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19篇 您的检索式:作者名="R.Simon"
    题名 作者 年代 出处 被引量
1充血性心力衰竭患者室性心律失常与心脏性猝死显示文摘充血性心力衰竭(CHF)患者室性心律失常(VA)和心脏性猝死(SCD)均较常见,然而其间的确切关系至今不明[1~3]。我们应用24小时动态心电图前瞻性研究一组CHF患者的室性心律失常,并作随访观察,以探讨其易患因素及其与心脏性猝死的关系。资料和方法临...傅国胜 A.MEISSNER R.SIMON 1999中华心律失常学杂志1999,3,1:17
2复极离散度与充血性心力衰竭患者致命性快速室性心律失常的关系显示文摘目的探讨复极离散度与充血性心力衰竭(CHF)患者发生致命性室性快速心律失常的关系。方法对25例自发性致命性室性快速心律失常的 CHF 患者和57例无室性快速心律失常的 CHF患者进行病例对照研究,以 QT/JT 及 QTc/JTc 间期最大差值(d)及其变异系数(cv)计算复极离散度。结果单因素分析筛选出2个体表心电图参数(QTc、JTc)和4个复极离散度参数(JTcd、QTcd、JTcv 及JTccv)和室性快速心律失常相关(P<0.05),多因素分析显示 JTcd 和 QTc 为室性快速心律失常独立危险因素。结论复极离散度增加是 CHF 患者发生致命性室性快速心律失常和心脏性猝死危险的标志。傅国胜 A.Meissner R.Simon 1998中华心律失常学杂志1998,2,2:7
3Adversarial Learning for Distant Supervised Relation Extraction显示文摘Recently,many researchers have concentrated on using neural networks to learn features for Distant Supervised Relation Extraction(DSRE).These approaches generally use a softmax classifier with cross-entropy loss,which inevitably brings the noise of artificial class NA into classification process.To address the shortcoming,the classifier with ranking loss is employed to DSRE.Uniformly randomly selecting a relation or heuristically selecting the highest score among all incorrect relations are two common methods for generating a negative class in the ranking loss function.However,the majority of the generated negative class can be easily discriminated from positive class and will contribute little towards the training.Inspired by Generative Adversarial Networks(GANs),we use a neural network as the negative class generator to assist the training of our desired model,which acts as the discriminator in GANs.Through the alternating optimization of generator and discriminator,the generator is learning to produce more and more discriminable negative classes and the discriminator has to become better as well.This framework is independent of the concrete form of generator and discriminator.In this paper,we use a two layers fully-connected neural network as the generator and the Piecewise Convolutional Neural Networks(PCNNs)as the discriminator.Experiment results show that our proposed GAN-based method is effective and performs better than state-of-the-art methods.Daojian Zeng Yuan Dai Feng Li R.Simon Sherratt Jin Wang 2018Computers, Materials & Continua2018,,4:4
4QT离散度与充血性心力衰竭患者心脏性猝死的关系显示文摘目的:探讨QT离散度与充血性心力衰竭(CHF)患者心脏性猝死的关系。方法:分析163例CHF病人的QT离散度、血流动力学、心功能及室性心律失常。QT离散度以12导联体表心电图上最长和最短的QT和JT间期之差及其变异系数计算。结果:平均随访26±15个月,心脏性猝死34例,非猝死型心脏性死亡25例(心力衰竭19例,心肌梗塞6例),非心脏性死亡和接受心脏移植7例,存活97例。心脏性猝死组各QT离散度参数均显著高于存活组和非猝死组,而后两者之间无差异。多因素Cox模型分析示,QT离散度增加是心脏性猝死独立危险因素;JTc离散度≥85ms组和<85ms组3年非猝死生存率分别为30.8%和96.6%。结论:QT离散度增加是心脏性猝死独立危险因素,QT离散度检测有助于识别CHF心脏性猝死高危患者。傅国胜 单江 A.Meissner R.Simon 1999浙江大学学报(医学版)1999,28,1:4
5Prognostic value of Doppler transmitral filling patterns in patients with chronic heart failure显示文摘Background Chronic heart failure is a significant cause of cardiovascular morbidity and mortality.This study tested the hypothesis that restrictive filling pattern may provide useful prognostic data for identifying patients with chronic heart failure at high risk of all-cause cardiac death.Methods Ninety patients with chronic heart failure [70 men and 20 women, mean age (58.1±11.6) years] were investigated and followed for (18. 8±7. 