan Li Guangxi Zang Charlotte Zhang Tina Poon Daniel Zhang Ian Ziyar Run-ze Zhang Oulan Li Linhai Cheng Taylor Shimizu Xinping Cui Jian-kang Zhu Xin Sun Kang Zhang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 0 |
| 13 | SYNTHESIS OF DIARYL ETHERS THROUGH PHASE TRANSFER CATALYSIS WITH POTASSIUN FLUORIDE COATED ALUMINA AS A STRONG BASE显示文摘Seven diaryl ethers were synthesized with potassium fluoridecoated alumina as a strong base and the addition of catalytic amount of PTC.The yield of diaryl ethers with addition of PTC was much higher than thatwithout PTC.A discussion of the catalysis mechanism was given in this paper. | Ru Hong KANG Ji Sheng ZHU Wen Zi LI Shu Rong LIU Department of Chemistry,Hebei Normal University,Shijiazhuang | 1990 | Chinese Chemical Letters1990，1，1： | 0 |
| 14 | SYNTHESIS AND CATALYSTIC BEHAVIOR OF A HEW PHASE-TRANSFER CATALYST SUPPORTEI) OB SILICA GEL显示文摘A new catalyst with quaternary ammonium cation activated polyether chains immobilized on silica gel was applied to promote the reations of KI with n-C4H9-Br and KSCH with n-C4H9Br. The new catalyst showed much significant activity over other PEG functionalized silica gel. | Ru Hong KANG~*, Jian Lu ZHAO, Hui Lan CHEN Wen Juan QIE, Wei Zhan JI Chemistry Department Of Hebei Normal University Shi. jiazhuang Hebei 050016 | 1993 | Chinese Chemical Letters1993，4，1： | 0 |
| 15 | Fire Risks and Prevention Strategies for Architecture at Historic Sites显示文摘This paper mainly discusses the features of China’s architecture at historic sites with regard to fire protection, the causes of fire since 1949, reviewing their weaknesses in fire protection, and exploring modern technologies for fire prevention that are applicable to ancient buildings. We put forward suggestions to improve fire prevention and management: eliminating potential problems of fire, improving fire protection and establishing a better fire security system, which is especially important to protect ancient buildings. | | 2006 | China Standardization2006，51，3： | 0 |
| 16 | A compact multi-pixel superconducting nanowire single-photon detector array supporting gigabit space-to-ground communications显示文摘Classical and quantum space-to-ground communications necessitate highly sensitive receivers capable of extracting information from modulated photons to extend the communication distance from near-earth orbits to deep space explorations.To achieve gigabit data rates while mitigating strong background noise photons and beam drift in a highly attenuated free-space channel,a comprehensive design of a multi-functional detector is indispensable.In this study,we present an innovative compact multi-pixel superconducting nanowire single-photon detector array that integrates near-unity detection efficiency(91.6%),high photon counting rate(1.61 Gcps),large dynamic range for resolving different photon numbers(1-24),and four-quadrant position sensing function all within one device.Furthermore,we have constructed a communication testbed to validate the advantages offered by such an architecture.Through 8-PPM(pulse position modulation)format communication experiments,we have achieved an impressive maximum data rate of 1.5 Gbps,demonstrating sensitivities surpassing previous benchmarks at respective speeds.By incorporating photon number information into error correction codes,the receiver can tolerate maximum background noise levels equivalent to 0.8 photons/slot at a data rate of 120 Mbps—showcasing a great potential for daylight operation scenarios.Additionally,preliminary beam tracking tests were conducted through open-loop scanning techniques,which revealed clear quantitative dependence indicating sensitivity variations based on beam location.Based on the device characterizations and communication results,we anticipate that this device architecture,along with its corresponding signal processing and coding techniques,will be applicable in future space-to-ground communication tasks. | Hao Hao Qing-Yuan Zhao Yang-Hui Huang Jie Deng Fan Yang Sai-Ying Ru Zhen Liu Chao Wan Hao Liu Zhi-Jian Li Hua-Bing Wang Xue-Cou Tu La-Bao Zhang Xiao-Qing Jia Xing-Long Wu Jian Chen Lin Kang Pei-Heng Wu | 2024 | Light(Science & Applications)2024，13，2： | 0 |
| 17 | Research progress of TCM regulating mTOR signaling pathway in the treatment of Alzheimer's disease显示文摘Alzheimer's disease(AD)is a degenerative disease of the central nervous system.The pathogenesis of AD is complex and diverse,and its occurrence and development is the result of the interaction of multiple factors.A number of studies have shown that mTOR signaling pathway is closely related to AD.In recent years,people in exploring relevant methods for the treatment of AD and the process of drugs,more and more studies have found that traditional Chinese medicine compound traditional Chinese medicine monomer,and can be applied to mTOR signaling pathway to improve symptoms in patients with AD.This paper will review the mechanism of action and treatment of TCM in Alzheimer's disease based on mTOR signaling pathway in recent years,so as to provide reference and expand thinking for the prevention and treatment of AD. | LIU Chang‑ning ZHANG Li‑juan HOU Han‑ru GUAN Xiu‑ju ZHU Ling‑hui WANG Kang‑feng | 2023 | Journal of Hainan Medical University2023，29，8： | 0 |
| 18 | Genome resources for the elite bread wheat cultivar Aikang 58 and mining of elite homeologous haplotypes for accelerating wheat improvement显示文摘Despite recent progress in crop genomics studies,the genomic changes brought about by modern breeding selection are still poorly understood,thus hampering genomics-assisted breeding,especially in polyploid crops with compound genomes such as common wheat(Triticum aestivum).In this work,we constructed genome resources for the modern elite common wheat variety Aikang 58(AK58).Comparative genomics between AK58 and the landrace cultivar Chinese Spring(CS)shed light on genomic changes that occurred through recent varietal improvement.We also explored subgenome diploidization and divergence in common wheat and developed a homoeologous locus-based genome-wide association study(HGWAS)approach,which was more effective than single homoeolog-based GWAS in unraveling agronomic trait-associated loci.A total of 123 major HGWAs loci were detected using a genetic population derived from AK58 and cs.Elite homoeologous haplotypes(HHs),formed by combinations of subgenomic homoeologs of the associated loci,were found in both parents and progeny,and many could substantially improve wheat yield and related traits.We built a website where users can download genome assembly sequence and annotation data for AK58,perform blast analysis,and run JBrowse.Our work enriches genome resources for wheat,provides new insights into genomic changes during modern wheat improve-.ment,and suggests that efficientmining of elite HHs can make a substantial contribuutionto genomics-assisted breeding in common wheat and other polyploid crops. | Jizeng Jia Guangyao Zhao Danping Li Kai Wang Chuizheng Kong Pingchuan Deng Xueqing Yan Xueyong Zhang Zefu Lu Shujuan Xu Yuannian Jiao Kang Chong Xu Liu Dangqun Cui Guangwei Li Yijing Zhang Chunguang Du Liang Wu Tianbao Li Dong Yan Kehui Zhan Feng Chen Zhiyong Wang Lichao Zhang Xiuying Kong Zhengang Ru Daowen Wang Lifeng Gao | 2023 | Molecular Plant2023，16，12： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员