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127篇 您的检索式:作者名="Reza G"
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1Predictive biomarkers in precision medicine and drug development against lung cancer显示文摘The molecular characterization of various cancers has shown that cancers with the same origins,histopathologic diagnoses,and clinical stages can be highly heterogeneous in their genetic and epigenetic alterations that cause tumorigenesis.A number of cancer driver genes with functional abnormalities that trigger malignant transformation and that are required for the survival of cancer cells have been identified.Therapeutic agents targeting some of these cancer drivers have been successfully developed,resulting in substantial improvements in clinical symptom amelioration and outcomes in a subset of cancer patients.However,because such therapeutic drugs often benefit only a limited number of patients,the successes of clinical development and applications rely on the ability to identify those patients who are sensitive to the targeted therapies.Thus,biomarkers that can predict treatment responses are critical for the success of precision therapy for cancer patients and of anticancer drug development.This review discusses the molecular heterogeneity of lung cancer pathogenesis;predictive biomarkers for precision medicine in lung cancer therapy with drugs targeting epidermal growth factor receptor(EGFR),anaplastic lymphoma kinase(ALK),c-ros oncogene 1 receptor tyrosine kinase[ROSl),and immune checkpoints;biomarkers associated with resistance to these therapeutics;and approaches to identify predictive biomarkers in anticancer drug development.The identification of predictive biomarkers during anticancer drug development is expected to greatly facilitate such development because it will increase the chance of success or reduce the attrition rate.Additionally,such identification will accelerate the drug approval process by providing effective patient stratification strategies in clinical trials to reduce the sample size required to demonstrate clinical benefits.Bingliang Fang Reza J Mehran John V Heymach Stephen G Swisher 2015Chinese Journal of Cancer2015,34,7:5
2Fungal diversity notes 367-490:taxonomic and phylogenetic contributions to fungal taxa显示文摘This is a continuity of a series of taxonomic papers where materials are examined,described and novel combinations are proposed where necessary to improve our traditional species concepts and provide updates on their classification.In addition to extensive morphological descriptions and appropriate asexual and sexual connections,DNA sequence data are also analysed from concatenated datasets(rDNA,TEF-a,RBP2 and b-Tubulin)to infer phylogenetic relationships and substantiate systematic position of taxa within appropriate ranks.Wherever new species or combinations are being proposed,we apply an integrative approach(morphological and molecular data as well as ecological features wherever applicable).Notes on 125 fungal taxa are compiled in this paper,including eight new genera,101 new species,two new combinations,one neotype,four reference specimens,new host or distribution records for eight species and one alternative morphs.The new genera introduced in this paper are Alloarthopyrenia,Arundellina,Camarosporioides,Neomassaria,Neomassarina,Neotruncatella,Paracapsulospora and Pseudophaeosphaeria.The new species are Alfaria spartii,Alloarthopyrenia italica,Anthostomella ravenna,An.thailandica,Arthrinium paraphaeospermum,Arundellina typhae,Aspergillus koreanus,Asterina cynometrae,Bertiella ellipsoidea,Blastophorum aquaticum,Cainia globosa,Camarosporioides phragmitis,Ceramothyrium menglunense,Chaetosphaeronema achilleae,Chlamydotubeufia helicospora,Ciliochorella phanericola,Clavulinopsis