9) months. During this period, 14 patients died of progressive pump failure, 12 patients underwent heart transplantation, 5 patients died suddenly, and 2 patients died of acute myocardial infarction. A new criterion, the restrictive filling index (RFI), was designed to subgroup patients into a restrictive and a nonrestrictive group.Results Patients with restrictive filling pattern had a more severe left ventricular dysfunction and a higher cardiac mortality. Analysis by the Kaplan-Meier method revealed that patients in the RFI≥1 and RFI<1 groups had a cardiac events-free survival rate of 52% versus 94% at 1 year, and 27. 5% versus 92% at 2 years, respectively. The multivariate Cox proportional hazard model selected RFI as the most powerful prognostic factor (χ2 =8. 8017, P =0. 0030) for all-cause cardiac death.郑哲岚 A.Meissner B.Hausmann H.Alexander R.Simon 2004Chinese Medical Journal2004,17,2:3
6Optimal Coverage Multi-Path Scheduling Scheme with Multiple Mobile Sinks for WSNs显示文摘Wireless Sensor Networks(WSNs)are usually formed with many tiny sensors which are randomly deployed within sensing field for target monitoring.These sensors can transmit their monitored data to the sink in a multi-hop communication manner.However,the‘hot spots’problem will be caused since nodes near sink will consume more energy during forwarding.Recently,mobile sink based technology provides an alternative solution for the long-distance communication and sensor nodes only need to use single hop communication to the mobile sink during data transmission.Even though it is difficult to consider many network metrics such as sensor position,residual energy and coverage rate etc.,it is still very important to schedule a reasonable moving trajectory for the mobile sink.In this paper,a novel trajectory scheduling method based on coverage rate for multiple mobile sinks(TSCR-M)is presented especially for large-scale WSNs.An improved particle swarm optimization(PSO)combined with mutation operator is introduced to search the parking positions with optimal coverage rate.Then the genetic algorithm(GA)is adopted to schedule the moving trajectory for multiple mobile sinks.Extensive simulations are performed to validate the performance of our proposed method.Jin Wang Yu Gao Chang Zhou R.Simon Sherratt Lei Wang 2020Computers, Materials & Continua2020,,2:3
7充血性心力衰竭心脏性猝死危险因素分析显示文摘充血性心力衰竭(CHF)中35%~50%为心脏性猝死(SCD)。本文对一组CHF患者进行了随访研究,旨在探讨CHF患者发生猝死的危险因素。一、资料与方法:病人为1991年1月至1993年11月的住院者。入选者心衰临床病程≥3月,心功能(NYHA)Ⅱ~Ⅳ级,左室造影时射血分数(LVEF)≤40%,左、右心导管及冠脉造影诊断为缺血性(ICMP)或扩张型心肌病(DCMP)。24小时动态心电图中室性心律失常(VA)按Lown法分级,Ⅳa、Ⅳb、Ⅴ级定义为复杂型VA,0~Ⅲ级为简单型VA。描记标准12导联心电图测量QT、JT及R-R间期,傅国胜 单江 A.Meissner R.Simon 1998中华流行病学杂志1998,19,4:3
8Economies of scale in fimancial institution:A study in life assurance显示文摘Houston D R.Simon 0,,38:1
9充血性心力衰竭患者预后因素的研究——动脉血压及心脏收缩功能的影响显示文摘目的:探讨充血性心力衰竭(CHF)患者的预后因素。方法:前瞻性研究163例CHF患者临床、血流动力学及心脏收缩功能的预后价值,用多因素Cox回归模型分析各因素对预后的影响。结果:平均随访29个月,心脏性死亡59例,其中猝死34例,泵衰竭死亡19例,心肌梗死死亡6例。生存率分析示主动脉平均压≤90mmHg、肺动脉平均压≥25mmHg、QTc≥440ms、射血分数≤25%及有束支阻滞者,生存率显著降低。多因素分析显示平均主动脉压、平均肺动脉压和QT是心脏性死亡的独立危险因素。结论:低血压、QTc延长及伴肺动脉高压者预后不良,治疗中应防止过度降压和延长心肌复极。傅国胜 A.Meissner R.Simon 2000中国医药导刊2000,2,2:1
