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| 1 | Stereotactic body radiation therapy for non-small cell lung cancer:A review显示文摘Stereotactic body radiation therapy(SBRT) is the treatment of choice for medically inoperable patients with early stage non-small cell lung cancer(NSCLC). A literature search primarily based on PubMed electronic databases was completed in July 2018. Inclusion and exclusion criteria were determined prior to the search, and only prospective clinical trials were included. Nineteen trials from 2005 to 2018 met the inclusion criteria, reporting the outcomes of 1434 patients with central and peripheral early stage NSCLC. Patient eligibility,prescription dose and delivery, and follow up duration varied widely. Threeyears overall survival ranged from 43% to 95% with loco-regional control of up to 98% at 3 years. Up to 33% of patients failed distantly after SBRT at 3 years. SBRT was generally well tolerated with 10%-30% grade 3-4 toxicities and a few treatment-related deaths. No differences in outcomes were observed between conventionally fractionated radiation therapy and SBRT, central and peripheral lung tumors, or inoperable and operable patients. SBRT remains a reasonable treatment option for medically inoperable and select operable patients with early stage NSCLC. SBRT has shown excellent local and regional control with toxicity rates equivalent to surgery. Decreasing fractionation schedules have been consistently shown to be both safe and effective. Distant failure is common, and chemotherapy may be considered for select patients. However, the survival benefit of additional interventions, such as chemotherapy, for early stage NSCLC treated with SBRT remains unclear. | Kavitha M Prezzano Sung Jun Ma Gregory M Hermann Charlotte I Rivers Jorge A Gomez-Suescun Anurag K Singh | 2019 | World Journal of Clinical Oncology2019,10,1: | 10 |
| 2 | Long-term outcomes of interventions for radiation-induced xerostomia:A review显示文摘Xerostomia, or dry mouth, is a significant problem affecting quality of life in patients treated with radiation therapy for head and neck cancer. Strategies for reduction of xerostomia burden vary widely, with options including: sialagogue medications, saliva substitutes, acupuncture, vitamins, hyperbaric oxygen,submandibular gland transfer, and acupuncture or associated treatments. In this review, we sought to evaluate long-term outcomes of patients treated with various interventions for radiation-induced xerostomia. A literature search was performed using the terms 'xerostomia' and 'radiation' or 'radiotherapy'; all prospective clinical trials were evaluated, and only studies that reported 1 year follow up were included. The search results yielded 2193 studies, 1977 of which were in English. Of those, 304 were clinical trials or clinical studies. After abstract review, 23 trials were included in the review evaluating the following treatment modalities: pilocarpine(three); cevimeline(one); amifostine(eleven);submandibular gland transfer(five); acupuncture like transcutaneous electrical nerve stimulation(ALTENS)(one); hyperbaric oxygen(one); and acupuncture(one). Pilocarpine, cevimeline, and amifostine have been shown in some studies to improve xerostomia outcomes, at the cost of toxicity. ALTENS has similar efficacy with fewer side effects. Submandibular gland transfer is effective but requires an elective surgery, and thus may not always be appropriate or practical.The use of intensity-modulated radiation therapy, in addition to dose deescalation in select patients, may result in fewer patients with late xerostomia,reducing the need for additional interventions. | Sung Jun Ma Charlotte I Rivers Lucas M Serra Anurag K Singh | 2019 | World Journal of Clinical Oncology2019,10,1: | 4 |
| 3 | A practical assessment of magnetic resonance diffusion-perfusion mismatch in acute stroke: observer variation and outeome显示文摘 | Kane I Hand P J Rivers C | 2009 | Journal of Neurology2009,256,11: | 1 |
| 4 | Molecular profiling of experimental endometriosis identified gene expression patterns in common with human disease显示文摘 | Rivers E Ruiz LA | 2007 | Fertil Steril2007,87,5: | 1 |
| 5 | Measuring workplace bullying显示文摘 | Cowie H Naylor P Rivers I | 2002 | Aggression Violent Behav2002,7,: | 1 |
| 6 | Method of DNA extraction and application of multiplex polymerase chain reaetian to detect toxigenic Vibrio cholerae O1 and O139 from aquatic ecosystems显示文摘 | Lipp E K Gil AI | 2003 | Environ Mierobiol2003,5,7: | 1 |
| 7 | In-line Fabry-Perot optical waveguide filter with quasi-chirped gratings 显示文摘 | OKAI M LEALMAN I F RIVERS L J | 1996 | Electron Lett1996,32,2: | 1 |
| 8 | Investigating microbial micro-habitat structure using X-ray computed tomography显示文摘 | Nunan N Ritz K Rivers M Feeney D S Young I M | | 0,,3: | 1 |
| 9 | Types of bullying behavior and their correlates 显示文摘 | Rivers I Smith P K | 1994 | Aggressive Behavior1994,20,5: | 1 |
| 10 | The Gibbs free energy of mixing of natutal silicate liquids; An expanded regular solution approximation for the calculation of magmatic intensrve variables显示文摘 | Ghiorso M S Carmichael I S E Rivers ML | 1983 | Contrib Mineral Petrol1983,84,2: | 1 |
| 11 | Types of bullying behavior and their correlates 显示文摘 | Rivers I Smith P K | 1994 | Aggressive Behavior1994,20,: | 1 |
| 12 | Clinical utility of B-type natriuretic peptide in early severe sepsis and septic shock显示文摘 | I Rivers E P McCord J Otero R | 2007 | J Intensive Care Med2007,22,6: | 1 |
| 13 | Measuring workplace bullying显示文摘 | Cowie H Naylor P Rivers I | 2002 | Aggression Violent Behav2002,7,: | 1 |
| 14 | Differential expression of peroxisome proliferator - activated receptor subtypes during the differentiation of human keratinocytes 显示文摘 | River M Safonova I Lebrun P | 1998 | J Invest Dermatol1998,111,: | 1 |
| 15 | Energy Transfer Between Bi3+ and Pr3+ in Doped CaTiO3显示文摘 | JIA WEIYI PGREZ-ANDUJAR A RIVERS I | 2003 | Journal of The Electrochemical Society2003,150,7: | 1 |
| 16 | Types of bulying behavior and their correlates 显示文摘 | Rivers I Smith P K | 1994 | Aggressive Behavior1994,20,: | 1 |
| 17 | Intrapartum epidural analgesia and mater- nal temperature regulation显示文摘 | Goetzl L Rivers J Zighelboim I Wali A Badell M Suresh MS | 2007 | Obstet Gynecol2007,109,6: | 1 |
| 18 | Energy Transfer Between Bi^3+ and Pr^3+ in Doped CaTiO3 显示文摘 | JIA W Y PGREZ-ANDUJAR A RIVERS I | 2003 | Journal of the Electrochemical Society2003,150,7: | 1 |
| 19 | Histological changes in rat liver tumors treated with high intensity focused ultrasound 显示文摘 | Chen J Rivers I Ter Haar GR | 1993 | Ultrasound in Med Biol1993,19,: | 1 |
| 20 | Well-being among same-sex and opposite-sex at- tracted youth at school 显示文摘 | River I Noret N | 2008 | School Psychol Rev2008,37,2: | 1 |