aurantiaca,Colletotrichum insertae,Comoclathris italica,Coronophora myricoides,Cortinarius fulvescentoideus,Co.nymphatus,Co.pseudobulliardioides,Co.tenuifulvescens,Cunninghamella gigacellularis,Cyathus pyristriatus,Cytospora cotini,Dematiopleospora alliariae,De.cirsii,Diaporthe aseana,Di.garethjonesii,Distoseptispora multiseptata,Dis.tectonae,Dis.tectonigena,Dothiora buxi,Emericellopsis persica,Gloniopsis calami,Helicoma guttulatum,Helvella floriforma,H.oblongispora,Hermatomyces subiculosa,Juncaceicola italica,Lactarius dirkii,Lentithecium unicellulare,Le.voraginesporum,Leptosphaeria cirsii,Leptosphaeria irregularis,Leptospora galii,Le.thailandica,Lindgomyces pseudomadisonensis,Lophiotrema bambusae,Lo.fallopiae,Meliola citri-maximae,Minimelanolocus submersus,Montagnula cirsii,Mortierella fluviae,Muriphaeosphaeria ambrosiae,Neodidymelliopsis ranunculi,Neomassaria fabacearum,Neomassarina thailandica,Neomicrosphaeropsis cytisi,Neo.cytisinus,Neo.minima,Neopestalotiopsis cocoe¨s,Neopestalotiopsis musae,Neoroussoella lenispora,Neotorula submersa,Neotruncatella endophytica,Nodulosphaeria italica,Occultibambusa aquatica,Oc.chiangraiensis,Ophiocordyceps hemisphaerica,Op.lacrimoidis,Paracapsulospora metroxyli,Pestalotiopsis sequoiae,Peziza fruticosa,Pleurotrema thailandica,Poaceicola arundinis,Polyporus mangshanensis,Pseudocoleophoma typhicola,Pseudodictyosporium thailandica,Pseudophaeosphaeria rubi,Purpureocillium sodanum,Ramariopsis atlantica,Rhodocybe griseoaurantia,Rh.indica,Rh.luteobrunnea,Russula indoalba,Ru.pseudoamoenicolor,Sporidesmium aquaticivaginatum,Sp.olivaceoconidium,Sp.pyriformatum,Stagonospora forlicesenensis,Stagonosporopsis centaureae,Terriera thailandica,Tremateia arundicola,Tr.guiyangensis,Trichomerium bambusae,Tubeufia hyalospora,Tu.roseohelicospora and Wojnowicia italica.New combinations are given for Hermatomyces mirum and Pallidocercospora thailandica.A neotype is proposed for Cortinarius fulvescens.Reference specimens are given for Aquaphila albicans,Leptospora rubella,Platychora ulmi and Meliola pseudosasae,while new host or distribution records are provided for Diaporthe eres,Di.siamensis,Di.foeniculina,Dothiorella iranica,Do.sarmentorum,Do.vidmadera,Helvella tinta and Vaginatispora fuckelii,with full taxonomic details.An asexual state is also reported for the first time in Neoacanthostigma septoconstrictum.This paper contributes to a more comprehensive update and improved identification of many ascomycetes and basiodiomycetes.Kevin D.Hyde Sinang Hongsanan Rajesh Jeewon D.Jayarama Bhat Eric H.C.McKenzie E.B.Gareth Jones Rungtiwa Phookamsak Hiran A.Ariyawansa Saranyaphat Boonmee Qi Zhao Faten Awad Abdel-Aziz Mohamed A.Abdel-Wahab Supharat Banmai Putarak Chomnunti Bao-Kai Cui Dinushani A.Daranagama Kanad Das Monika C.Dayarathne Nimali Ide Silva Asha J.Dissanayake Mingkwan Doilom Anusha H.Ekanayaka Tatiana Baptista Gibertoni Aristóteles Góes-Neto Shi-Ke Huang Subashini C.Jayasiri Ruvishika S.Jayawardena Sirinapa Konta Hyang Burm Lee Wen-Jing Li Chuan-Gen Lin Jian-Kui Liu Yong-Zhong Lu Zong-Long Luo Ishara S.Manawasinghe Patinjareveettil Manimohan Ausana Mapook Tuula Niskanen Chada Norphanphoun Moslem Papizadeh Rekhani H.Perera Chayanard Phukhamsakda Christian Richter AndréL.C.Mde A.Santiago E.Ricardo Drechsler-Santos Indunil C.Senanayake Kazuaki Tanaka T.M.D.S.Tennakoon Kasun M.Thambugala Qing Tian Saowaluck Tibpromma Benjarong Thongbai Alfredo Vizzini Dhanushka N.Wanasinghe Nalin N.Wijayawardene Hai-Xia Wu Jing Yang Xiang-Yu Zeng Huang Zhang Jin-Feng Zhang Timur S.Bulgakov Erio Camporesi Ali H.Bahkali Mohammad A.Amoozegar Lidia Silva Araujo-Neta Joseph F.Ammirati Abhishek Baghela R.P.Bhatt Dimitar Bojantchev Bart Buyck Gladstone Alves da Silva Catarina Letícia Ferreira de Lima Rafael JoséVilela de Oliveira Carlos Alberto