10Data Secure Storage Mechanism of Sensor Networks Based on Blockchain显示文摘As the number of sensor network application scenarios continues to grow,the security problems inherent in this approach have become obstacles that hinder its wide application.However,it has attracted increasing attention from industry and academia.The blockchain is based on a distributed network and has the characteristics of non-tampering and traceability of block data.It is thus naturally able to solve the security problems of the sensor networks.Accordingly,this paper first analyzes the security risks associated with data storage in the sensor networks,then proposes using blockchain technology to ensure that data storage in the sensor networks is secure.In the traditional blockchain,the data layer uses a Merkle hash tree to store data;however,the Merkle hash tree cannot provide non-member proof,which makes it unable to resist the attacks of malicious nodes in networks.To solve this problem,this paper utilizes a cryptographic accumulator rather than a Merkle hash tree to provide both member proof and non-member proof.Moreover,the number of elements in the existing accumulator is limited and unable to meet the blockchain’s expansion requirements.This paper therefore proposes a new type of unbounded accumulator and provides its definition and security model.Finally,this paper constructs an unbounded accumulator scheme using bilinear pairs and analyzes its performance.Jin Wang Wencheng Chen Lei Wang R.Simon Sherratt Osama Alfarraj Amr Tolba 2020Computers, Materials & Continua2020,,12:1
11Unsupervised Log Anomaly Detection Method Based on Multi-Feature显示文摘Log anomaly detection is an important paradigm for system troubleshooting.Existing log anomaly detection based on Long Short-Term Memory(LSTM)networks is time-consuming to handle long sequences.Transformer model is introduced to promote efficiency.However,most existing Transformer-based log anomaly detection methods convert unstructured log messages into structured templates by log parsing,which introduces parsing errors.They only extract simple semantic feature,which ignores other features,and are generally supervised,relying on the amount of labeled data.To overcome the limitations of existing methods,this paper proposes a novel unsupervised log anomaly detection method based on multi-feature(UMFLog).UMFLog includes two sub-models to consider two kinds of features:semantic feature and statistical feature,respectively.UMFLog applies the log original content with detailed parameters instead of templates or template IDs to avoid log parsing errors.In the first sub-model,UMFLog uses Bidirectional Encoder Representations from Transformers(BERT)instead of random initialization to extract effective semantic feature,and an unsupervised hypersphere-based Transformer model to learn compact log sequence representations and obtain anomaly candidates.In the second sub-model,UMFLog exploits a statistical feature-based Variational Autoencoder(VAE)about word occurrence times to identify the final anomaly from anomaly candidates.Extensive experiments and evaluations are conducted on three real public log datasets.The results show that UMFLog significantly improves F1-scores compared to the state-of-the-art(SOTA)methods because of the multi-feature.Shiming He Tuo Deng Bowen Chen R.Simon Sherratt Jin Wang 2023Computers, Materials & Continua2023,,7:1
