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| 1 | Picophytoplankton, nanophytoplankton, heterotrohpic bacteria and viruses in the Changjiang Estuary and adjacent coastal waters显示文摘 | Pan LA Zhang J Zhang LH | 2007 | 中国生物学文摘2007，21，7： | 11 |
| 2 | Gold nanoprisms as a hybrid in vivo cancer theranostic platform for in situ photoacoustic imaging, angiography, and localized hyperthermia显示文摘高分辨率的 nanosized photoacoustic 对比代理人的发展是令人激动的还挑战性的工艺的进展。此处,抗体(胸联系癌症的抗原 1 (Brcaa1 ) monoclonal 抗体)- 并且肽(RGD )-functionalized 金牌 nanoprisms (AuNprs ) 被用作组合方法论为在使用的 situ photoacoustic 成像, angiography,和局部性的过高热, orthotopic 和下的鼠科的胃的癌当模特儿。结合 RGD 的 PEGylated AuNprs 为结合抗体的 PEGylated AuNprs 被用于指向的肿瘤 angiography,和 Brcaa1 monoclonal 并且为是可得到的在在 orthotopic 的胃的癌的 situ 成像,肿瘤当模特儿。在 situ photoacoustic 成像允许在肿瘤地点的解剖、功能的成像。在 vivo 肿瘤 angiography,成像以一种时间依赖者方式显示出 photoacoustic 信号的改进。而且, photoacoustic 成像证明肿瘤容器清楚地在局部性的过高热以后被损坏。这作为高度敏感的对比和治疗学的代理人是用二根 AuNprs 探针的第一 proof-of-concept 为在 situ 肿瘤察觉和抑制。这些聪明的抗体 / 肽 AuNprs 能被用作一个有效 nanotheranostic 平台为在局部性的过高热处理以后在有高敏感的 vivo 肿瘤察觉,以及为指向治疗,与单个剂量的注射,它导致肿瘤的肿瘤缩放减小和增加老鼠幸存。 | Chenchen Bao Joao Conde Fei Pan Chao Li Chunlei Zhang Furong Tian Shujing Liang Jesus M. de la Fuente Daxiang Cui | 2016 | Nano Research2016，9，4： | 9 |
| 3 | New therapeutic opportunities for Hepatitis C based on small RNA显示文摘Hepatitis C virus (HCV) infection is one of the major causes of chronic liver disease, including cirrhosis and liver cancer and is therefore, the most common indication for liver transplantation. Conventional antiviral drugs such as pegylated interferon-alpha, taken in combination with ribavirin, represent a milestone in the therapy of this disease. However, due to different viral and host factors, clinical success can be achieved only in approximately half of patients, making urgent the requirement of exploiting alternative approaches for HCV therapy. Fortunately, recent advances in the understanding of HCV viral replication and host cell interactions have opened new possibilities for therapeutic intervention. The most recent technologies, such as small interference RNA mediated gene-silencing, anti-sense oligonucleotides (ASO), or viral vector based gene delivery systems, have paved the way to develop novel therapeutic modalities for HCV. In this review, we outline the application of these technologies in the context of HCV therapy. In particular, we will focus on the newly defined role of cellular microRNA (miR-122) in viral replication and discuss its potential for HCV molecular therapy. | Qiu-wei Pan Scot D Henry Bob J Scholte Hugo W Tilanus Harry LA Janssen Luc JW van der Laan | 2007 | World Journal of Gastroenterology2007，13，33： | 4 |
| 4 | High spin states in stable nucleus ^(84)Sr显示文摘High spin states of 84Sr were populated through the reaction 70Zn(18O,4n)84Sr at 75 MeV beam energy.Measurement of excitation function,γ-γ coincidences,directional correlation from oriented state (DCO) ratios and γ-transition intensities were performed using eight anticompton HPGe detectors and one planar HPGe detector.Based on the measured results,a new level scheme of 84Sr was established in which 12 new states and nearly 30 new γ-transitions were identified in the present work.The positive-parity states of the new level scheme were compared with the results from calculations in the framework of the projected shell model (PSM).One negative-parity band was extended to spin Iπ=19-and it can be found that in the high spin states,the γ-transition energies show the nature of signature staggering.The negative-parity band levels are in good agreement with deformed configuration-mixing shell model (DCM) calculations. | KANG XuZhong1,2,SHEN ShuiFa1,2,3,4*,HAN GuangBing5,PAN Feng3,4,GU JianZhong6,DRAAYER J P4,WU XiaoGuang6,ZHU LiHua6 & WEN TingDun7 1 Key Laboratory of Nuclear Resources and Environment (East China Institute of Technology),Ministry of Education,Nanchang 330013,China 2 School of Nuclear Engineering and Technology,East China Institute of Technology,Fuzhou 344000,China 3 Department of Physics,Liaoning Normal University,Dalian 116029,China 4 Department of Physics and Astronomy,Louisiana State University,Baton Rouge,LA 70803-4001,USA 5 School of Physics,Shandong University,Jinan 250100,China 6 China Institute of Atomic Energy,Beijing 102413,China 7 Department of Physics,North University of China,Taiyuan 030051,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，10： | 4 |
