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| 1 | 0Adipose-derived stem cells: Implications in tissue regeneration显示文摘Adipose-derived stem cells(ASCs) are mesenchymal stem cells(MSCs) that are obtained from abundant adipose tissue, adherent on plastic culture flasks, can be expanded in vitro, and have the capacity to differ-entiate into multiple cell lineages. Unlike bone marrow-derived MSCs, ASCs can be obtained from abundant adipose tissue by a minimally invasive procedure, which results in a high number of cells. Therefore, ASCs are promising for regenerating tissues and organs dam-aged by injury and diseases. This article reviews the implications of ASCs in tissue regeneration. | Wakako Tsuji J Peter Rubin Kacey G Marra | 2014 | World Journal of Stem Cells2014，6，3： | 19 |
| 2 | Protective role of PI3-kinase/Akt/eNOS signaling in mechanical stress through inhibition of p38 mitogenactivated protein kinase in mouse lung显示文摘 | Xin-qi PENG Mahendra DAMARLA Jarrett SKIRBALL Stephanie NONAS Xiao-ying WANG Eugenia J HAN Emile J HASAN Xuan CAO Adel BOUEIZ Rachel DAMICO Rubin M TUDER Alfred M SClUTO Dana R ANDERSON Joe GNGARCIA David A KASS Paul M HASSOUN Jun-tian ZHANG | 2010 | Acta Pharmacologica Sinica2010，31，2： | 6 |
| 3 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 3 |
| 4 | Immune checkpoint inhibitor-mediated colitis in gastrointestinal malignancies and inflammatory bowel disease显示文摘Immune checkpoint inhibitors(ICI)have markedly changed the landscape of cancer therapy.By re-invigorating the immune system against tumors,ICI provide novel therapeutic options for a broad variety of malignancies,including many gastrointestinal(GI)cancers.However,these therapies can also induce autoimmune-like side effects in healthy tissue across the body.One of the most common of these side effects is ICI-mediated colitis and diarrhea(IMC).Here,we review the incidence and risk of IMC in ICI therapy,with a focus on what is known regarding IMC in patients with GI malignancies.We also discuss data available on the use of ICI and risk of IMC in patients with pre-existing inflammatory bowel disease,as these patients may have increased risk of IMC due to their underlying intestinal pathology. | Alexa R Weingarden Samuel J S Rubin John Gubatan | 2021 | World Journal of Gastrointestinal Oncology2021，13，8： | 3 |
| 5 | Antimicrobial peptides and the gut microbiome in inflammatory bowel disease显示文摘Antimicrobial peptides(AMP)are highly diverse and dynamic molecules that are expressed by specific intestinal epithelial cells,Paneth cells,as well as immune cells in the gastrointestinal(GI)tract.They play critical roles in maintaining tolerance to gut microbiota and protecting against enteric infections.Given that disruptions in tolerance to commensal microbiota and loss of barrier function play major roles in the pathogenesis of inflammatory bowel disease(IBD)and converge on the function of AMP,the significance of AMP as potential biomarkers and novel therapeutic targets in IBD have been increasingly recognized in recent years.In this frontier article,we discuss the function and mechanisms of AMP in the GI tract,examine the interaction of AMP with the gut microbiome,explore the role of AMP in the pathogenesis of IBD,and review translational applications of AMP in patients with IBD. | John Gubatan Derek R Holman Christopher J Puntasecca Danielle Polevoi Samuel JS Rubin Stephan Rogalla | 2021 | World Journal of Gastroenterology2021，27，43： | 3 |
| 6 | The propertiesof HDL in genetically engineered mice 显示文摘 | Schultz J R Rubin E M | 1994 | Curn Opin Lipidol1994，5，： | 2 |
| 7 | 糖尿病、糖尿病前期与亚临床心肌损害发生率显示文摘众所周知,处于糖尿病前期者和糖尿病患者存在较高的心血管事件发生风险。然而,糖尿病前期和糖尿病与亚临床心肌损害发生间的关系尚不明确。方法与结果:应用高敏心肌肌钙蛋白T (highly sensitive cardiac troponin T hs-cTnT)分析,测定社区动脉粥样硬化风险研究中9331例受试者两个时间点(间隔6年)的心肌肌钙蛋白T(cardiac troponin T,cTnT)水平,所有受试者为无糖尿病或处于糖尿病前期,或糖尿病不伴心血管疾病(包括心电图检测出来的无临床症状的心肌梗死)。 | Selvin E Lazo M Chen Y Shen L Rubin J McEvoy JW Hoogeveen RC Sharrett AR Ballantyne CM Coresh J 刘莉 | 2014 | 中华高血压杂志2014，22，9： | 2 |
| 8 | Doppler ultrasound color flow imaging in the study of breast cancer: preliminary findings显示文摘 | Adler D D Carson P L Rubin J M | 1990 | Ultrasound MedBiol1990，16，6： | 1 |
| 9 | An ablnitio Post-Hartree-Foek Comparative Study of 5-Azaeytosine and Cytosine and Their Dimers with Guanine显示文摘 | Podolyan Y Rubin Y V Leszeynski J | 2000 | J Phys Chem A2000，104，44： | 1 |
| 10 | Orbital reconstruction using porous polyethylene sheets 显示文摘 | RUBIN P A BILYK J R SHORE J W | 1994 | Ophthalmology1994，101，10： | 1 |
| 11 | What the 'good language learner' can teach us 显示文摘 | | 1975 | TESOL Quarterly1975，9，1： | 1 |
| 12 | Potent inhibitors of the hedgehog signaling path- way显示文摘 | BRUNTON S A STIBBARD J H A RUBIN L L | 2008 | J Med Chem2008，51，5： | 1 |
| 13 | Molecular pathways mediating mechanical signaling in bone 显示文摘 | Rubin J Rubin C Jacobs CR | 2006 | Gene2006，15，367： | 1 |
| 14 | Circulating IL-6 as a predictor of radiation pneumonitis 显示文摘 | Chen Y Rubin P Williams J | 2001 | Int J adiat Oncol Biol Phys2001，49，3： | 1 |
| 15 | Unna' s boot us polyurethane foam dressings for the treatment of venous ulceration 显示文摘 | Rubin JR Alexander J Plecha E J | 1990 | Arch Surg1990，125，4： | 1 |
| 16 | Serum carcinoembryonic antigen as an adjunct to preoperative staging of lung cancer显示文摘 | Rubins JB Dunitz J Rubins HB | 1998 | J Thorac Cardiovasc1998，116，3： | 1 |
| 17 | Can strategy instruction improve listening comprehension?显示文摘 | Thompson I Rubin J | 1996 | Foreign Language Annals1996，，293： | 1 |
| 18 | Reappriaisal of partial lateral internal sphineterotomy 显示文摘 | Pernikoff BJ Eisenstat TE Rubin R J | 1994 | Dis Colon Rectum1994，37，10： | 1 |
| 19 | Idiopathic orbital intlammation: distribution, clinical features, and treatment outcome 显示文摘 | Yuen S J Rubin PA | 2003 | Arch Ophthalmol2003，121，4： | 1 |
| 20 | A model of intertemporal emission trading, banking and borrowing显示文摘 | RUBIN J | 1996 | Journal of Environmental E- conomics and Management1996，31，16： | 1 |
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