12Distributed Secure Storage Scheme Based on Sharding Blockchain显示文摘Distributed storage can store data in multiple devices or servers to improve data security.However,in today’s explosive growth of network data,traditional distributed storage scheme is faced with some severe challenges such as insufficient performance,data tampering,and data lose.A distributed storage scheme based on blockchain has been proposed to improve security and efficiency of traditional distributed storage.Under this scheme,the following improvements have been made in this paper.This paper first analyzes the problems faced by distributed storage.Then proposed to build a new distributed storage blockchain scheme with sharding blockchain.The proposed scheme realizes the partitioning of the network and nodes by means of blockchain sharding technology,which can improve the efficiency of data verification between nodes.In addition,this paper uses polynomial commitment to construct a new verifiable secret share scheme called PolyVSS.This new scheme is one of the foundations for building our improved distributed storage blockchain scheme.Compared with the previous scheme,our new scheme does not require a trusted third party and has some new features such as homomorphic and batch opening.The security of VSS can be further improved.Experimental comparisons show that the proposed scheme significantly reduces storage and communication costs.Jin Wang Chenchen Han Xiaofeng Yu Yongjun Ren R.Simon Sherratt 2022Computers, Materials & Continua2022,,3:1
13完全闭塞血管用激光导丝行血管成型术的临床试验显示文摘P.W.Serruys J.N.Hamburger J.J.Koolen J.Fajadet M.Haude H.Klues R.Seabra-Gomes T.Corcos C.Hamm L.Pizzuli B.Meier D.Mathey E.Flleck Y.Taeymans R.Melkert Y.Teunissen R.Simon 陈爱华 2001岭南心血管病杂志2001,7,2:0
14CDC专题会诊:预防青少年暴力显示文摘青少年暴力是指发生在10-24岁人群中的,故意以个人体力或能力威胁、伤害他人的事件,这些参与其中的年轻人或是受害者,或是侵犯者,或是目击者。典型的青少年暴力表现为年轻人伤害其他年轻人,且表现形式多有不同。可以举出的例子有:打架、欺凌、武器威胁,以及帮派有关的暴力。不同形式的青少年暴力导致的伤害形式也有不同,包括身体的伤害,例如伤残或死亡;Corinne David-Ferdon Thomas R.Simon Howard Spivak Deborah Gorman-Smith Sheila B.Savannah Robert L.Listenbee John Iskander 苏慧佳(译) 陆仁敏(审校) 2017上海预防医学2017,29,10:0
15Data Secure Storage Mechanism for IIoT Based on Blockchain显示文摘With the development of Industry 4.0 and big data technology,the Industrial Internet of Things(IIoT)is hampered by inherent issues such as privacy,security,and fault tolerance,which pose certain challenges to the rapid development of IIoT.Blockchain technology has immutability,decentralization,and autonomy,which can greatly improve the inherent defects of the IIoT.In the traditional blockchain,data is stored in a Merkle tree.As data continues to grow,the scale of proofs used to validate it grows,threatening the efficiency,security,and reliability of blockchain-based IIoT.Accordingly,this paper first analyzes the inefficiency of the traditional blockchain structure in verifying the integrity and correctness of data.To solve this problem,a new Vector Commitment(VC)structure,Partition Vector Commitment(PVC),is proposed by improving the traditional VC structure.Secondly,this paper uses PVC instead of the Merkle tree to store big data generated by IIoT.PVC can improve the efficiency of traditional VC in the process of commitment and opening.Finally,this paper uses PVC to build a blockchain-based IIoT data security storage mechanism and carries out a comparative analysis of experiments.This mechanism can greatly reduce communication loss and maximize the rational use of storage space,which is of great significance for maintaining the security and stability of blockchain-based IIoT.Jin Wang Guoshu Huang R.Simon Sherratt Ding Huang Jia Ni 2024Computers, Materials & Continua2024,78,3:0
