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183篇 您的检索式:作者名="Puerto"
    题名 作者 年代 出处 被引量
1电位滴定分析ASP驱采出液中表面活性剂浓度显示文摘以十二烷基磺酸钠为例,考察了利用电位滴定方法分析ASP三元复合驱采出液中表面活性剂浓度时,pH值、盐度、聚合物含量、石油酸皂浓度等因素对分析结果的影响,研究出因石油酸皂和聚合物的存在导致结果偏高的消除方法,并对方法的检出限进行研究。该方法为ASP三元驱中十二烷基磺酸钠类阴离子表面活性剂浓度的分析提供了参考。沈少春 李应成 沙鸥 George J.Hirasaki Maura Puerto Clarence A.Miller 2017石油与天然气化工2017,46,6:3
2Oral probiotic VSL #3 attenuates the circulatory disturbances of patients with cirrhosis and ascites显示文摘Diego Rincón Javier Vaquero Ana Hernando Evelyn Galindo Cristina Ripoll Marta Puerto Magdalena Salcedo Rubén Francés Ana Matilla María V. Catalina Gerardo Clemente José Such Rafael Ba?ares 2014Liver Int2014,,10:2
3Construction engineering management culture shift: Is the lowest tender offer dead?显示文摘The procurement of public construction projects must walk a fine line between the corruption of state officials and collusion of contractors. The method of awarding projects to the lowest responsible tenderer was originally implemented to guard against corruption of state officials. However, an investigation of the construction industry in the Canadian province of Quebec showed that lowest-tender-offer procurement gave rise to collusion of companies tendering for the contracts. Alternatively, bestvalue procurement has been used for decades, but here problems arise owing to the necessity of subjective judging of measures other than price to compare bids, giving rise to time-and money-consuming protests. The paper proposes a compelling argument that the construction engineering management(CEM) culture should refocus its efforts on enhancing project cost certainty rather than merely searching for means to design a project in a manner that produces the lowest initial cost, and awards the construction to the lowest tender offer that focuses on cost savings during the project development and delivery process. The difference in the two approaches is subtle but extremely important. To make the transition, the engineering management tools must be advanced to the next level.This means that all project control tools for managing cost,schedule, and technical scope must be transformed from working in the deterministic mode to the stochastic mode,thus making the probability of completing the projectwithin or below its official budget the primary decision criterion. To do so, CEMs must accept that there is a benefit in paying more for an alternative that increases cost certainty for the entire project. The authors of this paper hope that it will provide the grist for a more general dialog across all industry sectors where engineering management is practiced.Eric SCHEEPBOUWER Douglas D.GRANSBERG Carla Lopez del PUERTO 2017Frontiers of Engineering Management2017,4,1:2
4An update on the molecular biology of glioblastoma,with clinical implications and progress in its treatment显示文摘Glioblastoma multiforme(GBM)is the most aggressive and common malig-nant primary brain tumor.Patients with GBM often have poor prognoses,with a median survival of∼15 months.Enhanced understanding of the molecular biology of central nervous system tumors has led to modifications in their classifications,the most recent of which classified these tumors into new categories and made some changes in their nomenclature and grading system.This review aims to give a panoramic view of the last 3 years’findings in glioblastoma characterization,its heterogeneity,and current advances in its treatment.Several molecular parameters have been used to achieve an accurate and personalized characterization of glioblastoma in patients,including epigenetic,genetic,transcriptomic and metabolic features,as well as age-and sex-related patterns and the involvement of several noncoding RNAs in glioblastoma progression.Astrocyte-like neural stem cells and outer radial glial-like cells from the subven-tricular zone have been proposed as agents involved in GBM of IDH-wildtype origin,but this remains controversial.Glioblastoma metabolism is