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| 1 | Cost-utility of molecular adsorbent recirculating system treatment in acute liver failure显示文摘AIM:To determine the short-term cost-utility of mo-lecular adsorbent recirculating system(MARS) treatment in acute liver failure(ALF).METHODS:A controlled retrospective study was conducted with 90 ALF patients treated with MARS from 2001 to 2005.Comparisons were made with a historical control group of 17 ALF patients treated from 2000 to 2001 in the same intensive care unit(ICU) specializing in liver diseases.The 3-year outcomes and number of liver transplantations were recorded.All direct liver disease-related medical expenses from 6 mo before to 3 years after ICU treatment were determined for 31 MARS patients and 16 control patients.The health-related quality of life(HRQoL) before MARS treatment was estimated by a panel of ICU doctors and after MARS using a mailed 15D(15-dimensional generic healthrelated quality of life instrument) questionnaire.The HRQoL,cost,and survival data were combined and the incremental cost/quality-adjusted life years(QALYs) was calculated.RESULTS:In surviving ALF patients,the health-related quality of life after treatmeant was generally high and comparable to the age-and gender-matched general Finnish population.Compared to the controls,the average cost per QALY was considerably lower in the MARS group(64 732€ vs 133 858€) within a timeframe of 3.5 years.The incremental cost of standard medical treatment alone compared to MARS was 10 928€,and the incremental number of QALYs gained by MARS was 0.66.CONCLUSION:MARS treatment combined with standard medical treatment for ALF in an ICU setting is more cost-effective than standard medical treatment alone. | Taru Kantola Suvi Mklin Anna-Maria Koivusalo Pirjo Rsnen Anne Rissanen Risto Roine Harri Sintonen Krister Hckerstedt Helena Isoniemi | 2010 | World Journal of Gastroenterology2010，16，18： | 3 |
| 2 | Identifying suspended particles using isotope ratios显示文摘 | Cornett R J Chant L A Risto B A | 1994 | Hydrobiologia1994，284，： | 1 |
| 3 | Implementation and outcome of thrombolysis with alteplase 3–4·5 h after an acute stroke: an updated analysis from SITS-ISTR显示文摘 | Niaz Ahmed Nils Wahlgren Martin Grond Michael Hennerici Kennedy R Lees Robert Mikulik Mark Parsons Risto O Roine Danilo Toni Peter Ringleb | 2010 | Lancet Neurology2010，，9： | 1 |
| 4 | Activation of the Bone Morphogenetic Protein slignaling pathway induces inhibin Bsubunit mrna and secreted inhibin B levels in cultured human granu losa-luteal cells 显示文摘 | Risto J Jonas B Taneli R | 2002 | J Clin Endocrinol Metab2002，87，3： | 1 |
| 5 | Implementation and outcome of thrombolysis with alteplase 3–4·5 h after an acute stroke: an updated analysis from SITS-ISTR显示文摘 | Niaz Ahmed Nils Wahlgren Martin Grond Michael Hennerici Kennedy R Lees Robert Mikulik Mark Parsons Risto O Roine Danilo Toni Peter Ringleb | 2010 | Lancet Neurology2010，，9： | 1 |
| 6 | Strategic flexibility in open innovation-designing business models for open source software显示文摘 | RISTO R MIKA W KRISTIAN M | 2012 | European Journal of Marketing2012，46，10： | 1 |
| 7 | Minimum loss reconfiguration of unbalanced distribution networks显示文摘 | VESMA B DRAGOSLAV R RISTO A | 1997 | IEEE Trans on Power Delivery1997，12，1： | 1 |
| 8 | Chemical composition and size of particles in emissions of a coal-fired power plant with flue gas desulfurization显示文摘 | Karri Saarnio Anna Frey Jarkko V. Niemi Hilkka Timonen Topi R?nkk? Panu Karjalainen Mika Vestenius Kimmo Teinil? Liisa Pirjola Ville Niemel? Jorma Keskinen Anna H?yrinen Risto Hillamo | 2014 | Journal of Aerosol Science2014，，： | 1 |
