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| 1 | Percutaneous closure of secundum type atrial septal defects:More than 5-year follow-up显示文摘AIM: To investigate long-term efficacy of two different devices more than five years after percutaneous atrial septal defect(ASD) closure in adults.METHODS: All patients who underwent percutaneous closure of an ASD in the St. Antonius Hospital, Nieuwegein, The Netherlands, between February 1998 and December 2006 were included. Percutaneous closure took place under general anaesthesia and transesophageal echocardiographic moni toring. Transthoracic echocardiography(TTE) was performed 24 h post-procedure to visualize the device position and to look for residual shunting using color Doppler. All complications were registered. All patients were invited for an outpatient visit and contrast TTE more than 5-years after closure. Efficacy was based on the presence of a residual right-to-left shunt(RLS), graded as minimal, moderate or severe. The presence of a residual left-to-right shunt(LRS) was diagnosed using color Doppler, and was not graded. Descriptive statistics were used for patients' characteristics. Univariate analysis was used to identify predictors for residual shunting.RESULTS: In total, 104 patients(mean age 45.5 ± 17.1 years) underwent percutaneous ASD closure using an Amplatzer device(ASO) in 76 patients and a Cardioseal/Starflex device(CS/SF) in 28 patients. The mean follow-up was 6.4 ± 3.4 years. Device migration occurred in 4 patients of whom two cases occurred during the index hospitalization(1 ASO, 1 CS/SF). The other 2 cases of device migration occurred during the first 6 mo of follow-up(2 CS/SF). The recurrent thrombo-embolic event rate was similar in both groups: 0.4% per follow-up year. More than 12 mo post-ASD closure and latest follow-up, new-onset supraventricular tachyarrhythmia's occurred in 3.9% and 0% for the ASO and CS/SF group, respectively. The RLS rate at latest follow-up was 17.4%(minimal 10.9%, moderate 2.2%, severe 4.3%) and 45.5%(minimal 27.3%, moderate 18.2%, severe 0%) for the ASO- and CS/SF groups, respectively. There was no residual LRS in both groups.CONCLUSION: Percutaneous ASD closure has good long-term safety and efficacy profiles. The residual RLS rate seems to be high more than 5 years after closure, especially in the CS/SF. Residual LRS was not observed. | Roel JR Snijder Maarten J Suttorp Jurrien M Ten Berg Martijn C Post | 2015 | World Journal of Cardiology2015，7，3： | 6 |
| 2 | Transanal total mesorectal excision: Myths and reality显示文摘Transanal total mesorectal excision(TaTME) is a new and promising approach for the treatment of rectal cancer. Whilst the experience is still limited, there are growing evidences that this approach might overcome the limits of standard low anterior resection. TaTME might help to decrease the conversion rate especially in difficult patients, and to improve the pathological results, while preserving the urogenital function. Evaluation of data from large registries and randomized studies should help to draw firmer conclusions. Beyond these technical considerations, the next challenge seems to be clearly the safe introduction of this approach, motivating the development of dedicated courses. | Nicolas C Buchs Marta Penna Alexander L Bloemendaal Roel Hompes | 2016 | World Journal of Clinical Oncology2016，7，5： | 5 |