16后退式旋切导管治疗冠状动脉阻塞性病变的初步报告显示文摘目的 评价后退式旋切导管 (PAC)治疗冠状动脉病变的有效性和安全性。方法 5 5例冠状动脉病变选用PAC导管治疗 ,其中 17例为支架内再狭窄病变 ,应用定量冠状动脉造影评价即刻和近期疗效。结果 5 5例患者手术成功率为 95 % ,PAC导管使血管最小管腔直径从 (1 0 7± 0 5 1)mm增加至 (1 98± 0 39)mm ,并发症包括血管内膜撕裂 7例 ,完全闭塞 1例 ,6个月随访造影最小管腔直径为 (1 97± 0 6 7)mm ,造影再狭窄率为 2 7%。首次介入治疗病变与支架内再狭窄病变即刻与近期疗效相同 ,向心性病变较偏心性病变有更好的即刻效果。结论 PAC旋切导管能安全有效去除冠状动脉内粥样斑块 。傅国胜 单江 M.Lins R.Simon 2001中华心血管病杂志2001,29,12:0
17比较性基因组杂交在病理学中的应用——一项新的细胞遗传学方法显示文摘新的分子病理学方法如多聚酶链反应(PCR)及荧光原位杂交(FISH)等的迅速发展,为分子病理学这一新学科带来了新进展。从近年来的一些方法中,最近又发展出比较性基因组杂交(CGH)这一在病理学中具有发展前景的崭新方法。 在病理学特别是儿童和肿瘤病理学中,此新的筛选方法具有广阔的应用领域,诸如应用于诊断、亚分类、分级以及预后估计和制订合理的治疗方案等。S.Strkel R.Simon C.Brinkschmidt J.Gronwald W.Bcker 武忠弼 1997德国医学1997,14,4:0
18Enhancing Security by Using GIFT and ECC Encryption Method in Multi-Tenant Datacenters显示文摘Data security and user privacy have become crucial elements in multi-tenant data centers.Various traffic types in the multi-tenant data center in the cloud environment have their characteristics and requirements.In the data center network(DCN),short and long flows are sensitive to low latency and high throughput,respectively.The traditional security processing approaches,however,neglect these characteristics and requirements.This paper proposes a fine-grained security enhancement mechanism(SEM)to solve the problem of heterogeneous traffic and reduce the traffic completion time(FCT)of short flows while ensuring the security of multi-tenant traffic transmission.Specifically,for short flows in DCN,the lightweight GIFT encryption method is utilized.For Intra-DCN long flows and Inter-DCN traffic,the asymmetric elliptic curve encryption algorithm(ECC)is utilized.The NS-3 simulation results demonstrate that SEM dramatically reduces the FCT of short flows by 70%compared to several conventional encryption techniques,effectively enhancing the security and anti-attack of traffic transmission between DCNs in cloud computing environments.Additionally,SEM performs better than other encryption methods under high load and in largescale cloud environments.Jin Wang Ying Liu Shuying Rao R.Simon Sherratt Jinbin Hu 2023Computers, Materials & Continua2023,,5:0
19Congestion Control Using In-Network Telemetry for Lossless Datacenters显示文摘In the Ethernet lossless Data Center Networks (DCNs) deployedwith Priority-based Flow Control (PFC), the head-of-line blocking problemis still difficult to prevent due to PFC triggering under burst trafficscenarios even with the existing congestion control solutions. To addressthe head-of-line blocking problem of PFC, we propose a new congestioncontrol mechanism. The key point of Congestion Control Using In-NetworkTelemetry for Lossless Datacenters (ICC) is to use In-Network Telemetry(INT) technology to obtain comprehensive congestion information, which isthen fed back to the sender to adjust the sending rate timely and accurately.It is possible to control congestion in time, converge to the target rate quickly,and maintain a near-zero queue length at the switch when using ICC. Weconducted Network Simulator-3 (NS-3) simulation experiments to test theICC’s performance. When compared to Congestion Control for Large-ScaleRDMA Deployments (DCQCN), TIMELY: RTT-based Congestion Controlfor the Datacenter (TIMELY), and Re-architecting Congestion Managementin Lossless Ethernet (PCN), ICC effectively reduces PFC pause messages andFlow Completion Time (FCT) by 47%, 56%, 34%, and 15.3×, 14.8×, and11.2×, respectively.Jin Wang Dongzhi Yuan Wangqing Luo Shuying Rao R.Simon Sherratt Jinbin Hu 2023Computers, Materials & Continua2023,,4:0
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