| 9 | Deletion of GSK-3[beta] in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation显示文摘 | Kerkela Risto Kockeritz Lisa MacAulay Katrina Zhou Jibin Doble Bradley W Beahm Cara Greytak Sarah Woulfe Kathleen Trivedi Chinmay M Woodgett James R Epstein Jonathan A Force Thomas Huggins Gordon S | 2008 | Journal of Clinical Investigation2008，，11： | 1 |
| 10 | Identifying resuspended particles using isotope ratios显示文摘 | Cornett R J Chant L A Risto B A | 1994 | Hydrobiologia1994，284，： | 1 |
| 11 | A stochastic method for robustness analysis in sorting problems显示文摘 | Tommi T Jose R F Risto L | 2009 | European Journal of Operational Research2009，192，1： | 1 |
| 12 | Identifying resuspended particles using isotope ratios显示文摘 | Cornett R J Chant L A Risto B A | 1994 | Hydrobiologia1994，284，： | 1 |
| 13 | Inkjet printed System-in-Package design and manufacturing显示文摘 | Jani Miettinen Ville Pekkanen Kimmo Kaija Pauliina Mansikkam?ki Juha M?ntysalo Matti M?ntysalo Juha Niittynen Jussi Pekkanen Taavi Saviauk Risto R?nkk? | 2008 | Microelectronics Journal2008，，12： | 1 |
| 14 | Drought stress ahers the concentration of wood terpenoids in scots pine and Norway spruce seedlings显示文摘 | SATU T MANNINEN A M RISTO R | 2003 | Journal of Chemical Ecology2003，29，9： | 1 |
| 15 | Activation of the bone morphogenetic protein signaling pathway induces inhibin B-subunit mRNA and secreted inhibin B levels in cultured human granulose-luteal cells显示文摘 | Risto J Jonas B Taneli R | 2002 | J Clin Endocrinol Metab2002，87，3： | 1 |
| 16 | 急性缺血性卒中发病3~4.5h行阿替普酶溶栓治疗(SITS—ISTR):一项观察性研究显示文摘背景 急性缺血性卒中发病3h内行阿替普酶静脉溶栓治疗是行之有效的治疗方法,而一项针对各相关随机对照试验进行的荟萃分析提示,急性缺血性卒中发病后4.5h内行阿替普酶治疗也有获益。作者分别选取在发病后3h内以及3~4.5h之间行阿替普酶治疗的急性缺血性卒中病例,对其疗效进行比较研究。试验选取的病例均由卒中治疗安全实施组织(SITS)登记注册,SITS是属于国际卒中溶栓治疗登记处(ISTR)的一个基于网络的前瞻性审查机构。 | Nils Wahlgren Niaz Ahmecl Antoni Davalos Werner Hack Monica Millan Keith Muir Risto O Roine Danilo Toni Kennedy R Lees | 2009 | 世界临床医学2009，，5： | 0 |
| 17 | Research agenda for the Russian Far East and utilization of multiplatform comprehensive environmental observations显示文摘The Russian Far East is a region between China and the Russian Arctic with a diverse climatological,geophysical,oceanic,and economical characteristic.The southern region is located in the Far East monsoon sector,while the northern parts are affected by the Arctic Ocean and cold air masses penetrating far to the south.Growing economic activities and traffic connected to the China Belt and Road Initiative together with climate change are placing an increased pressure upon the Russian Far East environment.There is an urgent need to improve the capacity to measure the atmospheric and environmental pollution and analyze their sources and to quantify the relative roles of local and transported pollution emissions in the region.In the paper,we characterize the current environmental and socio-economical landscape of the Russian Far East and summarize the future climate scenarios and identify the key regional research questions.We discuss the research infrastructure concept,which is needed to answer the identified research questions.The integrated observations,filling in the critical observational gap at the Northern Eurasian context,are required to provide state-of-the-art observations and enable follow-up procedures that support local,regional,and global decision making in the environmental context. | Tuukka Petäjä Kirill S.Ganzei Hanna K.Lappalainen Ksenia Tabakova Risto Makkonen Jouni Räisänen Sergey Chalov Markku Kulmala Sergej Zilitinkevich Petr Ya Baklanov Renat B.Shakirov Natalia V.Mishina Evgeny G.Egidarev Igor I.Kondrat’ev | 2021 | International Journal of Digital Earth2021，14，3： | 0 |
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