characterized by upregulation of the PI3K/Akt/mTOR signaling pathway,promotion of the gly-colytic flux,maintenance of lipid storage,and other features.This metabolism also contributes to glioblastoma’s resistance to conventional therapies.Tumor heterogeneity,a hallmark of GBM,has been shown to affect the genetic expresion,modulation of metabolic pathways,and immune system evasion.GBM’s aggressive invasion potential is modulated by cell-to-cell crosstalk within the tumor microenvironment and altered expressions of specific genes,such as ANXA2,GBP2,FN1,PHIP,and GLUT3.Nevertheless,the rising number of active clinical trials illustrates the efforts to identify new targets and drugs to treat this malignancy.Immunotherapy is still relevant for research purposes,given the amount of ongoing clinical trials based on this strategy to treat GBM,and neoantigen and nucleic acid-based vaccines are gaining importance due to their antitumoral activity by inducing the immune response.Furthermore,there are clinical trials focused on the PI3K/Akt/mTOR axis,angiogenesis,and tumor heterogeneity for developing molecular-targeted therapies against GBM.Other strategies,such as nanodelivery and computational models,may improve the drug pharmacokinetics and the prognosis of patients with GBM.Elena Verdugo Iker Puerto MiguelÁngel Medina 2022Cancer Communications2022,42,11:2
5Recent advances in surfactant EOR 显示文摘Hirasaki G J Miller C A Puerto M 2011SPE Journal2011,16,4:1
6A new role for reticulon-4B/NOGO- B in the intestinal epithelial barrier function and inflammatory bowel disease显示文摘Rodriguez-Feo JA Puerto M Fernandez- Mena C 2015Am J Physiol Gastrointest Liver Physiol2015,308,2:1
7Multi-eriteria minimum cost spanning tree games 显示文摘Fernandez F R Hinojosa M A Puerto J 2004European Journal of Operational Research2004,158,2:1
8Phase trial of weekly i v Vinorelbine as a single agent in first-line advanced breast cancer chemotherapy显示文摘Bruno S Puerto VL Mickiewicz E 1995Am J Clin Oncol1995,18,5:1
9Acicular metallic particles obtainedfrom al-doped goethite precursors 显示文摘NURIA O NUNEZ RAUL POZAS M PUERTO MORALES 2003Chem Mater2003,15,4:1
10On the class of controlled branching processes with random control functions 显示文摘Gonzdlez M Molina M Del Puerto I 2002JApplProb2002,39,:1
11Multi-criteria analysis with pertain information about the weighting coefficients显示文摘Carrizosa E Conde E Femandez R Puerto J 1995European Journal of Operation Research1995,81,2:1
12On the class of controlled branching processes with random control functions显示文摘González M Molina M Del Puerto I 2002J Appl Prob2002,39,:1
13On the Geometric growth in controlled branching processes with random con-trol function显示文摘Gonzdalez M Molina M Del Puerto I 2003J Appl Prob2003,40,:1
14Inducing glassy magnetism in co-ferrite nanopartieles through crystalline nanostructure 显示文摘Moya C Salas G Puerto M M 2015Journal of Materials Chemistry C2015,3,:1
15Multi-criteria minisum facility location problems显示文摘Puerto Fernandez 1999Journal Of Multi-Criteria Decision Analysis1999,5,5:1
16Center location problems on tree graphs with subtree-shaped customers显示文摘PUERTO J TAMIR A MESA J A 2008Discrete Applied Mathematics2008,156,15:1
17Limiting distribution for suhcritieal controlled branching processes with ran-dom control function显示文摘Gonzdlez M Molina M Del Puerto I 2004Stat Probab Letts2004,67,:1
18Stem cells:are they the answer to the puzzling etiology of endometriosis? 显示文摘Oliveira FR Dela Cruz C Del Puerto HL 2012Histol Histopathol2012,27,1:1
19Multi-criteria minimum cost spanning tree games显示文摘Femandez F R Hinojosa M A Puerto J 2004European Journal of Operational Research2004,158,2:1
20Evaluation of the mutagenicity and genotoxic potential of carvacrol and thymol using the Ames Salmonella test and alkaline,Endo III-and FPG-modified comet assays with the human cell line Caco-2显示文摘LLANA-RUIZ-CABELLO M MAISANABA S PUERTO M 2014Food and Chemical Toxicology2014,72,:1
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