Fragoso de Souza Yu-Cheng Dai Bálint Dima Tham Thi Duong Enrico Ercole Fernando Mafalda-Freire Aniket Ghosh Akira Hashimoto Sutakorn Kamolhan Ji-Chuan Kang Samantha C.Karunarathna Paul M.Kirk Ilkka Kytovuori Angela Lantieri Kare Liimatainen Zuo-Yi Liu Xing-Zhong Liu Robert Lücking Gianfranco Medardi Peter E.Mortimer Thi Thuong Thuong Nguyen Itthayakorn Promputtha K.N.Anil Raj Mateus A.Reck Saisamorn Lumyong Seyed Abolhassan Shahzadeh-Fazeli Marc Stadler Mohammad Reza Soudi Hong-Yan Su Takumasa Takahashi Narumon Tangthirasunun Priyanka Uniyal Yong Wang Ting-Chi Wen Jian-Chu Xu Zhong-Kai Zhang Yong-Chang Zhao Jun-Liang Zhou Lin Zhu 2016Fungal Diversity2016,,5:2
3Gray and White Matter Brain Volume in Aged Rats Raised on n-3 Fatty Acid Deficient Diets显示文摘Aneeq A Reza M Peter V G 2004Nutritional Neuroscience2004,7,1:1
4Network design approach for hub ports-shipping companies competition and coop- eration显示文摘Nasrin A Reza Z F Mark G 2013Transportation Research Part A2013,48,2:1
5Chemokine re- ceptor CCR5 expression in conjunctival epithelium of pa- tients with dry eye syndrome 显示文摘ABHA G MARTA S STEFANO B REZA D 2006Arch Ophthalmol2006,124,5:1
6Characterization of the influence of moderate temperatures on rest completion in peach 显示文摘E REZA COUVILLON G A 1987J Am Soc Hort Sci1987,112,:1
7Effect of PEG stress on germina- tion indices and seedling growth of 12 bread wheat gentypes显示文摘Taregh G Mostafa V Reza S etal 2011Ad- vances in Environmental Biology2011,5,6:1
8Sleeve Gastrectomy and Gastric Banding: Effects on Plasma Ghrelin Levels显示文摘F B Langer M A Reza Hoda A Bohdjalian F X Felberbauer J Zacherl E Wenzl K Schindler A Luger B Ludvik G Prager 2005Obesity Surgery2005,,7:1
9Volume electrical resistivityof carbon fiber cement composites显示文摘REZA F BATSON G B YAMAMURO J A 2001ACI Materials Journal2001,98,1:1
10Optical properties of Fe- doped silica films on Si 显示文摘Babonas G B Reza A Simkiene 1 2006Applied Surface Science2006,252,:1
11Incidence of arteriovenous thrombosis and the role of anticardiolipin antibodies in hemodialysis patients显示文摘Jamshid R Reza SA Abbas G 0,,:1
12Effect of drying method on micro structural changes of apples 显示文摘Reza G Askari Zahra Emam - Djomeh Mohammad All Mousavi 2004IDS 2004 Proceedings Brazil2004,8,:1
13Multi-class support vector machine classifier applied to hyper-spectral data显示文摘PAUL G REZA A 2002IEEE Transactions on System Theory2002,,3:1
14Efficacy of memorial herbal on prevention of electroconvulsive therapy - induced memory impairment in mood disorder patients显示文摘Mousavi SG Mohsen G Reza MM 2012Int J Prev Med2012,3,7:1
15Effects of water recycling in hydrothermal carbonization of loblolly pine 显示文摘Uddin M H Reza M T Joan G L 2014Environmental Progress & Sustainable Energy2014,33,4:1
16Effects of water recycling in hydrothermal carbonization of loblolly pine 显示文摘Uddin M H Reza M T Joan G L 2014Environmental Progress & Sustainable Energy2014,33,4:1
17Application of the PSO-SVR model forrecognition of control chart patterns 显示文摘Vahid R Ata E Reza G 2010ISA Transactions2010,49,:1
18A New Molecularly Imprinted Polymer ( MIP ) - Based Electrochemical Sensor for Monitoring 2, 4, 6- trinitrotoluene (TNT) in Natural Waters and Soil Samples显示文摘ALIZADEH T ZARE M REZA G M 2010Biosensors and Bioelectronics2010,25,5:1
19Piperlongumine and its analogs down-regulate expression of c-Met in renal cell carcinoma显示文摘Konstantin Golovine Peter Makhov Sei Naito Henish Raiyani Jeffrey Tomaszewski Reza Mehrazin Alexei Tulin Alexander Kutikov Robert G Uzzo Vladimir M Kolenko 2015Cancer Biology & Therapy2015,,:1
20Effect of PEG stress on germination indices and seedling growth of 12 bread wheat gentypes 显示文摘TAREGH G MOSTAFA V REZA S 2011Advances in Environmental Biology2011,,6:1
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