| 3 | Transanal total mesorectal excision:a valid option for rectal cancer?显示文摘Low anterior resection can be a challenging operation, especially in obese male patients and in particular after radiotherapy. Transanal total mesorectal excision(Ta TME) might offer technical advantages over laparoscopic or open approaches particularly for tumors in the distal third of the rectum. The aim of this article is to review the current experience with Ta TME. The limits and future developments are also explored. Although the experience with Ta TME is still limited, it might be a promising alternative to laparoscopic TME, especially for difficult cases where laparoscopy is too demanding. The preliminary data on complications and short-term oncological outcomes are good, but also emphasize the importance of careful patient selection. Finally, there is a need for large-scale trials focusing on long-term outcomes and oncological safety before widespread adoption can be recommended. | Nicolas C Buchs Gary A Nicholson Frederic Ris Neil J Mortensen Roel Hompes | 2015 | World Journal of Gastroenterology2015，21，41： | 3 |
| 4 | Reliability of ma- terial data measurements for hygroscopic buffering显示文摘 | ROELS S TALUKDAR P JAMES C | 2010 | Inter- national Journal of Heat and Mass Transfer2010，53，2324： | 1 |
| 5 | The use of FDG- PET/CT and diffusion-weighted magnetic resonance imaging for response prediction before, during and after preoperative chemoradiotherapy for rectal cancer显示文摘 | Lambrecht M Deroose C Roels S | 2010 | Acta Oneol2010，49，7： | 1 |
| 6 | An XAFS study of the different influence of chelating ligands on the HDN and HDS of -A12 O3-supported NiMo catalysts显示文摘 | RICCARDO C FABIO R ROEL P | 2001 | J Catul2001，199，2： | 1 |
| 7 | Extensive peroxynitrite activity during progressive stages of central nervous system inflammation显示文摘 | Roel C van der Veen David R | 1997 | J Neuroimmunol1997，77，： | 1 |
| 8 | Effects of intermittent hypoxic training on amino and fatty acid oxidative combustion in human permeabilized muscle fibers显示文摘 | ROELS B THOMAS C BENTLEY D J | 2007 | J Appl Physiol2007，102，1： | 1 |
| 9 | Urinary excretion of nomovanillic acid in workers exposed to mangenese显示文摘 | Roels H Buchet JP Msgos C | 1993 | Int Arch Occup Environ Health1993，65，2： | 1 |
| 10 | Donor Action: an international initiative to alleviate organ shortage显示文摘 | Roels L Wight C | 2001 | Prog Transplant2001，11，2： | 1 |
| 11 | Effects of Hypoxic Interval Training on Cycling Performance 显示文摘 | Roels B Millet G P Marcoux C J | 2005 | Med Sci Sports Exerc2005，37，1： | 1 |
| 12 | Construction of trans- genie drosophila by using the site-specific integrase from phage φC31 显示文摘 | Groth A C Matthew F Roel N | 2004 | Genetics2004，166，4： | 1 |
| 13 | Effects of intermittent hypoxic training on amino and fatty acid oxidative combustion in human permeabilized muscle fibers显示文摘 | ROELS B THOMAS C etal | 2007 | J Appl Physiol2007，102，1： | 1 |
| 14 | Aldehyde dehydrogenase in tobacco pollen 显示文摘 | Roel G L Camp O Kuhlemeier C | 1997 | Plant Mol Biol1997，35，： | 1 |
| 15 | Preparation of deacylated phosphoglycerides显示文摘 | ROBLES E C ROELS G F M | 1971 | Chem Phy Lipids1971，6，1： | 1 |
| 16 | Urinary excretion of homovanillic acid in workers exposed to mangenese 显示文摘 | Buchet JP Magos C Roels H | 1993 | Int Arch Occup Environ Health1993，65，2： | 1 |
| 17 | Urinary excretion of homovanillic acid in workers exposed to mangenese 显示文摘 | BUCHET JP MAGOS C ROELS H | 1993 | Int Arch Occup Environ Health1993，65，2： | 1 |
| 18 | Mechanical ventilation during experimental sepsis increases deposition of advanced glycation end products and myocardial inflammation 显示文摘 | Martin C J Roel P Hans WM | 2009 | Critical Care2009，13，3： | 1 |
| 19 | Effects of hypoxic interval training on cycling performance显示文摘 | Roels B Millet G Marcoux C | 2005 | Medicine & Science in Sports & Exercise2005，37，1： | 1 |
| 20 | WRKYtranscription factors: key components in abscisic acid signalling显示文摘 | Rushton Deena L Tripathi Prateek Rabara Roel C | 2012 | Plant Biotechnol J2012，10，1： | 1 |
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