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249篇 您的检索式:作者名="Randolph B"
    题名 作者 年代 出处 被引量
1Cockcroft-gault revisited: New de-liver-ance on recommendations for use in cirrhosis显示文摘The Cockcroft-Gault(CG) equation has become perhaps the most popular practical approach for estimating renal function among health care professionals. Despite its widespread use, clinicians often overlook not only the limitations of the original serum creatinine(SCr) based equation, but also may not appreciate the validity of the many variations used to compensate for these limitations. For cirrhotic patients in particular, the underlying pathophysiology of the disease contributes to a falsely low SCr, thereby overestimating renal function with use of the CG equation in this population. We reviewed the original CG trial from 1976 along with data surrounding clinician specific alterations to the CG equation that followed through time. These alterations included different formulas for body weight in obese patients and the 'rounding up' approach in patients with low SCr. Additionally, we described the pathophysiology and hemodynamic changes that occur in cirrhosis; and reviewed several studies that attempted to estimate renal function in this population. The evidence we reviewed regarding the most accurate manipulation of the original CG equation to estimate creatinine clearance(Cr Cl) was inconclusive. Unfortunately, the homogeneity of the patient population in the original CG trial limited its external validity. Elimination of body weight in the CG equation actually produced the estimate closest to the measure Cr Cl. Furthermore, 'rounding up' of SCr values often underestimated Cr Cl. This approach could lead to suboptimal dosing of drug therapies in patients with low SCr. In cirrhotic patients, utilization of SCr based methods overestimated true renal function by about 50% in the literature we reviewed.Gianni B Scappaticci Randolph E Regal 2017World Journal of Hepatology2017,9,3:2
2International pediatric sepsis consensus conference:definitions for sepsis and organ dysfunction in pediatrics显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
3Cochrane review:Corti-costeroids for the prevention and treatment of post-extubation stridor in neonates,children and adults显示文摘Markovitz B Randolph A Khemani R G 0,,:1
4International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
5Full-length cDNAs fromchicken bursal lymphocytes to facilitate gene function analysis显示文摘Randolph B Andrzej M Hiroshi 2007Genome Biol2007,6,1:1
6International pediatric sepsis consensus conference:definitions for sepsis and organ dysfunction in pediatrics显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
7International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics 显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
8International pediatric sepsis consensus conference:definitions for sepsis and organ dys- function in pediatrics显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
9International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics 显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
10International pediatric sepsis consensus conference:definitions for sepsis and organ dysfunction in pediatrics显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
11Corticosteroids for the prevention of reintubation and postextubation stridor in pediatric patients: a meta-analysis显示文摘Markovitz B P Randolph A G 2002Pediatr Crit Care Med2002,3,3:1
12International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics 显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
13International pediatric sepsis consensus conference: definitions for sepsis and organdysfunction in pediatrics显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,1:1
14International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics 显示文摘Goldstein B Giroir B Randolph A 2005Pediatr Crit Care Med2005,6,:1
15International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics显示文摘Goldstein B Giroir B Randolph A et a1 2005Pediatr Crit Care Med2005,6,1:1
16Hydrogen bonding between sugar and protein is responsihle for inhibition of dehydration-induced protein unfolding显示文摘Allison SD Chang B Randolph TW 0,,02:1
17显示文摘Michael V D P Randolph K B Ralph J B 1995Journal of Fluorine Chemistry1995,,71:1
18A prospective study of bone density and pregnancy after an extended period of lactation with bone loss 显示文摘Sowers M Randolph J Shapiro B 1995Obstet Gynecol1995,85,:1
19International pediatric sepsis consensus conference:definitions for sepsis and organ dysfunction in pediatrics显示文摘Goldstein B Giroir B Randolph A 0,,01:1
20Providing social support may be more beneficial than receiving it: Results from a prospective study of mortality显示文摘Stephanie L B Randolph M N Amiram D V Dylan M S 2003Psychology Science2003,,4:1
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