| 5 | Pretransplant xenogeneic blood transfusion combined with FK506 prolongs hamster-to-rat liver xenograft survival显示文摘 | Nardo B Valdiva LA Pan F | 1994 | Transplant Proc1994，26，3： | 1 |
| 6 | Radiation dosevolume effects in the stomach and small bowel显示文摘 | Kavanagh BD Pan CC Dawson LA | | 0，，03： | 1 |
| 7 | Genome sequence and analysis of the tuber crop potato显示文摘 | Xu X Pan S Cheng S Zhang B Mu D Ni P Zhang G Yang S Li R Wang J Orjeda G Guzman F Tones M Lnzano R Ponce O Martinez D De la Cruz G Chakrabarti S K Patil V U Skryabin K G Kuznetsov B B Ravin N V Kolganova T V Beletsky A V Mardanov A V Di Genova A Bolser D M Martin D M Li G Yang Y Kuang H Hu Q Xiong X Bishop G J Sagredo B Mejia N Zagorski W Gromadka R Gawor J Szczesny P Huang S Zhang Z Liang C He J Li Y He Y Xu J Zhang Y Xie B Du Y Qu D Bonierbale M Ghislain M Herrera Mdel R Giuliano G Pietrella M Perrotta G Faeella P O 'Brien K Feingold S E Barreiro L E Massa G A Diambra L Whitty B R Vaillancourt B Lin H Massa A N Geoffroy M Lundback S DellaPenna D Buell C R Sharma S K Marshall D F Waugh R Bryan G J Destefanis M Nagy I Milbourne D Thomson S J Fiefs M Jacobs J M Nielsen K L Sonderkaer M Iovene M Tortes G A Jiang J Veilleux R E Bachem C W de Boer J Bonn T Kloosterman B van Eck H Datema E Hekkert B Goverse A van Ham R C Visser R G | 2011 | Nature2011，475，7355： | 1 |
| 8 | Exposure in utero to 2,2', 3,3', 4,6' -hexachlorobiphenyl ( PCB 132 ) impairs sperm function and alters testicular apoptosis-related gene expression in rat offspring 显示文摘 | Hsu PC Pan MH Li LA Chen CA Tsai SS Guo YL | 2007 | Toxicol Appl Pharmacol2007，221，1： | 1 |
| 9 | Functional character-ization of a cloned pig intestinal peptide transporter显示文摘 | Klang JE Burnworth LA Pan YX | 2005 | J Animal Science2005，83，1： | 1 |
| 10 | Differential patterns of ac- tivity and functional connectivity in emotion processing neural circuitry to angry and happy faces in adolescents with and without suicide at- tempt显示文摘 | Pan LA Hassel S Segreti AM | 2013 | Psychological Medicine2013，43，10： | 1 |
| 11 | Temperature extremes and mortality from coronary heart disease and cerebral infarction in elderly Chinese 显示文摘 | Pan WH Li LA Tsai MJ | 1995 | The Lancet1995，345，： | 1 |
| 12 | Evaluation of 5 - ethynyl - 2'- de - oxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system 显示文摘 | Zeng C Pan F Jones LA | 2010 | Brain Res2010，1379，10： | 1 |
| 13 | The fatty acid composition of skeletal muscle membrane phospholipid: its relationship with the type of feeding and plasma glucose levels in young children显示文摘 | Baur LA O'Connor J Pan DA | 1998 | Metabolism1998，47，： | 1 |
| 14 | Predicting protein subcellular locationusing wavelet analysis显示文摘 | Pan Y X La Y J Feng G Y | 2008 | Journal of Ningxia University (Natural Science Edition)2008，29，3： | 1 |
| 15 | Differentiation state determines neural effects on microvascular endothelial cells显示文摘 | Muffley LA Pan SC Smith AN | | 0，，： | 1 |
| 16 | Functional character - ization of a cloned pig intestinal peptide transporter 显示文摘 | Klang JE Burnworth LA Pan YX | 2005 | J Anim Sci2005，83，1： | 1 |
| 17 | Endochronic equations for finite plastic deformation and application to metal tube under tomion显示文摘 | Wu H C La J K Pan W F | 1995 | Int J Solids Structures1995，32，89： | 1 |
| 18 | Evaluation of 5-ethynyl-2'-deoxyuri- dine staining as a sensitive and reliable method for studying cell prolif- eration in the adult nervous system 显示文摘 | Zeng C Pan F Jones LA | 2010 | Brain Res2010，1319，： | 1 |
| 19 | Evaluation of 5-ethynyl-2'-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system显示文摘 | Zeng C Pan F Jones LA | | 0，，： | 1 |
| 20 | Endochronic equations for finite plastic deformation and application to metal tube under torsion显示文摘 | Wu H C La J K Pan W F | 1995 | Int J Solids Structures1995，32，89： | 1 |
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