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| 1 | Requirement for cyclin D3 in germinal center formation and function显示文摘第二等的淋巴的纸巾的幼芽的中心(GC ) 对装高亲密关系的体液的有免疫力的回答批评。当多样化他们的抗体基因时,在 GC 以内的 B 房间经历快速的同种细胞的扩大和选择。尽管 GC B 房间采用一个唯一的 proliferative 程序提供这些进程,这通常被相信,很少联系 GC 的房间周期怎么被安排被知道。D 类型 cyclins 组成使房间能对生理的变化作出回应的房间周期引擎的一个重要部件。房间类型 -- 并且 D 类型 cyclins 的发展阶段特定的角色被描述了,但是 cyclin D 要求没在 GC 反应期间被探讨。在这研究,我们报导 cyclin D3 为切换的增长和 Ig 班大部分是非必需的在 vitro 激活的 B 房间。相反,在 Ccnd3 的 GC 开发 ?/ ?老鼠显著地被损害,作为是 T 房间依赖者抗体反应。在 GC 以内,尽管切换, unswitched B 房间被 cyclin D3 inactivation 影响, IgM?水池更严重地被减少。有趣地尽管有 cyclin D2 表示的补偿增加, Ccnd3 的一个重要数字 ?/ ?GC B 房间处于静止 G0 状态积累。最后,尽管 cyclin D3 inactivation 没在 GC B 房间破坏 BCL6 表示,支持 BCL6 overexpression 的效果完全堵住了 GC,建议 cyclin D3 调整 GC 形成的 BCL6 下游地行动。这是 cyclin D3 玩的第一示范在 B 房间开发的 GC 阶段的一个重要、唯一的角色。 | Jonathan U Peled J Jessica Yu Jeganathan Venkatesh Enguang Bi B Belinda Ding Melissa Krupski-Downs Rita Shaknovich Piotr Sicinski Betty Diamond Matthew D Scharff B Hilda Ye | 2010 | Cell Research2010，20，6： | 3 |
| 2 | Cooperatation between p53-dependent and p53-indepen-dent apototic pathways in myeloid cells显示文摘 | Peled A Zipori D Rotter V | 1996 | Cancer Res1996，569，9： | 1 |
| 3 | Enhancement of bone formation by bone morphogenetic protein-2 during alveolar distraction:an experimental study in sheep显示文摘 | Aizenbud D Peled M | 2004 | J Periodontol2004，75，11： | 1 |
| 4 | Springback of circular clamped armor steel plates subjected to spherical air-blast 19ading显示文摘 | Neuberger A Peles S Rittel D | 2009 | International Journal of Impact Engineering2009，36，： | 1 |
| 5 | In silico screening of a saturated mutation library of tomato 显示文摘 | Menda N Semel Y Peled D | 2004 | Plant Journal2004，38，： | 1 |
| 6 | Improved graphite anode for lithium-ion batteries-chemically bonded solid electrolyte interface and nanochannel formation显示文摘 | PELED E MENACHEM C BARTOW D | 1996 | J Electrochem Soc1996，143，1： | 1 |
| 7 | Guided bone regeneration for the treatment of cleft palate defects : A report of two cases 显示文摘 | Machtei EE Peled M Aizenbud D | 1999 | J Oral Maxillofac Surg1999，57，5： | 1 |
| 8 | Guided bone regenerat- ion for the treatment of cleft palate defects: A report of two cases 显示文摘 | Maehtei EE Peled M Aizenbud D | 1999 | J Oral Maxillofac Surg1999，57，5： | 1 |
| 9 | Enhancement of bone formation by bone morphogenetic protein-2 during alveolar distraction: an experimental study in sheep 显示文摘 | Rachmiel A Aizenbud D Peled M | 2004 | J Periodontol2004，75，11： | 1 |
| 10 | Ion-transport phenomena in concentrated PEO-based composite polymer electrolytes显示文摘 | Golodnitsky D Ardel G Peled E | 2002 | Solid State Ionics2002，147，： | 1 |
| 11 | Treatment of mandibular fractures by means of compression osteosynthesis显示文摘 | Peled M Laufer D Helman J | 1989 | J Oral Maxillofac Surg1989，47，6： | 1 |
| 12 | Enhancement of bone formation by bone morphogenetic protein-2 during alveolar distraction: an experimental study in sheep显示文摘 | Rachmiel A Aizenbud D Peled M | 2004 | J Periodontol2004，75，11： | 1 |
| 13 | Suppression of tumor growth and metastasis by dietary fish oil combined with vitamins E and C and cisplatin显示文摘 | Yam D Peled A Shinitzky M | 2001 | Cancer Chemother Pharmacol2001，47，1： | 1 |
| 14 | High bvalue q-space analyzed diffusion-weighted MRI: application to multiple sclerosis显示文摘 | Y Assaf D Ben-Bashat J Chapman S Peled | 2002 | MRM2002，47，12： | 1 |
| 15 | Enhancement of bone formation by bone morphogenetic protein-2 during alveolar distraction:an experimental study in sheep显示文摘 | Rachmiel A Aizenbud D Peled M | 2004 | J Periodontol2004，75，11： | 1 |
| 16 | Congenitally missing teeth in the Israeli cleft population显示文摘 | Aizenbud D Camasuvi S Peled M | 2005 | Cleft Palate Craniofae J2005，42，3： | 1 |
| 17 | Composition, depth profiles and lateral distribution of materials in the SEI built on HOPG-TOF SIMS and XPS studies显示文摘 | Peled E Bar Tow D Merson A | 2001 | Journal of power sources2001，9798，： | 1 |
| 18 | Study of phasechanges during 500 full cycles of Li/composite polymer elec-trolyte/FeS2 battery 显示文摘 | STRAUSS E GOLODNITSKY D PELED E | 2000 | Electrochimica Acta2000，45，： | 1 |
| 19 | Peripheral endothelial dysfunction in patients with pulmonary arterial hypertension显示文摘 | Peled N Bendayan D Shitrit D | 2008 | Respir Med2008，102，12： | 1 |
| 20 | Improved graphite anode for lithium-ion batteries显示文摘 | Menachem D Bar-Tow D | 1996 | J Electrochem Soc1996，143，： | 1 |
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