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| 1 | Clinical features and management of primary biliary cirrhosis显示文摘Primary biliary cirrhosis(PBC),which is characterised by progressive destruction of intrahepatic bile ducts,is not a rare disease since both prevalence and incidence are increasing during the last years mainly due to the improvement of case finding strategies.The prognosis of the disease has improved due to both the recognition of earlier and indolent cases,and to the wide use of ursodeoxycholic acid(UDCA).New indicators of prog-nosis are available that will be useful especially for the growing number of patients with less severe disease.Most patients are asymptomatic at presentation.Pruri-tus may represent the most distressing symptom and,when UDCA is ineffective,cholestyramine represents the mainstay of treatment.Complications of long-standing cholestasis may be clinically relevant only in very ad-vanced stages.Available data on the effects of UDCA on clinically relevant end points clearly indicate that the drug is able to slow but not to halt the progression of the disease while,in advanced stages,the only thera-peutic option remains liver transplantation. | Andrea Crosignani Pier Maria Battezzati Pietro Invernizzi Carlo Selmi Elena Prina Mauro Podda | 2008 | World Journal of Gastroenterology2008，14，21： | 23 |
| 2 | Rapid differentiation of Old World Leishmania species by LightCycler polymerase chain reaction and melting curve analysis显示文摘 | Luc Nicolas Geneviève Milon Eric Prina | 2002 | Journal of Microbiological Methods2002，，3： | 1 |
| 3 | Thyroid reoperations:indications and risks显示文摘 | Wilson DB Staren ED Prina RA | 1998 | Am Surg1998，64，7： | 1 |
| 4 | Thrombocytosis is a marker of poor outcome in community-acquired pneumonia 显示文摘 | Prina E Ferrer M Ranzani OT | 2013 | Chest2013，143，3： | 1 |
| 5 | Incidence, 30-day case-fatality rate, and prognosis of stroke in Iquique, Chile: a 2-year community-based prospective study (PISCIS project)显示文摘 | Pablo M Lavados Claudio Sacks Liliana Prina Arturo Escobar Claudia Tossi Fernando Araya Walter Feuerhake Marcelo Galvez Rodrigo Salinas Gonzalo Alvarez | 2005 | The Lancet2005，，9478： | 1 |
| 6 | Real-time PCR for detection and quantitation of leishmania in mouse tissues 显示文摘 | NICOLAS L PRINA E LANG T | 2002 | J Clin Microbio12002，40，5： | 1 |
| 7 | Production and post-surgical modification of VEGF, tPA and PA1-1 in patients with glioma显示文摘 | Salmaggi A Croci D Prina P | 2006 | Cancer Biol Ther2006，5，2： | 1 |
| 8 | A cytoplasmically in herited mutant controlling early chloroplast development in barley seedlings 显示文摘 | Prina A R Arias M C Lainez V | 2003 | Theor Appl Genet2003，107，： | 1 |
| 9 | Development of a SYBR green I based RT-PCR assay for yellow fever virus: application in assessment of YFV infection in Aedes aegypti 显示文摘 | Dash PK Boutonnier A Prina E | 2012 | Virol J2012，9，： | 1 |
| 10 | Association between depression and hospital outcomes among older men显示文摘 | Prina AM Huisman M Yeap BB | 2013 | Canad Med Associ J2013，185，2： | 1 |
| 11 | Sorption coolers using a continuous cycle to produce 20 K for the Planck flight mission显示文摘 | BHANDARI P PRINA M BOWMAN R J | 2004 | Cryogenies2004，44，： | 1 |
| 12 | Parasitophorus vacuoles of Leishmania amazonensis infected macrophages maintain an acidic pH显示文摘 | Antoine JC Prina E Jouanne C | 1900 | Infect Immun1900，58，3： | 1 |
| 13 | Devel- opment of passively actuated thermal control valves for passive control of mechanically pumped single- phase fluid loops for space applications显示文摘 | BIRUR G PRINA M BHANDARI P | 2008 | SAE Int J Aerosp2008，1，1： | 1 |
| 14 | Incidence, 30 - daycase-fatality rate, and prognosis of stroke in Iquique, Chile: a 2- yearcommunity - based prospective study (PISCIS project) 显示文摘 | Lavados PM Sacks C Prina L | 2005 | Lancet2005，365，9478： | 1 |
| 15 | Thrombocytosis is a marker of poor outcome in community-acquired pneumonia显示文摘 | Prina E Ferrer M Ranzani OT | 2013 | Chest2013，143，3： | 1 |
| 16 | Assessment of Zr - V - Fe Getter Alloy for Gas-Gap Heat Switches 显示文摘 | Prina M Kulleck J Bowman R | 2002 | Journal of Alloys and Compounds2002，，： | 1 |
| 17 | A new mutant al lele for Xa/xa gene and its use for location of newly induced mutants in the long arm of barley chromosome 1显示文摘 | Prina A R Arias MC and dela Fueme MC | 1995 | Barley Genetics Newletter1995，25，： | 1 |
| 18 | Metabolic syndrome as a predictor of all-cause and cardiovascular mortality in type 2 diabetes:The Casale Monferrato Study显示文摘 | Bruno G Merletti F Biggeri A Bargero G Ferrero S Runzo C Prina Cerai S Pagano G Cavallo-Perin P | 2004 | Diabetes Care2004，27，11： | 1 |
| 19 | Incidence, ease-fatality rate, and prognosis of ischemie stroke subtypes in a predominantly His-panic-Mestizo population in Iquique, Chile (PISCIS pmject): a community-based incidence study显示文摘 | Lvados PM Sacks C Prina L | 2007 | Lancet Neurol2007，6，： | 1 |
| 20 | Real-time PCR for detec- tion and quantitation of leishmania in mouse tissues显示文摘 | Nicolas L Prina E Lang T | 2002 | J Clin Microbiol2002，40，5： | 1 |
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