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| 1 | Infectious, atopic and inflammatory diseases, childhood adversities and familial aggregation are independently associated with the risk for mental disorders: Results from a large Swiss epidemiological study显示文摘AIM To examine the associations between mental disorders and infectious, atopic, inflammatory diseases while adjusting for other risk factors.METHODS We used data from PsyC oL aus, a large Swiss Population Cohort Study(n = 3720; age range 35-66). Lifetime diagnoses of mental disorders were grouped into the following categories: Neurodevelopmental, anxiety(early and late onset), mood and substance disorders. They were regressed on infectious, atopic and other inflammatory diseases adjusting for sex, educational level, familial aggregation, childhood adversities and traumatic experiences in childhood. A multivariate logistic regression was applied to each group of disorders. In a complementary analysis interactions with sex were introduced via nested effects. RESULTS Associations with infectious, atopic and other chronic inflammatory diseases were observable together with consistent effects of childhood adversities and familial aggregation, and less consistent effects of trauma in each group of mental disorders. Streptococcal infections were associated with neurodevelopmental disorders(men), and measles/mumps/rubella-infections with early and late anxiety disorders(women). Gastric inflammatory diseases took effect in mood disorders(both sexes) and in early disorders(men). Similarly, irritable bowel syndrome was prominent in a sex-specific way in mood disorders in women, and, moreover, was associated with early and late anxiety disorders. Atopic diseases were associated with late anxiety disorders. Acne(associations with mood disorders in men) and psoriasis(associations with early anxiety disorders in men and mood disorders in women) contributed sex-specific results. Urinary tract infections were associated with mood disorders and, in addition, in a sex-specific way with late anxiety disorders(men), and neurodevelopmental and early anxiety disorders(women).CONCLUSION Infectious, atopic and inflammatory diseases areimportant risk factors for all groups of mental disorders. The sexual dimorphism of the associations is pronounced. | Vladeta Ajdacic-Gross Aleksandra Aleksandrowicz Stephanie Rodgers Margot Mutsch Anja Tesic Mario Müller Wolfram Kawohl Wulf R?ssler Erich Seifritz Enrique Castelao Marie-Pierre F Strippoli Caroline Vandeleur Roland von K?nel Rosa Paolicelli Markus A Landolt Cornelia Witthauer Roselind Lieb Martin Preisig | 2016 | World Journal of Psychiatry2016，6，4： | 2 |
| 2 | Improved oxidation of air pollutants in a non-thermal plasma 显示文摘 | Holzer F Kopinke F D | 2002 | Catalysis Today2002，73，34： | 1 |
| 3 | Hepatitis C virus breast milk显示文摘 | Roland Z Danielep Jean-Claude F | 1995 | The Lancet1995，345，： | 1 |
| 4 | Mechanism of kaolinite dissolution at room temperature and pressure, part Ⅱkinetic study显示文摘 | JAVIER H F LEI Chou WOLLAST Roland | 1999 | Geochimica et Cosmochimica Acta1999，63，20： | 1 |
| 5 | Improved Oxidation of Air Pollutants in a Non-thermal Plasma 显示文摘 | U Roland F Holzer F D Kopinke | 2002 | Catalysis Today2002，73，： | 1 |
| 6 | Improved oxidation of air pollutants in a non-thermal plasma 显示文摘 | ROLAND U HOLZER F KOPINKE F D | 2002 | Catalysis Today2002，73，： | 1 |
| 7 | Energy and Exports in China 显示文摘 | Kahrl F Roland - Holst D | 2008 | China Economic Review2008，19，4： | 1 |
| 8 | Advanced joining techniques in European shipbuilding显示文摘 | Roland F Manzon L | 2004 | Journal ofproduction2004，3，20： | 1 |
| 9 | Improved oxidation of air pollutants in a non-thermal plasma显示文摘 | Roland U Holzer F Kopine F | 2002 | Catalyst Today2002，73，34： | 1 |
| 10 | Nutrient-chlorophyll relationships in tropical-subtropical lakes:do temperate models fit?显示文摘 | Huszar V L M Caraco N F Roland F | 2006 | Biogeochemistry2006，79，12： | 1 |
| 11 | 查看详情显示文摘 | F Holzer U Roland FD Kopinke | | 0，，： | 1 |
| 12 | Investigation of Spray Cooling Heat Transfer for Continuous Slab Casting 显示文摘 | Ramstorfer F Roland J | 2011 | Materi- als and Manufacturing Processes2011，26，1： | 1 |
| 13 | 查看详情显示文摘 | U Roland F Holzer FD Kopinke | | 0，，： | 1 |
| 14 | Graier,Uncoupling proteins 2 and 3 are fundamental for mitoehondrial Ca2+uniport显示文摘 | Roland Malli lsmene Fertschai Sanja LevakFrank andWolfgang F | 2007 | NATURE CELL BIOLOGY2007，9，4： | 1 |
| 15 | Evaluation of an improved hybrid six-flux/zone model for radiant transfer in rectangular enclosures显示文摘 | Christian S Roland K Stefan F | 1995 | Journal of Heat and Mass Transfer1995，38，18： | 1 |
| 16 | Energy and Exports in China 显示文摘 | Kahrl F Roland H D | 2008 | China Economic Review2008，19，4： | 1 |
| 17 | Synthetic applications of epoxide hydrolases显示文摘 | Alain A Roland F | 2001 | Current ()pinion in Chemical Biology2001，5，： | 1 |
| 18 | Single - dose, extendedrelease epidural morphine(DepoDur)compared to con- ventional epidural morphine for post - cesarean pain 显示文摘 | Carvalho B Roland L M Chu L F | 2007 | Anesth Analg2007，105，1： | 1 |
| 19 | Activity of linezolid against Gram-positive coccipossessing genes conferring resi-stance to protein synthesis inhibitors显示文摘 | Marquerite F Roland L | 2000 | J AntimicrobChemother2000，45，： | 1 |
| 20 | Combina-tion of non-thermal plasma and heterogeneous catalysisfor oxidation of volatile organic compounds显示文摘 | HOLZER F ROLAND U KOPINKE F D | 2002 | Ap-plied Catalysis:B Environmental2002，38，3： | 1 |
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