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| 1 | Identification of SUMO Targets by a Novel Proteomic Approach in Plants显示文摘Post-translational modifications (PTMs) chemically and physically alter the properties of proteins, including their folding, subcellular localization, stability, activity, and consequently their function. In spite of their relevance, studies on PTMs in plants are still limited. Small Ubiquitin-like Modifier (SUMO) modification regulates several biological processes by affecting protein-protein interactions, or changing the subcellular localizations of the target proteins. Here, we describe a novel proteomic approach to identify SUMO targets that combines 2-D liquid chromatography, immunodetection, and mass spectrometry (MS) analyses. We have applied this approach to identify nuclear SUMO targets in response to heat shock. Using a bacterial SUMOylation system, we validated that some of the targets identified here are, in fact, labeled with SUMO1. Interestingly, we found that GIGANTEA (GI), a photoperiodic-pathway protein, is modified with SUMO in response to heat shock both in vitro and in vivo. | Gema López-Torrejón Davide Guerra Rafael Catal Julio Salinas Juan C. del Pozo | 2013 | Journal of Integrative Plant Biology2013，55，1： | 6 |
| 2 | Anti-porcine circovirus type 2(PCV2) antibody placental barrier leakage from sow to fetus: impact on the diagnosis of intra-uterine PCV2 infection显示文摘Dear Editor,Fetuses develop antibodies when they are infectedwith porcine circovirus type 2(PCV2).At abortion orbirth,both PCV2 and/or anti-PCV2 antibodies can thenbe detected.Finding anti-PCV2 antibodies in aborted fe-tuses or stillborn piglets is generally used as evidence ofan intra-uterine PCV2 infection.However,a recent anal-ysis of fetuses sent in for PCV2 diagnosis and caesare-an-derived,colostrum-deprived pigs revealed that | Dipongkor Saha Rubén Del Pozo Sacristán Nicolaas Van Renne Liping Huang Ruben Decaluwe Annelies Michiels Alfonso Lopez Rodriguez Maria José Rodrí-guez Margarita García Durán Ilse Declerk Dominiek Maes Hans J. Nauwynck | 2014 | Virologica Sinica2014，29，2： | 3 |
| 3 | Treatment of anaerobic sludge digester effluents by the CANON process in an air pulsing SBR显示文摘 | J.R. Vázquez-Padín M.J. Pozo M. Jarpa M. Figueroa A. Franco A. Mosquera-Corral J.L. Campos R. Méndez | 2008 | Journal of Hazardous Materials2008，，1： | 2 |
| 4 | Inhibition of DYRK1A destabilizes EGFR and reduces EGFR - dependent glioblastoma growth 显示文摘 | Pozo N Zahonero C Fernandez P | 2013 | J Clin Invest2013，123，6： | 1 |
| 5 | The electricidal effect: reduction of Staphylococcus and Pseudomonas biofilms by prolonged exposure to low-intensity electrical current显示文摘 | del POZO J L ROUSE M S MANDREKAR J N | 2009 | Antimicrobial Agents and Chemotherapy2009，53，1： | 1 |
| 6 | Effect of electri- cal current on the activities of antimicrobial agents against Pseudomonas aeruginoso, Staphylococcus attreus, and Stapfiylococcus epidermidis biofilms显示文摘 | DEL POZO J L ROUSE M S MANDREKAR J N | 2009 | Antimicrob Agents Ch2009，53，1： | 1 |
| 7 | Inhibition of the seril proteases of the complement system 显示文摘 | Sarmiento E del Pozo N Gallego A | 2013 | Adv Exp Med Bi62013，735，： | 1 |
| 8 | Cop- per transport by lobster (Homarus americanus) hepatopancreat- ic lysosomes 显示文摘 | CHAVEZ-CROOKER P GARRIDO N POZO P | 2003 | Comp Biochem Physiol C : Toxicology and Pharmacology2003，135，2： | 1 |
| 9 | Prediction of press/die deformation for an accurate manufacturing of draw- ing dies 显示文摘 | Del Pozo D L6pez de Lacalle L N L6pez J M | 2008 | Journal of Advanced Manufacturing Technolo- gy2008，37，： | 1 |
| 10 | Increased circulating endothelial microparticles in COPD显示文摘 | García J Del Pozo R Coll N | 2013 | Eur Respir J2013，42，57： | 1 |
| 11 | Persistent Organic Pollutants (POPs) in the atmosphere of agricultural and urban areas in the Province of Buenos Aires in Argentina using P UF disk passive air samplers 显示文摘 | Tombesi N Pozo K Harner T | 2014 | Atmospheric Pollution Research2014，5，2： | 1 |
| 12 | SKP2A,an F-box protein that regulates cell division,is degraded via the ubiquitin pathway显示文摘 | Jurado S Diaz-Trivi(n)o S Abraham Z Manzano C Gutierrez C del Pozo JC | | 0，，： | 1 |
| 13 | The identification of KRAS mutations at codon 12 in plasma DNA is not a prognostic factor in advanced non-small cell lung cancer patients显示文摘 | Carlos Camps Eloisa Jantus-Lewintre Andrea Cabrera Ana Blasco Elena Sanmartín Sandra Gallach Cristina Caballero Nieves del Pozo Rafael Rosell Ricardo Guijarro Rafael Sirera | 2010 | Lung Cancer2010，，3： | 1 |
| 14 | Identification of ubiquitinated proteins in Arabidopsis显示文摘 | Manzano M Abraham Z López-Torrejón G Del Pozo JC | | 0，，： | 1 |
| 15 | Linezolid-Induced Lactic Acidosis in Two Liver Transplant Patients with the Mitochondrial DNA A2706G Polymorphism显示文摘 | del Pozo JL Fernández-Ros N Sáez E | 2014 | Antimicrob Agents Chemother2014，58，7： | 1 |
| 16 | Relevance of insulin-like growth factor 1 receptor gene expression as a prognostic factor in non-small-cell lung cancer显示文摘 | M. Teresa Agulló-Ortu?o C. Vanesa Díaz-García Alba Agudo-López Carlos Pérez Ana Cortijo Luis Paz-Ares Fernando López-Ríos Francisco Pozo Javier de Castro Hernán Cortés-Funes José A. López Martín | 2015 | Journal of Cancer Research and Clinical Oncology2015，，： | 1 |
| 17 | Pilot study of as- sociation of bacteria on breast implants with capsular contracture 显示文摘 | del POZO J L TRAN N V PETTY P M | 2009 | J Clin Microbiol2009，47，5： | 1 |
| 18 | Constant rateshearing on two-dimensional cohesive discs显示文摘 | OLIVI-TRAN N POZO O FRAYSSE N | 2005 | Journal ofPhysics-Condensed Matter2005，17，37： | 1 |
| 19 | Treatment of anaerobic sludge digester effluents by the CANON process in an air pulsing SBR显示文摘 | J R Vázquez-Padín M J Pozo b M Jarpa c | | 0，，： | 1 |
| 20 | Decreased levels of serum complement C3 and natural killer cells add to the predic- tive value of total immunoglobulin G for severe infection in heart transplant recipients 显示文摘 | Sarmiento E del Pozo N Gallego A | 2012 | Transpl Infect Dis2012，14，5： | 1 |
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